N Zayed, H Munjaković, M K Aktan, K Simoens, K Bernaerts, N Boon, A Braem, F Pamuk, M Saghi, W Van Holm, A Fidler, R Gašperšič, W Teughels
Preventing the development and recurrence of periodontal diseases often includes antimicrobial mouthrinses to control the growth of the periodontal pathogens. Most antimicrobials are nonselective, targeting the symbiotic oral species as well as the dysbiosis-inducing ones. This affects the overall microbial composition and metabolic activity and consequently the host-microbe interactions, which can be detrimental (associated with inflammation) or beneficial (health-associated). Consequently, guiding the antimicrobial effect for modulating the microbial composition to a health-associated one should be considered...
January 7, 2024: Journal of Dental Research