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https://read.qxmd.com/read/30782268/multidisciplinary-evidence-based-consensus-guidelines-for-human-papillomavirus-hpv-vaccination-in-high-risk-populations-spain-2016
#1
Xavier Martínez-Gómez, Adrian Curran, Magda Campins, Laia Alemany, José Ángel Rodrigo-Pendás, Natalia Borruel, Xavier Castellsagué, Cristina Díaz-de-Heredia, Fernando A Moraga-Llop, Marta Del Pino, Aureli Torné
INTRODUCTION: Although human papillomavirus (HPV) routine vaccination programmes have been implemented around the world and recommendations have been expanded to include other high-risk individuals, current recommendations often differ between countries in Europe, as well as worldwide. AIM: To find and summarise the best available evidence of HPV vaccination in high-risk patients aiding clinicians and public health workers in the day-to-day vaccine decisions relating to HPV in Spain...
February 2019: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://read.qxmd.com/read/30781975/untangling-truth-facts-and-opinions-why-simple-tenets-of-science-have-become-uneasy
#2
Paul E Terry
TIME magazine selected "The Guardians and the War on Truth" as their 2018 "Person of the Year." Journalists everywhere urge us to remember writer Jamal Khashoggi's murder as a harsh testament to the risks of speaking truth to power. But Khashoggi was a perceived threat to a totalitarian government, surely truth is more respected in America, right? Suggest that to the Columbia University School of Law who built a "silencing science tracker" to document "government attempts to restrict or prohibit scientific research, education or discussion...
February 19, 2019: American Journal of Health Promotion: AJHP
https://read.qxmd.com/read/30780129/the-contribution-of-epididymosomes-to-the-sperm-small-rna-profile
#3
REVIEW
Natalie A Trigg, Andrew L Eamens, Brett Nixon
It is now well established that mature spermatozoa harbour a rich and diverse profile of small non-protein coding regulatory RNAs (sRNAs). There is also growing appreciation that this sRNA profile displays considerable plasticity, being altered in response to paternal exposure to a variety of environmental stressors. Coupled with evidence that upon delivery to the oocyte at the moment of fertilisation, sperm-borne sRNAs are able to influence both early embryonic development and the subsequent health of the offspring, there is now interest in both the timing and degree of change in the composition of the sRNA cargo of sperm...
February 1, 2019: Reproduction: the Official Journal of the Society for the Study of Fertility
https://read.qxmd.com/read/30776968/the-british-menopause-society-consensus-statement-on-the-management-of-estrogen-deficiency-symptoms-arthralgia-and-menopause-diagnosis-in-women-treated-for-early-breast-cancer
#4
Jo Marsden, Mike Marsh, Anne Rigg
This guidance document by the British Menopause Society provides an overview of the management of women experiencing estrogen deficiency symptoms and arthralgia following a breast cancer diagnosis. It is now recommended that breast cancer patients are referred to health care professionals with an expertise in menopause for the management of such symptoms, which in turn often involves liaison with patients' breast cancer teams. However, as many women initially present to primary health care professionals for advice, this statement is aimed to support the latter in such consultations by providing information about symptom aetiology, current management strategies and controversies and identifying useful practice points...
February 18, 2019: Post Reproductive Health
https://read.qxmd.com/read/30774189/documenting-archaeological-thin-sections-in-high-resolution-a-comparison-of-methods-and-discussion-of-applications
#5
Magnus M Haaland, Matthias Czechowski, Frank Carpentier, Mathieu Lejay, Bruno Vandermeulen
Optical thin section observations represent the core empirical basis for most micromorphological interpretations at archaeological sites. These observations, which often vary in size and shape, are usually documented through digital graphic representations such as photomicrographs, scans, or figures. Due to variability in documentation practices, however, visual thin section data can be captured with a range of methods and in many different formats and resolutions. In this paper, we compare and evaluate five common image-based methods for documenting thin sections in high-resolution: a flatbed scanner, a film scanner, a macro photography rig, and conventional stereo and light microscopes...
