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https://read.qxmd.com/read/30768758/two-years-supervised-resistance-training-prevented-diabetes-incidence-in-people-with-prediabetes-a-randomized-control-trial
#1
Xia Dai, Lu Zhai, Qingyun Chen, Joshua D Miller, Lirong Lu, Cunyi Hsue, Lin Liu, Xiaodan Yuan, Wei Wei, Xiaojun Ma, Zhaohui Fang, Wenpiao Zhao, Yuhua Liu, Feng Huang, Qingqing Lou
AIM: To explore the long-term effects of aerobic training (AT), resistance training (RT) and combined training (AT+RT) on the prevention of T2D incidence in patients with prediabetes. MATERIALS AND METHODS: In this randomized controlled trial, people with prediabetes (fasting glucose ≥5.6 mmol/L and <7.0 mmol/L and/or 2-hour glucose ≥7.8 mmol/L and <11.1 mmol/L on the 75-g oral glucose-tolerance test and/or haemoglobin A1c ≥5.7% and <6.4%) were randomly assigned to the control group, AT group, RT group or AT+RT group...
February 15, 2019: Diabetes/metabolism Research and Reviews
https://read.qxmd.com/read/30768553/predicting-energy-expenditure-of-an-acute-resistance-exercise
#2
Jason R Lytle, Danielle M Kravits, Steven E Martin, John S Green, Stephen F Crouse, Brad S Lambert
Energy expenditure of resistance exercise (RE) is an important consideration for exercise prescription and weight management, yet prediction models are lacking. PURPOSE: To develop regression equations to predict energy expenditure (kcal) for RE involving each major muscle group using commonly measured demographic and exercise variables as predictors. METHODS: Fifty-two healthy, active subjects (27 men, 25 women, age 20-58 years, height 174.1 ± 10.5 cm, weight 188...
February 13, 2019: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/30768470/why-we-needn-t-fear-the-machines-opportunities-for-medicine-in-a-machine-learning-world
#3
David Li, Kulamakan Kulasegaram, Brian D Hodges
Recently in medicine, the accuracy of machine learning models in predictive tasks has started to meet or exceed that of board certified specialists. The ability to automate cognitive tasks using software has raised new questions about the future role of human physicians in health care. Emerging technologies can displace people from their jobs, forcing them to learn new skills, so it is clear that this looming challenge needs to be addressed by the medical education system. While current medical education seeks to prepare the next generation of physicians for a rapidly evolving health care landscape to meet the needs of the communities they serve, strategic decisions about disruptive technologies should be informed by a deeper investigation of how machine learning will function in the context of medicine...
February 12, 2019: Academic Medicine: Journal of the Association of American Medical Colleges
https://read.qxmd.com/read/30768448/unilateral-strength-training-and-mirror-therapy-in-chronic-stroke-patients-a-pilot-randomised-trial
#4
Monika Ehrensberger, Daniel Simpson, Patrick Broderick, Catherine Blake, Frances Horgan, Paula Hickey, Joanne O'Reilly, Kenneth Monaghan
OBJECTIVE: This study aimed to investigate the feasibility and potential effectiveness of mirror-aided cross-education compared to cross-education alone in post-stroke upper limb recovery. DESIGN: A pilot randomized controlled parallel group study was carried out. Thirty-two chronic stroke patients followed a 4-week isometric strength-training programme performed with the less-affected upper limb 3 times per week. Participants in the mirror and strength training group observed the reflection of the exercising arm in the mirror; Participants in the strength training only group exercised without a mirror entirely...
February 13, 2019: American Journal of Physical Medicine & Rehabilitation
https://read.qxmd.com/read/30767690/content-validity-of-the-sos-wrist-questionnaire-for-timely-identification-of-wrist-overuse-in-young-athletes
#5
L S Kox, P P F M Kuijer, J Opperman, G M J J Kerkhoffs, M Maas, M H W Frings-Dresen
Objectives Young athletes do not always seek medical help for overuse wrist injuries, risking invalidating long-term consequences resulting from late diagnosis. This study aimed to develop a questionnaire to identify overuse wrist injuries in young athletes. Methods According to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) criteria, items were collected from literature and 6 focus groups of sports physicians and of young athletes with (previous) overuse wrist injuries...
