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Keywords Group B streptococcal neonatal...

Group B streptococcal neonatal infection

https://read.qxmd.com/read/36404044/imaging-of-congenital-childhood-central-nervous-system-infections
#21
REVIEW
Tang Phua Hwee, Thoon Koh Cheng
This article highlights the changing profile of the pediatric patient with central nervous system infection as countries develop and the roles of different imaging modalities such as cranial ultrasound, MR imaging, and computed tomography. It discusses the commonly encountered congenital toxoplasmosis, rubella, cytomegalovirus, herpes simplex (TORCH) infections, Group B Streptococcal and Escherichia coli infections in the neonatal period, and disease outbreaks affecting children. Iatrogenic, opportunistic, and immune-mediated changes as well as long-term effects of infection and mimics of infection are also discussed...
February 2023: Neuroimaging Clinics of North America
https://read.qxmd.com/read/36383285/increased-risk-of-group-b-streptococcal-sepsis-and-meningitis-in-hiv-exposed-uninfected-infants-in-a-high-income-country
#22
JOURNAL ARTICLE
Á Manzanares, L M Prieto-Tato, L Escosa-García, M Navarro, S Guillén, M Penin, A Hernanz-Lobo, B Soto-Sánchez, J Beceiro-Mosquera, I Falces-Romero, J T Ramos-Amador, M Á Orellana-Miguel, C Epalza
The purpose of this study is to compare group B Streptococcus (GBS) infection incidence in HIV-exposed uninfected (HEU) and HIV-unexposed (HU) infants in a Spanish cohort. We conducted a retrospective study in 5 hospitals in Madrid (Spain). Infants ≤ 90 days of life with a GBS infection were included from January 2008 to December 2017. Incidence of GBS infection in HEU and HU children was compared. HEU infants presented a sevenfold greater risk of GBS infection and a 29-fold greater risk of GBS meningitis compared to HU, with statistical significance...
November 16, 2022: European Journal of Pediatrics
https://read.qxmd.com/read/36374063/-streptococcus-agalactiae-late-onset-infection-associated-with-human-milk-three-cases-report
#23
Guadalupe Albornoz Crespo, Guadalupe Alda, Liliana Vázquez, Néstor E Vain, Ana Pedraza
Group B β-hemolytic Streptococcus or Streptococcus agalactiae is a major cause of morbidity and mortality in neonates, especially in premature infants. Current prevention strategies have been effective in reducing the frequency of early onset neonatal sepsis caused by vertical transmission. The incidence of late onset sepsis due to this microorganism has not changed and the route of infection is less clear. In breastfed infants, transmission through breast milk is possible. We report three cases of late group B β-hemolytic streptococcal infection in breastfed preterm infants whose mothers had mastitis...
December 2022: Archivos Argentinos de Pediatría
https://read.qxmd.com/read/36241341/sogc-guideline-retirement-notice-no-2
#24
JOURNAL ARTICLE
(no author information available yet)
These documents have been archived because they contain outdated information. They should not be consulted for clinical use, but for historical research only. Please visit the journal website for the most recent guidelines. The Use of Magnetic Resonance Imaging in the Obstetric Patient [J Obstet Gynaecol Can 36 (2014) 349-355] AUTHORS Yves Patenaude, MD, Sherbrooke, QC Denise Pugash, MD, Vancouver, BC Kenneth Lim, MD, Vancouver, BC Lucie Morin, MD, Montreal, QC The Role of Surgery in Endometrial Cancer [J Obstet Gynaecol Can 35 (2013) 370-371] AUTHORS Christopher Giede, MD, Saskatoon, SK Tien Le, MD, Ottawa, ON Patti Power, MD, St John's, NL Female Genital Cutting [J Obstet Gynaecol Can 35 (2013) 1028-1045] AUTHORS Liette Perron, MSW, Ottawa, ON Vyta Senikas, MD, Ottawa, ON Margaret Burnett, MD, Winnipeg, ON Victoria Davis, MD, Scarborough, ON Technical Update on Pessary Use [J Obstet Gynaecol Can 35 (2013) 664-674] AUTHORS Magali Robert, MD, Calgary, AB Jane A...
October 2022: Journal of Obstetrics and Gynaecology Canada: JOGC
https://read.qxmd.com/read/36215812/ameliorating-adverse-perinatal-outcomes-with-lactoferrin-an-intriguing-chemotherapeutic-intervention
#25
REVIEW
Julie A Talbert, Jacky Lu, Sabrina K Spicer, Rebecca E Moore, Steven D Townsend, Jennifer A Gaddy
Adverse pregnancy outcomes affect 54 million people globally per year, with at least 50% of these attributed to infection during gestation. These include inflammation of the membranes surrounding the growing fetus (chorioamnionitis), preterm prelabor rupture of membranes (PPROM), preterm birth (PTB), early-onset disease (EOD) and late-onset disease (LOD), neonatal and maternal sepsis, and maternal or fetal demise. Although universal screening and implementation of intrapartum antibiotic prophylaxis (IAP) has improved EOD outcomes, these interventions have not reduced the incidences of LOD or complications occurring early on during pregnancy such as PPROM and PTB...
