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Atrial fibrilation anemia

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https://read.qxmd.com/read/30865367/clinical-features-of-heart-failure-with-mid-range-and-preserved-ejection-fraction-in-octogenarians-results-of-a-multicenter-observational-study
#1
Bülent Özlek, Eda Özlek, Mehmet Tekinalp, Serkan Kahraman, Hicaz Zencirkıran Ağuş, Oğuzhan Çelik, Cem Çil, Bedri Caner Kaya, İbrahim Rencüzoğulları, Kadir Uğur Mert, Mustafa Ozan Çakır, Altuğ Ösken, Lütfü Bekar, Yunus Çelik, Özcan Başaran, Volkan Doğan, Gurbet Özge Mert, Kadriye Memiç Sancar, Samet Sevinç, Murat Biteker
OBJECTIVES: To compare real-world characteristics and management of individuals aged 80 and older with heart failure (HF) and mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) derived from a large cohort of survey and to compare them with those younger than 80 from the same survey. METHODS: This is an observational, multicenter and cross-sectional study conducted in Turkey (NCT03026114). Consecutive 1,065 (mean age of 67...
March 13, 2019: International Journal of Clinical Practice
https://read.qxmd.com/read/30803938/derivation-and-external-validation-of-a-simple-risk-tool-to-predict-30-day-hospital-readmissions-after-transcatheter-aortic-valve-replacement
#2
Sahil Khera, Dhaval Kolte, Salil Deo, Ankur Kalra, Tanush Gupta, Dawn Abbott, Neal Kleiman, Deepak L Bhatt, Gregg C Fonarow, Omar K Khalique, Susheel Kodali, Martin B Leon, Sammy Elmariah
AIMS: Patients undergoing transcatheter aortic valve replacement (TAVR) possess a higher risk of recurrent healthcare resource utilization due to multiple comorbidities, frailty, and advanced age. We sought to devise a simple tool to identify TAVR patients at increased risk of 30-day readmission. METHODS AND RESULTS: We used the Nationwide Readmissions Databases from January 2013 to September 2015. Complex survey methods and hierarchical regression in R were implemented to create a prediction tool to determine probability of 30-day readmission...
February 26, 2019: EuroIntervention
https://read.qxmd.com/read/30797248/extended-hospital-stay-after-radical-cystectomy-with-enhanced-recovery-protocol
#3
Hatim Thaker, Saum Ghodoussipour, Mateen Saffarian, Akbar Ashrafi, Gus Miranda, Jie Cai, Anne K Schuckman, Monish Aron, Mihir Desai, Inderbir S Gill, Siamak Daneshmand, Hooman Djaladat
INTRODUCTION: To evaluate the reasons leading to an extended hospital stay (EHS) in patients undergoing radical cystectomy (RC) with postoperative enhanced recovery after surgery (ERAS) protocol. MATERIALS AND METHODS: A total of 509 patients underwent RC and urinary diversion with ERAS between May 2012 and March 2017. The protocol includes no bowel preparation, early feeding, predominantly non-narcotic pain control and µ opioid antagonists. Non-consenting/lost to follow up patients, and those with non-urothelial carcinoma were excluded...
February 2019: Canadian Journal of Urology
https://read.qxmd.com/read/30692466/-recurrent-gastric-cancer-with-tumor-bleeding-from-a-metastatic-lymph-node-invading-the-duodenal-stump-successfully-controlled-by-palliative-radiotherapy-a-case-report
#4
Takuya Hamakawa, Kazuhiro Nishikawa, Motohiro Hirao, Eiichi Tanaka, Tetsuya Iwasaki, Ryo Shimoyama, Sakae Maeda, Ayako Fujiwara, Mamoru Uemura, Masakazu Miyake, Naoki Hama, Atsushi Miyamoto, Takeshi Kato, Koji Takami, Mitsugu Sekimoto
An 82-year-old man receiving oral administration of warfarin for atrial fibrillation underwent distal gastrectomy for advanced gastric cancer. The postoperative diagnosis was pT3(SS)N2M1H1P0CY0, pStage Ⅳ,(HER2, score 3+)gastric cancer. He received chemotherapy for the treatment of multiple liver metastases, following which, he developed lymph node metastases. Grade 3 anemia was observed at 46 months after initiation of chemotherapy when he was treated with third-line irinotecan plus cisplatin. Abdominal CT showed that CR for liver metastases and SD for lymph node metastases were maintained...