February 15, 2019: Physician and Sportsmedicine
https://read.qxmd.com/read/30767562/opening-the-door-to-physical-activity-for-children-with-cerebral-palsy-experiences-of-participants-in-the-befast-or-bestrong-program
#6
Sarpreet Kahlon, Kiah Brubacher-Cressman, Erica Caron, Keren Ramonov, Ruth Taubman, Katherine Berg, F Virginia Wright, Alicia J Hilderley
This study explored children's experiences of participating in one-to-one physical training programs to identify how programs can best promote physical activity participation for children with cerebral palsy. A qualitative descriptive design with self-determination theory was used. Semistructured interviews were conducted with 6 children with cerebral palsy, age 8-14 years, who participated in a fundamental-movement-skills or lower-limb strength-training program. A hybrid approach of deductive and inductive analysis was used...
February 15, 2019: Adapted Physical Activity Quarterly: APAQ
https://read.qxmd.com/read/30766550/impact-of-weight-reduction-on-insulin-resistance-adhesive-molecules-and-adipokines-dysregulation-among-obese-type-2-diabetic-patients
#7
Shehab M Abd El-Kader, Osama H Al-Jiffri
Background: Type 2 diabetes mellitus is usually related to vascular problems and is associated with impairment in endothelial function characterized by impaired endothelial-dependent vasodilation and increased platelet adhesion. There is limitation in clinical studies that have addressed the beneficial effects of weight reduction in modulating biomarkers of endothelial dysfunction and adipokines dysregulation for obesity associated with type 2 diabetes mellitus. Objective: This study was designed to detect the effects of weight loss on insulin resistance, adhesive molecules and adipokines dysregulation in obese type 2 diabetic patients...
December 2018: African Health Sciences
https://read.qxmd.com/read/30766508/effectiveness-of-robot-assisted-upper-limb-training-on-spasticity-function-and-muscle-activity-in-chronic-stroke-patients-treated-with-botulinum-toxin-a-randomized-single-blinded-controlled-trial
#8
Marialuisa Gandolfi, Nicola Valè, Eleonora Kirilova Dimitrova, Stefano Mazzoleni, Elena Battini, Mirko Filippetti, Alessandro Picelli, Andrea Santamato, Michele Gravina, Leopold Saltuari, Nicola Smania
Background: The combined use of Robot-assisted UL training and Botulinum toxin (BoNT) appear to be a promising therapeutic synergism to improve UL function in chronic stroke patients. Objective: To evaluate the effects of Robot-assisted UL training on UL spasticity, function, muscle strength and the electromyographic UL muscles activity in chronic stroke patients treated with Botulinum toxin. Methods: This single-blind, randomized, controlled trial involved 32 chronic stroke outpatients with UL spastic hemiparesis...
2019: Frontiers in Neurology
https://read.qxmd.com/read/30766462/effects-of-six-weeks-of-resistance-endurance-training-on-microrna-29-expression-in-the-heart-of-ovariectomised-rats
#9
Morteza Jourkesh, Rahman Soori, Conrad P Earnest, Lamia Mirheidari, Ali Asghar Ravasi, Stephen R Stannard, Matias Monsalves-Alvarez
Introduction: Heart disease risk rises with age. However, women's symptoms become more pronounced following the onset of menopause. The aim of the present study was to evaluate the effects of six weeks of combined resistance-endurance (RE) training on microRNA-29 expression in the heart of ovariectomised rats. Material and methods: Thirty female Wistar rats were divided into three groups: 1) sham (SHAM); 2) ovariectomy (OVX); and 3) OVX with RE training (OVX + RE)...
December 2018: Przeglad Menopauzalny, Menopause Review
https://read.qxmd.com/read/30765926/endocrine-responses-following-exhaustive-strength-exercise-with-and-without-the-use-of-protein-and-protein-carbohydrate-supplements
#10
Michał Wilk, Małgorzata Michalczyk, Artur Gołaś, Michał Krzysztofik, Adam Maszczyk, Adam Zając
The aim of this study was to determine the effect of carbohydrate-protein supplementation with whey protein (CHO-PROw) after resistance training, and casein protein (PROc) before bedtime on the concentration of growth hormone (GH), insulin (I) and insulin-like growth factor (IGF-1), as well as serum creatine kinase (CK) activity. Twelve strength trained male subjects (age: 25.8 ± 4.7 years; training experience 6.1 ± 0.79 years; body mass 75.9 ± 2.7 kg; body height 171.8 ± 13.3 cm) were recruited for the study...
