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I I Lisina, О S Vaulina, Е А Lisin
The conditions for the amplitude instability onset in a two-dimensional Yukawa cluster system consisting of seven particles are investigated for the case of sufficiently large thermal particle displacements. We consider here an analytical approach to derive the criterion for such instability onset, which is based on searching an energetically favorable inflection point of the system potential energy. We show that there is a proportionality between melting curve for an "infinite" two-dimensional system with the hexagonal lattice and analytical curve of critical points for the seven-particle Yukawa cluster...
January 2019: Physical Review. E
L P Sycheva, R A Shchegoleva, N I Lisina, A V Gordeev, L M Rozhdestvenskii
We studied the mutagenic effect of X-ray irradiation in doses of 0.5, 1, and 1.5 Gy on female (CBA×C57Bl/6)F1 mice. The mutagenic effect (assessed by the parameter "frequency of bone marrow polychromatophilic erythrocytes with micronuclei") linearly depended on the dose of X-ray irradiation in the range of up to 1 Gy and reached the plateau at 1.5 Gy. The fraction of polychromatophilic erythrocytes was 45, 45, and 46% under control conditions (without exposure) and exposure to the irradiation in the doses of 0...
November 2018: Bulletin of Experimental Biology and Medicine
V I Larkin, A A Bort, T A Lisina, A D Potasheva, V A Hvostov
AIM: To study an effect of comorbidity on the course and outcome of ischemic stroke (IS). MATERIAL AND METHODS: Results of a unicenter, retrospective, cohort study of 190 patients with ischemic stroke (IS) were analyzed. Severity of stroke, dependence in the daily activities, comorbidity were assessed using NIHSS, the Rankin scale,CCI, CIRS. RESULTS AND CONCLUSION: The correlation of IS severity and outcome with the severity of comorbid pathology assessed by CCI and CIRS was identified...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
A M Surin, R R Sharipov, I A Krasil'nikova, D P Boyarkin, O Yu Lisina, L R Gorbacheva, A V Avetisyan, V G Pinelis
The MTT assay based on the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium in the cell cytoplasm to a strongly light absorbing formazan is among the most commonly used methods for determination of cell viability and activity of NAD-dependent oxidoreductases. In the present study, the effects of MTT (0.1 mg/ml) on mitochondrial potential (ΔΨm), intracellular NADH, and respiration of cultured rat cerebellum neurons and isolated rat liver mitochondria were investigated. MTT caused rapid quenching of NADH autofluorescence, fluorescence of MitoTracker Green (MTG) and ΔΨm-sensitive probes Rh123 (rhodamine 123) and TMRM (tetramethylrhodamine methyl ester)...
June 2017: Biochemistry. Biokhimii︠a︡
I I Lisina, E A Lisin, O S Vaulina, O F Petrov
The liquid-crystal type of phase transition in complex plasmas has been observed repeatedly. However, more studies need to be done on the liquid-vapor transition in complex plasmas. In this paper, the phenomenon of coupling (condensation) of particles into self-confined particle pairs in an anisotropic plasma medium with ion flow is considered analytically and numerically using the Langevin molecular dynamics method. We obtain the stability conditions of the pair (bound) state depending on the interaction parameters and particle kinetic energy...
January 2017: Physical Review. E
Conceição Aparecida Dornelas, Alessandra Marques Dos Santos, Antonio Lucas Oliveira Correia, Camila de Carvalho Juanes, João Paulo Ferreira Coelho, Bianca Lopes Cunha, André Vinicius Vieira Maciel, Francisco Vagnaldo Fechine Jamacaru
OBJECTIVE: to evaluate the effect of L-lysine in the bladder and intestinal epithelia in rats submitted to vesicosigmoidostomy. METHODS: we divided forty Wistar rats into four groups: group I - control group (Sham); group II - submitted to vesicosigmoidostomy and treated with L-lysine 150mg/kg; group III - submitted only to vesicosigmoidostomy; and group IV - received L-lysine 150mg/kg. After eight weeks the animals were sacrificed. RESULTS: in the bladders of all operated animals we observed simple, papillary and nodular hyperplasia of transitional cells, transitional cell papillomas and squamous metaplasia...
