keyword
https://read.qxmd.com/read/38272284/intrapartum-cardiotocography-with-simultaneous-maternal-heart-rate-registration-improves-neonatal-outcome
#21
JOURNAL ARTICLE
Mikko Tarvonen, Janne Markkanen, Ville Tuppurainen, Riina Jernman, Vedran Stefanovic, Sture Andersson
BACKGROUND: Intrapartum cardiotocographic monitoring of fetal heart rate by abdominal external ultrasound transducer without simultaneous maternal heart rate recording has been associated with increased risk of early neonatal death and other asphyxia-related neonatal outcomes. It is unclear, however, whether this increase in risk is independently associated with fetal surveillance method or is attributable to other factors. OBJECTIVES: In a large retrospective cohort of deliveries, the aim of the present study was to compare different fetal surveillance methods and their association with adverse short-term and long-term fetal and neonatal outcomes...
January 21, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38266914/predicting-environmental-concentrations-of-nanomaterials-for-exposure-assessment-a-review
#22
JOURNAL ARTICLE
Arturo A Keller, Yuanfang Zheng, Antonia Praetorius, Joris T K Quik, Bernd Nowack
There have been major advances in the science to predict the likely environmental concentrations of nanomaterials, which is a key component of exposure and subsequent risk assessment. Considerable progress has been since the first Material Flow Analyses (MFAs) in 2008, which were based on very limited information to more refined current tools that take into account engineered nanoparticle (ENP) size distribution, form, dynamic release, and better-informed release factors. These MFAs provide input for all environmental fate models (EFMs), that generate estimates of mass flows and concentrations in various environmental compartments...
January 22, 2024: NanoImpact
https://read.qxmd.com/read/38259246/elucidating-the-role-of-diverse-mineralisation-paradigms-on-bone-biomechanics-a-coarse-grained-molecular-dynamics-investigation
#23
JOURNAL ARTICLE
Mahdi Tavakol, Ted J Vaughan
Bone as a hierarchical composite structure plays a myriad of roles in vertebrate skeletons including providing the structural stability of the body. Despite this critical role, the mechanical behaviour at the sub-micron levels of bone's hierarchy remains poorly understood. At this scale, bone is composed of Mineralised Collagen Fibrils (MCF) embedded within an extra-fibrillar matrix that consists of hydroxyapatite minerals and non-collagenous proteins. Recent experimental studies hint at the significance of the extra-fibrillar matrix in providing the bone with the stiffness and ductility needed to serve its structural roles...
January 23, 2024: Nanoscale
https://read.qxmd.com/read/38256403/effect-of-pethidine-injection-on-the-duration-of-labor-and-pregnancy-outcomes-a-retrospective-cohort-study
#24
JOURNAL ARTICLE
Eun Byeol Cho, Hyun Joo Chae, Jung Min Ryu, Hyo Jin Lee, Seong Yeon Hong, Jin Young Bae
Background and Objectives : Long and ineffective labor causes hardships for mothers and doctors and increases the rate of cesarean sections and medical comorbidities. Several factors contribute to effective and less painful labor, including maternal age, parity, fetal characteristics, and the medications or procedures that obstetricians use for labor. We aimed to study the factors that affect labor duration and identify those that make labor more effective. Materials and Methods : This retrospective study included 141 patients who underwent normal vaginal deliveries at the Daegu Catholic University Medical Center between April 2013 and April 2022...
January 12, 2024: Medicina
https://read.qxmd.com/read/38253982/the-correlation-between-the-total-decelerations-and-accelerations-areas-and-cord-blood-ph-in-women-with-low-risk-pregnancies
#25
JOURNAL ARTICLE
Noam Shema, Adi Y Weintraub, Reut Rotem, Shimrit Yaniv Salem
Fetal acidosis among low-risk pregnancies is not common; however, identifying those at risk for this complication antenatally is of great interest. We aimed to assess the correlation between the total decelerations area during the last 120 min of fetal monitoring prior to delivery and neonatal acidemia in low-risk pregnancies and whether the total acceleration area has a protective effect in the presence of decelerations. A retrospective cohort study was conducted among women with term low-risk pregnancies...
