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Lobe-specific Node Dissection

Hiroyuki Kayata, Mitsuhiro Isaka, Yukihiro Terada, Kiyomichi Mizuno, Yoshiyuki Yasuura, Hideaki Kojima, Yasuhisa Ohde
OBJECTIVES: The indication of limited resection for radiographically pure-solid, small-sized lung adenocarcinoma is controversial. This study aimed to reveal the long-term outcome of standard surgical treatment and determine the predictive factors for pathological lymph node metastasis in optimal candidates undergoing limited surgical resection for pure-solid, small-sized lung adenocarcinoma. METHODS: The medical records of 107 consecutive patients were retrospectively reviewed at our hospital between December 2002 and December 2013...
January 9, 2019: General Thoracic and Cardiovascular Surgery
Makoto Endoh, Hiroyuki Oizumi, Hirohisa Kato, Jun Suzuki, Hikaru Watarai, Akira Hamada, Katsuyuki Suzuki, Kenta Nakahashi, Satoshi Shiono, Mitsuaki Sadahiro
Background: Hyperbaric oxygen therapy (HBOT) has been used successfully in the treatment of specific ischemic injuries, but has been a little evaluated specifically in postoperative ischemic bronchitis (POIB). The purpose of this study was to evaluate the effect of HBOT when used for POIB after resection of lung cancer. Methods: From January 1999 to December 2016, 1,100 patients underwent lymph node dissection (LND) and either anatomic pulmonary resection or lung resection with bronchoplasty for lung cancer...
November 2018: Journal of Thoracic Disease
Hélène Bohec, Ingrid Breuskin, Julien Hadoux, Martin Schlumberger, Sophie Leboulleux, Dana M Hartl
OBJECTIVE: Therapeutic lateral neck dissection (ND) is recommended for N1b papillary thyroid carcinoma (PTC), while prophylactic contralateral lateral ND is not. Given the paucity of data, we investigated the frequency of and risk factors for occult lymph node metastases (LNM) in the contralateral lateral neck for N1b patients. PATIENTS AND METHODS: This is a retrospective study conducted at a cancer center. Inclusion criteria were: unilateral PTC and ipsilateral lateral LNM confirmed by fine-needle aspiration biopsy...
November 21, 2018: World Journal of Surgery
Han-Yu Deng, Miao Zeng, Gang Li, Guha Alai, Jun Luo, Lun-Xu Liu, Qinghua Zhou, Yi-Dan Lin
BACKGROUND: Controversy still exists in which subtype of non-small-cell lung cancer [squamous cell carcinoma (SCC) or adenocarcinoma] is more likely to have lymph node (LN) metastasis. The aim of this study is to compare the pattern of LN metastasis in two cohorts of matched patients surgically treated for SCC or adenocarcinoma. METHODS: A retrospective analysis of patients undergoing lobectomy or segmentectomy with systematic lymphadenectomy without preoperative treatment for lung SCC or adenocarcinoma was conducted in this study...
November 13, 2018: World Journal of Surgery
Bailu Du, Yue Tao, Jing Ma, Xing Weng, Yanping Gong, Yang Lin, Nan Shen, Xi Mo, Qing Cao
The incidence of sparganosis, a parasitic disease caused by plerocercoid larvae of the genus Spirometra, has gradually risen worldwide (especially in remote areas) in recent years. Pulmonary and pleural sparganosis, as well as other sites of infestation, including the subcutaneous tissues, the abdominal viscera, brain and eyes, has been reported. In clinical practice, due to the atypical signs and symptoms as well as limited laboratory approaches for the specific detection of sparganum, sparganosis is often misdiagnosed...
October 11, 2018: Infection, Genetics and Evolution
Zeead M AlGhamdi, Lyfuxu Lynhiavu, Young Kyu Moon, Mi Hyoung Moon, Seha Ahn, Yunho Kim, Sook Whan Sung
Background: Non-intubated, or awake, video-assisted thoracoscopic surgery has been implemented for non-anatomical lung resection and the results obtained were encouraging to consider the approach for anatomical pulmonary resection. This study was conducted to evaluate the perioperative outcomes of the non-intubated and intubated video-assisted thoracoscopic lobectomy in lung cancer in regards to feasibility and safety. Methods: A retrospective analysis of 62 consecutive video-assisted thoracoscopic lobectomies (31 lobectomies as non-intubated, 31 lobectomies as intubated) performed in Seoul St...
