keyword
https://read.qxmd.com/read/38536581/diagnostic-performance-of-ultrasound-in-the-assessment-of-gastric-contents-a-meta-analysis-and-systematic-review
#1
REVIEW
Xuanyuan Pan, Jun Chai, Xin Gao, Si Li, Jie Liu, Linxing Li, Yanjing Li, Zhichao Li
OBJECTIVE: To systematically analyze the accuracy of ultrasonic techniques in assessing the nature of gastric contents and their volume. METHODS: English-language articles that used ultrasonic techniques to assess the nature of gastric contents and their volume in patients were selected. In eligible studies, data were recalculated and analyzed for forest plots and subject summary curves of operating characteristics (SROC). Study quality was assessed using the diagnostic accuracy study quality assessment tool QUADAS-2...
March 27, 2024: Insights Into Imaging
https://read.qxmd.com/read/38535465/microencapsulation-of-lactobacillus-plantarum-with-improved-survivability-using-pufferfish-skin-gelatin-based-wall-materials
#2
JOURNAL ARTICLE
Honghui Guo, Yelin Zhou, Quanling Xie, Hui Chen, Yiping Zhang, Zhuan Hong, Sijin Chen, Ming'en Zhang
To improve the survivability of probiotics, Lactobacillus plantarum was microencapsulated using pufferfish skin gelatin (PSG)-based wall materials by spray-drying. This work investigated the protective effect of three different pH-dependent proteins (sodium caseinate (SC), soy protein isolate (SPI), and whey protein isolate (WPI)) combined with PSG on L. plantarum . The experimental results of spray-drying with an inlet temperature of 120 °C and an outlet temperature of 80 °C, storage at 4 °C for 6 months, simulated digestion, and turbidity indicated that PSG/SC had better stability and encapsulation effects and was more suitable to encapsulate L...
March 5, 2024: Marine Drugs
https://read.qxmd.com/read/38524419/the-effects-of-different-drying-methods-on-the-in-vitro-bioaccessibility-of-phenolics-antioxidant-capacity-and-morphology-of-european-plums-prunes-domestica-l
#3
JOURNAL ARTICLE
Elif Yener, Oznur Saroglu, Osman Sagdic, Ayse Karadag
Four different drying methods, hot-air-drying (HAD), vacuum-drying (VD), ultrasound-assisted vacuum-drying (US-VD), and freeze-drying (FD), were used to obtain dried plums ( Prunes domestica L .). These prunes were evaluated for their physical properties (such as color, rehydration ratio, and microstructural properties), phenolic compounds, and antioxidant activities before and after being subjected to in vitro digestion. TPC (total phenolic content) of plums ranged from 196.84 to 919.58 mg of GAE (gallic acid equivalent)/100 g of dw, and neochlorogenic acid was the most abundant phenolic compound...
March 19, 2024: ACS Omega
https://read.qxmd.com/read/38522704/in-vitro-digestive-properties-of-dictyophora-indusiata-polysaccharides-by-steam-explosion-pretreatment-methods
#4
JOURNAL ARTICLE
Zihao Zhang, Lin Wang, Baodong Zheng, Yi Zhang, Lei Pan
Dictyophora indusiata is medicinal and edible fungi containing various nutrients. The aim of this study was to investigate the efficient extraction and structural evolution of Dictyophora indusiata polysaccharides during the vitro digestion based on steam explosion pretreatment methods. In this study, the extraction rate of Dictyophora indusiata polysaccharides was optimized by steam explosion pretreatment methods, which was 2.46 folds that of the water extraction method. In addition, the digestion and fermentation properties of Dictyophora indusiata polysaccharides before and after steam explosion were evaluated in vitro by the changes of molecular weights, total and reducing sugars levels, surface morphology and functional groups, which showed that the structure of Dictyophora indusiata polysaccharides remained stable after salivary-gastric digestion, and partially entered the large intestine, where it could be utilized by gut microbiota...
March 22, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38519447/gastrointestinal-release-site-for-delayed-release-and-gelatin-capsules-in-healthy-dogs
#5
JOURNAL ARTICLE
Charles B Stone, Adam J Rudinsky, Rebecca J Urion, Simone B March, Jenessa A Winston
Gelatin capsules deliver their contents to the stomach, while delayed-release (DR) capsules are designed to allow delivery to the small intestine. This study evaluated the gastrointestinal release site of DR capsules in six healthy adult dogs compared to gelatin capsules. Both gelatin and DR capsules were filled with barium-impregnated polyethylene spheres (BIPS™), and following enteral administration, release site was assessed using abdominal radiographs at baseline, immediately after ingestion, 15 min post-ingestion, 30 min post-ingestion, and then every 30 min thereafter...
