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autologous blood patch pleurodesis

Daniel G French, Madelaine Plourde, Harry Henteleff, Aneil Mujoomdar, Drew Bethune
Air leaks are the most common complication after pulmonary resection. Enhanced recovery after surgery (ERAS) programs must be designed to manage parenchymal air leaks. ERAS programs should consider two components when creating protocols for air leaks: assessment and management. Accurate assessment of air leaks using traditional analogues devices, newer digital drainage systems, portable devices and chest X-rays (CXR) are reviewed. Published data suggests that digital drainage systems result in a more confident assessment of air leaks...
November 2018: Journal of Thoracic Disease
Filipe Moreira De Andrade, Marcelo Reis Pereira, Renan Liboreiro Kilesse, Bruno Dos Santos Farnetano
No abstract text is available yet for this article.
July 2018: Lung India: Official Organ of Indian Chest Society
Islam M Ibrahim, Montaser Elsawy Abd Elaziz, Mohammed Ahmed El-Hag-Aly
BACKGROUND:  Autologous blood-patch pleurodesis has been effectively utilized as a treatment option for the condition of secondary spontaneous pneumothorax (SSP). Moreover, it can be used with persistent air leak, with or without residual air space. However, there have been no robust reports for the optimal timing for autologous blood-patch pleurodesis. The aim of this study is to compare early autologous blood-patch pleurodesis with conservative management of SSP. METHODS:  We conducted a randomized controlled study at the Menoufia University Hospital...
April 19, 2018: Thoracic and Cardiovascular Surgeon
Karen C Dugan, Balaji Laxmanan, Septimiu Murgu, D Kyle Hogarth
Alveolar-pleural fistulas causing persistent air leaks (PALs) are associated with prolonged hospital stays and high morbidity. Prior guidelines recommend surgical repair as the gold standard for treatment, albeit it is a solution with limited success. In patients who have recently undergone thoracic surgery or in whom surgery would be contraindicated based on the severity of illness, there has been a lack of treatment options. This review describes a brief history of treatment guidelines for PALs. In the past 20 years, newer and less invasive treatment options have been developed...
August 2017: Chest
R J Hallifax, A Yousuf, H E Jones, J P Corcoran, I Psallidas, N M Rahman
OBJECTIVES: Spontaneous pneumothorax is a common pathology. International guidelines suggest pleurodesis for non-resolving air leak or recurrence prevention at second occurrence. This study comprehensively reviews the existing literature regarding chemical pleurodesis efficacy. DESIGN: We systematically reviewed the literature to identify relevant randomised controlled trials (RCTs), case-control studies and case series. We described the findings of these studies and tabulated relative recurrence rates or ORs (in studies with control groups)...
December 2017: Thorax
Serdar Evman, Levent Alpay, Serda Metin, Hakan Kıral, Mine Demir, Murat Yalçinsoy, Volkan Baysungur, Irfan Yalçinkaya
INTRODUCTION: Prolonged air leak in secondary spontaneous pneumothorax (SSP) patients remains one of the biggest challenges for thoracic surgeons. This study investigates the feasibility, effectiveness, clinical outcomes, and economical benefits of the autologous blood patch pleurodesis method in SSP. MATERIAL AND METHODS: First-episode SSP patients undergoing autologous blood patch pleurodesis for resistant air leak following underwater-seal thoracostomy, between January 2010 and June 2013 were taken into the study...
March 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
Alvaro Navarro Mingorance, María Dolores Pastor Vivero, Maria Cruz León León, Susana Beatriz Reyes Domínguez, Jose Luis Fuster Soler
No abstract text is available yet for this article.
September 2016: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Katsunori Kagohashi, Gen Ohara, Toshihiro Shiozawa, Tomohiro Tamura, Kunihiko Miyazaki, Koichi Kurishima, Hiroaki Satoh, Nobuyuki Hizawa
Pneumothorax in patients with progressive systemic sclerosis (PSS) often presents as a difficult-to-treat disease. Autologous blood-patch pleurodesis has previously been used for the treatment of pneumothorax. Blood outside its own environment is an irritant; therefore, chest physicians must watch closely for an allergic reaction. The injection is simple, painless, causes no side effects, is an inexpensive treatment for pneumothorax and is available not only in patients with persistent air leak but also in those with residual air space...
