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https://read.qxmd.com/read/30782120/frailty-an-in-depth-qualitative-study-exploring-the-views-of-community-care-staff
#1
J F Coker, M E Martin, R M Simpson, L Lafortune
BACKGROUND: Frailty is seen across various health and social care settings. However, little is known about how healthcare professionals, particularly those who provide care for older adults living in the community view frailty. There is also a dearth of information about the extent to which a shared understanding of frailty exists across the various disciplines of care. Such an understanding is crucial across care professionals as it ensures consistent assessment of frailty and facilitates interdisciplinary working/collaboration which is a key component in the management of frailty...
February 19, 2019: BMC Geriatrics
https://read.qxmd.com/read/30777255/implementing-workshops-to-improve-radiation-therapists-knowledge-and-attitudes-about-sexual-health-issues-in-cancer-patients
#2
Carina Feuz, Karen Tse, Maisie Kwan, Christine Hill, Peter Rakaric, Kieng Tan, Tara Rosewall
OBJECTIVES: Although it is widely acknowledged that radiotherapy treatments can have a negative impact on a patient's sexual health, this aspect of side effect management is not commonly addressed by radiation therapists or by other cancer specialists. It is important for radiation therapists to recognize and address possible sexual health issues to provide a holistic approach to care. This quality-improvement project was designed to help radiation therapists discuss the sexual health needs of patients undergoing radiotherapy by improving their clinical knowledge, skills, and comfort level about the topic...
March 2019: Journal of Medical Imaging and Radiation Sciences
https://read.qxmd.com/read/30777240/evolution-of-the-radiation-therapist-role-in-a-multidisciplinary-palliative-radiation-oncology-clinic
#3
Bronwen LeGuerrier, Fleur Huang, Winter Spence, Brenda Rose, Jacqueline Middleton, Megan Palen, Kitta Thvone, Shazma Ravji, Brita Danielson, Diane Severin, Karen P Chu, Alysa Fairchild
BACKGROUND: Palliative radiation therapists (PRTs) have been integrated in varying capacities into outpatient palliative radiation therapy (RT) services across Canada for over 2 decades. At our institution, PRTs have developed an essential role over 11 years within a palliative radiation oncology (PRO) clinic that focuses on integrating symptom management with radiation oncology assessment for palliative RT. PRTs have had direct clinical, technical, research, and administrative involvement as the clinic evolved from a pilot in 2007 supporting one half-day per week to the current model of five full clinical days...
March 2019: Journal of Medical Imaging and Radiation Sciences
https://read.qxmd.com/read/30775378/prevalence-of-depression-and-associated-factors-among-diabetic-patients-in-an-outpatient-diabetes-clinic
#4
Zahra D Khan, Janet Lutale, Sibtain M Moledina
Despite adequate treatment for diabetes, it is estimated that 15%- 20% of people with diabetes are struggling with a moderate to severe form of depression daily. Little is known about depression in diabetes in East Africa, particularly in Tanzania. The study is aimed at determining the prevalence of depression and associated factors among patients with diabetes. A descriptive cross-sectional study was carried out at the diabetes clinic of Muhimbili National Hospital. The 9-item Patient Health Questionnaire (PHQ 9) scale was used to assess presence of depressive symptoms among diabetes patients at the clinic...
2019: Psychiatry Journal
https://read.qxmd.com/read/30773868/-progress-of-researches-on-acupuncture-treatment-of-diseases-by-regulating-endoplasmic-reticulum-stress
#5
Hua Zhao, Jie Jiang
Endoplasmic reticulum stress (ERS) is one of the major defense networks in mammals, but continuous ERS will lead to cell apoptosis, inducing initiation and progression of many human diseases. Biochemical, physiological and pathological stimuli induced ERS may help the cells adapt to and survive stress conditions by activating unfolded protein response (UPR), ER-overload response and sterol modulation cascade reaction. Abundant outcomes of clinical and experimental studies in recent 5 years showed that acupuncture and moxibustion therapies are effective in improving some symptoms of nervous system diseases as stroke, Parkinson's disease, convulsion, cardiovascular diseases, diabetes mellitus, non-alcoholic fatty liver disease, spinal cord injury, muscular injury, etc...
