keyword
https://read.qxmd.com/read/38640876/glioblastoma-mechanobiology-at-multiple-length-scales
#21
JOURNAL ARTICLE
Raghu Vamsi Kondapaneni, Sumiran Kumar Gurung, Pinaki S Nakod, Kasra Goodarzi, Venu Yakati, Nicholas A Lenart, Shreyas S Rao
Glioblastoma multiforme (GBM), a primary brain cancer, is one of the most aggressive forms of human cancer, with a very low patient survival rate. A characteristic feature of GBM is the diffuse infiltration of tumor cells into the surrounding brain extracellular matrix (ECM) that provide biophysical, topographical, and biochemical cues. In particular, ECM stiffness and composition is known to play a key role in controlling various GBM cell behaviors including proliferation, migration, invasion, as well as the stem-like state and response to chemotherapies...
April 15, 2024: Biomater Adv
https://read.qxmd.com/read/38640724/social-support-and-the-burden-of-physical-and-psychiatric-comorbidities-in-the-patients-with-late-onset-epilepsy-in-china-a-cross-sectional-study
#22
JOURNAL ARTICLE
Shengyi Liu, Zhen Cao, Zihua He, Wenyan Shi, Jinmei Li
INTRODUCTION: Epilepsy is the third most common neurological disorder in elderly people. Patients with epilepsy (PWEs) are more likely to have comorbidities. Social support is very important for PWEs. However, there are many gaps in the research on social support in older PWEs, especially the correlation between social support and comorbidities. METHODS: A cross-sectional study was conducted in three hospitals in China. Social support was assessed using the Social Support Rate Scale...
April 18, 2024: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38640582/emotion-recognition-in-amyotrophic-lateral-sclerosis-in-a-dynamic-environment
#23
JOURNAL ARTICLE
Marco Ceccanti, Laura Libonati, Federica Moret, Edoardo D'Andrea, Maria Cristina Gori, Francesco Saverio Bersani, Maurizio Inghilleri, Chiara Cambieri
OBJECTIVE: The aim of our study was to measure the ability of ALS patients to process dynamic facial expressions as compared to a control group of healthy subjects and to correlate this ability in ALS patients with neuropsychological, clinical and neurological measures of the disease. METHODS: Sixty-three ALS patients and 47 healthy controls were recruited. All the ALS patients also underwent i) the Geneva Emotion Recognition Test (GERT) in which ten actors express 14 types of dynamic emotions in brief video clips with audio, ii) the Edimburgh Cognitive and Behavioral ALS Screen (ECAS) test; iii) the ALS Functional Rating Scale Revised (ALSFRS-R) and iv) the Medical Research Council (MRC) for the evaluation of muscle strength...
April 16, 2024: Journal of the Neurological Sciences
https://read.qxmd.com/read/38640400/the-effects-of-yoga-breathing-before-motor-speech-practice-in-acquired-apraxia-of-speech-an-n-of-1-trial
#24
JOURNAL ARTICLE
Erica Freestone, Jacqueline Laures Gore, Rebecca Shisler Marshall, Elliot Moore, Eva van Leer
A previous study discovered that two speakers with moderate apraxia of speech increased their sequential motion rates after unilateral forced-nostril breathing (UFNB) practiced as an adjunct to speech-language therapy in an AB repeated-measures design. The current study sought to: (1) delineate possible UFNB plus practice effects from practice effects alone in motor speech skills; (2) examine the relationships between UFNB integrity, participant-reported stress levels, and motor speech performance; and (3) sample a participant-led UFNB training schedule to contribute to the literature's growing understanding of UFNB dosage...
April 1, 2024: International Journal of Yoga Therapy
https://read.qxmd.com/read/38639666/-application-of-imchb-based-nursing-model-in-self-efficacy-and-negative-emotion-of-prostate-cancer-radiotherapy-patients
#25
JOURNAL ARTICLE
Qing Zhang, Qian Lan, Zhen-Zhu Cao, Juan Li, Xin Zhao, Ao-Mei Li
OBJECTIVE: To study the impact of the nursing model based on the interactive model of health behavior (IMCHB) on the self-efficacy and negative emotions of prostate cancer patients. METHODS: 70 cases clinically admitted to our hospital from January 1, 2021 to January 31, 2023 Patients who received radiotherapy for prostate cancer were taken as research subjects and divided into a control group (n=35) and an observation group (n=35) according to the random drawing method...
