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Stroke OR cerebrovascular Accident

Rolf F Barth, Sergey V Brodsky, Miroljub Ruzic
Joseph Stalin was one of the most important world leaders during the first half of the 20th century. He died suddenly in early March 1953 after a short illness, which was described in a series of medical bulletins in the Soviet newspaper Pravda. Based on both the clinical history and autopsy findings, it was concluded that Stalin had died of a massive hemorrhagic stroke involving his left cerebral hemisphere. However, almost 50 years later, a counter-narrative developed suggesting a more nefarious explanation for his sudden death, namely, that a "poison," warfarin, a potent anticoagulant, had been administered surreptitiously by one or more of his close associates during the early morning hours prior to the onset of his stroke...
February 20, 2019: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
Manik K Gupta, Jasvinder A Singh
Cardiovascular disease affects more than 90 million Americans. Recent studies support an increased cardiovascular disease risk in inflammatory conditions, such as gout. Increased serum urate levels, or hyperuricemia, are a precursor to gout. Data from meta-analyses have shown hyperuricemia to be linked to hypertension and coronary heart disease. Similarly, gout has been associated with an increased risk of myocardial infarction, cerebrovascular accidents, and death from cardiovascular disease in randomized clinical trials...
March 13, 2019: Drugs
Ting-An Lin, Jyh-Pyng Gau, Yao-Chung Liu, Po-Shen Ko, Hao-Yuan Wang, Sheng-Hsuan Chien, Chia-Jen Liu, Liang-Tsai Hsiao, Tzeon-Jye Chiou, Jin-Hwang Liu
Cerebrovascular complications after hematopoietic stem cell transplantation (HSCT) cause serious morbidity and often contribute to mortality. The incidence, risk factors, and outcome of cerebrovascular disease (CVD) after allogeneic HSCT remain poorly defined. We retrospectively evaluated 459 adult patients who underwent allogeneic HSCT at a tertiary medical center between January 2003 and December 2015. A total of 20 patients (4.4%) developed post-transplant CVD. All cerebrovascular accidents occurred in the first two years post-transplant...
March 12, 2019: International Journal of Hematology
Michael Teitelbaum, Rafail A Kotronias, Luciano A Sposato, Rodrigo Bagur
Cerebrovascular accidents including stroke or transient ischaemic attack are one of the most feared complications after transcatheter aortic valve implantation. Transcatheter aortic valve implantation procedures have been consistently associated with silent ischaemic cerebral embolism as assessed by diffusion-weighted MRI. To reduce the risk of cerebrovascular accidents and silent emboli, cerebral embolic protection devices were developed with the aim of preventing procedural debris reaching the cerebral vasculature...
February 2019: Interventional Cardiology
Luca Testa, Gaetano Pero, Mario Bollati, Matteo Casenghi, Antonio Popolo Rubbio, Magdalena Cuman, Mauro Agnifili, Samuele Pizzocri, Francesco Bedogni
The introduction into clinical practice of transcatheter aortic valve implantation (TAVI) has led to a significant change in the therapeutic paradigm for patients with valvular aortic stenosis. However, in parallel with the benefits obtained in prognosis and quality of life, an inherent risk of major cerebral thromboembolic events has been observed. In different studies this risk has been estimated between 2% and 6%. In order to reduce the incidence of cerebrovascular accidents during TAVI, several brain protection systems have been developed but, to date, none has obtained sufficient clinical evidence to be implemented on a large scale, and they are therefore used only in selected cases...
March 2019: Giornale Italiano di Cardiologia
G Soppa, P Theodoropoulos, R Bilkhu, D A Harrison, R Alam, R Beattie, D Bleetman, A Hussain, S Jones, L Kenny, M Khorsandi, A Lea, Ka Mensah, T N Hici, A C Pinho-Gomes, L Rogers, A Sepehripour, S Singh, D Steele, H Weaver, A Klein, N Fletcher, M Jahangiri
INTRODUCTION: We examine the influence of variations in provision of cardiac surgery in the UK at hospital level on patient outcomes and also to assess whether there is an inequality of access and delivery of healthcare. Cardiothoracic surgery has pioneered the reporting of surgeon-specific outcomes, which other specialties have followed. We set out to identify factors other than the individual surgeon, which can affect outcomes and enable other surgical specialties to adopt a similar model...
March 11, 2019: Annals of the Royal College of Surgeons of England
Theresa Winhusen, Jeff Theobald, David C Kaelber, Daniel Lewis
BACKGROUND AND AIMS: Screening for substance use disorder (SUD) in general medical settings may be particularly important in patients with comorbid health conditions exacerbated by SUD. This study evaluated whether SUD is associated with type 2 diabetes mellitus (T2DM)-complications in patients with co-occurring T2DM and hypertension. DESIGN: Analysis of a limited data set obtained through IBM Watson Health Explorys, a platform integrating data from electronic health records...