January 22, 2024: Reproductive Sciences
https://read.qxmd.com/read/38247950/data-driven-insights-into-labor-progression-with-gaussian-processes
#26
JOURNAL ARTICLE
Tilekbek Zhoroev, Emily F Hamilton, Philip A Warrick
Clinicians routinely perform pelvic examinations to assess the progress of labor. Clinical guidelines to interpret these examinations, using time-based models of cervical dilation, are not always followed and have not contributed to reducing cesarean-section rates. We present a novel Gaussian process model of labor progress, suitable for real-time use, that predicts cervical dilation and fetal station based on clinically relevant predictors available from the pelvic exam and cardiotocography. We show that the model is more accurate than a statistical approach using a mixed-effects model...
January 11, 2024: Bioengineering
https://read.qxmd.com/read/38242584/intrapartum-electronic-fetal-monitoring-imperfect-technologies-and-clinical-uncertainties-what-can-a-human-factors-and-social-science-approach-add
#27
EDITORIAL
Jane Sandall
No abstract text is available yet for this article.
January 19, 2024: BMJ Quality & Safety
https://read.qxmd.com/read/38237311/correlation-between-intrapartum-ctg-findings-and-interleukin-6-levels-in-the-umbilical-cord-arterial-blood-a-prospective-cohort-study
#28
JOURNAL ARTICLE
Elvira di Pasquo, Stefania Fieni, Edwin Chandraharan, Andrea Dall'Asta, Giovanni Morganelli, Marta Spinelli, Maria Laura Bettinelli, Rosalia Aloe, Annalisa Russo, Letizia Galli, Serafina Perrone, Tullio Ghi
OBJECTIVE: to investigate the correlation between the intrapartum CardioTocoGraphic (CTG) findings "suggestive of fetal inflammation" ("SOFI") and the interleukin (IL)-6 level in the umbilical arterial blood. STUDY DESIGN: prospective cohort study conducted at a tertiary maternity unit and including 447 neonates born at term. METHODS: IL-6 levels were systematically measured at birth from a sample of blood taken from the umbilical artery. The intrapartum CTG traces were retrospectively reviewed by two experts who were blinded to the postnatal umbilical arterial IL-6 values as well as to the neonatal outcomes...
January 13, 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38237206/in-silico-simulation-of-nanoindentation-on-bone-using-a-2d-cohesive-finite-element-model
#29
JOURNAL ARTICLE
Pengwei Xiao, Anuradha Roy, Xiaodu Wang
This study proposed and validated a 2D finite element (FE) model for conducting in-silico simulations of in-situ nanoindentation tests on mineralized collagen fibrils (MCF) and the extrafibrillar matrix (EFM) within human cortical bone. Initially, a multiscale cohesive FE model was developed by adapting a previous model of bone lamellae, encompassing both MCF and EFM. Subsequently, nanoindentation tests were simulated in-silico using this model, and the resulting predictions were compared to AFM nanoindentation test data to verify the model's accuracy...
January 12, 2024: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/38236606/imaging-the-quantum-capacitance-of-strained-mos-2-monolayers-by-electrostatic-force-microscopy
#30
JOURNAL ARTICLE
Cinzia Di Giorgio, Elena Blundo, Julien Basset, Giorgio Pettinari, Marco Felici, Charis H L Quay, Stanislas Rohart, Antonio Polimeni, Fabrizio Bobba, Marco Aprili
We implemented radio frequency-assisted electrostatic force microscopy (RF-EFM) to investigate the electric field response of biaxially strained molybdenum disulfide (MoS2 ) monolayers (MLs) in the form of mesoscopic bubbles, produced via hydrogen (H)-ion irradiation of the bulk crystal. MoS2 ML, a semiconducting transition metal dichalcogenide, has recently attracted significant attention due to its promising optoelectronic properties, further tunable by strain. Here, we take advantage of the RF excitation to distinguish the intrinsic quantum capacitance of the strained ML from that due to atomic scale defects, presumably sulfur vacancies or H-passivated sulfur vacancies...