October 2023: Zhonghua Nan Ke Xue, National Journal of Andrology
https://read.qxmd.com/read/38638962/effects-of-physical-exercise-on-adolescent-short-video-addiction-a-moderated-mediation-model
#26
JOURNAL ARTICLE
He Jianfeng, Zhuo Xian, Ai Zexiu
OBJECTIVE: To discuss the effects of physical exercise (PE) on adolescent short video addiction (SVA) and analyze the mediating effects of self-control (SC) and the moderating effects of the cumulative ecological risk (CER), aiming to provide theoretical support for PE relative to adolescent SVA, investigate the underlying mechanisms of the effects of PE. METHODS: The Physical Activity Rating Scale-3, Problematic TikTok Use Scale, Self-Control Scale, and Cumulative Ecological Risk Scale were used to survey 756 adolescents in Chongqing and Chengdu, China...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38638942/exploring-cold-plasma-technology-enhancements-in-carob-seed-germination-phytochemical-composition-and-antioxidant-activity
#27
JOURNAL ARTICLE
Khadija Ben Othman, Mohamed Majdi Cherif, Imen Assadi, Walid Elfalleh, Lotfi Khezami, Achraf Ghorbal, Aymen Amine Assadi
The cultivation of carob tree does not need many climatic and ecological requirements. The main limit to its large-scale cultivation is the defects for propagation with seeds. Addressing this, our study evaluated the effect of cold plasma pretreatment on carob seed germination. Impressively, cold plasma showcased beneficial effects by significantly increasing water uptake in seeds (CS: 1.71 ± 0.59; PS/3.99 ± 1.56) and decreasing the contact angle from 80.7° to 57.9°, enhancing the seed surface's hydrophilicity...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38638608/acceptability-and-feasibility-of-policy-implementation-strategies-for-taxes-earmarked-for-behavioral-health-services
#28
JOURNAL ARTICLE
Jonathan Purtle, Nicole A Stadnick, Megan Wynecoop, Sarah C Walker, Eric J Bruns, Gregory A Aarons
BACKGROUND: This study's aims are to: (1) Compare the acceptability and feasibility of five types of implementation strategies that could be deployed to increase the reach of evidence-based practices (EBPs) with revenue from policies that earmark taxes for behavioral health services, and (2) Illustrate how definitions of implementation strategies and measures of acceptability and feasibility can be used in policy-focused implementation science research. METHODS: Web-based surveys of public agency and community organization professionals involved with earmarked tax policy implementation were completed in 2022-2023 ( N  = 211, response rate = 24...
2024: Front Health Serv
https://read.qxmd.com/read/38638511/coping-as-a-resource-to-allow-for-psychosocial-adjustment-in-fatal-disease-results-from-patients-with-amyotrophic-lateral-sclerosis
#29
JOURNAL ARTICLE
Julia Finsel, Angela Rosenbohm, Raphael S Peter, Hansjörg Bäzner, Axel Börtlein, Silke Dempewolf, Martin Schabet, Martin Hecht, Andreas Kohler, Christian Opherk, Andrea Nägele, Norbert Sommer, Alfred Lindner, Dietrich Rothenbacher, Albert C Ludolph, Gabriele Nagel, Dorothée E Lulé
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal disorder, which imposes a severe emotional burden on patients. Appropriate coping mechanisms may alleviate this burden and facilitate wellbeing, with social support known to be a successful coping strategy. This observational study aimed to determine the interplay of general coping traits of hope for success and fear of failure, coping behavior of social activity, and patients' wellbeing. METHODS: In this cross-sectional study, patients with ALS from a clinical-epidemiological registry in Southwestern Germany were interviewed regarding coping traits (achievement-motivated behavior: hope for success and fear of failure), coping behavior of social activity, and psychosocial adjustment, determined using measures of depressiveness, anxiety [both measured by Hospital Anxiety and Depression Scale (HADS)], and quality of life [Anamnestic Comparative Self-Assessment (ACSA)]...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38637442/development-and-validation-of-the-emotional-climate-change-stories-eccs-stimuli-set
#30
JOURNAL ARTICLE
Dominika Zaremba, Jarosław M Michałowski, Christian A Klöckner, Artur Marchewka, Małgorzata Wierzba
Climate change is widely recognised as an urgent issue, and the number of people concerned about it is increasing. While emotions are among the strongest predictors of behaviour change in the face of climate change, researchers have only recently begun to investigate this topic experimentally. This may be due to the lack of standardised, validated stimuli that would make studying such a topic in experimental settings possible. Here, we introduce a novel Emotional Climate Change Stories (ECCS) stimuli set. ECCS consists of 180 realistic short stories about climate change, designed to evoke five distinct emotions-anger, anxiety, compassion, guilt and hope-in addition to neutral stories...
