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headache diagnosis review

Ferras Alwan, Chiara Vendramin, Ri Liesner, Amanda Clark, William Lester, Tina Dutt, William Thomas, Richard Gooding, Tina Biss, H G Watson, Nichola Cooper, Rachel Rayment, Tanya Cranfield, Joost J van Veen, Quentin A Hill, Sarah Davis, Jayashree Motwani, Neha Bhatnagar, Nicole Priddee, Marianna David, Maeve P Crowley, Jayanthi Alamelu, Hamish Lyall, John-Paul Westwood, Mari Thomas, Marie Scully
Congenital Thrombotic Thrombocytopenic Purpura (cTTP) is an ultra rare thrombomicroangiopathy caused by an inherited deficiency of ADAMTS13. There is limited data on the genotype-phenotype correlation and no consensus on treatment. We reviewed the largest cohort of cTTP cases, diagnosed in the UK, over the past 15 years. 73 cases of cTTP were diagnosed, confirmed by genetic analysis. 93% were alive at the time of review. 36% had homozygous mutations and 64% compound heterozygous mutations. Two presentation peaks were seen, childhood (median diagnosis age 3...
February 15, 2019: Blood
Abdulaziz AlMulhim, Ali AlMomen, Abdulrahman AlKhatib
INTRODUCTION: Intranasal teeth are a rare form of ectopic teeth. Their clinical manifestation are truly variable. In children, intranasal teeth are typically associated with cleft lip and alveolus. PRESENTATION OF CASE: Here, we report a case of 11 years -old girl presented with right nasal obstruction and occasional headache without any obvious etiology. 0Computed tomography of the paranasal sinuses (coronal and axial view) revealed displaced right upper maxillary tooth with the crown oriented inferiorly and medially toward and within the lower right anterior nasal cavity...
January 31, 2019: International Journal of Surgery Case Reports
John Alexander Brooks, Christopher McCudden, Ari Breiner, Pierre R Bourque
OBJECTIVE: We set out to test the discriminative power of an age-adjusted upper reference limit for cerebrospinal fluid total protein (CSF-TP) in identifying clinically relevant causes of albuminocytological dissociation (ACD). METHODS: We reviewed the charts of 2627 patients who underwent a lumbar puncture at a tertiary care centre over a 20-year period. Samples with CSF-TP above 45 mg/dL (0.45 g/L) were included. Samples with white cell count >5×109 /L, red cell count >50×109 /L and glucose <2...
February 13, 2019: BMJ Open
Lars Eichhorn, Marcus Thudium, Björn Jüttner
BACKGROUND: The symptoms of carbon monoxide (CO) poisoning are nonspecific, ranging from dizziness and headache to unconsciousness and death. A German national guideline on the diagnosis and treatment of this condition is lacking at present. METHODS: This review is based on a selective literature search in the PubMed and Cochrane databases, as well as on existing guidelines from abroad and expert recommendations on diagnosis and treatment. RESULTS: The initiation of 100% oxygen breathing as early as possible is the most important treatment for carbon monoxide poisoning...
December 24, 2018: Deutsches Ärzteblatt International
Pulak Parikh, Pasqualina Santaguida, Joy Macdermid, Anita Gross, Arshia Eshtiaghi
BACKGROUND: Neck pain (NP) is a very common musculoskeletal condition with potential for a high burden in disability and length of disorder. Clinical practice guidelines (CPG) give recommendations to clinicians for providing optimal care for patients however best practice recommendations are often contradictory. The purpose for this review was to conduct a SR of CPGs to assess the management recommendations for NP (diagnosis, treatment, prognosis, imaging). METHODS: Standard SR methodology was employed including a grey literature search (including the National Guideline Clearing House)...
February 14, 2019: BMC Musculoskeletal Disorders
Ke Wang, Xiu-Jian Ma, Shu-Yu Hao, Jiang Du, Li-Wei Zhang, Jun-Ting Zhang, Zhen Wu
OBJECTIVES: The diagnosis and management for juvenile psammomatoid ossifying fibroma of the skull base (JPOF) are challenging, and clinical data is limited. PATIENTS AND METHODS: A retrospective review of the JPOF was performed, and the clinical characteristics, treatment strategy and prognosis were analyzed. RESULTS: There were 23 patients pathologically confirmed with JPOF, most of which (19/23, 82.6%) were located at the skull base area; and 43...