March 9, 2019: Addiction
Stephen J Fenton, Madison M Hunt, Pamela S Ropski, Eric R Scaife, Katie W Russell
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) has been used in the non-trauma setting for over 30 years. However, the use of ECMO in trauma remains a difficult question, as the risk of bleeding must be weighed against the benefits of cardiopulmonary support. METHODS: Retrospective review of children who sustained severe thoracic trauma (chest abbreviated injury score ≥3) and required ECMO support between 2009 and 2016. RESULTS: Of the 425 children who experienced severe thoracic trauma, 6 (1...
February 24, 2019: Journal of Pediatric Surgery
Panyun Wu, Fei Luo, Zhenfei Fang
BACKGROUND: Early revascularization can lead to better prognosis in multivessel coronary artery disease (CAD) patients with chronic kidney disease (CKD). However, whether coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) is better remains unknown. METHODS: We searched PubMed and the Cochrane Library database from inception until December 9, 2017, for articles that compare outcomes of CABG and PCI in multivessel CAD patients with CKD...
March 7, 2019: Cardiorenal Medicine
Stefaan Six, Steven Laureys, Jan Poelaert, Johan Bilsen, Peter Theuns, Liza Musch, Reginald Deschepper
BACKGROUND: Awareness and pain during palliative sedation is typically assessed by observational scales, but the use of such scales has been put into question. CASE PRESENTATION: A woman in her mid-80s was admitted to a palliative care unit, presenting with chronic lymphatic leukemia, depression, and a cerebrovascular accident, with right-sided hemiplegia and aphasia. The patient was unable to eat and was suffering from nausea and vomiting. Before admission, the patient had expressed her desire to discontinue treatment on several occasions...
March 7, 2019: Palliative Medicine
Mahmoud Barbarawi, Yazan Zayed, Kewan Hamid, Babikir Kheiri, Owais Barbarawi, Saira Sundus, Laith Rashdan, Ahmad Alabdouh, Adam Chahine, Ghassan Bachuwa, Moahmmad Luay Alkotob
BACKGROUND: Treatment of left main coronary artery disease (LMCAD) in patients with chronic kidney disease (CKD) with either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) remains controversial. Therefore, we performed a meta-analysis to evaluate the optimal choice of therapy when treating LMCAD in patients with CKD. METHOD: We performed an electronic database search of Pubmed, Embase, and Cochrane Library for all studies that compared PCI with CABG when treating LMCAD in the setting of CKD...
February 25, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Ellen Green, Annette Huynh, Lori Broussard, Brady Zunker, Jerril Matthews, Claudia L Hilton, Karen Aranha
This systematic review examines the efficacy of yoga as a neuromuscular intervention for community-dwelling populations at risk for falls to determine its utility for use in occupational therapy intervention. Populations included older adults and adults with traumatic brain injury (TBI), cerebrovascular accident (CVA), dementia and Alzheimer's disease (AD)-type dementia, multiple sclerosis (MS), and Parkinson's disease (PD). Benefits of yoga include improved posture control, improved flexibility of mind and body, relaxation, and decreased anxiety and stress...
January 2019: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
Eliane Gonçalves de Jesus Fonseca, Ariele Pedroso, Débora Neuls, Danilo Barbosa, Francisco José Cidral-Filho, Afonso Shiguemi Inoue Salgado, Angela Dubiela, Emerson Carraro, Ivo Ilvan Kerppers
Cerebrovascular accidents (CVAs), commonly known as strokes, can damage the brain through vascular injuries caused by either blood vessel blockages (ischemic stroke) or ruptures (hemorrhagic stroke) which disrupt regular brain blood supply and can cause severe damage to the individual. The objective of the present study was to evaluate the effects of photobiomodulation with a light-emitting diode (LED) device (904 nm, 110 mW, 7 J/cm2 ) on neurogenesis, muscle resistance, and motor behavior in animals submitted to an experimental model of hemiplegia...
March 2, 2019: Lasers in Medical Science
Joanne Guay, Sandra Kopp
BACKGROUND: General anaesthesia combined with epidural analgesia may have a beneficial effect on clinical outcomes. However, use of epidural analgesia for cardiac surgery is controversial due to a theoretical increased risk of epidural haematoma associated with systemic heparinization. This review was published in 2013, and it was updated in 2019. OBJECTIVES: To determine the impact of perioperative epidural analgesia in adults undergoing cardiac surgery, with or without cardiopulmonary bypass, on perioperative mortality and cardiac, pulmonary, or neurological morbidity...