April 18, 2024: Behavior Research Methods
https://read.qxmd.com/read/38636919/influencing-factors-and-risk-assessment-of-phthalate-ester-pollution-in-the-agricultural-soil-on-a-tropical-island
#31
JOURNAL ARTICLE
Jinfei Tian, Yibin Qian, Xiaokang He, Ruifang Qi, Jinming Lei, Qixuan Wang, Chenghong Feng
Phthalate esters (PAEs) are widely prevalent in agricultural soil and pose potential risks to crop growth and food safety. However, the current understanding of factors influencing the behavior and fate of PAEs is limited. This study conducted a large-scale investigation (106 sites in 18 counties with 44 crop types) of 16 types of PAEs on a tropical island. Special attention was given to the impacts of land use type, soil environmental conditions, agricultural activity intensity, and urbanization level. The health risks to adults and children from soil PAEs via multiple routes of exposure were also evaluated...
April 16, 2024: Chemosphere
https://read.qxmd.com/read/38636110/a-systematic-review-of-the-mozart-effect-in-adult-and-paediatric-cases-of-drug-resistant-epilepsy-a-sound-approach-to-epilepsy-management
#32
REVIEW
Lucrezia Maria Piccicacchi, Domenico Serino
OBJECTIVES: In recent years, adjunctive therapies for epilepsy management are being explored due to considerable side effects carried by antiepileptic drugs (AEDs) and widespread reports of drug-resistant epilepsy. One such approach is non-invasive musical neurostimulation. Within this context, Mozart's sonata K448 has received particular attention following reports of reduced seizure frequency and a decrease in epileptiform discharges during and after music exposure; often described as the 'Mozart effect'...
April 17, 2024: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38635519/advancing-e-commerce-user-purchase-prediction-integration-of-time-series-attention-with-event-based-timestamp-encoding-and-graph-neural-network-enhanced-user-profiling
#33
JOURNAL ARTICLE
Shuang Zhou, Norlaile Salleh Hudin
In recent years, the global e-commerce landscape has witnessed rapid growth, with sales reaching a new peak in the past year and expected to rise further in the coming years. Amid this e-commerce boom, accurately predicting user purchase behavior has become crucial for commercial success. We introduce a novel framework integrating three innovative approaches to enhance the prediction model's effectiveness. First, we integrate an event-based timestamp encoding within a time-series attention model, effectively capturing the dynamic and temporal aspects of user behavior...
2024: PloS One
https://read.qxmd.com/read/38634940/loneliness-social-isolation-and-obsession-with-covid-19-among-older-adults
#34
JOURNAL ARTICLE
Kayoung Song, Seockhoon Chung
During the COVID-19 pandemic, older people were socially isolated for their protection against the virus impacting their mental health. Aiming to explore the role of loneliness and social isolation in the obsession with COVID-19 among older adults, we conducted an anonymous online survey with 300 older adults aged 65-80 years in South Korea between January and February 2023. The survey collected demographic information, past psychiatric history, medical disease, current psychological distress, and experiences related to COVID-19...
April 18, 2024: Psychiatric Quarterly
https://read.qxmd.com/read/38633777/metabolomics-signatures-of-serotonin-reuptake-inhibitor-escitalopram-serotonin-norepinephrine-reuptake-inhibitor-duloxetine-and-cognitive-behavior-therapy-on-key-neurotransmitter-pathways-in-major-depressive-disorder
#35
Sudeepa Bhattacharyya, Siamak MahmoudianDehkordi, Matthew J Sniatynski, Marina Belenky, Vasant R Marur, A John Rush, W Edward Craighead, Helen S Mayberg, Boadie W Dunlop, Bruce S Kristal, Rima Kaddurah-Daouk
Metabolomics provides powerful tools that can inform about heterogeneity in disease and response to treatments. In this study, we employed an electrochemistry-based targeted metabolomics platform to assess the metabolic effects of three randomly-assigned treatments: escitalopram, duloxetine, and Cognitive Behavior Therapy (CBT) in 163 treatment-naïve outpatients with major depressive disorder. Serum samples from baseline and 12 weeks post-treatment were analyzed using targeted liquid chromatography-electrochemistry for metabolites related to tryptophan, tyrosine metabolism and related pathways...