December 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/30658917/predictors-of-hospital-cost-after-transcatheter-aortic-valve-implantation-in-the-united-states-from-the-nationwide-inpatient-sample-database
#5
Tomo Ando, Oluwole Adegbala, Pedro A Villablanca, Emmanuel Akintoye, Said Ashraf, Alexandros Briasoulis, Tesfaye Telila, Hisato Takagi, Cindy L Grines, Theodore Schreiber, Deepak L Bhatt, Luis Afonso
We aimed to identify risk factors of high hospitalization cost after transcatheter aortic valve implantation (TAVI). TAVI expenditure is generally higher compared with surgical aortic valve replacement. We queried the Nationwide Inpatient Sample database from January 2011 to September 2015 to identify those who underwent endovascular TAVI. Estimated cost of hospitalization was calculated by merging the Nationwide Inpatient Sample database with cost-to-charge ratios available from the Healthcare Cost and Utilization Project...
January 8, 2019: American Journal of Cardiology
https://read.qxmd.com/read/30627277/gastrointestinal-bleeding-in-patients-with-acute-respiratory-distress-syndrome-a-national-database-analysis
#6
Faraz Siddiqui, Moiz Ahmed, Saqib Abbasi, Akshay Avula, Abdul Hasan Siddiqui, Jobin Philipose, Hafiz M Khan, Tahir M A Khan, Liliane Deeb, Michel Chalhoub
Background: The goal of our study was to determine the impact of gastrointestinal bleeding (GIB) on in-hospital outcomes among acute respiratory distress syndrome (ARDS) patients, and subsequently determine the potential risk factors for the development of GIB. Methods: ARDS patients with and without GIB were identified using the National Inpatient Sample (2002 - 2012). Linear regression analysis was used to assess impact of GIB on in-hospital mortality, length of stay and total charges...
January 2019: Journal of Clinical Medicine Research
https://read.qxmd.com/read/30591323/different-determinants-of-vascular-and-nonvascular-deaths-in-patients-with-atrial-fibrillation-a-sakura-af-registry-substudy
#7
Keiichiro Kuronuma, Yasuo Okumura, Katsuaki Yokoyama, Naoya Matsumoto, Eizo Tachibana, Koji Oiwa, Michiaki Matsumoto, Toshiaki Kojima, Shoji Hanada, Kazumiki Nomoto, Ken Arima, Fumiyuki Takahashi, Tomobumi Kotani, Yukitoshi Ikeya, Seiji Fukushima, Satoru Itou, Kunio Kondo, Masaaki Chiku, Yasumi Ohno, Motoyuki Onikura, Atsushi Hirayama
BACKGROUND: The incidence and causes of death among patients in Japan treated for atrial fibrillation (AF), a major determinant of strokes and death, with direct oral anticoagulants (DOACs) are unclear. This study's aim was two-fold: to compare the incidence and causes of death between DOAC and warfarin users in Japan and to identify the factors associated with vascular and nonvascular death in the Japanese AF population. METHODS: The study was based on the SAKURA AF registry, in which clinical events were tracked in 3267 enrollees from 63 institutions for 2-4 years...
March 2019: Journal of Cardiology
https://read.qxmd.com/read/30554250/triple-therapy-at-discharge-from-internal-medicine-wards-in-heart-failure-patients-with-reduced-ejection-fraction-results-from-an-observational-study
#8
A Fortini, V Verdiani, G Panigada, C Angotti, L Masotti
BACKGROUND: Guidelines recommend triple therapy (TT) with ACE inhibitors or ARBs, beta-blockers and mineralcorticoid receptor antagonists in symptomatic heart failure patients with ejection fraction <35 % (HFrEF). Nevertheless, many patients remain untreated. This study was aimed to evaluate the use of TT in HFrEF patients discharged from internal medicine wards of Tuscany, Italy. METHODS AND RESULTS: We analyzed the database of a multicenter observational study which included 770 patients consecutively hospitalized for HF in 32out of 36 Internal Medicine Units of Tuscany, Italy...