January 2019: Geoarchaeology
https://read.qxmd.com/read/30773387/early-intervention-for-obsessive-compulsive-disorder-an-expert-consensus-statement
#6
Naomi A Fineberg, Bernardo Dell'Osso, Umberto Albert, Giuseppe Maina, Daniel Geller, Lior Carmi, Nick Sireau, Susanne Walitza, Giacomo Grassi, Stefano Pallanti, Eric Hollander, Vlasios Brakoulias, Jose M Menchon, Donatella Marazziti, Konstantinos Ioannidis, Annemieke Apergis-Schoute, Dan J Stein, Danielle C Cath, Dick J Veltman, Michael Van Ameringen, Leonardo F Fontenelle, Roseli G Shavitt, Daniel Costa, Juliana B Diniz, Joseph Zohar
Obsessive-compulsive disorder (OCD) is common, emerges early in life and tends to run a chronic, impairing course. Despite the availability of effective treatments, the duration of untreated illness (DUI) is high (up to around 10 years in adults) and is associated with considerable suffering for the individual and their families. This consensus statement represents the views of an international group of expert clinicians, including child and adult psychiatrists, psychologists and neuroscientists, working both in high and low and middle income countries, as well as those with the experience of living with OCD...
February 14, 2019: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://read.qxmd.com/read/30772445/clinical-value-of-hernia-mesh-pathology-evaluation
#7
Negin Fadaee, Laura Mazer, Rajeev Sharma, Isabel Capati, Bonnie Balzer, Shirin Towfigh
BACKGROUND: Hernia mesh removal is growing in demand. Meanwhile, there is no standard in handling the mesh specimen, nor is there any consensus on the clinical value of the surgical pathology findings. STUDY DESIGN: All hernia mesh specimens gathered from 2013-2018 were analyzed. Patients were categorized based on indication for mesh removal. "Mesh reaction" group included those with clinical reaction deemed to be related to the mesh material. "Mesh non-reaction" group included patients who had mesh removed for a clinical indication unrelated to the mesh material...
February 14, 2019: Journal of the American College of Surgeons
https://read.qxmd.com/read/30772278/development-of-evidence-based-quality-indicators-for-deep-brain-stimulation-in-patients-with-parkinson-s-disease-and-first-year-experience-of-implementation-of-a-nation-wide-registry
#8
Kirsten Haas, Stephanie Stangl, Frank Steigerwald, Cordula Matthies, Doreen Gruber, Andrea A Kühn, Joachim K Krauss, Friederike Sixel-Döring, Kajetan von Eckardstein, Günther Deuschl, Joseph Classen, Dirk Winkler, Jürgen Voges, Imke Galazky, Wolfgang Oertel, Andres O Ceballos-Baumann, Max Lange, Alireza Gharabaghi, Daniel T Weiss, Jens Volkmann, Peter U Heuschmann
INTRODUCTION: Deep Brain Stimulation (DBS) is a complex, invasive and cost-intensive therapy that requires a high level of expertise. To date, data on quality of DBS in clinical routine in the German health care system are lacking. METHODS: The development of evidence-based QIs for DBS in PD patients was performed following a standardized process by a multidisciplinary board between 2014 and 2016. The process was initiated by the German Parkinson Society and followed international recommendations for developing QIs including: a systematic literature search; an appraisal of the published evidence; a consensus-based selection of the QI set; and a pilot study to assess the feasibility in implementing the QIs in clinical routine...
February 5, 2019: Parkinsonism & related Disorders
https://read.qxmd.com/read/30771989/critical-evaluation-of-a-seafast-system-for-the-analysis-of-trace-metals-in-marine-samples
#9
Kathrin Wuttig, Ashley T Townsend, Pier van der Merwe, Melanie Gault-Ringold, Thomas Holmes, Christina Schallenberg, Pauline Latour, Manon Tonnard, Micha J A Rijkenberg, Delphine Lannuzel, Andrew R Bowie
A seawater preconcentration system (seaFAST) with offline sector-field inductively coupled plasma mass spectrometry (SF-ICP-MS) detection was critically evaluated for ultra-low trace elemental analysis of Southern Ocean samples over a four-year period (2015-2018). The commercially available system employs two Nobias PA1 resin columns for buffer cleaning and sample preconcentration, allowing salt matrix removal with simultaneous extraction of a range of trace elements. With a primary focus on method simplicity and practicality, a range of experimental parameters relevant to oceanographic analysis were considered, including reduction of blank levels (over weeks and years), instrument conditioning, extraction efficiencies over different pH ranges (5...
