Pieter Evenepoel, Hanne Skou Jørgensen, Jordi Bover, Andrew Davenport, Justine Bacchetta, Mathias Haarhaus, Ditte Hansen, Carolina Gracia-Iguacel, Markus Ketteler, Louise McAlister, Emily White, Sandro Mazzaferro, Marc Vervloet, Rukshana Shroff
Mineral and bone disorders (MBD) are common in patients with chronic kidney disease (CKD), contributing to significant morbidity and mortality. For several decades, the first-line approach to control hyperparathyroidism in CKD was by exogenous calcium loading. Since the turn of the millennium, however, a growing awareness of vascular calcification risk has led to a paradigm shift in management and a move away from calcium-based phosphate binders. As a consequence, contemporary CKD patients may be at risk of a negative calcium balance, which, in turn, may compromise bone health, contributing to renal bone disease and increased fracture risk...
September 11, 2023: Nephrology, Dialysis, Transplantation