January 18, 2024: ACS Nano
https://read.qxmd.com/read/38230937/whole-genome-long-read-sequencing-to-unveil-enterococcus-antimicrobial-resistance-in-dairy-cattle-farms-exposed-a-widespread-occurrence-of-enterococcus-lactis
#31
JOURNAL ARTICLE
Medelin Ocejo, Maitane Mugica, Beatriz Oporto, José Luis Lavín, Ana Hurtado
Enterococcus species identification is crucial due to differences in pathogenicity and antibiotic resistance profiles. The failure of traditional methods or whole-genome sequencing-based taxonomic classifiers to distinguish Enterococcus lactis ( Elc ) from Enterococcus faecium ( Efm ) results in a biased interpretation of Efm epidemiology. The Efm species-specific real-time PCR assay developed here will help to properly identify Efm (only the formerly known clade A) in future studies. Here, we showed that Elc is prevalent in dairy cattle, and although this species carries fewer genetic determinants of resistance (GDRs) than Enterococcus faecalis ( Efs ) and Efm , it can carry multi-drug-resistant (MDR) plasmids and could act as a donor of resistance genes for other pathogenic enterococcal species...
January 17, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38230384/the-importance-of-fetoplacental-doppler-velocimetry-for-fetal-surveillance-during-general-anesthesia-for-non-obstetric-surgery
#32
Silvio Tartaglia, Bruno A Zanfini, Salvatore Gueli Alletti, Gaetano Draisci, Antonio Lanzone
Fetal heart rate monitoring during general anesthesia for non-obstetric surgery at viable gestational ages is recommended to evaluate fetal well-being during the intervention. Alteration induced by anesthetic drugs could mimic fetal acute hypoxia, leading to pointless Cesarean sections. We report a case of a pregnant woman in the third trimester undergoing neurosurgical surgery. The continuous heart rate registration showed a non-reassuring pattern, potentially inducing the multidisciplinary team to expedite the delivery...
January 2024: Curēus
https://read.qxmd.com/read/38225432/correlation-between-total-deceleration-area-in-ctg-records-and-cord-blood-ph-in-pregnancies-with-iugr
#33
JOURNAL ARTICLE
Neta Geva, Yael Geva, Lior Katz, Yair Binyamin, Reut Rotem, Adi Yehuda Weintraub, Shimrit Yaniv Salem
PURPOSE: Fetal cardiotocography is the most common method to assess fetal well-being during labor. Nevertheless, its predictive ability for acidemia is limited, both in low-risk and high-risk pregnancies (Nelson et al. in N Engl J Med 334: 613-9, 1996; Rinciples P et al. in Health and Human Development Workshop Report on Electronic Fetal Monitoring : Update on Definitions. no. 2007, 510-515, 2008), especially in high-risk pregnancies, such as those complicated by growth restriction...
January 16, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38196476/hepatitis-c-during-pregnancy-antenatal-period-challenges-management-and-the-way-forward
#34
REVIEW
Lubna Kamani, Asma Abdul Razzak
Pregnant women and the general public are both directly impacted by cirrhosis which is a chronic liver disease. It is also widely known that women who have a history of injectable drug use and cirrhosis are more prone to experience unfavorable consequences that have a negative impact on the health of both the mother and the unborn child. Higher maternal Hepatitis-C Virus (HCV) in pregnancy viral load, length of labor, use of amniocentesis or fetal scalp monitoring and protracted membrane rupture are all the risk of perinatal transmission of HCV in newborns...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38133768/etiology-and-ontogeny-of-cerebral-palsy-implications-for-practice-and-research
#35
REVIEW
Mark I Evans, David W Britt, Lawrence D Devoe
Cerebral palsy (CP) has been recognized as a group of neurologic disorders with varying etiologies and ontogenies. While a percentage of CP cases arises during labor, the expanded use of electronic fetal monitoring (EFM) to include prevention of CP has resulted in decades of vastly increased interventions that have not significantly reduced the incidence of CP for infants born at term in the USA. Litigation alleging that poor obstetrical practice caused CP in most of these affected children has led to contentious arguments regarding the actual etiologies of this condition and often resulted in substantial monetary awards for plaintiffs...
