Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Iana Aragão Magalhães, Gabriella Alves Juliao Costa, Marcela Maria Fontes Borges, Anna Clara Aragão Matos Carlos, Karine Cestaro Mesquita, Larissa Mont Alverne de Arruda, Maria do Perpétuo Socorro Saldanha Cunha, Fabrício Bitu Sousa, Paulo Goberlânio de Barros Silva
OBJECTIVE: To evaluate the immunoexpression profile for CD8, CD3, CD20 and CD68 in the process and carcinogenesis of Carcinoma of the vermilion lip. METHODS: Average cell count with positive expression for CD3, CD8, CD20 and CD68. The CD8/CD3 ratio calculated in the region was based on the percentage of positive cells in a total of malignant cells. Kruska-Wallis/Dunn, Mann-Whitney and Spearman correlation tests (SPSS, p < 0.05) were used. RESULTS: In the Aquitic Cheilitis samples, there was an increase in intraepithelial CD8+ and CD68+...
December 19, 2023: Brazilian Journal of Otorhinolaryngology
#2
JOURNAL ARTICLE
Juliana Afonso, Andressa Oliveira Lima, Marco Antonio Perpétuo de Sousa, Flávia Regina Florêncio de Athayde, Marina Rufino Salinas Fortes
Spermatogenesis is highly conserved among mammalians, but its gene expression and regulatory profile are not entirely known. As transcription factors (TFs) and miRNAs are crucial for gene expression regulation, identifying genes negatively regulated by miRNAs and positively regulated by TFs in the testis and epididymis can provide a deeper understanding of gene expression and regulatory patterns. To do this, we used expression data coming from RNA-Seq and miRNA-Seq experiments made with biopsies from testicular parenchyma, head of the epididymis, and tail of the epididymis of four Brahman bulls...
January 3, 2024: Gene
#3
JOURNAL ARTICLE
Comprehensive characterization of protein modifications using mass spectrometry and dry blood spots.
Sofia Guedes, Luís Perpétuo, Jacinta Veloso, Tânia Lima, Ana F Ferreira, Inês Pires, Francisca Savaiva, André Lourenço, Liliana Moreira-Costa, Adelino Leite-Moreira, Antonio Barros, Fábio Trindade, Rui Vitorino
PURPOSE: The main objective of this study is to characterize and analyze modified peptides in DBS samples. This includes deciphering their specific PTMs and understanding their potential impact on the population or disease cohort under study. EXPERIMENTAL DESIGN: Using mass spectrometry-based proteomic approaches, we performed a comprehensive analysis of DBS samples. Our focus was on the identification and quantification of modified peptides. We also took advantage of recent advances in DBS mass spectrometry to ensure accurate detection and quantification...
January 2, 2024: Proteomics. Clinical Applications
#4
JOURNAL ARTICLE
Maria Perpétuo Socorro Sampaio Carvalho, Fábio Magalhães-Gama, Bruna Pires Loiola, Juliana Costa Ferreira Neves, Nilberto Dias Araújo, Flavio Souza Silva, Claudio Lucas Santos Catão, Eliana Brasil Alves, João Paulo Diniz Pimentel, Maria Nazaré Saunier Barbosa, Nelson Abrahim Fraiji, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Allyson Guimarães Costa, Adriana Malheiro
BACKGROUND: Children with B-cell acute lymphoblastic leukemia (B-ALL) have an immune imbalance that is marked by remodeling of the hematopoietic compartment, with effects on peripheral blood (PB). Although the bone marrow (BM) is the main maintenance site of malignancy, the frequency with which immune cells and molecules can be monitored is limited, thus the identification of biomarkers in PB becomes an alternative for monitoring the evolution of the disease. METHODS: Here, we characterize the systemic immunological profile in children undergoing treatment for B-ALL, and evaluate the performance of cell populations, chemokines and cytokines as potential biomarkers during clinical follow-up...
2023: Frontiers in Oncology
#5
JOURNAL ARTICLE
Darci Francisco Dos Santos Junior, Marina Nolli Bittencourt, Priscila Maria Marcheti, José Luís da Cunha Pena, Suellen Cristina da Silva Chaves, Angélica Martins de Souza Gonçalves, Alessandra Matheus Domingos, Maria do Perpétuo do Socorro de Sousa Nóbrega
OBJECTIVE: To assess the relationship between psychopathological symptoms and the social, clinical, and occupational profile of nurses in the Amazon region of Brazil during the COVID-19 pandemic. METHODS: A descriptive cross-sectional online study was conducted in 2020 with 261 nurses. The Symptom Assessment Scale-40 was utilized. RESULTS: The presence of pre-existing conditions before the pandemic was associated with psychotism (p=0.044)...
