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JOURNAL ARTICLE
Aymeric Hermann, Pamela Gutiérrez, Catherine Chauvel, René Maury, Céline Liorzou, Edson Willie, Iarawai Phillip, Robert Forkel, Christoph Rzymski, Stuart Bedford
Although the peopling of Remote Oceania is well-documented as a general process of eastward migrations from Island Southeast Asia and Near Oceania toward the archipelagos of Remote Oceania, the origin and the development of Polynesian societies in the Western Pacific (Polynesian Outliers), far away from the Polynesian triangle, remain unclear. Here, we present a large-scale geochemical sourcing study of stone artifacts excavated from archeological sites in central Vanuatu, the Solomon Islands, and the Caroline Islands and provide unambiguous evidence of multiple long-distance voyages, with exotic stone materials being transported up to 2500 kilometers from their source...
April 21, 2023: Science Advances
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JOURNAL ARTICLE
Yogesh K Gupta, Francismar C Marcelino-Guimarães, Cécile Lorrain, Andrew Farmer, Sajeet Haridas, Everton Geraldo Capote Ferreira, Valéria S Lopes-Caitar, Liliane Santana Oliveira, Emmanuelle Morin, Stephanie Widdison, Connor Cameron, Yoshihiro Inoue, Kathrin Thor, Kelly Robinson, Elodie Drula, Bernard Henrissat, Kurt LaButti, Aline Mara Rudsit Bini, Eric Paget, Vasanth Singan, Christopher Daum, Cécile Dorme, Milan van Hoek, Antoine Janssen, Lucie Chandat, Yannick Tarriotte, Jake Richardson, Bernardo do Vale Araújo Melo, Alexander H J Wittenberg, Harrie Schneiders, Stephane Peyrard, Larissa Goulart Zanardo, Valéria Cristina Holtman, Flavie Coulombier-Chauvel, Tobias I Link, Dirk Balmer, André N Müller, Sabine Kind, Stefan Bohnert, Louisa Wirtz, Cindy Chen, Mi Yan, Vivian Ng, Pierrick Gautier, Maurício Conrado Meyer, Ralf Thomas Voegele, Qingli Liu, Igor V Grigoriev, Uwe Conrath, Sérgio H Brommonschenkel, Marco Loehrer, Ulrich Schaffrath, Catherine Sirven, Gabriel Scalliet, Sébastien Duplessis, H Peter van Esse
With >7000 species the order of rust fungi has a disproportionately large impact on agriculture, horticulture, forestry and foreign ecosystems. The infectious spores are typically dikaryotic, a feature unique to fungi in which two haploid nuclei reside in the same cell. A key example is Phakopsora pachyrhizi, the causal agent of Asian soybean rust disease, one of the world's most economically damaging agricultural diseases. Despite P. pachyrhizi's impact, the exceptional size and complexity of its genome prevented generation of an accurate genome assembly...
April 1, 2023: Nature Communications
#23
JOURNAL ARTICLE
Come Sesboue, Jean Galtier, Marie Jeanneau, Annick Chauvel, Elodie Laharanne, Samuel Amintas, Jean-Philippe Merlio, Krimo Bouabdallah, François-Xavier Gros, Laurence de Leval, Audrey Gros, Marie Parrens
Distinguishing between follicular lymphoma (FL) and nodal marginal zone lymphoma (NMZL) can be difficult when morphologic and phenotypic features are unusual and characteristic cytogenetic rearrangements are absent. We evaluated the diagnostic contribution of ancillary techniques-including fluorescence in situ hybridization (FISH)-detected 1p36 deletion; reverse-transcriptase, multiplex, ligation-dependent probe amplification (RT-MLPA); and next-generation sequencing (NGS)-for tumors that remain unclassified according to standard criteria...
February 2023: Modern Pathology
#24
Thomas Jezequel, Nathalie Cheron, Rezarta Ajazi Hub, Carole Brouillat, Elodie Colonnese, Claire Desmedt, Solène Evard, Séverine Hie, Cécilia Mourrut, Déborah Vallade, Isabelle Bouhier, Céline Chauvel, Virginie Gandemer, Lara Mercier, Ibrahim Yakoub-Agha
Like the "nurse practitioner" in Anglo-Saxon countries, the French health authority validated on January 2016 the creation of an intermediate grade called advanced practice nurse (APN). They are authorized to carry out an assessment of the person's state of health, through a complete clinical examination. They can also prescribe additional examinations necessary for the monitoring of the pathology, and carry out certain acts for diagnostic and/or therapeutic purposes. Given the specificities of cellular therapy patients, the content of university professional training doesn't seem sufficient to assure an optimal management by the APN of these patients...