January 25, 2019: Zhen Ci Yan Jiu, Acupuncture Research
https://read.qxmd.com/read/30765321/repetitive-voice-evaluation-in-dysphonic-teachers-office-versus-home
#6
Batoul Jaber, Reina Remman, Nayla Matar
INTRODUCTION: A patient's voice can vary from one moment to another, and these variations cannot be captured by a one-time assessment. Multiple assessments may give a more holistic idea of the severity of the patient's dysphonia and by asking the patient to do the recordings he becomes involved in his therapeutic plan from the beginning. AIM: This study aims to evaluate the added value of a repetitive assessment outside the speech therapist's (SLP) clinic, to have a broader vision of the voice disorder and identify parameters that change after working hours to be able to explain this disorder and find solutions for it...
February 11, 2019: Journal of Voice: Official Journal of the Voice Foundation
https://read.qxmd.com/read/30763390/highly-efficient-and-sensitive-patient-specific-quality-assurance-for-spot-scanned-proton-therapy
#7
J E Johnson, C Beltran, H Wan Chan Tseung, D W Mundy, J J Kruse, T J Whitaker, M G Herman, K M Furutani
The purpose of this work was to develop an end-to-end patient-specific quality assurance (QA) technique for spot-scanned proton therapy that is more sensitive and efficient than traditional approaches. The patient-specific methodology relies on independently verifying the accuracy of the delivered proton fluence and the dose calculation in the heterogeneous patient volume. A Monte Carlo dose calculation engine, which was developed in-house, recalculates a planned dose distribution on the patient CT data set to verify the dose distribution represented by the treatment planning system...
2019: PloS One
https://read.qxmd.com/read/30762716/headaches-in-idiopathic-intracranial-hypertension
#8
Deborah I Friedman
BACKGROUND: Headache is the most common symptom of idiopathic intracranial hypertension (IIH) and may not resolve with intracranial pressure-lowering treatments. Many patients with IIH have a pre-existing history of migraine. Approximately two-thirds of patients with IIH continue to experience headaches after the other manifestations of the disorder resolve. There are no evidence-based guidelines for treating IIH-related headaches. EVIDENCE ACQUISITION: This review proposes mechanisms by which IIH produces both acute and ongoing headache...
March 2019: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://read.qxmd.com/read/30747777/nurses-and-holistic-modalities-the-history-of-chinese-medicine-and-acupuncture
#9
Carol Chunfeng Wang, Ruifang Zhu, Jing-Yu Tan
Holistic nursing practices holism and holistic modalities to create a healing space and optimize the healing process. Holistic nurses employ a complementary and integrative focus in their work and help patients access their greatest healing potential. This article supports that nursing professionals embrace acupuncture and alternative therapy as a great gift that inspire them to extend their already extraordinary healing power. An overview of the history of Traditional Chinese Medicine and the development and milestones of acupuncture and moxibustion in past dynasties is presented...
March 2019: Holistic Nursing Practice
https://read.qxmd.com/read/30747734/cryptic-conspirators-a-conversation-about-thrombocytopenia-and-antiphospholipid-syndrome
#10
Andrew P Vreede, Paula L Bockenstedt, W Joseph McCune, Jason S Knight
PURPOSE OF REVIEW: Although antiphospholipid syndrome (APS) is best known for conveying increased risk of thrombotic events and pregnancy morbidity, thrombocytopenia is also recognized as a common association. In this review, we will explore the relationship between thrombocytopenia and APS, highlighting our evolving understanding - and persistent knowledge gaps - through clinically oriented questions and answers. RECENT FINDINGS: A history of thrombocytopenia likely portends a more severe APS phenotype (including increased risk of thrombosis)...
