keyword
Keywords Severe Acute Pancreatitis-Inci...

Severe Acute Pancreatitis-Incidence Of Organ Failure

https://read.qxmd.com/read/38459563/analysis-of-the-clinical-profile-and-treatment-efficiency-of-hyperlipidemic-acute-pancreatitis
#1
JOURNAL ARTICLE
Weidong Zhou, Qinfu Liu, Zhaojun Wang, Liying Yao, Jian Chen, Xiaojun Yang
BACKGROUND: The incidence of hyperlipidemic acute pancreatitis (HLAP) has been increasing annually. However, population-based morbidity assessments need to be updated. Early, rapid, and effective lipid-lowering may minimize pancreatic injury and improve clinical prognosis. It is essential to choose the proper treatment. However, treatment options for HLAP are controversial, and there is no uniform treatment protocol. METHODS: In this retrospective study, 127 patients with hyperlipidemic severe acute pancreatitis (HL-SAP) were registered from January 2018 to December 2022 at the General Hospital of Ningxia Medical University...
March 8, 2024: Lipids in Health and Disease
https://read.qxmd.com/read/38350790/association-between-serum-triglyceride-level-and-severity-of-acute-biliary-pancreatitis
#2
JOURNAL ARTICLE
Qian Zhang, Qingcheng Xu, Quping Zhu, Lei Zhu, Changbao Pan, Juan Chen, Jun Liu, Denghao Deng, Weiwei Chen, Chaowu Chen
BACKGROUND: Acute biliary pancreatitis (ABP) is the most common type of acute pancreatitis. However, the effect of serum triglyceride (TG) levels on the severity of ABP remains unclear. The aim of this study was to assess the correlation between serum TG levels and the severity of ABP. METHODS: Data from 526 ABP patients was analyzed in this study. The patients were divided into normal and elevated groups according to the TG level measured within 24 h after admission, and the elevated group was further divided into mild, moderate, and severe elevated groups...
February 6, 2024: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://read.qxmd.com/read/38216100/qing-xia-jie-yi-formula-qxjyf-granules-alleviated-acute-pancreatitis-through-inhibition-of-m1-macrophage-polarization-by-suppressing-glycolysis
#3
JOURNAL ARTICLE
Xiao Han, Jingpiao Bao, Jianbo Ni, Bin Li, Pengli Song, Rong Wan, Xingpeng Wang, Guoyong Hu, Congying Chen
ETHNOPHARMACOLOGICAL RELEVANCE: Herbal formulas from Traditional Chinese Medicine are common and well-established practice for treating acute pancreatitis (AP) patients. However, little is known about their bioactive ingredients and mechanisms, such as their targets and pathways to inhibit inflammation. AIM OF THE STUDY: This study aimed to evaluate the effect of Qing Xia Jie Yi Formula (QXJYF) granules on AP and discuss the molecular mechanisms involved. MATERIALS AND METHODS: Major compounds in QXJYF granules were identified using UPLC-quadrupole-Orbitrap mass spectrometry (UPLC-Q-Orbitrap MS)...
January 10, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38212524/a-single-center-experience-of-non-bioartificial-dfapp-support-systems-among-chinese-patients-with-hyperlipidemic-moderate-severe-acute-pancreatitis
#4
JOURNAL ARTICLE
Xianwen Cheng, Yanrong Zhan, Zhendong Wang, Feng Wang, Xia Zeng, Ya Mao, YaoShun Liu
To assess the clinical efficacy of Double Filtration Plasmapheresis (DFAPP), a novel blood purification method, in treating hyperlipidemic moderate/severe pancreatitis (HL-M/SAP). A total of 68 HL-M/SAP patients were enrolled in this study. The observation group, comprising 34 patients, received DFAPP treatment, while the control group underwent CVVH + PA treatment. We compared the efficacy changes between the two groups post-treatment. Patients treated with DFAPP showed significant improvements in clinical outcomes...
January 11, 2024: Scientific Reports
https://read.qxmd.com/read/38102709/a-retrospective-analysis-of-the-clinical-efficacy-of-pancreatic-duct-stent-implantation-in-the-management-of-acute-biliary-pancreatitis-requiring-ercp
#5
JOURNAL ARTICLE
Bo Peng, Zuoquan Wang, Chengsi Zhao, Genwang Wang, Di Liu, Tongtong Dong, Jinping Shi, Zuozheng Wang, Weijie Yao
BACKGROUND: This study aimed to investigate the feasibility, effectiveness, and safety of pancreatic duct stenting in managing acute biliary pancreatitis (ABP) necessitating endoscopic retrograde cholangiopancreatography (ERCP). It further aimed to provide valuable insights for subsequent clinical diagnosis and treatment. METHODS: This research employs an observational retrospective case-control study design, encompassing patients with ABP who underwent ERCP at the hepatobiliary surgery department of the General Hospital of Ningxia Medical University between August 1, 2018, and December 31, 2020...
