keyword
https://read.qxmd.com/read/38533149/a-case-report-of-pediatric-rehabilitation-for-hypoxic-ischemic-encephalopathy-associated-with-global-developmental-delay
#1
Prajyot Ankar, H V Sharath, Nitika Chavan
Hypoxic ischemic encephalopathy (HIE) is a critical condition affecting neonates due to oxygen deprivation and insufficient flow of blood to the brain. It is associated with high neonatal mortality and the risk of developmental psychomotor disorders, including cerebral palsy. The global epidemiology of HIE reveals significant disparities, with more advanced healthcare systems reporting lower incidence rates. The aim of the study is to contribute to the understanding of effective rehabilitation strategies for children with HIE and global developmental delay (GDD), with the goal of improving outcomes and quality of life for these individuals...
February 2024: Curēus
https://read.qxmd.com/read/38530509/health-related-quality-of-life-impacts-associated-with-transfusion-dependent-%C3%AE-thalassemia-in-the-usa-and-uk-a-qualitative-assessment
#2
JOURNAL ARTICLE
Jennifer Drahos, Adriana Boateng-Kuffour, Melanie Calvert, Laurice Levine, Neelam Dongha, Nanxin Li, Zahra Pakbaz, Farrukh Shah, Antony P Martin
BACKGROUND: Individuals living with transfusion-dependent β-thalassemia (TDT) experience reduced health-related quality of life due to fatigue and chronic pain, which cause disruptions to daily life. Currently, limited qualitative data exist that describe these impacts. OBJECTIVE: This study aimed to examine the ways in which symptoms and current treatments of TDT impact health-related quality of life, to holistically describe the humanistic burden of TDT, and to identify the unmet needs of individuals living with TDT...
March 26, 2024: Patient
https://read.qxmd.com/read/38528650/review-of-systemic-mock-circulation-loops-for-evaluation-of-implantable-cardiovascular-devices-and-biological-tissues
#3
REVIEW
Emmanouil Agrafiotis, Daniel Zimpfer, Heinrich Mächler, Gerhard A Holzapfel
On needs-based ex vivo monitoring of implantable devices or tissues/organs in cardiovascular simulators provides new insights and paves new paths for device prototypes. The insights gained could not only support the needs of patients, but also inform engineers, scientists and clinicians about undiscovered aspects of diseases (during routine monitoring). We analyze seminal and current work and highlight a variety of opportunities for developing preclinical tools that would improve strategies for future implantable devices...
March 25, 2024: Journal of Endovascular Therapy
https://read.qxmd.com/read/38525553/effect-of-nurse-physician-collaboration-on-the-incidence-of-complications-negative-emotions-and-quality-of-life-in-cervical-cancer-patients-a-randomized-controlled-study
#4
JOURNAL ARTICLE
Ping Guan, Xingping Han, Dan Li, Bizhen Liao
The aim of this study was to evaluate the effect of nurse-physician collaboration on the incidence of complications, anxiety and depression, quality of life, and satisfaction with nursing care among cervical cancer patients undergoing three-dimensional intracavitary brachytherapy. In this randomized, single-blinded, placebo-controlled trial, 92 eligible cervical cancer patients were equally divided into two groups upon admission. The control group was given routine nursing, and the intervention group received a nurse-physician collaboration in addition to routine care...
March 25, 2024: Journal of Interprofessional Care
https://read.qxmd.com/read/38524044/naturopathic-interventions-for-reduction-of-perceived-pain-in-patients-suffering-from-arthritis-a-systematic-review-and-meta-analysis
#5
REVIEW
Himel Mondal, Satyalakshmi Komarraju, Sathyanath D, Shrikanth Muralidharan
Arthritis affects millions of lives with its pervasive effects on physical health and quality of life. Addressing the complexities of managing symptoms such as swelling, inflammation, and pain requires prolonged treatment. Naturopathy is a treatment method that enhances the body's innate ability to restore optimal health through a holistic approach including natural products and lifestyle modifications. This systematic review addresses the intersection of naturopathy and arthritis treatment to provide current evidence about its potential benefits...