February 11, 2019: Current Opinion in Rheumatology
https://read.qxmd.com/read/30746989/breathlessness-in-palliative-care-a-practical-guide
#11
Suzie Gillon, Ian J Clifton
Breathlessness is a common symptom for patients with terminal illness and can be challenging to manage. Breathlessness is acknowledged to be an interaction between body and mind. There are a variety of pharmacological and non-pharmacological therapies that can be beneficial. The holistic assessment of the breathlessness patient should enable delivery of a tailored package of care focused on relief of symptoms.
February 2, 2019: British Journal of Hospital Medicine
https://read.qxmd.com/read/30744689/the-role-and-mechanisms-of-action-of-micrornas-in-cancer-drug-resistance
#12
REVIEW
Wengong Si, Jiaying Shen, Huilin Zheng, Weimin Fan
MicroRNAs (miRNAs) are small non-coding RNAs with a length of about 19-25 nt, which can regulate various target genes and are thus involved in the regulation of a variety of biological and pathological processes, including the formation and development of cancer. Drug resistance in cancer chemotherapy is one of the main obstacles to curing this malignant disease. Statistical data indicate that over 90% of the mortality of patients with cancer is related to drug resistance. Drug resistance of cancer chemotherapy can be caused by many mechanisms, such as decreased antitumor drug uptake, modified drug targets, altered cell cycle checkpoints, or increased DNA damage repair, among others...
February 11, 2019: Clinical Epigenetics
https://read.qxmd.com/read/30741032/a-qualitative-study-of-loveyourbrain-yoga-a-group-based-yoga-with-psychoeducation-intervention-to-facilitate-community-integration-for-people-with-traumatic-brain-injury-and-their-caregivers
#13
Kyla Z Donnelly, Shari Goldberg, Debra Fournier
PURPOSE: To explore participants' experiences in a group-based yoga with psychoeducation intervention designed to facilitate community integration for people with traumatic brain injury and their caregivers. MATERIALS AND METHODS: We conducted semi-structured interviews with 13 people with traumatic brain injury and three caregivers who had completed LoveYourBrain Yoga, a 6-session, manualized, group-based yoga intervention that incorporates breathing exercises, yoga, meditation, and psychoeducation...
February 11, 2019: Disability and Rehabilitation
https://read.qxmd.com/read/30738856/lung-transplantation-for-idiopathic-pulmonary-fibrosis
#14
REVIEW
Peter M George, Caroline M Patterson, Anna K Reed, Muhunthan Thillai
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis. Lung transplantation is the only intervention shown to increase life expectancy for patients with IPF, but it is associated with disease-specific challenges. In this Review, we discuss the importance of a proactive approach to the management of IPF comorbidities, including gastro-oesophageal reflux, pulmonary hypertension, coronary artery disease, and malignancy. With a donor pool too small to meet demand and unacceptably high mortality on transplant waiting lists, we discuss different systems used internationally to facilitate organ allocation...
February 6, 2019: Lancet Respiratory Medicine
https://read.qxmd.com/read/30735954/microtubule-network-as-a-potential-candidate-for-targeting-by-gold-nanoparticle-assisted-photothermal-therapy
#15
Behafarid Ghalandari, Kazem Asadollahi, Ali Shakerizadeh, Ali Komeili, Gholamhossein Riazi, Seyed Kamran Kamrava, Neda Attaran
Photothermal therapy is achieving ever-increasing attention as a promising method for killing cancer cells. Although, gold nanoparticles are regarded as one of the most effective photothermal therapy agents, the mechanisms underlying their action have to be addressed. Moreover, studies have showed that gold nanoparticles induce apoptosis in treated cultures. Hence, in this study, we investigated the interaction of folic acid functionalized gold nanoparticles and gold-shelled Fe3 O4 nanoparticles with microtubule and microtubule associated protein tau in order to introduce intracellular targets of these nanoparticles and provide a holistic view about the mechanism of action of gold nanoparticles used in photothermal therapy...