February 14, 2023: Bulletin du Cancer
#25
JOURNAL ARTICLE
Julie Chauvel-Picard, Linda Tognetti, Elisa Cinotti, Cyril Habougit, Mariano Suppa, Clement Lenoir, Pietro Rubegni, Veronique Del Marmol, Vincent Berot, Arnaud Gleizal, Paul Vercherin, Guillame Dejonckheere, Charles Raffaelli, Nathalie Cardot-Leccia, Nicholas Azulay, Anne Sudaka-Bahadoran, Jean L Perrot, Philippe Bahadoran
BACKGROUND: Ultrasound imaging has recently benefited from the introduction of a new 70 MHz transducer able to provide high-resolution images, i.e.: ultra-high-frequency ultrasound (UHFUS). OBJECTIVES: To study the morphological features of Basal Cell Carcinoma (BCC) and measure BCC thickness by means of UHFUS examination. METHODS: This retrospective multicentric study included 171 consecutive patients that underwent UHFUS examination between November 2018 and May 2019 for suspeted BCC...
January 6, 2023: Clinical and Experimental Dermatology
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JOURNAL ARTICLE
Federico Di Rocco, Massimiliano Rossi, Isabelle Verlut, Alexandru Szathmari, Pierre Aurélien Beuriat, Nicolas Chatron, Julie Chauvel-Picard, Carmine Mottolese, Pauline Monin, Matthieu Vinchon, Sofia Guernouche, Corinne Collet
In some cases of infants with apparently isolated single-suture synostosis, an underlying variant can be found. We aimed to determine the molecular substratum in isolated sagittal and metopic craniosynostosis. To this end, we included all infants who presented isolated midline synostosis (sagittal or metopic) and had undergone surgery at the craniosynostosis national reference center of Lyon University Hospital. All infants were examined by a multidisciplinary team including neurosurgeons, clinical geneticists and neuropsychologist...
June 2023: European Journal of Human Genetics: EJHG
#27
JOURNAL ARTICLE
Arnaud Gleizal, Pierre Gagnieur, Stéphane Tringali, Nicolas Nimeskern, Maxime Fieux, Julie Chauvel-Picard
INTRODUCTION: The aim of this study was to determine the predisposing factors of this deafness after orthognathic surgery for a population with no history of cleft palate. MATERIAL AND METHODS: All patients with significant auditory symptoms after orthognathic surgery performed in the department of Craniomaxillofacial surgery in the Croix Rousse Hospital, Lyon, France, since 2012 were included in the study. The exclusion criterion was a history of cleft palate. Bone movements performed during orthognathic surgery were analyzed...
January 24, 2023: Journal of Stomatology, Oral and Maxillofacial Surgery
#28
REVIEW
Caroline Mélou, Pascal Pellen-Mussi, Sylvie Jeanne, Agnès Novella, Sylvie Tricot-Doleux, Dominique Chauvel-Lebret
Background and Objectives : This study reviewed the literature to summarize the current and recent knowledge of temporomandibular joint osteoarthritis (TMJOA). Methods : Through a literature review, this work summarizes many concepts related to TMJOA. Results : Although many signaling pathways have been investigated, the etiopathogenesis of TMJOA remains unclear. Some clinical signs are suggestive of TMJOA; however, diagnosis is mainly based on radiological findings. Treatment options include noninvasive, minimally invasive, and surgical techniques...
December 20, 2022: Medicina
#29
JOURNAL ARTICLE
Murielle Chauvel, Sophie Bachellier-Bassi, Anne-Marie Guérout, Keunsook K Lee, Corinne Maufrais, Emmanuelle Permal, Juliana Pipoli Da Fonseca, Sadri Znaidi, Didier Mazel, Carol A Munro, Christophe d'Enfert, Melanie Legrand
Candida albicans is a major fungal pathogen of humans. Although its genome has been sequenced more than two decades ago, there are still over 4,300 uncharacterized C. albicans genes. We previously generated an ORFeome as well as a collection of destination vectors to facilitate overexpression of C. albicans ORFs. Here, we report the construction of ∼2,500 overexpression mutants and their evaluation by in vitro spotting on rich medium and in a liquid pool experiment in rich medium, allowing the identification of genes whose overexpression has a fitness cost...
December 29, 2022: Research in Microbiology
#30
JOURNAL ARTICLE
Reinaldo Dal Bello, Kim Pacchiardi, Clémentine Chauvel, Lionel Adès, Thorsten Braun, Justine Pasanisi, Elise Fournier, Céline Berthon, Emmanuelle Clappier, Emmanuel Raffoux, Delphine Lebon, Thomas Cluzeau, Christophe Roumier, Adriana Plesa, Karine Celli-Lebras, Hervé Dombret, Claude Preudhomme, Stéphanie Mathis, Alexandre Puissant, Claude Gardin, Raphael Itzykson
No abstract text is available yet for this article.