February 2024: Curēus
https://read.qxmd.com/read/38523910/the-potential-role-of-artificial-intelligence-in-the-clinical-management-of-hansen-s-disease-leprosy
#6
JOURNAL ARTICLE
Patrícia D Deps, Rie Yotsu, Brunna C R S Furriel, Bruno D de Oliveira, Sergio L de Lima, Rafael M Loureiro
Missed and delayed diagnoses of Hansen's disease (HD) are making the battle against it even more complex, increasing its transmission and significantly impacting those affected and their families. This strains public health systems and raises the risk of lifelong impairments and disabilities. Worryingly, the three countries most affected by HD witnessed a growth in new cases in 2022, jeopardizing the World Health Organization's targets to interrupt transmission. Artificial intelligence (AI) can help address these challenges by offering the potential for rapid case detection, customized treatment, and solutions for accessibility challenges-especially in regions with a shortage of trained healthcare professionals...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38523042/consensus-of-the-brazilian-association-of-hematology-hemotherapy-and-cellular-therapy-on-patient-blood-management-definition-of-patient-blood-management
#7
JOURNAL ARTICLE
Juan Carlos Montano-Pedroso, Maria Cristina Martins de Almeida Macedo, Silvana Biagini, Glaciano Ribeiro, José Francisco Comenalli Marques Junior, Silvia Renata Cornélio Parolin Rizzo, Guilherme Rabello, Dante Mario Langhi Junior
Managing the patient's blood and hematopoietic system is like managing any of the other organs and organ systems during patient care. Specialists control the heart, kidneys, endocrine system, etc. and the patient's blood requires similar clinical treatment. The hematopoietic system and its circulatory products are fundamental for the healthy functioning of the human body. In simple terms, Patient Blood Management (PBM) is an organized, patient-centered approach in which the entire healthcare team coordinates efforts to improve outcomes by managing and preserving the patient's own blood...
March 8, 2024: Hematology, Transfusion and Cell Therapy
https://read.qxmd.com/read/38520734/-it-s-not-just-linguistically-there-s-much-more-going-on-the-experiences-and-practices-of-bilingual-paediatric-speech-and-language-therapists-in-the-uk
#8
JOURNAL ARTICLE
Mélanie Gréaux, Jenny L Gibson, Napoleon Katsos
BACKGROUND: Despite the high prevalence of bilingualism in the United Kingdom, few speech and language therapists (SLTs) are bilingual themselves. Most SLT research on bilingualism has generated knowledge to inform service delivery for bilingual clients, but few studies have investigated how being a bilingual SLT influences one's professional experiences and practices. Better understanding the unique positionality of bilingual SLTs can yield critical insights to meaningfully address issues of diversity, inclusion and equity in the profession...
March 23, 2024: International Journal of Language & Communication Disorders
https://read.qxmd.com/read/38515565/ferroptosis-in-lung-cancer-dual-role-multi-level-regulation-and-new-therapeutic-strategies
#9
REVIEW
Yunbin Li, Xiaosong Li, Jian Li
Lung cancer is a highly prevalent malignant tumor worldwide, with high incidence and death rates. Recently, there has been increasing recognition of the role of ferroptosis, a unique cell death mechanism, in lung cancer. This review aims to summarize the current research progress on the relationship between ferroptosis and lung cancer. It also provides a comprehensive analysis of the regulatory processes of ferroptosis in various stages, including epigenetics, transcription, post-transcription, translation, and post-translation...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38515384/dietary-supplementation-with-seeds-of-sesamum-indicum-l-pedaliaceae-mitigates-the-7-12-dimethylbenz-a-anthracene-induced-breast-tumor-burden-in-rats
#10
JOURNAL ARTICLE
Eric Beyegue, Florence Afna, Jonas Walantini, Charlotte Mungho Tata, Malla Gambo Abdoulaye, Dieudonné Njamen, Stéphane Zingue, Derek Tantoh Ndinteh
OBJECTIVES: Sesamum indicum L. seeds; rich in zinc and lignans are endowed with antioxidant and immunomodulatory properties which attract research on their anticancer potential. Although many studies have reported the in vitro antitumor potential of S. indicum and its phytoconstituents, much is yet to be known about its in vivo effects. To fill this gap, the effects of dietary supplementation with seeds of S. indicum in 7,12-dimethylbenz(a)anthracene-exposed rats was assessed...