December 15, 2023: European Journal of Medical Research
https://read.qxmd.com/read/37989670/serum-cys-c-predicts-acute-kidney-injury-in-patients-with-acute-pancreatitis-a-retrospective-study
#6
JOURNAL ARTICLE
Ningzhi Wang, Fei Han, Jiajia Pan, Guanghuai Yao, Yao Wang, Songxin Xu, Weiming Xiao, Yanbing Ding, Chunfang Xu
BACKGROUND AND STUDY AIMS: We investigated the value of the serum cystatin C level as a potential predictor of acute kidney injury (AKI) in patients with acute pancreatitis (AP). PATIENTS AND METHODS: We retrospectively examined patients diagnosed with AP between January 2013 and December 2018. Patients were categorized into two groups based on their serum cystatin C levels after admission: the normal (n-Cys C group) and high serum cystatin C levels groups (h-Cys C group)...
November 20, 2023: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/37943383/etiological-changes-and-prognosis-of-hospitalized-patients-with-acute-pancreatitis-over-a-15-year-period
#7
JOURNAL ARTICLE
Tianming Lai, Jiarong Li, Zhengang Zhou, Jingwen Rao, Yong Zhu, Liang Xia, Yupeng Lei, Xin Huang, Huajing Ke, Yao Wu, Pi Liu, Hao Zeng, Huifang Xiong, Lingyu Luo, Youxiang Chen, Wenhua He, Yin Zhu, Nonghua Lu
BACKGROUND: The worldwide incidence of acute pancreatitis (AP) is increasing, but the dominant etiology of AP may vary by country. Mixed etiologies are involved in the increase in the number of AP patients. AIMS: This study was to analyze the etiological changes and prognosis of AP patients and explore the prognosis of AP patients with mixed etiologies. METHODS: Using a retrospective analysis method, AP patients hospitalized from January 2007 to December 2021 were selected from a pancreatic center in Nanchang, China...
November 9, 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/37903709/severe-liver-injury-and-clinical-characteristics-of-occupational-exposure-to-2-amino-5-chloro-n-3-dimethylbenzamide-a-case-series
#8
JOURNAL ARTICLE
Meng-Xiao Feng, Hua Zou, Yuan-Qiang Lu
BACKGROUND: The 2-amino-5-chloro-N,3-dimethylbenzamide is a key intermediate in the synthesis of pesticides and pharmaceuticals. However, no literature currently exists on 2-amino-5-chloro-N,3-dimethylbenzamide poisoning in humans. This study aimed to reveal the health hazard of this chemical for humans and summarize the clinical characteristics of patients with occupational 2-amino-5-chloro-N,3-dimethylbenzamide poisoning. METHODS: This observational study included four patients with 2-amino-5-chloro-N,3-dimethylbenzamide poisoning from June 2022 to July 2022...
April 2024: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://read.qxmd.com/read/37873711/-study-of-perioperative-safety-of-laparoscopic-pancreaticoduodenectomy-in-elderly-patients
#9
JOURNAL ARTICLE
Daofu Feng, Yizeng Wang, Jizhe Li, Baozhu Li, Nan Li
OBJECTIVE: To investigate the safety of laparoscopic pancreaticoduodenectomy (LPD) in elderly patients and the related risk factors admitted to the intensive care unit (ICU) after LPD. METHODS: The perioperative data of patients who underwent LPD in Tianjin Medical University General Hospital from February 2017 to June 2023 were retrospectively collected, including basic data, preoperative laboratory indicators, intraoperative and postoperative indicators, pathological results (tumor size, lymph node dissection and pathological type), postoperative complications, ICU postoperative management and prognosis...
October 2023: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/37866998/comparison-of-different-intensive-triglyceride-lowering-therapies-in-patients-with-hyperlipidemic-acute-pancreatitis
#10
JOURNAL ARTICLE
Wan Pu, Wen Tang, Yaoliang Shen, Fengjie Ji, Jiujing Huang, Yuxin Liu, Jing Zhou, Guojian Yin
OBJECTIVES: The goal of this study was to investigate the clinical value of emergent triglyceride (TG)-lowering therapies for hyperlipidemic acute pancreatitis (HLAP). METHODS: 126 HLAP patients were assigned randomly to receive either conventional treatment (CT), normal saline (NS) alone, or continuous veno-venous hemofiltration (CVVH) as an intensive TG-lowering therapy. TG levels, clinical outcomes, and inflammatory biomarkers were compared among the three groups...