July 2018: Journal of Thoracic Disease
Ningning Ding, Yousheng Mao, Shugeng Gao, Qi Xue, Dali Wang, Jun Zhao, Yushun Gao, Jinfeng Huang, Kang Shao, Feiyue Feng, Yue Zhao, Ligong Yuan
Background: The pathologic stages of lymph nodes usually differ from preoperatively predicted in lung cancers and it is difficult to predict the metastasis of lymph nodes for the patients diagnosed as clinical stage IA non-small cell lung cancers (NSCLC). This study aimed to investigate the patterns of lymph node metastasis and the risk factors predicting lymph node metastasis in the patients with clinical stage IA NSCLCs. Methods: All patients diagnosed as clinical stage IA NSCLC from July 2013 to June 2017 in our center were retrospectively reviewed, and a total number of 1,543 patients who underwent anatomical lobectomy with systematic lymph node dissection were enrolled in this study...
July 2018: Journal of Thoracic Disease
Run-Bin Liang, Jie Yang, Tai-Shan Zeng, Hao Long, Jian-Hua Fu, Lan-Jun Zhang, Peng Lin, Xin Wang, Tie-Hua Rong, Xue Hou, Hao-Xian Yang
OBJECTIVE: We aimed to investigate the incidence and distribution of mediastinal lymph node metastases (MLNM) in operable non-small cell lung cancer (NSCLC) with the purpose of guiding mediastinal lymph node dissection (MLND). METHODS: A total of 4511 NSCLC patients who underwent resection between January 2001 and December 2014 were included. These patients were preoperatively untreated and grouped according to the primary tumor lobes. The incidence and distribution of pathologic MLNM were compared among groups, and multivariate analysis was conducted to find the independent factors impacting MLNM...
October 2018: Annals of Surgical Oncology
Han-Yu Deng, Chang-Long Qin, Gang Li, Guha Alai, Yidan Lin, Xiao-Ming Qiu, Qinghua Zhou
Background: Whether lobe-specific lymph node dissection (L-SLND) could serve as an alternative to systematic lymph node dissection (SLND) in treating early-stage non-small cell lung cancer (NSCLC) remains unclear. Therefore, we conducted this comprehensive meta-analysis to compare the effect of L-SLND with that of SLND in treating early-stage NSCLC. Methods: A systematic literature search in PubMed and Embase was conducted to identify relevant studies up to 30 November 2017...
May 2018: Journal of Thoracic Disease
T Zhang, Y Qu, L He, L Shao, D L Zhang, C Z Lü, P Zhang, H Zhang
Objective: To investigate the risk factors and preoperative evaluation of lymph nodes posterior to right recurrent laryngeal nerve (LN-prRLN) metastasis in papillary thyroid carcinoma (PTC). Methods: Clinical data of 301 patients with right or double lobes who underwent surgery between August 2015 and October 2016 in the Department of Thyroid Surgery, the First Hospital of China Medical University, were retrospectively analyzed. The relationships between LN-prRLN metastasis and clinical pathology data and other factors were analyzed...
June 12, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Catarina Carvalheiro, Javier Gallego-Poveda, Diego Gonzalez-Rivas, Jorge Cruz
INTRODUCTION: Interest in uniportal video-assisted thoracic surgery (VATS) is rapidly growing worldwide because it represents the surgical approach to the lung with the least possible trauma and in recent years the subxiphoid approach has been used in the field of thoracic surgery as it is associated with lesser pain because there is no intercostal nerve damage and it provides excellent cosmetic outcomes. This technique was recently introduced for major pulmonary resections and even bilateral approaches in selected patients...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
Katrine Jensen, René Horsleben Petersen, Henrik Jessen Hansen, William Walker, Jesper Holst Pedersen, Lars Konge
BACKGROUND: Specific assessment tools can accelerate trainees' learning through structured feedback and ensure that trainees attain the knowledge and skills required to practice as competent, independent surgeons (competency-based surgical education). The objective was to develop an assessment tool for video-assisted thoracoscopic surgery (VATS) lobectomy by achieving consensus within an international group of VATS experts. METHOD: The Delphi method was used as a structured process for collecting and distilling knowledge from a group of internationally recognized VATS experts...
October 2018: Surgical Endoscopy
Xiangyang Yu, Yingsheng Wen, Rongqing Qin, Yongbin Lin, Xuewen Zhang, Weidong Wang, Yongqiang Chen, Lanjun Zhang
BACKGROUND: Primary pulmonary lymphoepithelioma-like carcinoma is a rare subtype of lung cancer. Until now, the characteristics of lymph nodes metastases in resectable cases have not yet been reported. METHODS: In this study, a total of 87 consecutive patients with primary pulmonary lymphoepithelioma-like carcinoma that received surgical treatment were investigated from October 1999 to August 2016. The clinical and radiological data and follow-up information were extracted from hospital records in detail...