March 25, 2024: Journal of Complementary & Integrative Medicine
https://read.qxmd.com/read/38515382/fetal-protective-effect-of-indonesian-propolis-from-apis-mellifera-against-rifampicin-pyrazinamide-induced-impaired-pregnancy-in-balb-c-mice
#11
JOURNAL ARTICLE
Rahmad Abdillah, Fitri Rachmaini, Dinda Fadhilah, Almahdy Almahdy
OBJECTIVE: Anti-tuberculosis drugs Rifampicin and Pyrazinamide combination in pregnancy can cause morphological, visceral and skeletal damage. Several studies showed that propolis improves pregnancy outcomes. This study aims to determine the fetal protective effect of propolis in BALB/c mice given the anti-tuberculosis drug combination Rifampicin and Pyrazinamide. METHODS: A total of 21 pregnant mice were randomly divided into three groups: the normal group (N) was given distilled water as a vehicle, the positive control group (RP) were given rifampicin 15 mg/kg BW, pyrazinamide 35 mg/kg BW and the treatment group (IP) were given rifampicin 15 mg/kg BB, pyrazinamide 35 mg/kg BW and propolis 400 mg/kg BW...
March 25, 2024: Journal of Complementary & Integrative Medicine
https://read.qxmd.com/read/38514482/state-of-the-art-of-silica-nanoparticles-an-overview-on-biodistribution-and-preclinical-toxicity-studies
#12
REVIEW
Joshua Yu, Nirnoy Dan, Seyyed Majid Eslami, Xiuling Lu
Over the past few years, nanoparticles have drawn particular attention in designing and developing drug delivery systems due to their distinctive advantages like improved pharmacokinetics, reduced toxicity, and specificity. Along with other successful nanosystems, silica nanoparticles (SNPs) have shown promising effects for therapeutic and diagnostic purposes. These nanoparticles are of great significance owing to their modifiable surface with various ligands, tunable particle size, and large surface area. The rate and extent of degradation and clearance of SNPs depend on factors such as size, shape, porosity, and surface modification, which directly lead to varying toxic mechanisms...
March 21, 2024: AAPS Journal
https://read.qxmd.com/read/38514220/telerehabilitation-following-stroke
#13
REVIEW
Steven C Cramer, Brittany M Young, Anne Schwarz, Tracy Y Chang, Michael Su
Stroke remains a major cause of disability. Intensive rehabilitation therapy can improve outcomes, but most patients receive limited doses. Telehealth methods can overcome obstacles to delivering intensive therapy and thereby address this unmet need. A specific example is reviewed in detail, focused on a telerehabilitation system that targets upper extremity motor deficits after stroke. Strengths of this system include provision of daily therapy associated with very high patient compliance, safety and feasibility in the inpatient or home setting, comparable efficacy to dose-matched therapy provided in-clinic, and a holistic approach that includes assessment, education, prevention, and activity-based therapy...
May 2024: Physical Medicine and Rehabilitation Clinics of North America
https://read.qxmd.com/read/38510868/multidisciplinary-management-and-rehabilitation-of-severe-crush-injury-resulting-in-lisfranc-fracture-a-case-report
#14
Radha Nangliya, Sojwal P Nandanwar, Maithili Deshpande
A 58-year-old male patient was seriously injured in his left foot as a result of a passenger car accident, resulting in a Lisfranc fracture and complications on his left side. The initial injury resulted in a 20-cm laceration, severe pain, and severe swelling. After primary care at the government hospital, the patient was referred to Acharya Vinoba Bhave Rural Hospital (AVBRH) for further treatment. Clinical examination revealed infection, Lisfranc ligament rupture, bone exposure, restriction of movement, and muscle strength...
February 2024: Curēus
https://read.qxmd.com/read/38510287/determinants-of-impaired-peak-oxygen-uptake-in-breast-cancer-survivors-jacc-%C3%A2-cardiooncology-primer
#15
REVIEW
Stephen J Foulkes, Mark J Haykowsky, Todd Li, Jing Wang, Megan Kennedy, Amy A Kirkham, Richard B Thompson, D Ian Paterson, Andre La Gerche, Edith Pituskin
•Exercise intolerance is common among breast cancer survivors.•Exercise intolerance in breast cancer survivors is related to cardiac, vascular, and skeletal muscle impairments.•Holistic rehabilitation or pharmacological therapies are needed to address these impairments.