March 22, 2024: Journal of Veterinary Pharmacology and Therapeutics
https://read.qxmd.com/read/38513377/gut-microbiota-dependent-modulation-of-pre-metastatic-niches-by-jianpi-yangzheng-decoction-in-the-prevention-of-lung-metastasis-of-gastric-cancer
#6
JOURNAL ARTICLE
Xiaofei Zhu, Xingxing Zhang, Junyu Shen, Shanshan Zheng, Huaizhi Li, Bo Han, Cancan Zhang, Menglin Chen, Qingmin Sun, Jian Wu
AIM OF THE STUDY: To evaluate the in vitro and in vivo anti-metastasis efficacy of Jianpi Yangzheng (JPYZ) decoction against gastric cancer (GC) and its potential mechanisms. MATERIALS AND METHODS: The distant metastasis of GC cells administered via tail vein injection was assessed using the pre-metastatic niche (PMN) model. 16S rRNA sequencing and GC-MS/MS were applied to determine the component of the gut microbiota and content of short-chain fatty acids (SCFAs) in feces of mice, respectively...
February 4, 2024: Phytomedicine
https://read.qxmd.com/read/38503948/nek2-affects-the-ferroptosis-sensitivity-of-gastric-cancer-cells-by-regulating-the-expression-of-hmox1-through-keap1-nrf2
#7
JOURNAL ARTICLE
Jianyong Wu, Desheng Luo, Laizhen Tou, Hongtao Xu, Chuan Jiang, Dan Wu, Haifeng Que, Jingjing Zheng
NEK2 is a serine/threonine protein kinase that is involved in regulating the progression of various tumors. Our previous studies have found that NEK2 is highly expressed in gastric cancer and suggests that patients have a worse prognosis. However, its role and mechanism in gastric cancer are only poorly studied. In this study, we established a model of ferroptosis induced by RSL3 or Erastin in AGS cells in vitro, and konckdown NEK2, HOMX1, Nrf2 by siRNA. The assay kit was used to analyzed cell viability, MDA levels, GSH and GSSG content, and FeRhoNox™-1 fluorescent probe, BODIPY™ 581/591 C11 lipid oxidation probe, CM-H2DCFDA fluorescent probe were used to detected intracellular Fe2+ , lipid peroxidation, and ROS levels, respectively...
March 19, 2024: Molecular and Cellular Biochemistry
https://read.qxmd.com/read/38501821/fatty-acids-of-helicobacter-pylori-lipoproteins-cagt-and-lpp20
#8
JOURNAL ARTICLE
Mark S McClain, William E Boeglin, Holly M Scott Algood, Alan R Brash
Bacterial lipoproteins are post-translationally modified by the addition of acyl chains that anchor the protein to bacterial membranes. This modification includes two ester-linked and one amide-linked acyl chain on lipoproteins from Gram-negative bacteria. Helicobacter pylori lipoproteins have important functions in pathogenesis (including delivering the CagA oncoprotein to mammalian cells) and are recognized by host innate and adaptive immune systems. The number and variety of acyl chains on lipoproteins impact the innate immune response through Toll-like receptor 2...
March 19, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38501620/clinical-features-of-the-course-of-hirschspring-s-disease-inchildren-of-the-first-year
#9
JOURNAL ARTICLE
V Prytula, O Kurtash, V Rybalchenko
The purpose of the work - to investigate the peculiarities of the clinical course of Hirschsprung's disease in children of the first year of life and to determine the significance of symptoms in the verification of the disease. From 1980 to 2021, at the pediatric surgery clinic of the National Medical University named after O.O. Bogomolets on the basis of the National Children's Specialized Hospital "OKHMATDYT" and in the pediatric surgery clinic of the Ivano-Frankivsk National Medical University on the basis of the Ivano-Frankivsk Regional Children's Clinical Hospital, 483 children of the first year of life suffering from Hirschsprung's disease were examined and treated...
January 2024: Georgian Medical News
https://read.qxmd.com/read/38500153/the-effect-of-channa-striata-moringa-oleifera-and-curcuma-xanthorrhiza-extract-on-accelerating-recovery-in-a-ventilated-patient-with-hemorrhagic-shock-grade-3-due-to-prolonged-retained-placenta-a-case-report
#10
JOURNAL ARTICLE
Theresia Monica Rahardjo, Aloysius Suryawan, Nadya Rosa Amelia Rumouw, Hizkia Santoso, Amadea Jovita Miko Faustin
BACKGROUND: Most of critically ventilated patients with severe hemorrhagic shock experience metabolic acidosis, hypoalbuminemia, electrolyte imbalance, and increased production of free radical. Channa striata has a high content of albumin, an essential binding protein that contributes to homeostasis, and when combined with Moringa oleifera and Curcuma xanthorrhiza, they act as powerful antioxidants. Administration of C. striata, M. oleifera, and C. xanthorrhiza extract orally may benefit patient with hemodynamic issues, including significant blood loss...