March 1, 2019: Cochrane Database of Systematic Reviews
Takashi Kakuta, Satsuki Fukushima, Kimito Minami, Yusuke Shimahara, Takuma Yamasaki, Yorihiko Matsumoto, Kizuku Yamashita, Naonori Kawamoto, Naoki Tadokoro, Daijiro Kabata, Junjiro Kobayashi, Tomoyuki Fujita
OBJECTIVES: As an institutional strategy, the CryoMaze procedure has been established for treating atrial fibrillation (AF) since 2001. In this study, we aimed to analyse the contemporary outcomes of the CryoMaze procedure and to examine the predictive factors of successful sinus rhythm conversion. METHODS: Between January 2009 and March 2018, we performed 352 CryoMaze procedures. The contemporary outcomes of the CryoMaze procedure concomitant with other cardiac procedures were analysed by the Kaplan-Meier method...
February 28, 2019: Interactive Cardiovascular and Thoracic Surgery
Alam Sarfraz, Parveen Akhtar, Syed N Hassan Rizvi, Musa Karim
Introduction Coexistence of atrial fibrillation (AF) in patients with heart failure (HF) is a common phenomenon associated with poor prognosis. Therefore, this study was designed with an aim to estimate the different risk factors of atrial fibrillation (AF) in patients with HF. Methods In this study, patients of either gender, 18 to 80 years of age, and with echocardiographic confirmation of HF presenting at the adult cardiology department of the National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan were consecutively included...
December 24, 2018: Curēus
Benjamin Best, Ha S Nguyen, Ninh B Doan, Michael Gelsomino, Saman Shabani, Ghazaleh Ahmadi Jazi, Mohsen Sadati, Sarvenaz Sheikh, Farzad H Adl, Muhammad A Taqi, Martin M Mortazavi
BACKGROUND: Glioblastoma (GB) and its variants portend a poor prognosis. The predominant cause of death (COD) is related to the cancer diagnosis, but a significant subset is related to other causes. As GB is a systemic disease requiring systemic treatment, focus regarding all COD provides a comprehensive illustration of the disease. METHODS: The SEER-18 was queried for patients with cranial GB and its variants. Age, gender, race, marital status, tumor characteristics, treatment details, and follow-up data were acquired...
April 2019: Journal of Neurosurgical Sciences
R Kandaswamy, P G Stock, S K Gustafson, M A Skeans, R Urban, A Fox, J S Odorico, A K Israni, J J Snyder, B L Kasiske
In 2017, 1492 patients were added to the pancreas transplant waiting list, 964 listed as active, a slight increase from 2016. This is significant because for the first time in the past decade, the steady downward trend in additions to the waiting list has been reversed. Proportions of pancreas donors with cerebrovascular accident as cause of death decreased, with a concomitant increase in proportions with anoxia and head trauma. This is partly a result of the national opioid crisis, and it reflects increasing use of younger donors for pancreas transplant...
February 2019: American Journal of Transplantation
Stacy Willner, Zaid Imam, Ismail Hader
Rothia dentocariosa , a gram-positive coccobacillus, is a commensal bacterium that is part of the oropharynx and respiratory tract. In the past, it was known to be a cause for periodontal disease, but in recent years, Rothia dentocariosa has been found to be the cause of several other infectious entities, of which endocarditis is the most predominant. We present the case of a healthy 62-year-old female who, after undergoing routine dental cleaning two months prior, developed subacute bacterial endocarditis of the mitral valve, with subsequent cerebral septic emboli causing an occipital hemorrhagic cerebrovascular accident, all secondary to Rothia dentocariosa ...
2019: Case Reports in Cardiology
Mirthala Flores-Garcia, Juan Manuel Fernández-G, Cristina Busqueta-Griera, Elizabeth Gomez, Simon Hernandez-Ortega, Jean Christian Daniel Lamothe-Flores, Virginia Gomez-Vidales, Ana Maria Mejia-Dominguez, Eduardo Angles-Cano, Aurora de la Pena-Diaz
BACKGROUND: Ischemic heart disease, cerebrovascular accident, and venous thromboembolism have the presence of a thrombotic event in common and represent the most common causes of death within the population. OBJECTIVE: Since Schiff base copper(II) complexes are able to interact with polyphosphates (PolyP), a procoagulant and potentially prothrombotic platelet agent, we investigated the antiplatelet aggregating properties of two novel tridentate Schiff base ligands and their corresponding copper(II) complexes...
February 22, 2019: Medicinal Chemistry
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