keyword
https://read.qxmd.com/read/38486220/effect-of-silicone-oil-versus-gas-tamponade-on-macular-layer-microstructure-after-pars-plana-vitrectomy-for-macula-on-rhegmatogenous-retinal-detachment
#1
JOURNAL ARTICLE
Abdulaziz Mohammed Al-Shehri, Saud Aljohani, Khalid Abdulaziz Aldihan, Musa Johaiman Alrashedi, Saad Alrasheed, Patrik Schatz
PURPOSE: To analyze structural changes in the macular retinal layers and sub-foveal choroidal thickness (SFCT) in eyes after macula-on rhegmatogenous retinal detachment (RRD) repair by pars plana vitrectomy with either silicone oil (SO) or gas tamponade, and the effect of these changes on visual acuity. PATIENTS AND METHODS: Retrospective study which included 26 eyes in the SO Group and 32 in the Gas Group. Optical coherence tomography (OCT) scans of the affected eyes were obtained before surgery, and 3 months after PPV in the Gas Group, and during silicone oil in situ and 3 months after SO removal, in the SO Group...
March 14, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38485744/three-dimensional-choroidal-contour-mapping-in-healthy-population
#2
JOURNAL ARTICLE
Supriya Arora, Sumit Randhir Singh, Brian Rosario, Mohammed Nasar Ibrahim, Amrish Selvam, Arman Zarnegar, Sanjana Harihar, Vinisha Sant, Jose Alain Sahel, Kiran Kumar Vupparaboina, Jay Chhablani
Purpose was to study 3-dimensional choroidal contour at choroidal inner boundary (CIB) and choroidal outer boundary (COB) in healthy eyes. Healthy eyes imaged on wide field swept-source optical coherence tomography were included. Delineation of CIB and COB was done based on our previously reported methods. Quantitative analysis of the surfaces of CIB and COB was based on analyzing best fit spherical radius (R) (overall and sectoral). One hundred and seven eyes of 74 subjects with a mean age of 46.4 ± 19...
March 14, 2024: Scientific Reports
https://read.qxmd.com/read/38476060/changes-in-retinal-hemodynamics-in-the-optic-nerve-head-of-healthy-participants-measured-using-laser-speckle-flowgraphy-after-a-cold-pressor-test
#3
JOURNAL ARTICLE
Shogo Sato, Yuki Hashimoto, Ami Sakamoto, Suzuka Nakano, Miki Yoshimura, Toshitaka Yamanokuchi, Takeshi Yoshitomi
PURPOSE: Autoregulation of retinal vessels is stronger than that of choroidal vessels. This study aimed to use laser speckle flowgraphy to determine the time course of changes in retinal hemodynamics of healthy eyes after a cold pressor test. METHODS: This prospective study included 44 right eyes of 44 healthy volunteers (age, 21.7 ± 5.0 years). The mean blur rate, which is a quantitative index of the relative blood flow velocity in the retina, was measured using laser speckle flowgraphy...
March 13, 2024: Korean Journal of Ophthalmology: KJO
https://read.qxmd.com/read/38466287/quantitative-evaluation-of-the-topographical-maps-of-three-dimensional-choroidal-vascularity-index-in-children-with-different-degrees-of-myopia
#4
JOURNAL ARTICLE
Fang Liu, Yuhao Ye, Weiming Yang, Jing Wang, Ye Xu, Yu Zhao, Meng Li, Zhi Chen, Yang Shen, Meiyan Li, Xingtao Zhou
PURPOSE: To investigate topographical maps of the three-dimensional choroidal vascularity index (3D-CVI) in children with different levels of myopia. METHODS: We enrolled 274 eyes from 143 children with various severity of myopia, including emmetropia (EM), low myopia (LM), and moderate-high myopia (MHM). The choroidal vessel volume (CVV), choroidal stroma volume (CSV), and 3D-CVI in different eccentricities (fovea, parafovea, and perifovea) and quadrants (nasal, temporal, superior, and inferior) were obtained from swept-source optical coherence tomography angiography (SS-OCTA) volume scans...
March 5, 2024: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/38462374/-preliminary-study-on-automatic-quantification-and-grading-of-leopard-spots-fundus-based-on-deep-learning-technology
#5
JOURNAL ARTICLE
L Dong, W D Zhou, L Ju, H Q Zhao, Y H Yang, L Shao, K M Song, L Wang, T Ma, Y X Wang, W B Wei
Objective: To achieve automatic segmentation, quantification, and grading of different regions of leopard spots fundus (FT) using deep learning technology. The analysis includes exploring the correlation between novel quantitative indicators, leopard spot fundus grades, and various systemic and ocular parameters. Methods: This was a cross-sectional study. The data were sourced from the Beijing Eye Study, a population-based longitudinal study. In 2001, a group of individuals aged 40 and above were surveyed in five urban communities in Haidian District and three rural communities in Daxing District of Beijing...