March 19, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38499142/klf10-cbs-increases-the-sensitivity-of-gastric-carcinoma-cells-to-methionine-restriction-by-promoting-sulfur-transfer-pathway
#11
JOURNAL ARTICLE
Lin Xin, Zhi-Yang Liu, Chen-Xi Liu, Jie Sheng, Qi Zhou, Yi-Wu Yuan, Zhen-Qi Yue, Hao Lu, Jin-Heng Gan
Gastric cancer metastasis is a major cause of poor prognosis. Our previous research showed that methionine restriction (MR) lowers the invasiveness and motility of gastric carcinoma. In this study, we investigated the particular mechanisms of MR on gastric carcinoma metastasis. In vitro, gastric carcinoma cells (AGS, SNU-5, MKN7, KATO III, SNU-1, and MKN45) were grown in an MR medium for 24 h. In vivo, BALB/c mice were given a methionine-free (Met- ) diet. Transwell assays were used to investigate cell invasion and migration...
March 16, 2024: Experimental Cell Research
https://read.qxmd.com/read/38499083/intestinal-acyl-coa-synthetase-5-acsl5-deficiency-potentiates-postprandial-glp-1-pyy-secretion-reduces-food-intake-and-protects-against-diet-induced-obesity
#12
JOURNAL ARTICLE
John D Griffin, Ying Zhu, Andrew Reeves, Kimberly K Buhman, Andrew S Greenberg
OBJECTIVE: In the small intestine, the products of digestion of dietary triacylglycerol (TAG), fatty acids (FA) and monoacylglycerol, are taken up by absorptive cells, enterocytes, for systemic energy delivery. These digestion products can also bind receptors on endocrine cells to stimulate the release of hormones capable of influencing systemic energy metabolism. The initial phase of intestinal FA absorption involves the acylation of FAs to acyl-CoA by the acyl-CoA long chain synthetase (ACSL) enzymes...
March 16, 2024: Molecular Metabolism
https://read.qxmd.com/read/38498670/point-of-care-ultrasound-aids-in-the-management-of-patient-taking-semaglutide-before-surgery-a-case-report
#13
JOURNAL ARTICLE
John A Hodgson, Heine Rivera-Rodriguez, Peter Wu, Jaison Udani, Jeffrey Weiss
Semaglutide, a glucagon-like peptide-1 (GLP-1) analog, has various effects on the gastrointestinal tract. In patients undergoing anesthesia delayed gastric emptying time can have sequelae if not identified preoperatively. Modalities include thorough history regarding the last dose administration of a GLP-1 analog and ultrasound of gastric contents before induction of anesthesia. We present a case in which gastric ultrasound identified a patient at increased risk for aspiration on induction and allowed for appropriate alterations in the anesthetic plan...
March 1, 2024: A&A Practice
https://read.qxmd.com/read/38497625/effects-of-desmodium-caudatum-on-gastrointestinal-hormones-and-intestinal-flora-in-rats-with-gastritis
#14
JOURNAL ARTICLE
Lan Bu, Chengjia Tan, Bainian Zhang, Jian Hu, Xuemei Zhang, Xue Han, Hui Tian, Xiaoyan Ma
In order to preliminarily explore the effects of Desmodium caudatum on gastritis and intestinal flora in rats, a chronic gastritis rat model was established using the classic sodium salicylate method. Eighteen SPF rats were divided into three groups: the control group (Group C), the model group (Group M), and the treatment group (Group T). Pathological sections of the gastric wall were taken from rats in each group. Furthermore, the concentrations of gastrin and malondialdehyde in the serum of rats in each group were determined by ELISA...
March 1, 2024: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/38497432/george-sclavunos-1869-1954-anatomical-insights-and-his-contribution-into-the-magenstrasse-of-waldeyer
#15
JOURNAL ARTICLE
Ioanna Verzoviti, Michail Saintanis, Dimosthenis Chrysikos, Dimitrios Filippou, Dimitrios Schizas, Ioannis K Antonopoulos, Theodore Troupis
The purpose of this article is to present a well-known physician and highlight his contribution into an essential, but neglected anatomical feature. George Sclavunos (1869-1954) was a 20th century Greek physician, whose scientific work was a significant milestone in global medical knowledge. In 1899 he became Professor of Anatomy and Head Director of the Department of Anatomy. In 1906 Sclavunos G. published the first volume of the three volume book "Human Anatomy" (1906-1926), which is characterized by its unparalleled illustrations...