2023: Revista Brasileira de Enfermagem
#6
JOURNAL ARTICLE
Rosa Correa Leoncio de Sa, Aron Jose Pazin de Andrade, Vagner Roberto Antunes, Cecilia Salvadori, Fernanda de Sa Teixeira, Evaldo Jose Corat, Joao Roberto Moro, Eduardo Guy Perpetuo Bock, Vladimir Jesus Trava-Airoldi
BACKGROUND: The reactivity of blood with non-endothelial surface is a challenge for long-term Ventricular Assist Devices development, usually made with pure titanium, which despite of being inert, low density and high mechanical resistance it does not avoid the thrombogenic responses. Here we tested a modification on the titanium surface with Laser Induced Periodic Surface Structures followed by Diamond Like Carbon (DLC) coating in different thicknesses to customize the wettability profile by changing the surface energy of the titanium...
November 28, 2023: Artificial Organs
#7
JOURNAL ARTICLE
Carla Sílvia Fernandes, Maria Joana Campos, Andreia Novo Lima, Suellen Cristina da Silva Chaves, Eliana Cristina Dos Santos, Dárcio Tadeu Mendes, Maria do Perpétuo Socorro Sousa Nóbrega
OBJECTIVE: To map existing studies on the development of games for refugees, identifying the developed games, characteristics and possible application to health care. METHOD: A scoping review study, carried out in July 2022, using the MEDLINE® (Medical Literature Analysis and Retrieval System Online), CINAHL® (Cumulative Index to Nursing and Allied Health Literature), SPORTDiscus, Scopus, SciELO (Scientific Electronic Library Online), Psychology and Behavioral Sciences Collection, Cochrane Central Register of Controlled Trials databases...
2023: Revista da Escola de Enfermagem da U S P
#8
JOURNAL ARTICLE
Ariane Tufaile Paiva, Flávio Adriano Borges, Pablo Ramon Carloni, Walkiria Jéssica de Araújo Silveira, Márcia Niituma Ogata, Maria do Perpétuo Socorro de Sousa Nóbrega, Luciano Garcia Lourenção, Guadalupe Calvo García
OBJECTIVE: To analyze the role of Family Health Strategy (FHS) nurses in the health care of LGBT+ individuals. METHODS: This qualitative study is based on Institutional Analysis. Data was collected in August 2021 through semi-structured interviews with 14 Family Health Strategy nurses from municipalities in the state of São Paulo. The data was processed using the IRaMuTeQ® software and analyzed lexically. RESULTS: The textual corpus gave rise to three themes, which addressed the nurses' practice, the difficulties and challenges they face in providing care to LGBT+ individuals, and the direct association of LGBT+ individuals with sexually transmitted infections...
2023: Revista Brasileira de Enfermagem
#9
JOURNAL ARTICLE
Emilia Roy-Vallejo, Sara Fernández De Córdoba-Oñate, Pablo Delgado-Wicke, Ana Triguero-Martínez, Nuria Montes, Rosa Carracedo-Rodríguez, Nelly Zurita-Cruz, Ana Marcos-Jiménez, Amalia Lamana, José María Galván-Román, Gonzalo Villapalos García, Pablo Zubiaur, Marianela Ciudad, Laura Rabes, Marta Sanz, Carlos Rodríguez, Almudena Villa, Jesús Álvarez Rodríguez, Celeste Marcos, Julia Hernando, Paula Díaz-Fernández, Francisco Abad, Ignacio de Los Santos, Diego A Rodríguez Serrano, Rosario García-Vicuña, Carmen Suárez Fernández, Rosa P Gomariz, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Isidoro González-Álvaro, Laura Cardeñoso, Ana Barrios, Jesús Sanz, Pedro Casado, Ángela Gutiérrez, Azucena Bautista, Pilar Hernández, Nuria Ruiz Giménez, Berta Moyano, Paloma Gil, María Jesús Delgado, Pedro Parra, Beatriz Sánchez, Carmen Sáez, Marta Fernández Rico, Cristina Arévalo Román, Santos Castañeda, Irene Llorente, Eva G Tomero, Noelia García Castañeda, Miren Uriarte, Leticia Fontán García-Rodrigo, Diego Domingo García, Teresa Alarcón Cavero, María Auxiliadora Semiglia Chong, Ainhoa Gutiérrez Cobos, Francisco Sánchez-Madrid, Enrique Martín Gayo, Ildefonso Sánchez-Cerrillo, Pedro Martínez-Fleta, Celia López-Sanz, Ligia Gabrie, Luciana Del Campo Guerola, Reyes Tejedor, Julio Ancochea, Elena García Castillo, Elena Ávalos, Ana Sánchez-Azofra, Tamara Alonso, Carolina Cisneros, Claudia Valenzuela, Francisco Javier García Pérez, Rosa María Girón, Javier Aspa, Celeste Marcos, M Del Perpetuo Socorro Churruca, Enrique Zamora, Adrián Martínez, Mar Barrio Mayo, Rosalina Henares Espi, Rosa Méndez, David Arribas, Marta Chicot Llano, Begoña González, Begoña Quicios, Pablo Patiño, Marina Trigueros, Cristina Dominguez Peña, David Jiménez Jiménez, Pablo Villamayor, Alfonso Canabal, Rafael de la Cámara, Javier Ortiz, Isabel Iturrate
INTRODUCTION: SARS-CoV-2 viral load has been related to COVID-19 severity. The main aim of this study was to evaluate the relationship between SARS-CoV-2 viremia and SNPs in genes previously studied by our group as predictors of COVID-19 severity. MATERIALS AND METHODS: Retrospective observational study including 340 patients hospitalized for COVID-19 in the University Hospital La Princesa between March 2020 and December 2021, with at least one viremia determination...