March 11, 2024: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://read.qxmd.com/read/38454842/analysis-of-foveal-avascular-zone-by-using-spectral-domain-optical-coherence-tomography-angiography-in-healthy-indian-eyes
#6
JOURNAL ARTICLE
Priyadarshi Gupta, Meenakshi Thakar, Ketaki Rajurkar, Kirti Jaisingh, Ekta Shaw, Taw Anne Dipu
PURPOSE: To analyze FAZ superficial (s) and deep (d) area and dimensions by using spectral-domain optical coherence tomography angiography (OCTA) in healthy eyes and to assess effect of age, gender, axial length (AL), central foveal thickness (CFT), and central choroidal thickness (CCT) on FAZ. We aimed to study FAZ dimensions with OCTA in healthy Indian eyes with the purpose of creating a normative database. SETTINGS AND DESIGN: Observational cross-sectional study...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454839/quantitative-and-comparative-analysis-of-thermography-parameters-in-posterior-scleritis-choroiditis-and-controls
#7
JOURNAL ARTICLE
Ankush Kawali, Aayesha Khanum, Sai Bhakti Mishra, Srinivasan Sanjay, Padmamalini Mahendradas, Rohit Shetty
PURPOSE: To compare various ocular thermography parameters in posterior scleritis (PS), choroiditis (choroidal granuloma [CG], Vogt-Koyanagi-Harada [VKH] syndrome), central serous chorioretinopathy (CSCR), and healthy controls. METHODS: This retrospective, observational, comparative study evaluated cases undergoing ocular thermography between April 2017 and October 2023. The study groups included cases of PS, CG, and VKH, while the control group comprised CSCR cases and healthy individuals...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38452795/optical-coherence-tomography-angiography-in-the-diagnosis-of-ocular-disease
#8
REVIEW
Michael Kalloniatis, Henrietta Wang, Jack Phu, Janelle Tong, James Armitage
Clinical imaging provided by optical coherence tomography (OCT) and its variant, OCT-angiography (OCT-A), has revolutionised eyecare practice. The imaging techniques allow for the identification and quantification of ocular structures, supporting the diagnosis and prognosis of eye disease. In this review, an overview of the usefulness of OCT-A imaging in the diagnosis and management of a range of ocular conditions is provided when used in isolation or in combination with other imaging modalities and measures of visual function (visual field results)...
March 7, 2024: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://read.qxmd.com/read/38432946/protective-effect-of-pemafibrate-treatment-against-diabetic-retinopathy-in-spontaneously-diabetic-torii-fatty-rats
#9
JOURNAL ARTICLE
Yoshiaki Tanaka, Rina Takagi, Shingen Mitou, Machiko Shimmura, Tetsuya Hasegawa, Jota Amarume, Masami Shinohara, Yasushi Kageyama, Tomohiko Sasase, Takeshi Ohta, Shin-Ichi Muramatsu, Akihiro Kakehashi, Toshikatsu Kaburaki
Diabetic retinopathy (DR) can cause visual impairment and blindness, and the increasing global prevalence of diabetes underscores the need for effective therapies to prevent and treat DR. Therefore, this study aimed to evaluate the protective effect of pemafibrate treatment against DR, using a Spontaneously Diabetic Torii (SDT) fatty rat model of obese type 2 diabetes. SDT fatty rats were fed either a diet supplemented with pemafibrate (0.3 mg/kg/day) for 16 weeks, starting at 8 weeks of age (Pf SDT fatty: study group), or normal chow (SDT fatty: controls)...
March 1, 2024: Biological & Pharmaceutical Bulletin
https://read.qxmd.com/read/38428557/an-automated-comparative-analysis-of-the-exudative-biomarkers-in-neovascular-age-related-macular-degeneration-the-rap-study-report-6
#10
JOURNAL ARTICLE
Bilal Haj Najeeb, Bianca S Gerendas, Gabor G Deak, Oliver Leingang, Hrvoje Bogunovic, Ursula Schmidt-Erfurth
PURPOSE: To explore the differences in volume and distribution of exudative biomarkers across macular neovascularization (MNV) types and subtypes using artificial intelligence (AI). DESIGN: Cross-sectional study. METHODS: We applied an AI-based analysis of 34.528 OCT b-scans of 281 (250 unifocal, 31 multifocal) MNV3, 55 MNV2, and 121 (30 polypoidal, 91 non-polypoidal) MNV1 treatment-naïve eyes. We compared the means (standard deviations) and heat maps of cystic intraretinal fluid (IRF), subretinal fluid (SRF), pigment epithelial detachments (PED) and hyperreflective foci (HRF) volumes, as well as retinal thickness (RT) among MNV (sub)types...