December 2018: Biology of Sport
https://read.qxmd.com/read/30765919/jump-training-with-blood-flow-restriction-has-no-effect-on-jump-performance
#11
Masahiro Horiuchi, Junko Endo, Takashi Sato, Koichi Okita
This study investigated whether jump training with blood flow restriction (BFR) improves jump performance compared to jump training without BFR under similar exercise intensity in healthy young humans. The participants were twenty healthy males who were assigned to either jump training with BFR (n = 10) or jump training without BFR [control (CON); n = 10] groups. All subjects completed five sets of 10 repetitions with one-minute intervals of half-squat jumps (SJ) at maximal effort, four days a week for four weeks...
December 2018: Biology of Sport
https://read.qxmd.com/read/30765916/attention-deficit-hyperactivity-disorder-medication-does-not-alter-exercise-induced-hypoalgesia-following-an-acute-bout-of-dynamic-circuit-resistance-exercise
#12
Chelsea C McKean, Brandon A Baiamonte, Robert R Kraemer, Daniel B Hollander
The primary goal of this study was to investigate the effects of attention-deficit/hyperactivity disorder (ADHD) medications on exercise-induced hypoalgesia (EIH), heart rate, and perceived exertion. Thirty college-age students (10 Controls, 10 ADHD diagnosis, and 10 ADHD diagnosis with medications) completed 2 sessions: 1) a maximal testing session and 2) an experimental session consisting of 3 consecutive dynamic resistance exercise circuits comprised of 12 repetitions of 9 exercises at 60% of 1-repetition maximum using a 1:1 work to rest ratio...
December 2018: Biology of Sport
https://read.qxmd.com/read/30765419/digital-immunohistochemistry-implementation-training-and-validation-experience-and-technical-notes-from-a-large-clinical-laboratory
#13
Bethany Jill Williams, Dharshana Jayewardene, Darren Treanor
AIMS: To consider the value proposition of digitisation of clinical immunohistochemistry services, and to develop an approach to digital immunohistochemistry implementation and validation in a large clinical laboratory. METHODS: A methodology for slide scanning in the laboratory was developed, in addition to a novel validation exercise, to allow pathologists to identify the strengths and weaknesses of digital immunohistochemistry reporting, and train in digital immunohistochemistry slide assessment...
February 14, 2019: Journal of Clinical Pathology
https://read.qxmd.com/read/30764860/pulmonary-rehabilitation-in-patients-with-mustard-gas-lung-disease-a-study-protocol-for-a-randomized-controlled-trial
#14
Mohamad Reza Sedighi Moghadam, Mostafa Ghanei, Klaus Kenn, Nicholas S Hopkinson
BACKGROUND: More than 60,000 people have health problems due to chemical weapons exposure during the Iran-Iraq war. Respiratory consequences of mustard gas exposure are common and disabling; medical interventions have limited effect. Patients complain of cough, sputum, breathlessness and exercise limitation. We hypothesized that patients with this condition would benefit from pulmonary rehabilitation. METHODS: We outline the protocol for an assessor-blind, two-armed, parallel-design randomized controlled clinical trial (IRCT2016051127848N1)...
February 14, 2019: Trials
https://read.qxmd.com/read/30764853/persistent-exercise-limitation-after-successful-pulmonary-endoarterectomy-frequency-and-determinants
#15
Angelo G Corsico, Andrea M D'Armini, Valentina Conio, Antonio Sciortino, Maurizio Pin, Valentina Grazioli, Giulia Di Vincenzo, Rita Di Domenica, Anna Celentano, Benedetta Vanini, Amelia Grosso, Erica Gini, Federica Albicini, Vera N Merli, Vanessa Ronzoni, Stefano Ghio, Catherine Klersy, Isa Cerveri
BACKGROUND: After successful pulmonary endoarterectomy (PEA), patients may still suffer from exercise limitation, despite normal pulmonary vascular resistance. We sought to assess the proportion of these patients after the extension of PEA to frail patients, and the determinants of exercise limitation. METHODS: Out of 553 patients treated with PEA from 2008 to 2016 at our institution, a cohort of 261 patients was followed up at 12 months. They underwent clinical, haemodynamic, echocardiographic, respiratory function tests and treadmill exercise testing...