January 31, 2019: Journal of Photochemistry and Photobiology. B, Biology
https://read.qxmd.com/read/30714983/impact-of-yoga-based-mind-body-intervention-on-systemic-inflammatory-markers-and-co-morbid-depression-in-active-rheumatoid-arthritis-patients-a-randomized-controlled-trial
#16
Surabhi Gautam, Madhuri Tolahunase, Uma Kumar, Rima Dada
BACKGROUND: Recovery of the patients with rheumatoid arthritis (RA) depends on several physical and psychological factors, besides pharmacological treatment. Co-morbid depression adversely affects the outcome in RA. Usual medical therapies have a limited scope and fail to cure the psychological component of the disease. With advanced therapeutic options, achieving a state of remission has become the treatment goal, yoga based mind body intervention (MBI) may provide a holistic approach to its treatment dimension...
February 1, 2019: Restorative Neurology and Neuroscience
https://read.qxmd.com/read/30701635/when-does-organic-photoredox-catalysis-meet-artificial-photosynthesis
#17
EDITORIAL
Erwin Reisner
"Although the same basics of photocatalysis unite applications in artificial photosynthesis, photoreformation, photoredox catalysis and photodynamic therapy, they are being developed in surprising isolation. … This editorial is a call to join forces and embrace progress in all of these areas to enable accelerated development of a more holistic science in photocatalysis. …" Read more in the Guest Editorial by E. Reisner.
January 31, 2019: Angewandte Chemie
https://read.qxmd.com/read/30697355/using-pharmacogenetic-testing-or-platelet-reactivity-testing-to-tailor-antiplatelet-therapy-are-asians-different-from-caucasians
#18
REVIEW
Doreen Tan Su-Yin
All studies to date involving platelet reactivity and gene testing document singular interventions and their associations with outcomes. The East Asian paradox has been well documented - Asians who have had a percutaneous coronary intervention (PCI) are at a lower risk of ischaemic events even though they have a higher platelet reactivity. Asians who have had a PCI also have a higher risk of bleeding. This article covers the differences in outcomes between Caucasians and Asians, and explores the impact of outcomes, highlighting differences between the two patient populations...
December 2018: European Cardiology
https://read.qxmd.com/read/30691282/dying-well-with-diabetes
#19
June James
Death is an inevitable part of living. There are undoubtedly clinical and psychological challenges when any individual is passing from life to death. For a person with a long-term condition such as diabetes, these challenges can be compounded and impact on the care and experience of both the individual and their families and carers. It is estimated that about 500,000 people die each year in the United Kingdom; of these approximately 75,000 will have diabetes. The vast majority of people with diabetes who die do not do so as a result of a metabolic diabetes emergency such as diabetic ketoacidosis or hyperosmolar hyperglycaemic state...
January 17, 2019: Annals of Palliative Medicine
https://read.qxmd.com/read/30679089/inclusion-and-perception-of-hand-therapy-content-in-occupational-therapy-programs-a-mixed-method-study
#20
Nathan Short, Jennifer Bain, Courtney Barker, Kristina Dammeyer, Ethan Fahrney, Kalin Hale, Caitlyn Nieman
STUDY DESIGN: Mixed-methods with cross-sectional survey and interviews. INTRODUCTION: Hand therapy is a specialty area of practice for occupational (OT) and physical therapists (PT), requiring experience and certification beyond entry-level generalist education. Perspectives and inclusion of content related to hand therapy differs among entry-level OT programs and faculty. PURPOSE: Perception and inclusion of hand therapy content in OT programs was examined in this mixed-method study to better understand the trends in academia regarding integration of content related to hand therapy...
January 21, 2019: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
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