2023: Frontiers in Medicine
#10
JOURNAL ARTICLE
Edvan de Queiroz Crusoe, Abrahão Elias Hallack Neto, Deise Ferreira Nantes, Eduardo Flavio Oliveira Ribeiro, Fernando Monteiro Correia Pinto, Jaisson Andre Pagnoncelli Bortolini, James Farley Rafael Maciel, Jose Francisco Comenalli Marques Junior, Lorena Costa Corrêa, Marcelo Eduardo Zanella Capra, Maria do Perpétuo Socorro Sampaio Carvalho, Nelcivone Soares de Melo, Rafaela Vasques de Oliveira Quintas, Thiago Xavier Carneiro, Violete Petitto Laforga, Renato Luiz Guerino Cunha
No abstract text is available yet for this article.
July 13, 2023: Hematology, Transfusion and Cell Therapy
#11
JOURNAL ARTICLE
Thinali Sousa Dantas, Paulo Goberlânio de Barros Silva, Osias Vieira de Oliveira Filho, Iana Aragão Magalhães, Ana Paula Negreiros Nunes Alves, Maria do Perpétuo Socorro Saldanha Cunha, Mário Rogério Lima Mota, Renata Ferreira de Carvalho Leitão, Fabrício Bitu Sousa
BACKGROUND: Opioids are the most effective drugs currently available for cancer pain management. The administration of morphine, in addition to its analgesic effect, can alter tumor development. OBJECTIVE: To characterize the immunoexpression of opioid receptors µ and κ in oropharyngeal squamous cell carcinoma, and correlate it with prognostic factors, proliferation markers, and cell death. MATERIALS AND METHODS: A retrospective, cross-sectional observational study was carried out with 50 patients diagnosed at Haroldo Juaçaba Hospital...
July 13, 2023: Journal of Stomatology, Oral and Maxillofacial Surgery
#12
JOURNAL ARTICLE
Daniela P Mendes-de-Almeida, Francianne G Andrade, Maria do Perpétuo Socorro Sampaio Carvalho, José Carlos Córdoba, Marcelo Dos Santos Souza, Paulo Chagas Neto, Logan G Spector, Maria S Pombo-de-Oliveira
BACKGROUND: Familial aggregation in childhood leukemia is associated with epidemiological and genomic factors. Albeit epidemiological studies on the familial history of hematological malignancies (FHHMs) are scarce, genome-wide studies have identified inherited gene variants associated with leukemia risk. We revisited a dataset of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients to explore the familial aggregation of malignancies among their relatives. METHODS: A series of 5,878 childhood leukemia (≤21 years of age) from the EMiLI study (2000-2019) were assessed...
2023: Frontiers in Oncology
#13
JOURNAL ARTICLE
Lara Helena Perpetuo, Wellington Ferreira, Danilo Jorge da Silva, Mauro Eduardo Jurno, Thiago Cardoso Vale
BACKGROUND: Delirium subsyndrome (SSD) and delirium (DL) are known complications in the intensive care unit (ICU) and are associated with worse clinical outcomes. The aim of this study was to screen for SSD and DL in individuals with COVID-19 admitted to the ICU and to study the associated factors and clinical outcomes. METHOD: An observational, longitudinal study was conducted in the reference ICU for COVID-19. All admitted individuals with COVID-19 were screened for SSD and DL during their ICU stay using the Intensive Care Delirium Screening Checklist (ICDSC)...
May 31, 2023: Journal of Clinical Medicine
#14
JOURNAL ARTICLE
Laura Soraia Perpétuo, Maria José M da Cunha, Maria Teresa Batista, Isabel Luci Conceição
Meloidogyne chitwoodi causes significant yield losses in many crops and the chemical control measures currently used are less effective for this nematode. The activity of aqueous extracts (0.8 mg/mL) of one-month-old (R1M) and two-months-old roots and immature fruits (F) of Solanum linnaeanum (Sl) and S. sisymbriifolium cv. Sis 6001 (Ss) were tested on hatching, mortality, infectivity and reproduction of M. chitwoodi . The extracts selected reduced the hatching of second-stage juveniles (J2) (cumulative hatching of 40% for Sl R1M and 24% for Ss F) but did not affect J2 mortality...