February 8, 2019: World Neurosurgery
Mianwang He, Dan Gao, Jiatang Zhang, Dehui Huang, Yaping Tian, Shengyuan Yu
BACKGROUND: Suspected bacterial meningoencephalomyelitis as the presentation or trigger of neuromyelitis optica spectrum disorders (NMOSD) flare has not been reported in literature. CASE PRESENTATION: A 29 year old female, who has a history of neuromyelitis optica spectrum disorder (NMOSD) for 6 years, presented with symptoms of meningitits, encephalitis, myelitis, headache and fever. Cerebrospinal fluid analysis revealed pleocytosis (1131 × 106 /L [83% neutrophils]) and a glucose level of 39...
February 1, 2019: Multiple Sclerosis and related Disorders
Wen-Fang Chiang, Pei-Ti Chen, Yen-Lin Chen, Ming-Hua Chen
Posterior reversible encephalopathy syndrome (PRES) is a reversible vasogenic brain edema in patients who present with seizure, headache, visual disturbance, and altered mental status, and a characteristic neuroimaging profile. Although PRES predominantly affects the bilateral parieto-occipital areas, involvement of the frontal and temporal lobes, basal ganglia, brainstem, and cerebellum is not uncommon. Isolated involvement of the brainstem and cerebellum sparing the parieto-occipital lobe is rarely reported...
February 8, 2019: Hemodialysis International
Muhammad Noor, Alexander Leyva, John V Dennison, Barbara Manchec, Dhruv Patel
Esthesioneuroblastoma, also known as olfactory neuroblastoma, is a malignant tumor of the upper nasal cavity. This report illustrates the case of a 63-year-old woman who presented with intractable headaches. Subsequent radiologic evaluation and correlation with histopathologic analysis confirmed esthesioneuroblastoma. We review herein the typical computed tomographic (CT) and magnetic resonance (MR) imaging findings related to this locally destructive tumor, the prompt diagnosis of which may help prevent long-term morbidity and potentially, mortality...
November 28, 2018: Curēus
Alexander L Luryi, Elias M Michaelides, Seilesh Babu, Dennis I Bojrab, John F Kveton, Robert S Hong, John Zappia, Eric W Sargent, Christopher A Schutt
OBJECTIVES: To assess the accuracy of pre-operative diagnosis of masses of the cerebellopontine angle (CPA) when compared to surgical pathology. DESIGN: Retrospective chart review. PARTICIPANTS: Patients who underwent surgery for CPA masses at two tertiary care institutions from 2007 to 2017. MAIN OUTCOME MEASURES: Percent concordance between pre-operative and surgical pathologic diagnosis; sensitivity, specificity, positive predictive value, and negative predictive value for predicted diagnoses...
January 28, 2019: American Journal of Otolaryngology
R Kouitcheu, R Appay, M Diallo, L Troude, A Melot
Thymic epithelial tumors (TET) are rare lesions. The brain metastases of these tumors are even rarer. We report a case of brain metastases in a known patient with a thymic carcinoma diagnosed in October 2016. She was a 73-year-old woman who presented with headache, nausea, and right hemiplegia. Brain MRI revealed five lesions (1 insular, 1 frontal and 2 left temporal, 1 right parafalcine). These lesions were initially treated using two stereotactic radiosurgery gamma knives. A macroscopically complete excision of the left frontal lesion was subsequently performed without any complications with a good evolution of the neurological symptoms postoperatively...
January 30, 2019: Neuro-Chirurgie
Ivan D Carabenciov, Britta L Bureau, Michael Cutrer, Rodolfo Savica
The development of postconcussion syndrome after traumatic brain injury can result in a wide range of potentially debilitating symptoms that includes headaches, cognitive dysfunction, and mood disorders. Unfortunately, data on helpful medications are quite limited, particularly on the treatment of persistent headaches attributed to trauma. This retrospective medical record review used data collected from patients with a diagnosis of postconcussion syndrome in Mayo Clinic's Neurology and Physical Medicine and Rehabilitation outpatient clinics to evaluate the response of postconcussive symptoms to amantadine...
February 2019: Mayo Clinic Proceedings
Tommy Sheu, Tina M Briere, Adenike M Olanrewaju, Mary Frances McAleer
Purpose: Volumetric modulated arc therapy (VMAT) has been shown by multiple planning studies to hold dosimetric advantages over intensity modulated radiation therapy (IMRT) in the management of brain tumors, including glioblastoma (GBM). Although promising, the clinical impact of these findings has not been fully elucidated. Methods and Materials: We retrospectively reviewed consecutive patients with a pathologic-confirmed diagnosis of GBM who were treated between 2014 and 2015, a period that encompassed the transition from IMRT to VMAT at a single institution...