February 28, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38426594/two-stage-adversarial-learning-based-unsupervised-domain-adaptation-for-retinal-oct-segmentation
#11
JOURNAL ARTICLE
Shengyong Diao, Ziting Yin, Xinjian Chen, Menghan Li, Weifang Zhu, Muhammad Mateen, Xun Xu, Fei Shi, Ying Fan
BACKGROUND: Deep learning based optical coherence tomography (OCT) segmentation methods have achieved excellent results, allowing quantitative analysis of large-scale data. However, OCT images are often acquired by different devices or under different imaging protocols, which leads to serious domain shift problem. This in turn results in performance degradation of segmentation models. PURPOSE: Aiming at the domain shift problem, we propose a two-stage adversarial learning based network (TSANet) that accomplishes unsupervised cross-domain OCT segmentation...
March 1, 2024: Medical Physics
https://read.qxmd.com/read/38424598/deep-learning-segmentation-of-the-choroid-plexus-from-structural-magnetic-resonance-imaging-mri-validation-and-normative-ranges-across-the-adult-lifespan
#12
JOURNAL ARTICLE
Jarrod J Eisma, Colin D McKnight, Kilian Hett, Jason Elenberger, Caleb J Han, Alexander K Song, Ciaran Considine, Daniel O Claassen, Manus J Donahue
BACKGROUND: The choroid plexus functions as the blood-cerebrospinal fluid (CSF) barrier, plays an important role in CSF production and circulation, and has gained increased attention in light of the recent elucidation of CSF circulation dysfunction in neurodegenerative conditions. However, methods for routinely quantifying choroid plexus volume are suboptimal and require technical improvements and validation. Here, we propose three deep learning models that can segment the choroid plexus from commonly-acquired anatomical MRI data and report performance metrics and changes across the adult lifespan...
February 29, 2024: Fluids and Barriers of the CNS
https://read.qxmd.com/read/38413514/effects-of-hemoglobin-concentration-on-retinochoroidal-vascular-plexuses-an-optical-coherence-tomography-angiography-study
#13
JOURNAL ARTICLE
Selda Celik Dulger, Seda Cevik Kaya, Turgay Fen, Mehmet Yasin Teke
PURPOSE: To evaluate retinal and choroidal microvascular structures using optical coherence tomography angiography (OCTA) in patients with anemia and polycythemia vera (PV). METHODS: In this prospective study, 142 patients (142 eyes) were enrolled and divided into 3 groups: the anemia (n = 56), PV (n = 46), and healthy groups (n = 40, controls). For each patient, 6- × 6-mm macular angiography images were taken using an OCTA system (optovue, Inc...
February 28, 2024: International Ophthalmology
https://read.qxmd.com/read/38409823/pitchfork-sign-following-pars-plana-vitrectomy-for-idiopathic-epiretinal-membrane-a-case-report
#14
JOURNAL ARTICLE
Francesco Gelormini, Guglielmo Parisi, Veronica Vallino, Federico Ricardi, Paola Marolo, Enrico Borrelli, Michele Reibaldi
PURPOSE: To report a case of pitchfork sign following pars plana vitrectomy for idiopathic epiretinal membrane. STUDY DESIGN: Case report. RESULTS: A 75-year-old man was referred to the surgical retina service due to a quantitative and qualitative decline in vision in the left eye (LE) for several months. Optical coherence tomography (OCT) examination revealed the presence of a stage III epiretinal membrane (ERM) according to the Govetto classification...
February 26, 2024: European Journal of Ophthalmology
https://read.qxmd.com/read/38409562/choroid-plexus-volume-in-multiple-sclerosis-can-be-estimated-on-structural-mri-avoiding-contrast-injection
#15
JOURNAL ARTICLE
Valentina Visani, Francesca B Pizzini, Valerio Natale, Agnese Tamanti, Mariagiulia Anglani, Alessandra Bertoldo, Massimiliano Calabrese, Marco Castellaro
We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23...
February 27, 2024: European Radiology Experimental
https://read.qxmd.com/read/38409198/quantitative-microvascular-analysis-in-different-stages-of-retinitis-pigmentosa-using-optical-coherence-tomography-angiography
#16
JOURNAL ARTICLE
Richul Oh, Kunho Bae, Chang Ki Yoon, Un Chul Park, Kyu Hyung Park, Eun Kyoung Lee
As retinitis pigmentosa (RP) is chronic and progressive, the chronological sequence of microvascular changes is important for understanding its pathophysiology. We aimed to investigate retinal and choroidal microvascular changes according to the RP stages. The stages of RP were classified into three stages according to the integrity and width of the inner segment ellipsoid zone: early, ≥ 2500 μm; moderate, < 2500 μm; advanced, absence. Using optical coherence tomography angiography, quantitative microvascular parameters were analyzed...
