Vilmaris Quinones Cardona, Rakesh Rao, Isabella Zaniletti, Priscilla Joe, Yvette R Johnson, Robert DiGeronimo, Shannon E Hamrick, Kyong-Soon Lee, Ulrike Mietzsch, Girija Natarajan, Eric S Peeples, Tai-Wei Wu, Tanzeema Hossain, John Flibotte, Amit Chandel, Amy Distler, Jeffrey S Shenberger, Onome Oghifobibi, An N Massaro, Maria L V Dizon
IMPORTANCE: Intercenter variation exists in the management of hypoxic-ischemic encephalopathy (HIE). It is unclear whether increased resource utilization translates into improved neurodevelopmental outcomes. OBJECTIVE: To determine if higher resource utilization during the first 4 days of age, quantified by hospital costs, is associated with survival without neurodevelopmental impairment (NDI) among infants with HIE. DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort analysis of neonates with HIE who underwent therapeutic hypothermia (TH) at US children's hospitals participating in the Children's Hospitals Neonatal Database between 2010 and 2016...
March 1, 2023: JAMA Network Open