January 2019: Advances in Radiation Oncology
Rebecca Burch
Migraine and tension-type headache are highly prevalent. Migraine is associated with significant work- and family-related disability. Migraine is underdiagnosed; it reasonable to err on the side of migraine when choosing between primary headaches. Barriers to appropriate treatment of migraine include lack of access to providers, misdiagnosis, and acute and preventive therapies not being prescribed. Acute, rescue, and preventive treatment options are extensive, and new classes of treatments are either available or in development...
March 2019: Medical Clinics of North America
Hayley Barnes, Zoe Brown, Andrew Burns, Trevor Williams
BACKGROUND: Pulmonary hypertension (PH) comprises a group of complex and heterogenous conditions, characterised by elevated pulmonary artery pressure, and which left untreated leads to right-heart failure and death. PH includes World Health Organisation (WHO) Group 1 pulmonary arterial hypertension (PAH); Group 2 consists of PH due to left-heart disease (PH-LHD); Group 3 comprises PH as a result of lung diseases or hypoxia, or both; Group 4 includes PH due to chronic thromboembolic occlusion of pulmonary vasculature (CTEPH), and Group 5 consists of cases of PH due to unclear and/or multifactorial mechanisms including haematological, systemic, or metabolic disorders...
January 31, 2019: Cochrane Database of Systematic Reviews
Nicolas K Khattar, Andrew C White, Shawn W Adams, Zaid S Aljuboori, Michael J Wilder, Richard K Downs, Robert F James
Intracranial vascular pathologies often have overlapping clinical presentations. Dissected vessel occlusions and bifurcation aneurysms can appear similar on pretherapeutic imaging. The medical management of these two entities is drastically different. The patient is a 51-year-old man who presented with severe, sudden-onset headache. Initial presentation was consistent with a ruptured middle cerebral artery (MCA) aneurysm and surgical clipping was recommended. However, further review of radiographic findings could not definitively differentiate an aneurysmal origin of the symptoms as opposed to intracranial dissection followed by occlusion of the M2 branch of the MCA...
January 24, 2019: Journal of Neurointerventional Surgery
Ubong Ekpene, Mawuli Ametefe, Henry Akoto, Patrick Bankah, Teddy Totimeh, George Wepeba, Thomas Dakurah
Objective: This study seeks to describe the pattern of intracranial tumours in Korle Bu Teaching Hospital (KBTH) based on patient demographics, clinical presentation, spatial distribution of tumour and histological findings. Method: The study design is retrospective and descriptive. Data was obtained from the clinical records of patients with intracranial tumours treated in our neurosurgery unit between January 2010 to December 2015, and histology reports obtained from the histopathology unit...
June 2018: Ghana Medical Journal
Gennadiy A Katsevman, Ryan C Turner, Cletus Cheyuo, Charles L Rosen, Matthew S Smith
Posterior reversible encephalopathy syndrome (PRES) is an uncommon but potentially devastating syndrome if not recognized and treated appropriately. As the name implies, recognition of the condition and proper management may reverse the clinical and radiological findings. However, diagnosis is not always straightforward. We present the case of a 24-year-old female who was 4 days post-partum and presented with headache, neck pain, and new-onset seizures. She had undergone epidural anesthesia during labor, and initial imaging was suggestive of intracranial hypotension versus pachymeningitis...
January 18, 2019: Acta Neurochirurgica
M Gibaud, O Pauvert, S Gueden, J Durigneux, P Van Bogaert
Opsoclonus consists of massive erratic rapid eye jerks. They may occur in isolation or in association with myoclonus and ataxia, i.e., opsoclonus-myoclonus syndrome (OMS). We report the case of a 9-year-old girl who suffered from headaches for several days and was shown to have opsoclonus and left peripheral facial palsy. Work-up excluded the diagnosis of neuroblastoma, but CSF analysis showed aseptic meningitis, and serology for Borrelia burgdorferi (Lyme) was positive. The outcome was favorable with complete regression of symptoms after treatment with ceftriaxone 2g/day for 3 weeks...
January 14, 2019: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Anne-Laure Hermann, Marc Polivka, Marie-Pierre Loit, Jean-Pierre Guichard, Valérie Bousson
We present a case of 27-year-old female who presented for a progressive frontal swelling with ipsilateral headache. Subsequent CT scan revealed an extradural and expansile multiloculated mass with thin and strongly enhanced septations and MRI evaluation showed internal hyperintensity on T2 with no restriction of diffusion and confirmed the multiple cystic spaces with enhancing septations and rare hemorrhagic fluid-fluid levels. Surgery was performed and diagnosis of aneurysmal bone cyst was made on frozen section...
July 2018: Journal of Radiology Case Reports
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