January 2023: HemaSphere
#31
JOURNAL ARTICLE
Laxmi Shanker Rai, Murielle Chauvel, Emmanuelle Permal, Christophe d'Enfert, Sophie Bachellier-Bassi
Candida albicans, the most prevalent fungal pathogen in the human microbiota can form biofilms on implanted medical devices. These biofilms are tolerant to conventional antifungal drugs and the host immune system as compared to the free-floating planktonic cells. Several in vitro models of biofilm formation have been used to determine the C. albicans biofilm-forming process, regulatory networks, and their properties. Here, we performed a genome-wide transcript profiling with C. albicans cells grown in YPD medium both in planktonic and biofilm condition...
December 16, 2022: Research in Microbiology
#32
JOURNAL ARTICLE
Laetitia Souchet, Stavroula Masouridi, Ambroise Marçais, Ahmad Ibrahim, Celine Chauvel, Eric Turquet, Marion Derail, Ibrahim Yakoub-Agha, Roberto Crocchiolo
Acute GVHD is a potentially severe complication of hematopoietic stem cell transplantation, responsible for morbidity and mortality that can affect the prognosis after transplantation. Within the framework of the 12th workshop of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC), diagnostic modalities of acute GVHD are updated. The conventional prevention (depending on donor, conditioning, and stem cell source) and treatment schemes (depending on affected organ and intensity) of aGVHD are clarified, and new therapeutic options are discussed...
November 24, 2022: Bulletin du Cancer
#33
JOURNAL ARTICLE
F Daniel Ramirez, Marianna Meo, Corentin Dallet, Philipp Krisai, Konstantinos Vlachos, Antonio Frontera, Masateru Takigawa, Yosuke Nakatani, Takashi Nakashima, Clémentine André, Tsukasa Kamakura, Takamitsu Takagi, Aline Carapezzi, Romain Tixier, Rémi Chauvel, Ghassen Cheniti, Josselin Duchateau, Thomas Pambrun, Frédéric Sacher, Mélèze Hocini, Michel Haïssaguerre, Pierre Jaïs, Rémi Dubois, Nicolas Derval
BACKGROUND: Bipolar voltage is widely used to characterize the atrial substrate but has been poorly validated, particularly during clinical tachycardias. OBJECTIVE: The purpose of this study was to evaluate the diagnostic performance of voltage thresholds for identifying regions of slow conduction during reentrant atrial tachycardias (ATs). METHODS: Thirty bipolar voltage and activation maps created during reentrant ATs were analyzed to (1) examine the relationship between voltage amplitude and conduction velocity (CV), (2) measure the diagnostic ability of voltage thresholds to predict CV, and (3) identify determinants of AT circuit dimensions...
March 2023: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#34
JOURNAL ARTICLE
Thomas Bonnin, Pierre Roumegou, Soumaya Sridi, Saagar Mahida, Aurélien Bustin, Josselin Duchateau, Romain Tixier, Nicolas Derval, Thomas Pambrun, Ghassen Chniti, Takamitsu Takagi, Tsukasa Kamakura, Philipp Krisai, Clementine Andre, Rémi Chauvel, Meleze Hocini, Michel Haissaguerre, Pierre Jais, Hubert Cochet, Frederic Sacher
AIMS: Assess prevalence, risk factors, and management of patients with intra-cardiac thrombus referred for scar-related ventricular tachycardia (VT) ablation. METHODS AND RESULTS: Consecutive VT ablation referrals between January 2015 and December 2019 were reviewed (n = 618). Patients referred for de novo, scar-related VT ablation who underwent pre-procedure cardiac computed tomography (cCT) were included. We included 401 patients [61 ± 14 years; 364 male; left ventricular ejection fraction (LVEF) 40 ± 13%]; 45 patients (11%) had cardiac thrombi on cCT at 49 sites [29 LV; eight left atrial appendage (LAA); eight right ventricle (RV); four right atrial appendage]...
November 10, 2022: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#35
JOURNAL ARTICLE
O Moranne, F Chauvel, E Pambrun, P Ahmadpoor, C Prelipcean, A Wuillai, S Chkair, Z Messikh
INTRODUCTION: Certain patients require simultaneous lipoprotein apheresis (LA) and intermittent hemodialysis (HD). Instead of undergoing 2 consecutive treatment sessions, a double filtration plasmapheresis (DFPP) and HD tandem procedure could be offered to reduce treatment times and costs. Our study evaluated the performance, safety and cost of this tandem procedure. MATERIAL AND METHODS: Three patients underwent 168 HD and DFPP tandem sessions in a tertiary center from August 2018 to November 2020, using a Fresenius 5008 generator for HD and an InfomedHF440 for DFPP...