June 2023: Heliyon
#15
JOURNAL ARTICLE
Ana Paula de Sousa, Lucas Araújo Almeida, Breno Perpétuo Lourenço, Luiza Duarte Alvares, Mariana Arias Avila
PURPOSE: The aim of the present study was to investigate the effects of adding Pain Neuroscience Education (PNE) to an aquatic therapy protocol on pain, fibromyalgia (FMS) impact, quality of life and sleep. MATERIALS AND METHODS: Seventy-five women were randomly allocated into two groups: aquatic exercises (AEG, n = 36) and aquatic exercises + PNE (PNG, n = 39). The primary outcome was pain, and the secondary outcomes were FMS impact, quality of life, sleep and pain sensitivity (pressure pain thresholds - PPTs)...
April 18, 2023: Disability and Rehabilitation
#16
JOURNAL ARTICLE
Carla Perpétuo, Ana I Plácido, Jorge Aperta, Adolfo Figueiras, Maria Teresa Herdeiro, Fátima Roque
Aging is associated with an increase in the prevalence of chronic diseases and polypharmacy, and with the prescription of potentially inappropriate medications (PIMs). This study aimed to analyze the variation in PIMs from hospital admission to discharge. A retrospective cohort study was conducted on inpatients of an internal medicine service. According to the Beers criteria, 80.7% of the patients had been prescribed at least one PIM at admission and 87.2% at discharge; metoclopramide was the most-prescribed PIM from admission to discharge, and acetylsalicylic acid was the most-deprescribed one...
March 11, 2023: International Journal of Environmental Research and Public Health
#17
JOURNAL ARTICLE
Catarina Perpétuo, Mona El-Sheikh, Eva Diniz, Manuela Veríssimo
The security of attachment has been related to several advantageous developmental outcomes, such as good sleep quality and higher well-being indicators. However, few studies concern the associations between attachment dimensions to both parents, sleep, and well-being in late middle childhood. Our study aims to expand knowledge in this area, clarifying the above-mentioned associations by considering the secure base and safe haven dimensions of attachment. We also investigate the role of sleep as a mediator of the relationship between attachment and well-being...
February 15, 2023: International Journal of Environmental Research and Public Health
#18
JOURNAL ARTICLE
Bruna Bacaro Borrego, Louise Hase Gracioso, Bruno Karolski, Letícia Oliveira Bispo Cardoso, Letícia Beatriz Ueda Melo, Ítalo Braga Castro, Elen Aquino Perpetuo
Brazil is one of the countries most impacted along the entire coastline by the presence of tributyltin (TBT), a biocide used in antifouling paints. Despite being banned since 2008, its use is still registered in the country, and it is possible to find recent inputs of this substance in places under the influence of shipyards, marinas, and fishing ports. In this study, a bacterium isolated from TBT-contaminated sediment from Santos and São Vicente Estuarine System (SESS) in Brazil, identified as Achromobacter sp...
February 17, 2023: Marine Pollution Bulletin
#19
JOURNAL ARTICLE
Divane de Vargas, Dionasson Altivo Marques, Rosa Jacinto Volpato, Erika Gisseth Leon Ramirez, Maria do Perpétuo Socorro de Sousa Nobrega
OBJECTIVES: to perform content validity and verify the psychometric properties of the adapted version of an alcohol knowledge questionnaire and associated questions. METHODS: a methodological study, in which a committee of judges analyzed the questionnaire item representativeness, clarity and relevance. Item response theory was used to assess the instrument psychometric properties applied to a sample of 240 health professionals. RESULTS: the questions were adjusted according to judges' assessment, obtaining a satisfactory Content Validity Index (0...
2023: Revista Brasileira de Enfermagem
#20
REVIEW
Maria do Perpetuo Socorro de Sousa Coelho, Irislene Costa Pereira, Kynnara Gabriella Feitosa de Oliveira, Iara Katryne Fonseca Oliveira, Márcia Dos Santos Rizzo, Victor Alves de Oliveira, Felipe Cavalcanti Carneiro da Silva, Francisco Leonardo Torres-Leal, João Marcelo de Castro E Sousa
BACKGROUND: Vitamin E has been investigated for its antitumor potential, including the ability to change cancer gene pathways as well as promote antioxidant and pro-oxidant activity. OBJECTIVE: Therefore, this systematic review aimed to evaluate antitumor and chemopreventive activity of different vitamin E isoforms (tocopherols and tocotrienols) through in vitro and in vivo studies. METHOD: The systematic review was registered in PROSPERO (No...
February 2023: Clinical Nutrition ESPEN
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