February 14, 2019: Respiratory Research
https://read.qxmd.com/read/30764759/self-report-occupational-related-contact-dermatitis-prevalence-and-risk-factors-among-healthcare-workers-in-gondar-town-northwest-ethiopia-2018-a-cross-sectional-study
#16
Tesfaye Hambisa Mekonnen, Dawit Getachew Yenealem, Beyene Mindaye Tolosa
BACKGROUND: Occupational skin diseases are the second most common occupational diseases and are responsible for an estimated 25% of all lost work days. Occupational contact dermatitis (OCD) comprises 70-90% of all occupational skin diseases. In Ethiopia, information about the prevalence and factors which determine developments of contact dermatitis is not recognized. The objective of this study was to investigate prevalence and factors influencing the occurrences of occupational-related contact dermatitis among healthcare workers in Gondar town, Northwest Ethiopia...
February 14, 2019: Environmental Health and Preventive Medicine
https://read.qxmd.com/read/30764646/a-randomised-controlled-trial-of-the-group-stepping-stones-triple-p-training-programme-for-parents-of-children-with-developmental-disabilities
#17
Ailbhe Ruane, Alan Carr, Valerie Moffat, Tania Finn, Angela Murphy, Orla O'Brien, Hilary Groarke, Roisin O'Dwyer
The central aim of this study was to examine the effectiveness of Group Stepping Stones Triple P (GSSTP) in an Irish context for families of children with both developmental disabilities and internalising and externalising behavioural problems. Parents of 84 children (mean age = 5.73; SD = 2.06) with developmental disabilities and co-occurring behaviour problems attending Irish public health services were randomly assigned to a 9-week GSSTP group or a waiting list control (WLC) group. All parents completed self-report measures before (Time 1) and after (Time 2) the programme and parents in the GSSTP group were assessed at 3- to 5-month follow-up (Time 3)...
February 15, 2019: Clinical Child Psychology and Psychiatry
https://read.qxmd.com/read/30763169/inactivity-induces-resistance-to-the-metabolic-benefits-following-acute-exercise
#18
John D Akins, Charles K Crawford, Heath M Burton, Anthony S Wolfe, Emre Vardarli, Edward F Coyle
Acute exercise improves postprandial lipemia, glucose tolerance, and insulin sensitivity, all of which are risk factors for cardiovascular disease. However, recent research suggests that prolonged sedentary behavior might abolish these healthy metabolic benefits. Accordingly, this study aimed to elucidate the impact of an acute bout of exercise on postprandial plasma triglyceride, glucose, and insulin concentrations after four days of prolonged sitting (~13.5 hrs/day). METHODS: Ten untrained to recreationally active men (n=5) and women (n=5) completed a counterbalanced, crossover study...
February 14, 2019: Journal of Applied Physiology
https://read.qxmd.com/read/30762623/the-additive-effects-of-creatine-supplementation-and-exercise-training-in-an-aging-population-a-systematic-review-of-randomized-controlled-trials
#19
Aaron Stares, Mona Bains
BACKGROUND AND PURPOSE: The role of creatine supplementation in young athletes and bodybuilders is well established including ergogenic properties of muscular hypertrophy, strength, power, and endurance. Whether the benefits of creatine supplementation translate to an aging population with moderate training stimulus remains unclear especially in regard to gender, creatine dose, and duration. This systematic review assessed whether creatine supplementation combined with exercise results in additive improvements in indices of skeletal muscle, bone, and mental health over exercise alone in healthy older adults...
February 8, 2019: Journal of Geriatric Physical Therapy
https://read.qxmd.com/read/30762468/deleterious-effects-of-cold-air-inhalation-on-coronary-physiological-indices-in-patients-with-obstructive-coronary-artery-disease
#20
Rupert P Williams, Kaleab N Asrress, Matthew Lumley, Satpal Arri, Tiffany Patterson, Howard Ellis, Vasiliki Manou-Stathopoulou, Catherine Macfarlane, Shruthi Chandran, Kostantinos Moschonas, Pippa Oakeshott, Timothy Lockie, Amedeo Chiribiri, Brian Clapp, Divaka Perera, Sven Plein, Michael S Marber, Simon R Redwood
Background Cold air inhalation during exercise increases cardiac mortality, but the pathophysiology is unclear. During cold and exercise, dual-sensor intracoronary wires measured coronary microvascular resistance ( MVR ) and blood flow velocity ( CBF ), and cardiac magnetic resonance measured subendocardial perfusion. Methods and Results Forty-two patients (62±9 years) undergoing cardiac catheterization, 32 with obstructive coronary stenoses and 10 without, performed either (1) 5 minutes of cold air inhalation (5°F) or (2) two 5-minute supine-cycling periods: 1 at room temperature and 1 during cold air inhalation (5°F) (randomized order)...
July 17, 2018: Journal of the American Heart Association
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