March 11, 2024: Acta Medica Academica
https://read.qxmd.com/read/38495103/the-effects-of-massa-medicata-fermentata-on-the-digestive-function-and-intestinal-flora-of-mice-with-functional-dyspepsia
#16
JOURNAL ARTICLE
Shuyu Wang, Yuanlin Li, Xiaoqi Yang, Yinxue Hao, Xueyan Zhan
Introduction: The purpose of this study was to identify the chemical components of Massa Medicata Fermentata (MMF) in different fermentation methods, analyze its regulatory effects on gastrointestinal propulsion and intestinal flora in mice with food accumulation, and further explore its mechanism of action in the treatment of dyspepsia. Methods: The chemical compositions of three kinds of MMF were identified using the UPLC-Q- Exactive Orbitrap mass spectrometer. A model of spleen deficiency and food accumulation in mice was established...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38494433/cholesterol-regulated-cellular-stiffness-may-enhance-evasion-of-nk-cell-mediated-cytotoxicity-in-gastric-cancer-stem-cells
#17
JOURNAL ARTICLE
Lijuan Zhu, Hongjing Wang
Gastric cancer has a high rate of recurrence, and as such, immunotherapy strategies are being investigated as a potential therapeutic strategy. Although the involvement of immune checkpoints in immunotherapy is well studied, biomechanical cues, such as target cell stiffness, have not yet been subject to the same level of investigation. Changes in the cholesterol content of the cell membrane directly influence tumor cell stiffness. Here, we investigated the effect of cholesterol on NK cell-mediated killing of gastric cancer stem-like cells...
March 17, 2024: FEBS Open Bio
https://read.qxmd.com/read/38494064/bile-acids-serve-as-endogenous-antagonists-of-the-leukemia-inhibitory-factor-lif-receptor-in-oncogenesis
#18
JOURNAL ARTICLE
Cristina Di Giorgio, Elva Morretta, Antonio Lupia, Rachele Bellini, Carmen Massa, Ginevra Urbani, Martina Bordoni, Silvia Marchianò, Ginevra Lachi, Pasquale Rapacciuolo, Claudia Finamore, Valentina Sepe, Maria Chiara Monti, Federica Moraca, Nicola Natalizi, Luigina Graziosi, Eleonora Distrutti, Michele Biagioli, Bruno Catalanotti, Annibale Donini, Angela Zampella, Stefano Fiorucci
The leukemia inhibitory factor (LIF) is member of interleukin (IL)-6 family of cytokines involved immune regulation, morphogenesis and oncogenesis. In cancer tissues, LIF binds a heterodimeric receptor (LIFR), formed by a LIFRβ subunit and glycoprotein(gp)130, promoting epithelial mesenchymal transition and cell growth. Bile acids are cholesterol metabolites generated at the interface of host metabolism and the intestinal microbiota. Here we demonstrated that bile acids serve as endogenous antagonist to LIFR in oncogenesis...
March 15, 2024: Biochemical Pharmacology
https://read.qxmd.com/read/38490380/sporisorium-reilianum-polysaccharides-improve-dss-induced-ulcerative-colitis-by-regulating-intestinal-barrier-function-and-metabolites
#19
JOURNAL ARTICLE
Shuaichen Liu, Lan Hong, Song Zhang, Yuxin Tian, Yuchen Wang, Duanduan Zhao, Jingheng Lv, Jingjing Zhuang, Hongyan Xu, Guangjun Xia
This study investigated the regulatory effects of Sporisorium reilianum polysaccharides (SRPS) on metabolism and the intestinal barrier in mice with colitis induced by dextran sulfate sodium (DSS). SRPS were resistant to the digestion of saliva, gastric juices, and intestinal fluid. SRPS significantly reduced the disease activity index and inhibited DSS-induced colon shortening. The expression of proinflammatory cytokines in the colon was normal (P < 0.05). Acetic acid, propionic acid, butyric acid, isobutyric acid, and isovaleric acid contents increased...
March 13, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38485835/association-of-glucagon-like-peptide-receptor-1-agonist-therapy-with-the-presence-of-gastric-contents-in-fasting-patients-undergoing-endoscopy-under-anesthesia-care-a-historical-cohort-study
#20
JOURNAL ARTICLE
Fei Wu, Matthew R Smith, Ariel L Mueller, Seth A Klapman, Lucinda L Everett, Timothy Houle, Braden Kuo, Ion A Hobai
PURPOSE: We aimed to estimate the association of glucagon-like peptide 1 (GLP-1) receptor agonist therapy with the incidence of endoscopically visible gastric contents after preprocedural fasting. METHODS: We reviewed the records of esophagogastroduodenoscopy (EGD) performed at our institution between 2019 and 2023 and determined the presence of residual gastric contents from the procedure notes and saved images. We compared patients taking GLP-1 agonists at the time of the procedure (GLP group, 90 procedures) with patients who started GLP-1 agonist therapy within 1,000 days after undergoing EGD (control, 102 procedures)...
March 14, 2024: Canadian Journal of Anaesthesia
keyword
keyword
161297
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.