May 15, 2019: Talanta
https://read.qxmd.com/read/30768461/american-society-for-enhanced-recovery-and-perioperative-quality-initiative-joint-consensus-statement-on-perioperative-management-of-patients-on-preoperative-opioid-therapy
#10
David A Edwards, Traci L Hedrick, Jennifer Jayaram, Charles Argoff, Padma Gulur, Stefan D Holubar, Tong J Gan, Michael G Mythen, Timothy E Miller, Andrew D Shaw, Julie K M Thacker, Matthew D McEvoy
Enhanced recovery pathways have quickly become part of the standard of care for patients undergoing elective surgery, especially in North America and Europe. One of the central tenets of this multidisciplinary approach is the use of multimodal analgesia with opioid-sparing and even opioid-free anesthesia and analgesia. However, the current state is a historically high use of opioids for both appropriate and inappropriate reasons, and patients with chronic opioid use before their surgery represent a common, often difficult-to-manage population for the enhanced recovery providers and health care team at large...
February 12, 2019: Anesthesia and Analgesia
https://read.qxmd.com/read/30766843/treatment-of-advanced-nonsmall-cell-lung-cancer-first-line-maintenance-and-second-line-indian-consensus-statement-update
#11
REVIEW
Kumar Prabhash
The management of advanced nonsmall cell lung cancer (NSCLC) patients is becoming increasingly complex with the identification of driver mutations/rearrangements and development/availability of appropriate targeted therapies. In 2017, an expert group of medical oncologists with expertise in treating lung cancer used data from published literature and experience to arrive at practical consensus recommendations on treatment of advanced NSCLC for use by the community oncologists. This was published subsequently in the Indian Journal of Cancer with a plan to be updated annually...
January 2019: South Asian Journal of Cancer
https://read.qxmd.com/read/30766817/clinical-spectrum-of-disorders-of-sex-development-a-cross-sectional-observational-study
#12
Sheeraz A Dar, Mudasir Nazir, Roumissa Lone, Duri Sameen, Ikhlas Ahmad, Wasim A Wani, Bashir A Charoo
Objective: Disorders of sex development (DSD) constitutes a small but difficult and equally important area of endocrinology. It is often a social emergency as the decision regarding sex assignment in these cases is extremely disturbing and difficult to both families and healthcare professionals. Our study was devised to assess the clinical and chromosomal profile of patients with suspected DSD and classify them according to the new DSD consensus document. Subjects and Methods: This study was a cross-sectional observational study carried out in the department of pediatrics of a tertiary care hospital from August 2012 to August 2014...
November 2018: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/30766003/left-circumflex-artery-injury-postmitral-valve-surgery-single-center-experience
#13
Aysha Husain, Aly Alsanei, Mohammed Tahir, Ziad Dahdouh, Zohair AlHalees, Ali AlMasood
The left circumflex (LCX) artery is located close to the mitral valve (MV), making it susceptible to injury during MV surgery. We are reporting our experience in the diagnosis and management of this complication. We retrospectively reviewed our surgical and coronary angiography databases for patients with documented LCX artery injury during MV surgery between January 2000 and December 2016. The complication was associated with MV replacement (9/1313, 0.7%) but not MV repair (0/393, 0.0%). Eight patients (88...
April 2019: Journal of the Saudi Heart Association
https://read.qxmd.com/read/30763119/current-and-common-definitions-of-treatment-resistant-depression-findings-from-a-systematic-review-and-qualitative-interviews
#14
Sage Brown, Katherine Rittenbach, Sarah Cheung, Gail McKean, Frank P MacMaster, Fiona Clement
OBJECTIVE: No universal definition for treatment-resistant depression (TRD) exists. This lack of consensus reduces the generalizability of study findings and limits the ability to study TRD. In addition, anecdotally, there may be a difference between the definitions of TRD within research and those applied in practice. Thus, the objective of this work was to identify current common definitions of TRD used in both research and clinical practice. METHOD: A systematic review of published literature was conducted to document TRD definitions...
February 14, 2019: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://read.qxmd.com/read/30753708/sglt-2-inhibitors-and-glp-1-receptor-agonists-for-nephroprotection-and-cardioprotection-in-patients-with-diabetes-mellitus-and-chronic-kidney-disease-a-consensus-statement-by-the-eureca-m-and-the-diabesity-working-groups-of-the-era-edta
#15
Pantelis Sarafidis, Charles J Ferro, Enrique Morales, Alberto Ortiz, Jolanta Malyszko, Radovan Hojs, Khaled Khazim, Robert Ekart, Jose Valdivielso, Denis Fouque, Gérard M London, Ziad Massy, Petro Ruggenenti, Esteban Porrini, Andrej Wiecek, Carmine Zoccali, Francesca Mallamaci, Mads Hornum
Chronic kidney disease (CKD) in patients with diabetes mellitus (DM) is a major problem of public health. Currently, many of these patients experience progression of cardiovascular and renal disease, even when receiving optimal treatment. In previous years, several new drug classes for the treatment of type 2 DM have emerged, including inhibitors of renal sodium-glucose co-transporter-2 (SGLT-2) and glucagon-like peptide-1 (GLP-1) receptor agonists. Apart from reducing glycaemia, these classes were reported to have other beneficial effects for the cardiovascular and renal systems, such as weight loss and blood pressure reduction...