October 13, 2023: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://read.qxmd.com/read/37710167/relation-between-triglycerides-and-the-severity-of-acute-pancreatitis-combined-with-nonalcoholic-fatty-liver-disease-a-retrospective-study
#11
JOURNAL ARTICLE
Lei Zhu, Leyao Yuan, Tingting Wang, Quping Zhu, Qian Zhang, Changbao Pan, Qingcheng Xu, Denghao Deng, Weiwei Chen, Juan Chen
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) can exacerbate the severity of acute pancreatitis (AP), and this severity is worsened with increased severity of NAFLD. This study aimed to investigate the relation between serum triglyceride (TG) and the severity of AP with NAFLD by collecting clinical data from AP patients with NAFLD. METHODS: AP patients with NAFLD were divided into 2 groups according to TG levels: hypertriglyceridemia (HTG) group and non-hypertriglyceridemia (NHTG) group...
September 14, 2023: BMC Gastroenterology
https://read.qxmd.com/read/37637352/a-clinic-radiomics-model-for-predicting-the-incidence-of-persistent-organ-failure-in-patients-with-acute-necrotizing-pancreatitis
#12
JOURNAL ARTICLE
Nan Liu, Yidong Wan, Yifan Tong, Jie He, Shufeng Xu, Xi Hu, Chen Luo, Lei Xu, Feng Guo, Bo Shen, Hong Yu
BACKGROUND: Persistent organ failure (POF) is the leading cause of death in patients with acute necrotizing pancreatitis (ANP). Although several risk factors have been identified, there remains a lack of efficient instruments to accurately predict the incidence of POF in ANP. METHODS: Retrospectively, the clinical and imaging data of 178 patients with ANP were collected from our database, and the patients were divided into training ( n = 125) and validation ( n = 53) cohorts...
2023: Gastroenterology Research and Practice
https://read.qxmd.com/read/37455363/increased-incidence-and-reduced-mortality-after-first-attack-of-acute-pancreatitis-over-an-18-year-period
#13
JOURNAL ARTICLE
O Vinge-Holmquist, Jūratė Šaltytė Benth, E Arnø, O Langbach, O Røkke
AIMS: To determine time trends in the incidence and etiology of acute pancreatitis and identify predictors for in-hospital mortality. PATIENTS AND METHODS: Retrospective study of 1722 patients with acute pancreatitis admitted to Akershus University Hospital between January 2000 and December 2017. Data were obtained from electronic patient files and computed tomography scans. We estimated a logistic regression model to assess differences in associations between patient characteristics and in-hospital mortality in two time periods, 2000-2009 (first period) and 2010-2018 (second period)...
July 16, 2023: Scandinavian Journal of Gastroenterology
https://read.qxmd.com/read/37217844/the-impact-of-multi-drug-resistant-pseudomonas-aeruginosa-infections-on-acute-pancreatitis-patients
#14
JOURNAL ARTICLE
Di Wu, Wenjun Lu, Yilin Huang, Ge Qin, Huanmiao Liu, Jie Xiao, Jie Peng
INTRODUCTION: Acute pancreatitis (AP) accounts for a high proportion of digestive diseases worldwide and has a high risk of infection. Pseudomonas aeruginosa, a common pathogen of hospital infections, has been observed to increase the resistance rate to several antibiotics, causing difficulties in treatments. Our study aims to investigate the impact of the multi-drug resistant Pseudomonas aeruginosa (MDR-PA) infections on AP patients. METHODS: At two Chinese tertiary referral centers for AP patients infected with MDR-PA, a retrospective case-control study with a 1:2 case-control ratio was performed...
May 22, 2023: BMC Infectious Diseases
https://read.qxmd.com/read/37172007/propofol-associated-hypertriglyceridemia-in-adults-with-acute-respiratory-distress-syndrome-on-extracorporeal-membrane-oxygenation
#15
JOURNAL ARTICLE
Sara Stallworth, Kelsey Ohman, Jennifer Schultheis, Alice Parish, Alaattin Erkanli, Heewon Kim, Craig R Rackley
The incidence and risk factors for propofol-associated hypertriglyceridemia (HTG) in patients receiving extracorporeal membrane oxygenation (ECMO) have not been evaluated. The purpose of this study was to determine the incidence and risk factors for propofol-associated HTG in patients with acute respiratory distress syndrome (ARDS) on ECMO. This retrospective, cohort study included 167 adults admitted to a medical intensive care unit (ICU) from July 1, 2013 to September 1, 2021, who received 24 hours of concurrent propofol and ECMO therapy...
