Read by QxMD icon Read

Dysphagia head neck tumors treatment

Sara Fredslund Hajdú, Malene Bæk Christensen, Marlene Østermark Kristensen, Irene Wessel, Christoffer Johansen, Susanne Dalton
BACKGROUND: In recent years, preventive swallowing exercises have been investigated as a means to limit dysphagia in head and neck cancer patients. However, adherence to exercise regimes has been poorly documented limiting the conclusions drawn on the effects of the interventions. We investigated adherence to a preventive swallowing exercise program and identified possible associations between adherence and four selected baseline factors: HPV status, partner status, concomitant chemotherapy and tumor site and between adherence to swallowing exercises and attendance to supervised training sessions...
January 30, 2019: Acta Oncologica
Juliana Portas, Daniela Corrêa, Débora Queija, Lidia Maria Rebolho Batista Arantes, Luciano de Souza Viana, André Lopes Carvalho
Objective: To evaluate the effect of induction chemotherapy on swallowing and swallowing-related quality of life of patients with oropharyngeal, laryngeal and hypopharyngeal cancer. Study design: Prospective study of 33 patients with locally advanced tumors who were eligible for treatment with neoadjuvant chemotherapy followed by radiotherapy and concurrent chemotherapy. A multidimensional assessment of swallowing was performed using the following tools: (1) Clinical analysis, numerical scale for general pain and painful swallowing, American Speech and Hearing Association (ASHA) Functional Communication Measures (FCM) swallowing assessment scales, (2) assessment of Swallowing-Related Quality of Life (The MD Anderson Dysphagia Inventory - MDADI), and (3) swallowing videofluoroscopy...
January 25, 2019: Asian Pacific Journal of Cancer Prevention: APJCP
Carla Cristina Gusmon-Oliveira, Yeda Mayumi Kuboki, Gustavo Andrade de Paulo, Marcelo Simas de Lima, Ricardo Sato Uemura, Bruno Costa Martins, Luciano Lenz Tolentino, Adriana Vaz Safatle-Ribeiro, Marco Aurelio Kulcsar, Ulysses Ribeiro, Fauze Maluf-Filho
Background: Management of pharyngoesophageal stenosis (PES) in patients after head and neck cancer (HNC) treatment remains a challenge. It is not uncommon that PES is refractory to dilation sessions. This study aimed at evaluating the efficacy of Mitomycin C (MMC) endoscopic injection for the treatment of refractory pharyngoesophageal stenosis. Patients and methods: This is a prospective study in patients with dysphagia following head and neck cancer treatment, without evidence suggestive of tumor recurrence, and refractory to endoscopic treatment...
2018: Gastroenterology Research and Practice
Stephan Maring, Khaled Elsayad, Markus Stenner, Claudia Rudack, Uwe Haverkamp, Jan Rehkämper, Eva Wardelmann, Hans T Eich
BACKGROUND: Cisplatin-based chemotherapy (CTX) is commonly used concurrently with radiotherapy for head and neck cancer. The value of CTX regimens other than cisplatin for locally advanced squamous cell carcinoma of head and neck (LASCCHN) has not been well established. Here we compare the outcome of patients treated with different platinum-based chemotherapy regimens. METHODS: Medical records from 104 patients with LASCCHN treated with radiochemotherapy (RCTX) between February 2013 and August 2016 were analyzed...
2018: Oncology Research and Treatment
S Shahi, Anupam Raj Upadhyay, Anuj Devkota, Tridip Pantha, Dipendra Gautam, Dhundi Raj Paudel
INTRODUCTION: Carotid body tumors also known as parganglioma or chemodactomas are one of the rare tumors of head and neck which present as slow growing masses in the neck region. We present a case of 40 years female with painless slow growing mass over left side of her neck for 6 months. Diagnosis was made on basis of clinical history, examination and radiological findings. Tumor was graded as Shamblin grade II. She was managed with excision of the tumor without preoperative embolisation...
October 25, 2018: International Journal of Surgery Case Reports
Karl R Aigner, Emir Selak, Kornelia Aigner
PURPOSE: Head and neck cancer treatment achieves good locoregional tumor control rates while causing severe side effects. Therapy with chemotherapeutic drugs administered intravenously is limited because either the concentrations at the tumor site are too low or the total dosages are too high. The evaluation of a technique for short-term intra-arterial infusion chemotherapy is described herein. METHODS: In a retrospective study, we reviewed the medical records of 97 patients with head and neck cancers who received short-term intra-arterial infusion chemotherapy (62 patients previously untreated, 35 patients with prior radiotherapy)...