February 1, 2019: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/30753437/consensus-building-around-nutrition-lessons-from-the-2014-16-ebola-virus-disease-outbreak-in-guinea-and-sierra-leone
#16
Stephen R Kodish, Aline Simen-Kapeu, Jean-Max Beauliere, Ismael Ngnie-Teta, Mohammed B Jalloh, Solade Pyne-Bailey, Helen Schwartz, James P Wirth
There are important lessons learned from the 2014-16 Ebola virus disease outbreak in West Africa. However, there has not been a systematic documentation of nutrition lessons specifically. Therefore, this study sought to generate multiple stakeholder perspectives for understanding the nutrition challenges faced during the Ebola virus disease outbreak, as well as for consensus building around improved response strategies. Participatory workshops with 17 and 19 participants in Guinea and Sierra Leone, respectively, were conducted in February 2017...
February 7, 2019: Health Policy and Planning
https://read.qxmd.com/read/30747702/position-paper-on-laboratory-testing-for-patients-with-haemophilia-a-consensus-document-from-siset-aice-sibioc-and-sipmel
#17
Armando Tripodi, Rita C Santoro, Sophie Testa, Angelo C Molinari, Sergio Bernardini, Maria Golato, Giuseppe Lippi, Walter Ageno, Elena Santagostino
No abstract text is available yet for this article.
February 4, 2019: Blood Transfusion, Trasfusione del Sangue
https://read.qxmd.com/read/30745131/radioiodine-treatment-of-differentiated-thyroid-cancer-related-to-guidelines-and-scientific-literature
#18
M Estorch, M Mitjavila, M A Muros, E Caballero
In differentiated thyroid cancer (DTC), radioiodine is administered to eliminate residual normal thyroid tissue after thyroidectomy (ablative treatment), to treat residual microscopic disease (adjuvant treatment), and to treat macroscopic or metastatic disease. Currently, treatment of DTC with 131 I is still a matter of controversy due to the absence of prospective clinical trials assessing its benefit in terms of overall survival and recurrence-free interval. The current recommendations of the experts are based on observational retrospective data and on their interpretation of the literature...
February 7, 2019: Revista Española de Medicina Nuclear e Imagen Molecular
https://read.qxmd.com/read/30744706/core-outcome-set-standardised-protocol-items-the-cos-stap-statement
#19
Jamie J Kirkham, Sarah Gorst, Douglas G Altman, Jane M Blazeby, Mike Clarke, Sean Tunis, Paula R Williamson
BACKGROUND: Several hundred core outcome set (COS) projects have been systematically identified to date which, if adopted, ensure that researchers measure and report those outcomes that are most likely to be relevant to users of their research. The uptake of a COS by COS users will depend in part on the transparency and robustness of the methods used in the COS development study, which would be increased by the use of a standardised protocol. This article describes the development of the COS-STAP (Core Outcome Set-STAndardised Protocol Items) Statement for the content of a COS development study protocol...
February 11, 2019: Trials
https://read.qxmd.com/read/30742321/the-clinical-role-of-laser-for-vulvar-and-vaginal-treatments-in-gynecology-and-female-urology-an-ics-issvd-best-practice-consensus-document
#20
Mario Preti, Pedro Vieira-Baptista, Giuseppe Alessandro Digesu, Carol Emi Bretschneider, Margot Damaser, Oktay Demirkesen, Debra S Heller, Naside Mangir, Claudia Marchitelli, Sherif Mourad, Micheline Moyal-Barracco, Sol Peremateu, Visha Tailor, Tufan Tarcan, Elise J B De, Colleen K Stockdale
BACKGROUND: The clinical role of LASER for vulvar and vaginal treatments in gynecology and female urology is controversial. AIMS: In this best practice document, we propose recommendations for the use of LASER for gynecologic and urologic conditions such as vulvovaginal atrophy, urinary incontinence, vulvodynia, and lichen sclerosus based on a thorough literature review. MATERIALS & METHODS: This project was developed between January and September 2018...
February 11, 2019: Neurourology and Urodynamics
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