December 22, 2023: Reproductive Sciences
https://read.qxmd.com/read/38115582/a-dephosphorylation-dependent-molecular-switch-for-ft-repression-mediates-flowering-in-arabidopsis
#36
JOURNAL ARTICLE
Yu Zhang, Changmei Hua, Jian Xuan Kiang, Lisha Shen
The reproductive success of flowering plants greatly relies on the precise timing of floral transition, which is finely modulated by a complex network of floral regulators. As a main floral integrator, FLOWERING LOCUS T (FT) is also known as an essential constituent of the florigen that traffics from leaves to shoot apices to induce flowering. FT is specifically transcribed in leaf vascular tissues where its production is suppressed by many flowering repressors, including a MYB transcription factor, EARLY FLOWERING MYB PROTEIN (EFM)...
December 18, 2023: Plant communications
https://read.qxmd.com/read/38106566/retrospective-analysis-of-pregnancy-outcomes-following-external-cephalic-version-for-breech-presentation
#37
JOURNAL ARTICLE
Jun Han, Shuai Wang, Mei Ding
OBJECTIVE: We explored the feasibility and safety of external cephalic version (ECV) for cases of breech presentation. METHODS: We retrospectively analyzed data from 158 singleton pregnant women with breech presentation at 36 weeks gestation, admitted to Guangzhou Hospital of Integrated Traditional and Western Medicine from January 2018 to March 2022. 42 underwent ECV, categorized as the ECV group, while 116 without ECV comprised the control group. Systematic collection and evaluation of pregnancy outcomes were conducted for both groups...
2023: International Journal of Women's Health
https://read.qxmd.com/read/38104394/pregnancy-management-of-ivf-et-pregnancies-in-a-patient-with-classical-21-hydroxylase-deficiency-a-case-report-and-review-of-the-literature
#38
REVIEW
Junxin Yu, Sha Lu, Lingya Fang, Nisile Kakongoma, Wensheng Hu
OBJECTIVE: To report a rare case of a woman with classical 21-hydroxylase deficiency who twice had singleton pregnancies with live births after in vitro fertilization and embryo transfer (IVF-ET). DESIGN: Case report and literature review. PATIENT: A 35-year-old woman with classical 21-hydroxylase deficiency underwent external genital plastic surgery during adolescence and achieved second pregnancy after IVF-ET with long-term glucocorticoid replacement therapy...
December 7, 2023: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38092425/use-of-non-steroidal-anti-inflammatory-drugs-in-pregnancy-and-oligohydramnios-a-review
#39
REVIEW
Valentina D'Ambrosio, Flaminia Vena, Annalisa Scopelliti, Debora D'Aniello, Giovanna Savastano, Roberto Brunelli, Antonella Giancotti
OBJECTIVE: The aim of this review is to evaluate the relationship between the use of non-steroidal anti-inflammatory drugs (NSAIDs) during last trimesters of the pregnancy and the reduction of amniotic fluid. METHODS: Electronic databases were searched (PubMed, Medline, and Scopus). Selection criteria included studies reporting the relationship between oligohydramnios and use of NSAID during pregnancy. We analyzed the median age of women, weeks of pregnancy at the beginning of the drug administration, kind of medication, period of exposure and dosage, deepest vertical pocket (DVP), and amniotic fluid index (AFI)...
December 2023: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38083638/detection-of-twin-pregnancies-using-fetal-phonocardiogram
#40
JOURNAL ARTICLE
Rajeshwari Bs, Aman Sinha, Arnab Sengupta, Dhaladhuli Jahnavi, Nirmalya Ghosh, Amit Patra
Fetal phonocardiogram (fPCG), or the electronic recording of fetal heart sounds, is a safe and easily available signal that can be used to monitor fetal wellbeing. In the proposed work an attempt is made to identify twin pregnancies using fPCG data recorded from the fetus with 1/3rd power in octave band filtered output as features to train K-Nearest Neighbor (KNN) and support vector machine (SVM) classifiers. The SVM classifier with the quadratic kernel is able to identify singletons and twins with a positive predictive value of 100% and 79...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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