April 3, 2024: medRxiv
https://read.qxmd.com/read/38633640/identify-the-significant-landscape-characteristics-for-the-perceived-restorativeness-of-8-perceived-sensory-dimensions-in-urban-green-space
#36
JOURNAL ARTICLE
Shiqi Wang, Ang Li
The restorative benefits of urban green spaces (UGSs) have been supported by many studies. Eight perceived sensory dimensions (PSDs) are regarded as a tool to classify green spaces based on perception. However, little attention has been given to the effects of landscape characteristics (LCs) on the perceived restorativeness (PR) of green spaces. Thus, this study aims to clarify this relationship using the eight PSDs. The research collected information, via video stimulus, from 30 participants on the restorative experiences of urban green parks, according to the eight kinds of PSDs...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38632800/exact-fluctuation-and-long-range-correlations-in-a-single-file-model-under-resetting
#37
JOURNAL ARTICLE
Saikat Santra, Prashant Singh
Resetting is a renewal mechanism in which a process is intermittently repeated after a random or fixed time. This simple act of stop and repeat profoundly influences the behavior of a system as exemplified by the emergence of nonequilibrium properties and expedition of search processes. Herein we explore the ramifications of stochastic resetting in the context of a single-file system called random average process (RAP) in one dimension. In particular, we focus on the dynamics of tracer particles and analytically compute the variance, equal time correlation, autocorrelation, and unequal time correlation between the positions of different tracer particles...
March 2024: Physical Review. E
https://read.qxmd.com/read/38632560/potential-of-niacin-skin-flush-response-in-adolescent-depression-identification-and-severity-assessment-a-case-control-study
#38
JOURNAL ARTICLE
Jie Feng, Wenjiao Min, Dandan Wang, Jing Yuan, Junming Chen, Lisha Chen, Wei Chen, Meng Zhao, Jia Cheng, Chunling Wan, Bo Zhou, Yulan Huang, Yaoyin Zhang
BACKGROUND: The diagnosis of adolescent Depressive Disorder (DD) lacks specific biomarkers, posing significant challenges. This study investigates the potential of Niacin Skin Flush Response (NSFR) as a biomarker for identifying and assessing the severity of adolescent Depressive Disorder, as well as distinguishing it from Behavioral and Emotional Disorders typically emerging in childhood and adolescence(BED). METHODS: In a case-control study involving 196 adolescents, including 128 Depressive Disorder, 32 Behavioral and Emotional Disorders, and 36 healthy controls (HCs), NSFR was assessed...
April 17, 2024: BMC Psychiatry
https://read.qxmd.com/read/38632556/study-protocol-exercise-training-for-treating-major-depressive-disorder-in-multiple-sclerosis
#39
JOURNAL ARTICLE
Robert W Motl, Charles H Bombardier, Jennifer Duffecy, Brooks Hibner, Alison Wathen, Michael Carrithers, Gary Cutter
BACKGROUND: Major depressive disorder (MDD) is prevalent, yet sub-optimally treated among persons with multiple sclerosis (MS). We propose that exercise training may be a promising approach for treating depression in persons with MS who have MDD. Our primary hypothesis predicts a reduction in depression severity immediately after an exercise training intervention compared with minimal change in an attention control condition, and the reduction will be maintained during a follow-up period...
April 17, 2024: BMC Neurology
https://read.qxmd.com/read/38630720/inferring-covid-19-testing-and-vaccination-behavior-from-new-jersey-testing-data
#40
JOURNAL ARTICLE
Ari S Freedman, Justin K Sheen, Stella Tsai, Jihong Yao, Edward Lifshitz, David Adinaro, Simon A Levin, Bryan T Grenfell, C Jessica E Metcalf
Characterizing the relationship between disease testing behaviors and infectious disease dynamics is of great importance for public health. Tests for both current and past infection can influence disease-related behaviors at the individual level, while population-level knowledge of an epidemic's course may feed back to affect one's likelihood of taking a test. The COVID-19 pandemic has generated testing data on an unprecedented scale for tests detecting both current infection (PCR, antigen) and past infection (serology); this opens the way to characterizing the complex relationship between testing behavior and infection dynamics...
April 23, 2024: Proceedings of the National Academy of Sciences of the United States of America
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