Mina Mohammadi, Samin Abbaszadeh, Vahideh Nosrati-Siahmazgi, Mahsa Akbari, Saman Rezaei, Kiyan Musaie, Mohammad Reza Eskandari, Hélder A Santos, Narges Poursina, Mohammad-Ali Shahbazi
Bone tissue engineering (BTE) involves the design of three-dimensional (3D) scaffolds that aim to address current challenges of bone defect healing, such as limited donor availability, disease transmission risks, and the necessity for multiple invasive surgeries. Scaffolds can mimic natural bone structure to accelerate the mechanisms involved in the healing process. Herein, a crosslinked combination of biopolymers, including gelatin (GEL), chitosan (CS), and hyaluronic acid (HA), loaded with diatom (Di) and β-sitosterol (BS), is used to produce GCH-Di-S scaffold by freeze-drying method...
February 29, 2024: Heliyon