December 2014: Experimental and Therapeutic Medicine
Nama Oppenheimer, Sigal Klainbart, Yael Merbl, Yaron Bruchim, Josh Milgram, Efrat Kelmer
OBJECTIVE: To describe the clinical course, outcome and success rate of 8 dogs with persistent pneumothorax treated with autologous blood-patch pleurodesis (ABP). DESIGN: Retrospective case series. SETTING: University teaching hospital ANIMALS: Eight client-owned dogs. INTERVENTION: Non-coagulated blood was aseptically collected from the jugular vein and injected immediately into the pleural cavity of dogs with persistent pneumothorax...
March 2014: Journal of Veterinary Emergency and Critical Care
Joseph B Lillegard, Raelene D Kennedy, Michael B Ishitani, Abdalla E Zarroug, Brad Feltis
PURPOSE: Persistent air leak (PAL) is associated with increased morbidity. Standard treatment of PAL includes chemical or mechanical pleurodesis. Long-term impact of these interventions is not known in the pediatric population. Autologous blood patch (ABP) offers a novel treatment option. We report our experience with autologous blood patch to successfully treat PAL in eight children. METHODS: Children with PAL were treated with ABP. A fresh whole blood sample was obtained from each patient and injected via their pre-existing chest tube...
September 2013: Journal of Pediatric Surgery
LaDonna J Malone, Robert M Stanfill, Huaping Wang, Kevin M Fahey, Raymond E Bertino
OBJECTIVE: The purpose of this study was to determine whether an autologous intraparenchymal blood patch reduces the rate of pneumothorax and the rate of pneumothorax requiring chest tube placement after percutaneous lung biopsy. SUBJECTS AND METHODS: A prospective randomized controlled trial enrolling 242 patients was conducted. Adult patients undergoing percutaneous biopsy of lung or mediastinal lesions of undetermined cause were candidates. Patients were excluded if aerated lung tissue was not crossed during the biopsy...
June 2013: AJR. American Journal of Roentgenology
Satoshi Iyama, Tsutomu Sato, Kazuyuki Murase, Shohei Kikuchi, Yusuke Kamihara, Kaoru Ono, Kohichi Takada, Koji Miyanishi, Yasushi Sato, Rishu Takimoto, Masayoshi Kobune, Takuro Obama, Masahiro Miyajima, Atsushi Watanabe, Tetsuya Higami, Yasuo Hirayama, Junji Kato
Pneumothorax associated with chronic graft-versus-host disease (cGVHD) after stem cell transplantation is a rare complication. Autologous blood has been used successfully for pleurodesis, which was less toxic than chemical agents. However, when pneumothorax is resistant to pleurodesis, no other procedure is more effective and conservative. Here, we describe a case of myelodysplastic syndromes complicated with cGVHD-related pneumothorax. His pneumothorax has been resistant to pleurodesis using autologous blood and was treated successfully with fibrin glue sealant...
2012: Internal Medicine
Kate Manley, Aman Coonar, Frank Wells, Marco Scarci
PURPOSE OF REVIEW: Persistent air leak (PAL) poses a significant challenge to the thoracic surgeon. Of the numerous methods employed to manage this problem, autologous blood 'patch' pleurodesis (ABPP) remains one of the most controversial, seemingly due to a lack of robust data and consensus of opinion regarding its efficacy, technique of application and its role in clinical practice. Despite a lack of randomized control trials, the evidence to-date has shown ABPP to be an efficacious, cheap, simple, well tolerated and readily available treatment, with minimal side effects and broad range of applications, allowing for earlier chest drain removal, decreased complications and decreased hospital stay...
July 2012: Current Opinion in Pulmonary Medicine
Guo qiang Cao, Jun Kang, Fangwen Wang, Hucheng Wang
BACKGROUND: We evaluated the safety and efficacy of increasing doses of autologous blood patch pleurodesis in treating persistent air leaks in patients with advanced chronic obstructive pulmonary disease (COPD). METHODS: Forty-four patients with COPD and spontaneous pneumothorax (SP) on the 7th day after intercostal tube drainage were randomly assigned to 4 groups, with 11 patients in each group. Groups A, B, and C were given increasing doses of autologous blood--ie, 0...