September 29, 2022: Bioorganic & Medicinal Chemistry
https://read.qxmd.com/read/36069447/the-group-b-streptococcal-adhesin-bspc-interacts-with-host-cytokeratin-19-to-promote-colonization-of-the-female-reproductive-tract
#26
JOURNAL ARTICLE
Haider S Manzer, Dustin T Nguyen, Joo Youn Park, Nogi Park, Keun Seok Seo, Justin A Thornton, Angela H Nobbs, Kelly S Doran
Streptococcus agalactiae, otherwise known as Group B Streptococcus (GBS), is an opportunistic pathogen that vaginally colonizes approximately one third of healthy women. During pregnancy, this can lead to in utero infection, resulting in premature rupture of membranes, chorioamnionitis, and stillbirths. Furthermore, GBS causes serious infection in newborns, including sepsis, pneumonia, and meningitis. Previous studies have indicated that GBS antigen (Ag) I/II family proteins promote interaction with vaginal epithelial cells; thus, we hypothesized that the Ag I/II Group B streptococcal surface protein C (BspC) contributes to GBS colonization of the female reproductive tract (FRT)...
September 7, 2022: MBio
https://read.qxmd.com/read/36059918/group-b-streptococcus-a-pathogen-not-restricted-to-neonates
#27
JOURNAL ARTICLE
Birger Trollfors, Fredrik Melin, Margret Johansson Gudjonsdottir, Rebecca Rupröder, Milen Sandin, Mats Dahl, Johanna Karlsson, Erik Backhaus
Objectives: This was a retropective study of invasive group B streptococcal (GBS) infections isolated from blood, cerebrospinal fluid (CSF), synovial fluid, peritoneal fluid, pleural fluid, pericardial fluid and corpus vitreum in a defined region in southwest Sweden over a 14-year period. Design: Information on all invasive GBS infections was obtained from all four bacteriological laboratories in the region, with data obtained from individual patient records. Results: GBS was isolated from normally sterile body fluids in 1244 samples (579 from females and 665 from males) from 1101 patients...
September 2022: IJID Reg
https://read.qxmd.com/read/36004365/genetic-diversity-and-antimicrobial-resistance-of-invasive-noninvasive-and-colonizing-group-b-streptococcus-isolates-in-southern-brazil
#28
JOURNAL ARTICLE
Otto Henrique May Feuerschuette, Eduardo Venâncio Alves, Mara Cristina Scheffer, Ana Paula Pessoa Vilela, Fernando Hartmann Barazzetti, Henrique Miranda Feuerschuette, Ana Carolina Lobor Cancelier, Maria Luiza Bazzo
Introduction: Group B Streptococcus (GBS) is a human commensal bacterium that is also associated with infection in pregnant and non-pregnant adults, neonates and elderly people. Gap Statement: The authors hypothesize that knowledge of regional GBS genetic patterns may allow the use of prevention and treatment measures to reduce the burden of streptococcal disease. Aim: The aim was to report the genotypic diversity and antimicrobial sensitivity profiles of invasive, noninvasive urinary and colonizing GBS strains, and evaluate the relationships between these findings...
August 2022: Access microbiology
https://read.qxmd.com/read/35794077/evaluation-of-appropriate-vancomycin-prescribing-for-the-prevention-of-newborn-group-b-streptococcal-infections-in-a-community-hospital-obstetrics-service
#29
JOURNAL ARTICLE
Amirah Assabahi, Rita Driggers, Christopher A Keeys, Alexa Mader, Paul Norris
OBJECTIVES: The 2019 American College of Obstetricians and Gynecologists (ACOG) guidelines update for the prevention of perinatal group B Streptococcus (GBS) infections stipulate that vancomycin should be reserved to treat penicillin-allergic women at high risk for anaphylaxis with documented GBS resistance to clindamycin. Protocols and policies were adapted at the community hospital to incorporate these new guidelines. The primary objective of this research was to evaluate institutional compliance to these guidelines and secondarily, clinical outcomes...