November 2018: La Clinica Terapeutica
https://read.qxmd.com/read/30371187/thirty-day-readmission-rates-timing-causes-and-costs-after-st-segment-elevation-myocardial-infarction-in-the-united-states-a-national-readmission-database-analysis-2010-2014
#9
Luke K Kim, Ilhwan Yeo, Jim W Cheung, Rajesh V Swaminathan, S Chiu Wong, Konstantinos Charitakis, Oluwayemisi Adejumo, John Chae, Robert M Minutello, Geoffrey Bergman, Harsimran Singh, Dmitriy N Feldman
Background Readmission after ST-segment-elevation myocardial infarction ( STEMI ) poses an enormous economic burden to the US healthcare system. Efforts to prevent readmissions should be based on understanding the timing and causes of these readmissions. This study aimed to investigate contemporary causes, timing, and cost of 30-day readmissions after STEMI . Methods and Results All STEMI hospitalizations were selected in the Nationwide Readmissions Database ( NRD ) from 2010 to 2014. The 30-day readmission rate as well as the primary cause and cost of readmission were examined...
September 18, 2018: Journal of the American Heart Association
https://read.qxmd.com/read/30371179/causes-and-predictors-of-30-day-readmission-in-patients-with-syncope-collapse-a-nationwide-cohort-study
#10
Amer N Kadri, Hasan Abuamsha, Leen Nusairat, Nazih Kadri, Hussam Abuissa, Ahmad Masri, Adrian V Hernandez
Background Syncope accounts for 0.6% to 1.5% of hospitalizations in the United States. We sought to determine the causes and predictors of 30-day readmission in patients with syncope. Methods and Results We identified 323 250 encounters with a primary diagnosis of syncope/collapse in the 2013-2014 Nationwide Readmissions Database. We excluded patients younger than 18 years, those discharged in December, those who died during hospitalization, hospital transfers, and those whose length of stay was missing. We used multivariable logistic regression analysis to evaluate the association between baseline characteristics and 30-day readmission...
September 18, 2018: Journal of the American Heart Association
https://read.qxmd.com/read/30360892/incidence-predictors-and-in-hospital-outcomes-of-transcatheter-aortic-valve-implantation-after-nonelective-admission-in-comparison-with-elective-admission-from-the-nationwide-inpatient-sample-database
#11
Tomo Ando, Oluwole Adegbala, Pedro Villablanca, Emmanuel Akintoye, Said Ashraf, Mohamed Shokr, Alexandros Briasoulis, Hisato Takagi, Cindy L Grines, Luis Afonso, Theodore Schreiber
Candidates for transcatheter aortic valve implantation (TAVI) are generally older with multiple co-morbidities and are therefore susceptible to nonelective admissions before scheduled TAVI. Frequency, predictors, and outcomes of TAVI after nonelective admission are under-explored. We queried the Nationwide Inpatient Sample database, an administrative database, from January 2012 to September 2015 to identify hospitalization in those age ≥50 who had transarterial TAVI. A propensity-matched cohort was created to compare the outcomes between nonelective and elective admission who had TAVI...
September 26, 2018: American Journal of Cardiology
https://read.qxmd.com/read/30277905/comparative-clinical-outcomes-of-edoxaban-in-adults-with-nonvalvular-atrial-fibrillation
#12
Wilbert S Aronow, Tatyana A Shamliyan
BACKGROUND: A critical appraisal of all pooled evidence regarding novel oral anticoagulants (NOACs) for stroke prevention regardless of publication status or study design has not been conducted yet. Being the latest addition to NOACs, the data on edoxaban are especially scarce. STUDY QUESTION: What are the comparative clinical outcomes of edoxaban versus warfarin and other NOACs apixaban, dabigatran, or rivaroxaban in adults with nonvalvular atrial fibrillation? DATA SOURCES: Randomized controlled trials (RCTs), observational studies, and network meta-analyses were identified in PubMed, EMBASE, the Cochrane Library, Pharmapendium, Elsevier Clinical Pharmacology, and the clinicaltrials...