March 2018: Thoracic Cancer
Hiroyuki Adachi, Takamitsu Maehara, Haruhiko Nakayama, Munetaka Masuda
No abstract text is available yet for this article.
September 2017: Journal of Thoracic Disease
Tomoyuki Hishida, Hisashi Saji, Shun-Ichi Watanabe, Hisao Asamura, Keiju Aokage, Tomonori Mizutani, Masashi Wakabayashi, Taro Shibata, Morihito Okada
In January 2017, the Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group commenced a randomized Phase III trial to confirm the clinical benefit of lobe-specific nodal dissection for clinical Stage I-II non-small cell lung cancer. The primary endpoint is overall survival, and the main objective is to confirm the non-inferiority of lobe-specific in comparison to systematic nodal dissection with regard to lobectomy. The secondary endpoints are relapse-free survival, %local recurrence, %regional lymph node recurrence, operation time, blood loss, length of hospitalization, duration of chest tube placement and adverse events...
February 1, 2018: Japanese Journal of Clinical Oncology
Han Han, Haiquan Chen
Lymph node dissection is a vital part of surgical treatment in early-stage non-small cell lung cancer (NSCLC). Removal of metastatic lymph nodes while preservation of intact lymph nodes are equally important. For hospitalized early-stage patients with limited lymph node metastasis, the operation treatment should be made according to some rules such as lobe-specific lymph node drainage pattern. In order to prevent unnecessary surgical trauma in early-stage patients, a minimally invasive approach with selective lymph node excision is preferred for more clinical benefits...
July 2017: Journal of Thoracic Disease
Karolien E Goffin, Steven Joniau, Peter Tenke, Kevin Slawin, Eric A Klein, Nancy Stambler, Thomas Strack, John Babich, Thomas Armor, Vivien Wong
(99m)Tc-trofolastat ((99m)Tc-MIP-1404), a small-molecule inhibitor of prostate-specific membrane antigen, shows high potential to detect prostate cancer (PCa) noninvasively using SPECT. We therefore wanted to assess the performance of (99m)Tc-trofolastat SPECT/CT in a phase 2 multicenter, multireader prospective study in patients with intermediate- and high-grade PCa, before radical prostatectomy and extended pelvic lymph node (LN) dissection, with histopathology as the gold standard. Methods: PCa patients (n = 105) with an increased risk of LN involvement (LNI) underwent pelvic (99m)Tc-trofolastat SPECT/CT before radical prostatectomy with extended pelvic LN dissection...
September 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
Andrea Bille, Kaitlin M Woo, Usman Ahmad, Nabil P Rizk, David R Jones
Objectives: Early clinical stage (T1 and T2) non-small cell lung cancer (NSCLC) is commonly treated with anatomic lung resection and lymph node sampling or dissection. The aims of this study were to evaluate the incidence and the distribution of occult N2 disease according to tumour location and the short- and long-term outcomes. Methods: We performed a retrospective review of patients with clinical stage I NSCLC who underwent anatomic lung resection and lymphadenectomy...
April 1, 2017: European Journal of Cardio-thoracic Surgery
Stylianos Korasidis, Cecilia Menna, Claudio Andreetti, Giulio Maurizi, Antonio D'Andrilli, Anna Maria Ciccone, Francesco Cassiano, Erino Angelo Rendina, Mohsen Ibrahim
An accurate staging of a malignant disease is imperative in order to plan pre- and post-operative therapy, define prognosis and compare studies. According to the European Society of Thoracic Surgeons (ESTS) guidelines a systematic lymph node (LN) dissection is recommended in all cases of pulmonary resection for non-small cell lung cancer (NSCLC). The current lung cancer staging system considers the lymphatic stations involved but not the number of LNs. Up to date, published scientific studies on hilar and mediastinal lymphadenectomy mainly have been regarded the type of LN dissection procedure after pulmonary resection (selected LN biopsy, LN sampling, systematic nodal dissection, lobe specific nodal dissection and extended LN dissection) focusing particularly on the comparison between mediastinal LN dissection (MLND) and mediastinal LN sampling (MLNS)...
October 2016: Annals of Translational Medicine
Frank C Detterbeck
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Oncology
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