November 25, 2022: Journal of Perinatal Medicine
https://read.qxmd.com/read/35693054/screening-of-group-b-streptococcus-infection-in-pregnancy-and-neonatal-outcomes-in-the-province-of-trento-italy
#30
JOURNAL ARTICLE
Silvano Piffer, Roberto Rizzello, Mariangela Pedron, Laura Dellanna, Anna Lina Lauriola
The study analyzes the trend of group B streptococcal (GBS) infection in pregnancy in the province of Trento, Italy, where a universal screening of GBS infection in pregnancy has been active for some time. Data from pregnant women who gave birth at local maternity units between 2015-2019 were obtained from birth attendance certificates (BAC), the main - and mandatory - source of information for monitoring pregnancies, births and neonatal health in Italy. The BAC used in the province of Trento acquires the results of a vast range of infections in pregnancy...
2022: Le Infezioni in Medicina
https://read.qxmd.com/read/35658538/genomic-analyses-identify-manganese-homeostasis-as-a-driver-of-group-b-streptococcal-vaginal-colonization
#31
JOURNAL ARTICLE
Lindsey R Burcham, Madeline S Akbari, Norhan Alhajjar, Rebecca A Keogh, Jana N Radin, Thomas E Kehl-Fie, Ashton T Belew, Najib M El-Sayed, Kevin S McIver, Kelly S Doran
Group B Streptococcus (GBS) is associated with severe infections in utero and in newborn populations, including pneumonia, sepsis, and meningitis. GBS vaginal colonization of the pregnant mother is an important prerequisite for transmission to the newborn and the development of neonatal invasive disease; however, our understanding of the factors required for GBS persistence and ascension in the female reproductive tract (FRT) remains limited. Here, we utilized a GBS mariner transposon ( Krmit ) mutant library previously developed by our group and identified underrepresented mutations in 535 genes that contribute to survival within the vaginal lumen and colonization of vaginal, cervical, and uterine tissues...
June 6, 2022: MBio
https://read.qxmd.com/read/35633256/progress-in-diagnosis-and-treatment-of-neonatal-sepsis-a-review-article
#32
REVIEW
Pratibha Yadav, Shailendra Kumar Yadav
UNLABELLED: Neonatal sepsis is a serious condition in which the pathogens infiltrate the bloodstream, multiply and produce toxins causing deleterious effects to the health of neonates. It is divided into two types on the basis of the time of onset. Early onset sepsis occurs within 72 hours of birth and late onset sepsis begins after 72 hours of delivery. Neonatal sepsis continues to be a common and significant health care burden, especially in very low birth weight infants (with birthweight less than 1500 grams)...
March 11, 2022: JNMA; Journal of the Nepal Medical Association
https://read.qxmd.com/read/35552426/group-b-streptococcal-cellulitis-adenitis-syndrome-in-infants-insights-from-24-years-of-experience
#33
JOURNAL ARTICLE
Ana Del Valle Penella, Christopher C Pretorius, Carol J Baker, Marcia A Rench, Catherine Mary Healy, Morven S Edwards
This series of 28 infants with group B streptococcal (GBS) cellulitis-adenitis from a single institution over 24 years offers insights important to the early recognition, spectrum of findings, and optimal management of this rare manifestation of invasive GBS disease.
May 10, 2022: Journal of the Pediatric Infectious Diseases Society
https://read.qxmd.com/read/35438474/group-b-streptococcal-colonization-among-pregnant-women-and-neonates-in-a-tertiary-care-hospital-in-south-india
#34
JOURNAL ARTICLE
Lakshmi M Warrier, Sapna Joy, Raja Rajeswari C, Rani Ameena Bashir
OBJECTIVES: To assess the prevalence of maternal and neonatal group B Streptococcal colonization, incidence of neonatal systemic illness, and antibiotic sensitivity of isolates. METHODS: This prospective cohort study was conducted in a South Indian tertiary care hospital. Rectovaginal swabs from pregnant mothers at 360/7 -376/7 wk gestation and throat and rectal swabs from their neonates at 48 h of age were collected. Presence of group B Streptococcus (GBS) was identified by broth enrichment step, and traditional microbiologic methods and antibiotic sensitivity of isolates was noted...
April 19, 2022: Indian Journal of Pediatrics
https://read.qxmd.com/read/35404292/epidemiological-evolution-of-early-onset-neonatal-sepsis-over-12-years-a-single-center-population-based-study-in-central-taiwan
#35
JOURNAL ARTICLE
I-Chun Lu, Yu-Chia Chang, Yin-Ting Chen, Hsiang-Yu Lin, Hsiao-Yu Chiu, Ming-Luen Tsai, Hung-Chih Lin
BACKGROUND: We aimed to explore the epidemiology and evolution of pathogens, antibiotic susceptibility, and mortality rate in cases of neonatal early-onset sepsis (EOS) reported over a period of 12 years in a level III neonatal center in Central Taiwan. METHODS: Patients' medical records in a neonatal center from 2007 to 2018 were reviewed to obtain information on infants with culture-proven EOS, which included pathogens found in the blood or cerebrospinal fluid cultures...