May 2012: Annals of Thoracic Surgery
Jason M Wagner, J Louis Hinshaw, Meghan G Lubner, Jessica B Robbins, David H Kim, Perry J Pickhardt, Fred T Lee
OBJECTIVE: The objective of our study was to determine whether pleural blood patching reduces the need for chest tube placement and hospital admission for pneumothorax complicating CT-guided percutaneous lung biopsy. MATERIALS AND METHODS: We reviewed 463 CT-guided lung biopsies performed between August 2006 and March 2010 to determine whether intervention for pneumothorax was required and patient outcome. Intervention was categorized as simple aspiration, aspiration and intrapleural blood patching, or chest tube placement and hospital admission...
October 2011: AJR. American Journal of Roentgenology
Kensaku Aihara, Tomohiro Handa, Sonoko Nagai, Kiminobu Tanizawa, Kizuku Watanabe, Yuka Harada, Yuichi Chihara, Takefumi Hitomi, Toru Oga, Tomomasa Tsuboi, Kazuo Chin, Michiaki Mishima
OBJECTIVE: We identified the prognostic relevance of pneumothorax in interstitial lung disease (ILD) patients and evaluated the efficacy and safety of autologous blood-patch pleurodesis. METHODS: We retrospectively reviewed 59 occurrences of pneumothorax in 34 ILD patients identified over a 12-year period. RESULTS: Air leakage ceased in 16 of 22 (72.7%) episodes after blood pleurodesis and in 11 of 14 (78.6%) episodes after chemical pleurodesis...
2011: Internal Medicine
B Ozpolat
OBJECTIVE: Prolonged air leak is a common problem for thoracic surgeons. In this study, the efficacy of autologous blood patch pleurodesis for prolonged air leak in spontaneous pneumothorax and secondary to pulmonary hydatid cyst operations was evaluated. METHODS: Between 1997 and 2007, autologous blood patch pleurodesis was used to treat prolonged air leak in 24 patients. Prolonged air leak was due to spontaneous pneumothorax in 17 patients and secondary to pulmonary hydatid cyst operation in 7 patients...
February 2010: Thoracic and Cardiovascular Surgeon
Claudio Andreetti, Federico Venuta, Marco Anile, Tiziano De Giacomo, Daniele Diso, Mario Di Stasio, Erino A Rendina, Giorgio Furio Coloni
OBJECTIVE: Air leakage after pulmonary lobectomy is a well-known problem often contributing to extended hospitalization. Many techniques have been proposed to prevent and treat air leakage, but none have been proved incontrovertibly effective. We evaluated the role of an autologous blood patch after pulmonary lobectomy. METHODS: Twenty-five patients with air leaks on the sixth postoperative day after lobectomy were enrolled in this study. They were randomly assigned to 2 groups: group A (12 patients), with 50 mL of autologous blood infused in the pleural cavity; and group B (13 patients), with 100 mL of blood infused...
March 2007: Journal of Thoracic and Cardiovascular Surgery
Vittore Pagan, Paolo Fontana, Antonio Zaccaria, Fabio Lo Giudice, Andrea Ferronato, Rosario Salvi, Alessandro Busetto
Persistent air leak (PAL) is the most common complication after lung resection, requiring additional treatments and hospital stay. Intraoperative prevention of PAL is usually left to the surgeon's subjective judgement, with inconsistent results. The aim of the study was to establish systematic, reproducible quantification of air leaks at thoracotomy in order to identify those which are potentially persistent, to be preventively treated by intraoperative "blood patch" pneumo-stasis. In a consecutive series of 570 lung resections, parenchymal suture air tightness was tested intraoperatively at end-inspiratory pressure intervals from 15 to 35 cm H2O...
July 2006: Chirurgia Italiana
Andrea Droghetti, Andrea Schiavini, Piergiorgio Muriana, Andrea Comel, Giuseppe De Donno, Massimiliano Beccaria, Barbara Canneto, Carlo Sturani, Giovanni Muriana
OBJECTIVE: Persistent air leak is among the most common complications after pulmonary resection, leading to prolonged hospitalization and increased costs. At present there is not yet a consensus on their treatment. METHODS: During a 7-year experience, 21 patients submitted to pulmonary resection were postoperatively treated with an autologous blood patch for persistent air leaks. Persistent air leaks were catalogued twice daily according to the classification previously reported by Cerfolio and associates...
September 2006: Journal of Thoracic and Cardiovascular Surgery
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