September 18, 2018: American Journal of Therapeutics
https://read.qxmd.com/read/30276661/red-cell-distribution-width-predicts-mid-term-prognosis-in-patients-hospitalized-with-acute-heart-failure-the-rdw-in-acute-heart-failure-re-ahf-study
#13
Remo Melchio, Gianluca Rinaldi, Elisa Testa, Alessia Giraudo, Cristina Serraino, Christian Bracco, Laura Spadafora, Andrea Falcetta, Stefano Leccardi, Alberto Silvestri, Luigi Fenoglio
The aim of the study was to evaluate the prognostic role of red cell distribution width (RDW) in a broad population of patients hospitalized for acute heart failure (AHF). In a retrospective cohort observational study, 451 consecutive patients discharged for AHF were categorized in patients with low RDW (≤ 14.8%) and high RDW (> 14.8%). The rates of death from all causes or of hospital readmission for worsening heart failure and death were determined after a median follow-up of 18 months. The overall population has a median age of 80 years (IQR 72-85), 235 patients (52%) were males...
October 1, 2018: Internal and Emergency Medicine
https://read.qxmd.com/read/30251901/life-threatening-drug-induced-liver-injury-in-a-patient-with-%C3%AE-thalassemia-major-and-severe-iron-overload-on-polypharmacy
#14
Maddalena Casale, Stefania Picariello, Felice Corvino, Giuseppe Cerasari, Saverio Scianguetta, Francesca Rossi, Marcello Persico, Silverio Perrotta
A 20-year-old male affected by transfusion-dependent β-thalassemia (β-thal), was prescribed intensive chelation therapy with deferoxamine (DFO) and deferiprone (DFP) because of severe hepatic and cardiac iron overload and β-blocker and warfarin to manage a previous event of atrial fibrillation (AFib) and heart failure. After a few months, he developed critical liver failure, renal tubulopathy and severe electrolyte imbalance. Laboratory and instrumental evaluations were performed to carry out differential diagnosis of acute liver failure and an exclusion diagnosis of drug induced liver injury (DILI) was made...
September 25, 2018: Hemoglobin
https://read.qxmd.com/read/30219202/registry-of-left-atrial-appendage-closure-and-initial-experience-with-intracardiac-echocardiography
#15
Liliana Reis, Luís Paiva, Marco Costa, Joana Silva, Rogério Teixeira, Ana Botelho, Paulo Dinis, Marta Madeira, Joana Ribeiro, José Nascimento, Lino Gonçalves
INTRODUCTION: Percutaneous closure of the left atrial appendage (LAA) is a promising therapy in patients with atrial fibrillation with high risk for stroke and contraindication for oral anticoagulation (OAC). Intracardiac echocardiography (ICE) may make this percutaneous procedure feasible in patients in whom transesophageal echocardiography (TEE) is inadvisable. Our aim was to assess the efficacy and safety of LAA closure and the feasibility of ICE compared to TEE to guide the procedure...
September 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://read.qxmd.com/read/30212481/red-cell-distribution-width-and-common-disease-onsets-in-240-477-healthy-volunteers-followed-for-up-to-9-years
#16
Luke C Pilling, Janice L Atkins, George A Kuchel, Luigi Ferrucci, David Melzer
Higher Red Blood Cell Distribution Width (RDW or anisocytosis) predicts incident coronary artery disease (CAD) plus all-cause and cardiovascular mortality, but its predictive value for other common diseases in healthy volunteers is less clear. We aimed to determine the shorter and longer term associations between RDW and incident common conditions in participants free of baseline disease, followed for 9 years. We undertook a prospective analysis of RDW% using 240,477 healthy UK Biobank study volunteers aged 40-70 years at baseline, with outcomes ascertained during follow-up (≤9 years)...