March 2016: Revista do Colégio Brasileiro de Cirurgiões
L M Rozhdestvensky, V F Mikhailov, T G Schlyakova, J M Shagirova, R A Shchegoleva, N F Raeva, N I Lisina, L V Shulenina, V V Zorin, A V Pchelka, K Y Trubitsina
Different radiomodificators (cytokine betaleukine, antioxidant phenoxan, antigipoksant limontar and nucleoside riboxin) were investigated on mice for evaluating their radiation protective capacity against prolonged (21 h) exposure at a dose of 12.6 Gy at a low dose rate of 10 mGy/min. Bone marrow cellularity and endogenic CFUs were used as evaluation criteria 9 days after exposure. Simultaneously, expression of the heat shock proteins of 25, 70 and 90 kDa in unexposed mice bone marrow was studied 2, 24 and 48 h after injections...
July 2015: Radiatsionnaia Biologiia, Radioecologiia
Marija Mihajlović, Nebojša Perišić, Lato Pezo, Mirjana Stojanović, Jelena Milojković, Zorica Lopičić, Marija Petrović
This study examined the possibility of direct application of phosphate rock (PR) from Lisina deposit, in a mixture with natural clinoptilolite (Cp) and clinoptilolite partially saturated with ammonium ions (NH4-Cp). Solution P concentrations of the NH4-Cp/PR mixtures were sufficient for plant growth and ranged from 0.36 to 0.82 mg L(-1). The median NH4-Cp/PR ratio and the longest proposed mixing time had the most positive impact on the P concentration. Solution Ca concentrations of the NH4-Cp/PR mixtures were between 112...
October 15, 2014: Journal of Agricultural and Food Chemistry
L M Rozhdestvenskiĭ, T G Shliakova, R A Shchegoleva, N I Lisina, V V Zorin
Recombinant human thrombopoietin (rh TPO) has been investigated as a means of acute radiation disease urgent treatment in the experiments on 24 mongrel dogs. The animals were exposed to total acute gamma-irradiation at the doses of 3.5 Gy (exceeding LD50/45 under our conditions) and 3 Gy. All the dogs including control ones received antibiotics Ampicillin and Gentamicin twice a day during the acute period from the 7th to the 21st day. TPO was injected one time s/c or i/v at the doses of5 or 10 mkg/kg 1.5-2 h after exposure...
May 2013: Radiatsionnaia Biologiia, Radioecologiia
L M Rozhdestvenskiĭ, R A Shchegoleva, Iu B Deshevoĭ, N I Lisina, B A Titov
In the experiments on F1 (CBA x C57BL) and BALB mice irradiated by 137Cs gamma-rays, preparations of unglycosilated G-SCF such as Neupogen and their domestic analogs Leucostim and Neupomax were investigated. The tests such as 9-day bone marrow cellularity (BMC) and endogenous CFUs, the neutrophile number restoration, the 30-day survival index have shown that all three preparations have an approximately equal effectiveness relating to acute radiation disease treatment and granulopoiesis stimulation after a 5-10 day consecutive administration following irradiation of mice at lethal and sublethal doses...
September 2012: Radiatsionnaia Biologiia, Radioecologiia
Berta Escobar, Ana María Estévez, Carolina Fuentes, Daniela Venegas
Limiting amino acids of the protein from chilean "algarrobo" are isoleucine, theronine and methionine/cyteine. Cereals and legume blends allow to improve the amino acid balance, since legume have more lysine, and cereals are richer in sulphur amino acids. Due to the nutritional interest of "algarrobo" cotyledons, the use of "algarrobo cotyledon" flour (ACF) in sweet and salty snack manufacture was evaluated. Cookies and fried salty chips with 0%, 10% and 20% ACF were prepared. Flours were analyzed for color, particle size, moisture, proximate composition, available lysine, and soluble, insoluble and total dietary fiber...