October 31, 2018: Journal of Cancer Research and Clinical Oncology
Ilya Likhterov, Meng Ru, Cindy Ganz, Mark L Urken, Raymond Chai, Devin Okay, Jerry Liu, Robert Stewart, Bruce Culliney, Daisy Palacios, Cathy L Lazarus
OBJECTIVES/HYPOTHESIS: This study examined saliva weight over time and its association with diet and patient-rated swallowing, dry mouth, sticky saliva, and dysgeusia quality of life in head and neck cancer (HNCA) patients treated with surgery plus adjuvant chemoradiotherapy (CRT), or primary CRT. STUDY DESIGN: Prospective cohort study in an outpatient HNCA center setting. METHODS: Patients were seen pretreatment, and 1, 3, 6, 12, 24, and 36 + months post-treatment...
October 16, 2018: Laryngoscope
Anna Rzepakowska, Ewa Osuch-Wójcikiewicz, Zuzanna Krupa, Aneta Durmaj, Kazimierz Niemczyk
INTRODUCTION: Parapharyngeal space (PPS) is the anatomical area lateral to the upper pharynx and clinically important due to PPS tumors. They account for less than 1% of head and neck neoplasms. Both benign and malignant neoplasms may arise there and typical for this localization is diversity of histological origin. Complete surgical excision is still the basis of treatment. AIM OF THE STUDY: Evaluation of the results of surgical treatment of PPS tumors in the Department of Otolaryngology at the Medical University over the period 2015-2017...
May 16, 2018: Otolaryngologia Polska
Douglas Adkins, Paul Mehan, Jessica Ley, Marilyn J Siegel, Barry A Siegel, Farrokh Dehdashti, Xuntian Jiang, Noha N Salama, Kathryn Trinkaus, Peter Oppelt
BACKGROUND: Angiogenesis is a hallmark of head and neck squamous cell carcinoma (HNSCC), and a mechanism of resistance to EGFR inhibition. We investigated the safety and potential activity of pazopanib, an angiogenesis inhibitor, plus cetuximab, an EGFR inhibitor, in patients with recurrent or metastatic HNSCC. METHODS: We did an open-label, single-centre, dose-escalation phase 1b trial using a standard 3 + 3 design, followed by an expansion cohort phase. Eligible participants were patients with histologically or cytologically confirmed recurrent or metastatic HNSCC, aged at least 18 years, had measurable disease as per Response Evaluation Criteria in Solid Tumors (RECIST) version 1...
August 2018: Lancet Oncology
Alexis Lopez, Anton M Kushnaryov, Robert A Weisman
Head and neck sarcomas are rare and consist of a variety of histologic subtypes. We present a case of undifferentiated/unclassified sarcoma (UUS) of the maxillary sinus, a tumor subtype historically known as malignant fibrous histiocytoma (MFH) or undifferentiated pleomorphic sarcoma (UPS). A 50-year-old female patient presented with worsening facial pain and dysphagia. Physical examination demonstrated a large, ulcerated mass protruding from the oral cavity. Computed tomography demonstrated a large, enhancing mass centered in the right maxillary sinus with local invasion...
April 2018: Ear, Nose, & Throat Journal
Petra Ambrosch, Mireia Gonzalez-Donate, Asita Fazel, Claudia Schmalz, Jürgen Hedderich
Introduction: Transoral laser microsurgery (TLM) is an accepted and effective treatment strategy for supraglottic carcinomas. Early supraglottic carcinoma has excellent outcomes independently of the treatment approach. The role of TLM for the treatment of locally advanced tumors is debated. Particularly, the functional outcomes after TLM have to be proven by functional assessment of large cohorts of patients. This study analyzes the oncologic and functional outcomes after TLM for supraglottic carcinomas...
2018: Frontiers in Oncology
Amit Bahl, Arun Singh Oinam, Arun Elangovan, Satinder Kaur, Gaurav Trivedi, Roshan Verma, Sudhir Bhandari, Sushmita Ghoshal, Naresh Kumar Panda
Objectives: Locoregional recurrence is the predominant pattern of treatment failure in advanced head and neck cancers. Reirradiation is a useful modality to treat inoperable head and neck cancer patients with recurrent disease. The aim of the present study was to analyze the treatment toxicity and early clinical outcomes in patients undergoing reirradiation. Methods: Twenty patients of head and neck cancers with recurrences or second cancers were evaluated. Reirradiation was done using simultaneous integrated boost volumetric modulated arc therapy (SIB VMAT), intensity modulated radiotherapy (IMRT), or conventional radiotherapy using 6MV photons...
2018: Journal of Oncology
David Forner, Derek Wilke, Matthew H Rigby, Sidney Croul, Anuradha Mishra, Emad Massoud, David B Clarke, Nathan Lamond
BACKGROUND: HPV-associated OSCC (HPV-OSCC) has been determined to be a distinct disease entity from non-HPV associated OSCC. Patients affected by HPV-OSCC generally have a more favourable prognosis, with improved rates of locoregional control and survival compared with their non-HPV counterparts. Despite this, HPV-OSCC has a similar rate of distant metastases. Interestingly, recent evidence has emerged that demonstrates more frequent atypical metastasis patterns when compared to non-HPV associated disease...