May 10, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/36986350/pancreatic-necrosis-infection-as-a-determinant-of-multiple-organ-failure-and-mortality-in-acute-pancreatitis
#16
JOURNAL ARTICLE
Igor A Kryvoruchko, Valeriy V Boyko, Massimo Sartelli, Yulia V Ivanova, Denys O Yevtushenko, Andrij S Honcharov
Several recommendations and data on the treatment of acute necrotizing pancreatitis (ANP) are conflicting and different surgical approaches continue to exist. We conducted a study on 148 patients with ANP, who were divided into two groups: the main group ( n = 95) when the tactics of the step-up approach were applied with the principles of the concept of Enhanced Recovery After Surgery (ERAS) in order to determine this approach on effectiveness in reducing complications and 30-day mortality (2017-2022); the comparison group ( n = 53) when the same tactic of the treatment was used without ERAS principles (2015-2016)...
March 8, 2023: Pathogens
https://read.qxmd.com/read/36892797/incidence-and-outcomes-of-pancreatic-encephalopathy-in-patients-with-acute-pancreatitis-a-systematic-review-and-meta-analysis
#17
REVIEW
Yao Meng, Xiaojie Zheng, Fangbo Gao, Lan Chen, Jing Qiu, Hongyu Li, Xingshun Qi
Pancreatic encephalopathy (PE) is a lethal complication of acute pancreatitis (AP), but its clinical characteristics and prognosis remain obscure. Herein, we performed a systematic review and meta-analysis to evaluate the incidence and outcomes of PE in AP patients. PubMed, EMBASE, and China National Knowledge Infrastructure were searched. Based on the data from cohort studies, the incidence and mortality of PE in AP patients were pooled. Based on the individual data from case reports, logistic regression analyses were performed to identify the risk factors for death in PE patients...
March 9, 2023: Internal and Emergency Medicine
https://read.qxmd.com/read/36842549/-not-available
#18
JOURNAL ARTICLE
Jean Félix Piñerúa-Gonsálvez, María Lourdes Ruiz-Rebollo, Rosanna Del Carmen Zambrano-Infantino, María Antonella Rizzo-Rodríguez, Luis Fernández-Salazar
INTRODUCTION: Acute pancreatitis is a frequent inflammatory gastrointestinal disorder with high mortality rates in severe forms. An early evaluation of its severity is key to identify high-risk patients. This study assessed the influence of waist circumference together with hypertriglyceridemia on the severity of acute pancreatitis. METHODS: A retrospective study was performed, which included patients admitted with acute pancreatitis from March 2014 to March 2021...
February 24, 2023: Gastroenterología y Hepatología
https://read.qxmd.com/read/36830858/lactated-ringer-s-solution-reduces-severity-mortality-systemic-and-local-complications-in-acute-pancreatitis-a-systematic-review-and-meta-analysis
#19
REVIEW
Klementina Ocskay, Péter Mátrai, Péter Hegyi, Andrea Párniczky
Fluid therapy is the cornerstone of early supportive therapy in acute pancreatitis (AP). Regrettably, the type of fluid is still debated among clinicians, despite recent evidence from randomized controlled trials (RCTs). We aimed to incorporate all evidence from RCTs comparing lactated Ringer's solution (LR) with normal saline (NS) in adult and pediatric AP patients, with particular emphasis on clinically relevant outcomes. We evaluated RCTs comparing intravenous fluid resuscitation with LR to NS in adult or pediatric AP patients according to a prospectively registered protocol (CRD42021224542)...
January 23, 2023: Biomedicines
https://read.qxmd.com/read/36781508/efficacy-and-safety-of-early-enteral-and-intravenous-fluid-resuscitation-in-severe-acute-pancreatitis-a-systematic-review-and-meta-analysis
#20
JOURNAL ARTICLE
Jiao Liu, Huifang Qiu, Yanfang Yuan, Chengjiang Liu, Shaojian Mo, Fang He, Xifeng Fu
OBJECTIVE: To compare the efficacy and safety of enteral fluid resuscitation (via nasointestinal tube or colorectal tube) and intravenous fluid resuscitation (via intravenous route) in the early treatment of severe acute pancreatitis. METHODS: In this study, 8 electronic databases (PubMed, Web of Science, Embase, Cochrane Library, Scopus, China HowNet database, Wanfang database, and VIP database) were searched to collect clinical studies from inception to June 12, 2022...
February 13, 2023: International Journal of Colorectal Disease
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