June 2009: Archivos Latinoamericanos de Nutrición
V Z Lankin, M O Lisina, N E Arzamastseva, G G Konovalova, L V Nedosugova, A I Kaminnyi, A K Tikhaze, F T Ageev, V V Kukharchuk, Yu N Belenkov
We measured the content of lipid peroxides in plasma LDL from patients with chronic CHD not accompanied by hypercholesterolemia; CHD and hypercholesterolemia; type 2 diabetes mellitus and decompensation of carbohydrate metabolism; and CHD, circulatory insufficiency, and type 2 diabetes mellitus (without hypercholesterolemia). The content of lipid peroxides in LDL isolated from blood plasma by differential ultracentrifugation in a density gradient was estimated by a highly specific method with modifications (reagent Fe(2+) xylene orange and triphenylphosphine as a reducing agent for organic peroxides)...
July 2005: Bulletin of Experimental Biology and Medicine
S Raicevic, J V Wright, V Veljkovic, J L Conca
Addition of an amendment or reagent to soil/sediment is a technique that can decrease mobility and reduce bioavailability of uranium (U) and other heavy metals in the contaminated site. According to data from literature and results obtained in field studies, the general mineral class of apatites was selected as a most promising amendment for in situ immobilization/remediation of U. In this work we presented theoretical assessment of stability of U(VI) in four apatite systems (hydroxyapatite (HAP), North Carolina Apatite (NCA), Lisina Apatite (LA), and Apatite II) in order to determine an optimal apatite soil amendment which could be used for in situ remediation of uranium...
February 15, 2006: Science of the Total Environment
V Z Lankin, A K Tikhaze, G G Konovalova, M O Lisina, I B Nezhdanova, S B Gamboeva, V V Kukharchuk, Iu N Belenkov
AIM: To study an antioxidant action of antioxidant vitamins (vitamins C, E and provitamin A) in vitro and in vivo. MATERIAL AND METHODS: The study was made of kinetic parameters of copper-initiated free radical oxidation (FRO) of low density lipoproteins (HDLP) in human blood plasm, antioxidant potential of rat liver and myocardium, the level of FRO products in HDLP and activity of glutathione peroxidase in erythrocytes of 31 males aged 40-64 years with coronary heart disease (CHD)...
2004: Terapevticheskiĭ Arkhiv
V Z Lankin, V I Korchin, G G Konovalova, M O Lisina, A K Tikhaze, I G Akmaev
The severity of disturbances in carbohydrate metabolism in rats with alloxan-induced diabetes depended on activity of antioxidant enzymes in the target organ (pancreas). Damage to the pancreas is related to intensive generation of reactive oxygen species, free radicals, and lipid peroxides. Alloxan-induced diabetes in rats is a free radical disease, which in vivo serves as a useful model for the search for pharmacological preparations with antiradical and antioxidant properties. The antioxidant compound probucol indirectly increased activity of antioxidant enzymes in the pancreas and prevented the development of alloxan-induced diabetes in rats...
January 2004: Bulletin of Experimental Biology and Medicine
G G Konovalova, V Z Lankin, A K Tikhaze, I B Nezhdanova, M O Lisina, V V Kukharchuk
We studied the effect of a complex containing antioxidant vitamins C and E, provitamin A, and antioxidant element selenium on the contents of primary (lipid peroxides) and secondary products (malonic dialdehyde) of free radical lipid oxidation in low-density lipoproteins isolated from the plasma of patients with coronary heart disease and hypercholesterolemia by means of preparative ultracentrifugation. Activity of key antioxidant enzymes in the blood was measured during treatment with the antioxidant preparation...
August 2003: Bulletin of Experimental Biology and Medicine
L V Nedosugova, V Z Lankin, M I Balabolkin, G G Konovalova, M O Lisina, K V Antonova, A K Tikhaze, Yu N Belenkov
Glycosylation end-products formed during diabetes mellitus promoted atherogenic oxidative modification of low-density lipoproteins. We evaluated the effects of compensation of carbohydrate metabolism and therapy with antioxidant probucol on parameters of free radical oxidation in patients with type II diabetes mellitus. Compensation of carbohydrate metabolism reduced manifestations of oxidative stress, which was manifested in accelerated enzymatic utilization of reactive oxygen species and lipid peroxides and decreased content of free radical oxidation products in low-density lipoproteins...
August 2003: Bulletin of Experimental Biology and Medicine
No abstract text is available yet for this article.
1962: Zdravookhranenie Kazakhstana
No abstract text is available yet for this article.
May 1955: Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii
No abstract text is available yet for this article.
December 1964: Antibiotiki
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