May 9, 2018: Journal of Otolaryngology—Head & Neck Surgery
Ralph Muecke, Oliver Micke, Lutz Schomburg, Jens Buentzel, Klaus Kisters, Irenaeus A Adamietz
Introduction: Se measurement and supplementation in radiation oncology is a controversial issue. The German Working Group Trace Elements and Electrolytes in Oncology (AKTE) has conducted a number of studies on this issue, which are summarized in this review. Strategies have been tested and developed, aiming to stratify the patients with a potential need for supplemental Se and how best to monitor Se supplementation with respect to health effects and risks. Methods: We analyzed blood and tissue Se-levels of different tumor patients ( n = 512)...
April 13, 2018: Nutrients
Julie Schatteman, Dirk Van Gestel, Dieter Berwouts, Werner De Gersem, Geert De Kerf, Wilfried De Neve, Bie De Ost, Ana Maria Luiza Olteanu, Sylvie Rottey, Tom Vercauteren, Ingeborg Goethals, Fréderic Duprez
PURPOSE: To evaluate feasibility, disease control, survival, and toxicity after adaptive 18 F-fluorodeoxyglucose (FDG) positron emisson tomography (PET) guided radiotherapy in patients with recurrent and second primary head and neck squamous cell carcinoma. METHODS: A prospective trial investigated the feasibility of adaptive intensity modulated radiotherapy (IMRT) ± concomitant cetuximab in 10 patients. The primary endpoint was achieving a 2-year survival free of grade >3 toxicity in ≥30% of patients...
August 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Harish Dharmarajan, Noémie Rouillard-Bazinet, Binoy M Chandy
INTRODUCTION: Pediatric head and neck teratomas account for less than 4% of congenital teratomas. The distinct presentations and outcomes of mature and immature head and neck teratomas have not been well established. OBJECTIVES: To review the management and outcomes of pediatric head and neck teratomas. To distinguish differences between mature and immature tumors with respect to the age at presentation and surgery, tumor size and location, alpha fetoprotein (AFP) levels, airway management, and recurrence...
February 2018: International Journal of Pediatric Otorhinolaryngology
Mydhili Mayadevi, Krishnakumar Thankappan, Shashikant Vishnubhai Limbachiya, Sivakumar Vidhyadharan, Brenda Villegas, Melody Ouyoung, Deepak Balasubramanian, Jayakumar R Menon, Uttam Sinha, Subramania Iyer
The study considered the feasibility and impact of interdisciplinary telemedicine discussions in the management of post-treatment dysphagia in patients with head and neck tumors. This is a retrospective analysis of patients with persistent dysphagia after treatment for head and neck pathology, at an institute in India. The cases were discussed in the telemedicine meeting conducted between host institute and a second unit in the United States. A monthly meeting was organized, using an internet-based video conference system...
August 2018: Dysphagia
Jenna Sitenga, Gregory Aird, Adam Vaudreuil, Christopher J Huerter
Head and neck schwannomas comprise 25-40% of all schwannomas, with presentation on the lips as the rarest and most surgically complicated site for perioral tumors. A systematic literature review was conducted to include 21 cases of patients with schwannoma of the upper or lower lips. The majority of patients presented with a single, painless, well-encapsulated nodule on the upper or lower lips. The nodules were consistently slow-growing, with an average 29.3 months from symptom onset to clinical presentation...
September 2018: International Journal of Dermatology
James S Metkus, David Cognetti, Joseph Curry
Objectives: Head and neck cancer (HNC) patients often require percutaneous gastrostomy (PEG) tube placement due to malnutrition and dysphagia. While beneficial, PEG tube placement can cause a rare but reportable complication of metastasis of the original tumor to the gastrostomy exit site. The objectives of this case series were to present HNC patients at a single institution that developed PEG tube metastases, their subsequent treatment, and review of the literature for similar cases...
December 2017: Laryngoscope Investigative Otolaryngology
Daniel Mirea, Liliana Elena Mirea, Cornelia Nitipir, Mirela Ţigliş, Ioana Cristina GrinŢescu, Tiberiu Paul Neagu, Carmen Aurelia Mogoantă, Ioana Marina GrinŢescu
The extranodal malignant lymphomas occur mainly in the region of the head and neck, after the gastrointestinal tract. The most common site of the head and neck lymphoma is at the lymphatics ring of Waldeyer, followed by the nasosinusal region. Localization at the base of the tongue is extremely rare. The authors reported a case of a 50-year-old male with a non-Hodgkin's lymphoma, which developed at the base of tongue. An unusual sensation described as a foreign body at the hypopharyngeal region associated with progressive dysphagia were the main symptoms for which the patient was referred to our Hospital...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"