October 2022: Journal of Clinical Apheresis
#36
JOURNAL ARTICLE
Lisa Gillinder, Jason Papacostas, Pamela McCombe, Patrick Chauvel
Objective: Immunity is increasingly implicated in the aetiology of certain types of epilepsy, however, the clinical and EEG features in such cases remain poorly defined. We present stereo-electroencephalography (SEEG) findings in patients who were thought to have autoantibody-mediated epilepsy on the basis of clinical improvement after administration of immunotherapy (IT). Methods: All patients undergoing SEEG implantation in our service were reviewed and those receiving immunotherapy, either before, during, or after SEEG evaluation, were identified...
December 1, 2022: Epileptic Disorders: International Epilepsy Journal with Videotape
#37
JOURNAL ARTICLE
Gaps after linear ablation of persistent atrial fibrillation, (Marshall-PLAN): clinical implication.
Takamitsu Takagi, Nicolas Derval, Josselin Duchateau, Rémi Chauvel, Romain Tixier, Hugo Marchand, Benjamin Bouyer, Clémentine André, Tsukasa Kamakura, Philipp Krisai, Ciro Ascione, Conrado Balbo, Ghassen Cheniti, Arnaud Denis, Frédéric Sacher, Mélèze Hocini, Pierre Jaïs, Michel Haïssaguerre, Thomas Pambrun
BACKGROUND: Beyond pulmonary vein (PV) isolation, anatomic isthmuses transection is an adjunctive strategy for persistent atrial fibrillation (AF). Data on the durability of multiple lines of block remain scarce. OBJECTIVE: To evaluate the impact of gaps within such a lesion set. METHODS: We followed 291 consecutive patients who underwent: (1) vein of Marshall ethanol infusion, (2) PV isolation, and (3) mitral, cavotricuspid, and dome isthmuses transection...
September 14, 2022: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#38
JOURNAL ARTICLE
Vanessa C Bieker, Paul Battlay, Bent Petersen, Xin Sun, Jonathan Wilson, Jaelle C Brealey, François Bretagnolle, Kristin Nurkowski, Chris Lee, Fátima Sánchez Barreiro, Gregory L Owens, Jacqueline Y Lee, Fabian L Kellner, Lotte van Boheeman, Shyam Gopalakrishnan, Myriam Gaudeul, Heinz Mueller-Schaerer, Suzanne Lommen, Gerhard Karrer, Bruno Chauvel, Yan Sun, Bojan Kostantinovic, Love Dalén, Péter Poczai, Loren H Rieseberg, M Thomas P Gilbert, Kathryn A Hodgins, Michael D Martin
Invasive species are a key driver of the global biodiversity crisis, but the drivers of invasiveness, including the role of pathogens, remain debated. We investigated the genomic basis of invasiveness in Ambrosia artemisiifolia (common ragweed), introduced to Europe in the late 19th century, by resequencing 655 ragweed genomes, including 308 herbarium specimens collected up to 190 years ago. In invasive European populations, we found selection signatures in defense genes and lower prevalence of disease-inducing plant pathogens...
August 26, 2022: Science Advances
#39
JOURNAL ARTICLE
C Liégeois-Chauvel, A-S Dubarry, I Wang, P Chauvel, J A Gonzalez-Martinez, F-X Alario
The current standard model of language production involves a sensorimotor dorsal stream connecting areas in the temporo-parietal junction with those in the inferior frontal gyrus and lateral premotor cortex. These regions have been linked to various aspects of word production such as phonological processing or articulatory programming, primarily through neuropsychological and functional imaging group studies. Most if not all the theoretical descriptions of this model imply that the same network should be identifiable across individual speakers...
August 23, 2022: European Journal of Neuroscience
#40
JOURNAL ARTICLE
The Glycoprotein M6a Is Associated with Invasiveness and Radioresistance of Glioblastoma Stem Cells.
Marie Geraldine Lacore, Caroline Delmas, Yvan Nicaise, Aline Kowalski-Chauvel, Elizabeth Cohen-Jonathan-Moyal, Catherine Seva
Systematic recurrence of glioblastoma (GB) despite surgery and chemo-radiotherapy is due to GB stem cells (GBSC), which are particularly invasive and radioresistant. Therefore, there is a need to identify new factors that might be targeted to decrease GBSC invasive capabilities as well as radioresistance. Patient-derived GBSC were used in this study to demonstrate a higher expression of the glycoprotein M6a (GPM6A) in invasive GBSC compared to non-invasive cells. In 3D invasion assays performed on primary neurospheres of GBSC, we showed that blocking GPM6A expression by siRNA significantly reduced cell invasion...
July 6, 2022: Cells
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