February 2024: JACC CardioOncology
https://read.qxmd.com/read/38507608/clinical-pharmacist-counselling-improves-long-term-medication-safety-and-patient-reported-outcomes-in-anti-tnf-treated-patients-with-inflammatory-bowel-diseases-the-prospective-randomized-adphanced-trial
#16
JOURNAL ARTICLE
Johannes Plechschmidt, Konstantin Fietkau, Tobias Hepp, Peter Dietrich, Sarah Fischer, Sabine Krebs, Markus F Neurath, Frank Dörje, Raja Atreya
BACKGROUND: Antitumor necrosis factor (anti-TNF) antibody treatment has led to marked improvements in the management of patients with inflammatory bowel diseases (IBDs). Nevertheless, anti-TNF therapy is associated with potential adverse drug reactions (ADRs). Our prospective, randomized trial investigated the effect of intensified clinical pharmacist counselling in a multidisciplinary team on medication safety in anti-TNF-treated IBD patients. METHODS: Patients with IBD with ongoing anti-TNF treatment were enrolled in our tertiary center AdPhaNCED trial and randomized to either receive conventional standard of care (control group) or additional clinical pharmacist counselling (intervention group) over 12 months...
March 20, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38506632/examining-the-early-academic-performance-of-doctor-of-physical-therapy-students-after-holistic-review-a-retrospective-cohort-study
#17
JOURNAL ARTICLE
Megan Eikenberry
INTRODUCTION: A diverse health care workforce can help to address systemic health disparities. Holistic review and use of an expanded definition of underrepresented minority (URM) that includes factors beyond race and ethnicity are suggested methods to promote diversity in the physical therapist (PT) workforce and ultimately address societal health disparities. REVIEW OF LITERATURE: Evidence suggests that holistic review can promote PT student diversity; however, limited evidence exists that describes the academic outcomes of holistic review that consider social determinants of learning (SDOL) factors in the review process...
March 19, 2024: Journal, Physical Therapy Education
https://read.qxmd.com/read/38505556/metabolites-a-converging-node-of-host-and-microbe-to-explain-meta-organism
#18
REVIEW
Nabarun Chakraborty
Meta-organisms encompassing the host and resident microbiota play a significant role in combatting diseases and responding to stress. Hence, there is growing traction to build a knowledge base about this ecosystem, particularly to characterize the bidirectional relationship between the host and microbiota. In this context, metabolomics has emerged as the major converging node of this entire ecosystem. Systematic comprehension of this resourceful omics component can elucidate the organism-specific response trajectory and the communication grid across the ecosystem embodying meta-organisms...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38505332/roux-en-y-gastric-bypass-in-a-transgender-patient-a-case-report
#19
Rahul Menon, Phil Lockie
The frequency of transgender individuals seeking gender affirming care is increasing over the last decade. Transgender patients suffer from obesity and psychiatric illness at elevated levels compared with the general population. A 54-year-old male-to-female transition patient presented with morbid obesity, hyperlipidaemia, and weight gain 2 years after their gender-transition and hormonal therapy. She received a Roux-en-Y gastric bypass (RYGB). At 7 months postoperatively, the patient has experienced 49% excess body weight loss, her body dissatisfaction had resolved and has completed further plastic surgery...
March 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38503613/efficacy-and-safety-of-tongxin-formula-after-stent-implantation-for-acute-coronary-syndrome-a-multicenter-double-blind-placebo-controlled-randomized-trial
#20
JOURNAL ARTICLE
Wen Zhu, Su Wang, Lei Zhang, Feng-Qun Xie, Jie Cheng, Xian-Kai Li, Wei Chen, Shi-Yun Yan, Qi-Mao Feng
OBJECTIVE: The aim of this study is to comprehensively evaluate both the efficacy and safety profile of integrating the Tongxin formula with optimal medical therapy (OMT) for patients experiencing acute coronary syndromes subsequent to coronary stenting, over the course of one year. METHODS: We enrolled 150 patients diagnosed with acute coronary syndromes who had received stent placement within one month and exhibited a TCM syndrome characterized by Qi deficiency and blood stasis...
March 1, 2024: Explore: the Journal of Science and Healing
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