February 26, 2024: Scientific Reports
https://read.qxmd.com/read/38389841/transfer-rna-derived-fragment-trf-glu-ctc-aggravates-the-development-of-neovascular-age-related-macular-degeneration
#17
JOURNAL ARTICLE
Yu Liang, Lingjie Kong, Yuelu Zhang, Yihan Zhang, Mingsu Shi, Jiaqiu Huang, Hongyu Kong, Siyi Qi, Yunlong Yang, Jiaxu Hong, Meidong Zhu, Xiangjia Zhu, Xinghuai Sun, Shujie Zhang, Lianqun Wu, Chen Zhao
Rationale: Angiogenesis expedites tissue impairment in many diseases, including age-related macular degeneration (AMD), a leading cause of irreversible blindness in elderly. A substantial proportion of neovascular AMD patients, characterized by aberrant choroidal neovascularization (CNV), exhibit poor responses or adverse reactions to anti-VEGF therapy. Herein, we aimed to unveil the function of newly identified transfer RNA-derived small RNA, tRF-Glu-CTC, in the pathology of CNV and determine its potential in inhibiting angiogenesis...
2024: Theranostics
https://read.qxmd.com/read/38373920/quantitative-evaluation-of-ocular-vascularity-and-correlation-analysis-in-patients-with-diabetic-retinopathy-by-smi-and-octa
#18
JOURNAL ARTICLE
Jin Wei, Chong Chen, Yinchen Shen, Fang Li, Shu Yiyang, Haiyun Liu
AIMS: To find potential relation between retrobulbar vessels and fundus microvessels and to detect sensitive and effective clinical indicators in predicting the progress of diabetic retinopathy (DR), ocular hemodynamics were measured using superb microvascular imaging (SMI) and ultrawide-field optical coherence tomography angiography (UWF-OCTA). METHODS: Observational, cross-sectional study evaluating ocular hemodynamics in patients with DR by SMI (Aplio i900, Canon Medical) and UWF-OCTA (BM-400 K BMizar, Tupai Medical Technology)...
February 19, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38349785/mass-spectrometry-based-profiling-of-histone-post-translational-modifications-in-uveal-melanoma-tissues-human-melanocytes-and-uveal-melanoma-cell-lines-a-pilot-study
#19
JOURNAL ARTICLE
Martina C Herwig-Carl, Amit Sharma, Verena Tischler, Natalie Pelusi, Karin U Loeffler, Frank G Holz, Michael Zeschnigk, Solange Landreville, Claudia Auw-Haedrich, Roberta Noberini, Tiziana Bonaldi
PURPOSE: Epigenetic alterations in uveal melanoma (UM) are still neither well characterized, nor understood. In this pilot study, we sought to provide a deeper insight into the possible role of epigenetic alterations in the pathogenesis of UM and their potential prognostic relevance. To this aim, we comprehensively profiled histone post-translational modifications (PTMs), which represent epigenetic features regulating chromatin accessibility and gene transcription, in UM formalin-fixed paraffin-embedded (FFPE) tissues, control tissues, UM cell lines, and healthy melanocytes...
February 1, 2024: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/38300640/association-of-plasma-markers-of-alzheimer-s-disease-neurodegeneration-and-neuroinflammation-with-the-choroid-plexus-integrity-in-aging
#20
JOURNAL ARTICLE
Mustapha Bouhrara, Keenan A Walker, Joseph S R Alisch, Zhaoyuan Gong, Caio H Mazucanti, Alexandria Lewis, Abhay R Moghekar, Lisa Turek, Victoria Collingham, Nader Shehadeh, Giovanna Fantoni, Mary Kaileh, Christopher M Bergeron, Jan Bergeron, Susan M Resnick, Josephine M Egan
The choroid plexus (CP) is a vital brain structure essential for cerebrospinal fluid (CSF) production. Moreover, alterations in the CP's structure and function are implicated in molecular conditions and neuropathologies including multiple sclerosis, Alzheimer's disease, and stroke. Our goal is to provide the first characterization of the association between variation in the CP microstructure and macrostructure/volume using advanced magnetic resonance imaging (MRI) methodology, and blood-based biomarkers of Alzheimer's disease (Aß42/40 ratio; pTau181), neuroinflammation and neuronal injury (GFAP; NfL)...
January 8, 2024: Aging and Disease
keyword
keyword
161667
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.