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Hanan Adib-Tezer, Christiane Bayerl
No abstract text is available yet for this article.
October 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
(no author information available yet)
No abstract text is available yet for this article.
2016: Oncology Research and Treatment
Sophia M Wilden, Berenice M Lang, Peter Mohr, Stephan Grabbe
Seit Jahrzehnten ist bekannt, dass Tumoren vom Immunsystem erkannt und zerstört werden können. Diese, vor allem in Tierversuchen gewonnene Erkenntnis konnte jedoch in der Vergangenheit nicht zum Nutzen unserer Patienten umgesetzt werden, da immunonkologische Therapieansätze in den letzten Jahrzehnten in der Anwendung beim Menschen stets versagt haben. Daher hat, mit Ausnahme der adjuvanten Interferontherapie, keines dieser Verfahren den Einzug in die klinische Versorgung gefunden. Langzeitüberleben unter guter Lebensqualität war dabei sehr wenigen Patienten vorbehalten...
July 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Verónica Garza Rodríguez, Alberto De la Fuente García, Myrna Alejandra Cardoza Torres, Minerva Gómez Flores, Gildardo Jaramillo Moreno, Jorge Ocampo Candiani
Basal cell carcinomas (BCC) on the genital area account for less than 1% of all BCCs. Surgical management is indicated. Recurrence rate of vulvar BCC has been reported to be 10-20%. Mohs micrographic surgery (MMS) is a superior surgical option. Other treatments include radiation and topical immuntherapy. Cryosurgery for vulvar BCC has not been reported. We present the case of a 88-year-old Hispanic woman with a vulvar ulcer that was confirmed as BCC by histopathology and treated with liquid nitrogen cryosurgery...
April 2014: Indian Dermatology Online Journal
Péter Kovács, Gitta Pánczél, Kinga Borbola, Gabriella Juhász, Gabriella Liszkay
Immuntherapies are frequently accompanied by psychological side effects. Our goals were to detect the changes of psychological factors (depression, anxiety) among melanoma patients during ipilimumab treatment. Ten ipilimumab treated melanoma patients (Group 1.) and 18 low-dose interferon-alpha treated patients (Group 2.) were compared. In our longitudinal study we measured depression (Zung Self-Rating Depression Scale) and anxiety (State-Trait Anxiety Inventory, STAI). Psychological status was tested four times: in every 3 week during ipilimumab treatment according to the relevant treatment protocol and at baseline, 1st, 3rd and 6th month of interferon therapy...
October 2014: Pathology Oncology Research: POR
J Karkos
This review discusses the molecular basis and current status of immunotherapeutic strategies for prevention and treatment of Alzheimer's disease (AD). From the molecular view-point AD belongs to the group of conformational diseases. In-vitro studies demonstrated that monoclonal antibodies could modulate the conformation of Abeta peptides with subsequent inhibition of amyloid fibrils formation and aggregation. The efficacy of this approach was then successfully proved in the murine models of AD using predominantly Abeta (42) peptide as immunogen...
April 2004: Fortschritte der Neurologie-Psychiatrie
Patrice Binder, Olivier Attre, Jean Paul Boutin, Jean Didier Cavallo, Thierry Debord, Alain Jouan, Dominique Vidal
Biological weapons are considered as mass destruction and terror weapons. Terrorism including bioterrorism is the major threat in the future conflicts for our nations. The aim of bioterrorism is more related to the potential disorganisation of the society than to the lethal effects of the agents used. The dramatic consequences cannot be discarded, especially if contagious agents such viral are used. The preparation of specific defence measures is a major challenge for our countries. The knowledge acquired from the struggle against natural infectious diseases and recent events are essential to improve behaviours to face the biological weapon threats...
October 2003: Comparative Immunology, Microbiology and Infectious Diseases
K Halmy, J Serfozo, A Toth-Jakab
No abstract text is available yet for this article.
November 1981: Dermatologische Monatschrift
H W Waclawiczek, M Umlauft, R Weitgasser
The level of invasion of the primary tumor is a reliable criterion of prognosis for cutaneous melanoma. Hence it follows that a differential surgical treatment is possible especially in the clinical stage I. Primary treatment of malignant melanoma consists of three-dimensional excision. The width of excision is determinated by the microstage. The elective regional lymphadenectomy shows an apparant benefit for stage I melanoma with a level between 1.5 and 4.0 mm. The value of added treatments (radiotherapy, systemic, and local chemotherapy, immuntherapy) is still controversial, but should be considered in the future clinical and therapeutical research...
August 1984: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
L Hohenauer, G Eidenberger, F Eitelberger, G Tulzer
Among 829 consecutively treated neonatal intensive care patients during the years 1985 and 1986 46 cases of early onset type an 14 cases of late onset type (beyond the 4th day of life) of sepsis neonatorum were diagnosed. Mortality was 20%. In 40% of the cultures penicillin-resistant staphylococcus epidermidis was found. It was resistant to Penicillin however fully sensitive to Cefamandol, Netilmycine and Amicacine. Primary therapy of early onset type of sepsis has to be effective against Streptococci and against Listeria monocytogenes...
1988: Pädiatrie und Pädologie
L Samodai, L Kiss, Z Kolozsy, G Dauda, M Drinóczy, L Mohácsi
The authors reported their results of BCG immunotherapy in the treatment of the bladder cancer. between 1984-1989 60 superficial and 4 muscle infiltrative bladder tumors were treated. The results of 53 BCG treated superficial bladder cancer group were compared to control groups. The recurrence cases three-four times, the progressive cases eight-ten times were more in the control groups than it was found in the BCG group. They could not establish the value of BCG in the treatment of muscle infiltrative bladder cancer, because they had not appropriate number of patients and they could find only few articles in the literature...
August 5, 1990: Orvosi Hetilap
L Samodai, K Dankó
Alteration of natural killer (NK) activity from the peripherial blood was examined in the patients with superficial bladder cancer during two years between 1989-1991. The natural killer cell activity in patients with superficial bladder cancer was significantly depressed that activity was found in normal controls (P less than 0.01). 23 patients received intravesical BCG immuntherapy and NK activity was detected in the same patients 72 times in different period during the therapy. The authors decided that the activity of NK cells alters in BCG therapy...
September 6, 1992: Orvosi Hetilap
M V Pimm, R W Baldwin
C.parvum (Wellcome CN 6134) has been tested for tumour suppression against a range of syngeneically transplanted rat tumours, both carcinogen-induced and of spontaneous origin. Subcutaneous growth was not prevented by distant subcutaneous or intravenous injection of the preparation, although growth rates were sometimes depressed or accelerated. In contrast, C. parvum injected in admixture with tumour cells consistently suppressed their growth and with highly immunogenic tumours induced systemic tumour immunity, C...
December 15, 1977: International Journal of Cancer. Journal International du Cancer
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