2022: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/35334420/reduction-of-intrapartum-antibiotic-prophylaxis-by-combining-risk-factor-assessment-with-a-rapid-bedside-intrapartum-polymerase-chain-reaction-testing-for-group-b-streptococci
#36
JOURNAL ARTICLE
C M Hartvigsen, S Y Nielsen, J K Møller, M R Khalil
OBJECTIVE: To investigate the impact of administering Intrapartum Antibiotic Prophylaxis (IAP) to laboring women with one or more risk factors for Early Onset Group B Streptococcal neonatal infection (EOGBS) based on the result of a rapid bedside test for Group B Streptococci (GBS). STUDY DESIGN: Quality assessment study. METHODS: Three-hundred-sixty-six laboring women admitted to our maternity ward, with one or more risk factors for EOGBS, were prospectively included...
May 2022: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/35323895/group-b-streptococcal-infection-in-extremely-preterm-neonates-and-neurodevelopmental-outcomes-at-2-years
#37
JOURNAL ARTICLE
Karen M Puopolo, Sagori Mukhopadhyay, Nellie I Hansen, Dustin D Flannery, Rachel G Greenberg, Pablo J Sanchez, Edward F Bell, Sara B DeMauro, Myra H Wyckoff, Eric C Eichenwald, Barbara J Stoll
BACKGROUND: Determine the incidence of GBS disease among extremely preterm infants and assess risk of death or neurodevelopmental impairment (NDI) at 18-26 months' corrected age. METHODS: Observational cohort study of infants enrolled in a multicenter registry. GBS disease incidence was assessed in infants born 1998-2016 at 22-28 weeks' gestation surviving >12 hours. The composite outcome, death or NDI, was assessed in infants born 1998-2014 at 22-26 weeks' gestation...
March 22, 2022: Clinical Infectious Diseases
https://read.qxmd.com/read/35316308/targeting-the-bspc-vimentin-interaction-to-develop-anti-virulence-therapies-during-group-b-streptococcal-meningitis
#38
JOURNAL ARTICLE
Haider S Manzer, Ricardo I Villarreal, Kelly S Doran
Bacterial infections are a major cause of morbidity and mortality worldwide and the rise of antibiotic resistance necessitates development of alternative treatments. Pathogen adhesins that bind to host cells initiate disease pathogenesis and represent potential therapeutic targets. We have shown previously that the BspC adhesin in Group B Streptococcus (GBS), the leading cause of bacterial neonatal meningitis, interacts with host vimentin to promote attachment to brain endothelium and disease development. Here we determined that the BspC variable (V-) domain contains the vimentin binding site and promotes GBS adherence to brain endothelium...
March 2022: PLoS Pathogens
https://read.qxmd.com/read/35027057/rapid-intrapartum-test-for-maternal-group-b-streptococcal-colonisation-and-its-effect-on-antibiotic-use-in-labouring-women-with-risk-factors-for-early-onset-neonatal-infection-gbs2-cluster-randomised-trial-with-nested-test-accuracy-study
#39
RANDOMIZED CONTROLLED TRIAL
Jane P Daniels, Emily Dixon, Alicia Gill, Jon Bishop, Mark Wilks, Michael Millar, Jim Gray, Tracy E Roberts, Jane Plumb, Jonathan J Deeks, Karla Hemming, Khalid S Khan, Shakila Thangaratinam
BACKGROUND: Mother-to-baby transmission of group B Streptococcus (GBS) is the main cause of early-onset infection. We evaluated whether, in women with clinical risk factors for early neonatal infection, the use of point-of-care rapid intrapartum test to detect maternal GBS colonisation reduces maternal antibiotic exposure compared with usual care, where antibiotics are administered due to those risk factors. We assessed the accuracy of the rapid test in diagnosing maternal GBS colonisation, against the reference standard of selective enrichment culture...
January 14, 2022: BMC Medicine
https://read.qxmd.com/read/34959562/group-b-streptococcal-colonization-in-african-countries-prevalence-capsular-serotypes-and-molecular-sequence-types
#40
REVIEW
Sarah Shabayek, Patricia Ferrieri, Barbara Spellerberg
Streptococcus agalactiae or group B streptococcus (GBS) is a commensal of the gastrointestinal and genitourinary tracts of healthy women and an important cause of neonatal invasive infections worldwide. Transmission of bacteria to the newborn occurs at birth and can be prevented by intrapartum antibiotic prophylaxis. However, this not available in resource limited settings in Africa, which carries a particular high burden of disease. Serotype based vaccines are in development and present a suitable alternative to prevent neonatal infections...
December 10, 2021: Pathogens
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