2018: PloS One
https://read.qxmd.com/read/30168227/developing-a-risk-score-to-predict-mortality-in-the-first-year-after-implantable-cardioverter-defibrillator-implantation-data-from-the-israeli-icd-registry
#17
Roman Nevzorov, Ilan Goldenberg, Yuval Konstantino, Gregory Golovchiner, Boris Strasberg, Mahmoud Souleiman, Vladimir Khalameizer, Shlomit Ben-Zvi, Ron Sela, Shimon Rosenheck, Nahum A Freedberg, Michael Geist, Michal Einhorn Cohen, Tal Cohen, Nir Shlomo, Natalie Gabrielov-Yusim, Diklah Geva, Michael Glikson, Moti Haim
INTRODUCTION: Life expectancy of less than 1 year is usually a contraindication for implantable cardioverter defibrillator (ICD) implantation. The aim was to identify patients at risk of death during the first year after implantation. METHODS AND RESULTS: Data were derived from a prospective Israeli ICD Registry. Two groups of patients were compared, those who died and those who were alive 1 year after ICD implantation. Factors associated with 1-year mortality were identified on a derivation cohort...
August 31, 2018: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/30140582/traumatic-and-spontaneous-intracranial-hemorrhage-in-atrial-fibrillation-patients-on-warfarin
#18
Heidi Lehtola, Antti Palomäki, Pirjo Mustonen, Päivi Hartikainen, Tuomas Kiviniemi, Henri Sallinen, Ilpo Nuotio, Antti Ylitalo, K E Juhani Airaksinen, Juha Hartikainen
Background: Intracranial hemorrhage is the most devastating complication in patients with atrial fibrillation (AF) receiving oral anticoagulation (OAC). It can be either spontaneous or caused by head trauma. We sought to address the prevalence, clinical characteristics, and prognosis of traumatic and spontaneous intracranial hemorrhages in AF patients on OAC. Methods: Multicenter FibStroke registry of 5,629 patients identified 592 intracranial hemorrhages during warfarin treatment between 2003 and 2012...
August 2018: Neurology. Clinical Practice
https://read.qxmd.com/read/30064926/hospital-readmission-following-transcatheter-aortic-valve-implantation-in-the-real-world
#19
Takahide Arai, Fumiaki Yashima, Ryo Yanagisawa, Makoto Tanaka, Hideyuki Shimizu, Keiichi Fukuda, Yusuke Watanabe, Toru Naganuma, Motoharu Araki, Norio Tada, Futoshi Yamanaka, Shinichi Shirai, Masanori Yamamoto, Kentaro Hayashida
BACKGROUND: There is limited data on hospital readmissions following transcatheter aortic valve implantation (TAVI). The aim of this study was to investigate hospital readmissions post-TAVI. METHODS: Data from the Optimized transCathEter vAlvular iNtervention (OCEAN-TAVI) multicenter registry (registration no. UMIN000020423) were collected from 1215 patients who underwent TAVI. Incidence, timing, causes, and predictors of readmission in addition to the impact on patient outcomes were analyzed...
October 15, 2018: International Journal of Cardiology
https://read.qxmd.com/read/30058431/major-bleeding-with-apixaban-in-atrial-fibrillation-patient-characteristics-management-and-outcomes
#20
Sarah Eisho, Nouran M Salem, Janet L Hoffman, John M Koerber, Maureen A Smythe
OBJECTIVES: To identify patient characteristics, bleed management, and bleed outcomes in patients experiencing an apixaban major bleeding event and to identify opportunities to improve the safe use of apixaban. METHODS: This retrospective single health-system study identified apixaban patients experiencing a major bleeding event between January 2013 and May 2016 through electronic medical record review. Patient characteristics, bleed management, and outcomes were extracted in those with a confirmed major bleed assessed by the International Society on Thrombosis and Haemostasis criteria...
October 2018: Hospital Practice (Minneapolis)
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