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Hemorrhoid treatment for Crohn’s proctitis

Anna C Juncadella, Amer M Alame, Laurence R Sands, Amar R Deshpande
Perianal involvement in Crohn's disease (CD), which encompasses fistulas, ulcers, abscesses, strictures and cancer, can lead to significant impairment in quality of life. The objective of this article is to review the major perianal complications of CD and the current medical and surgical modalities used to treat them. Antibiotics are commonly used despite a lack of controlled trials to validate their use and should be used as a bridge to maintenance therapy. The anti-metabolites azathioprine and 6-MP have shown a positive response in terms of fistula closure, although these data are mostly from trials looking at this as a secondary endpoint...
April 2015: Postgraduate Medicine
Robert T Lewis, Joshua I S Bleier
Crohn disease involves the perineum and rectum in approximately one-third of patients. Symptoms can range from mild, including skin tags and hemorrhoids, to unremitting and severe, requiring a proctectomy in a small, but significant, portion. Fistula-in-ano and perineal sepsis are the most frequent manifestation seen on presentation. Careful diagnosis, including magnetic resonance imaging or endorectal ultrasound with examination under anesthesia and aggressive medical management, usually with a tumor necrosis factor-alpha, is critical to success...
June 2013: Clinics in Colon and Rectal Surgery
Richelle J F Felt-Bersma, Joep F Bartelsman
Anorectal disorders like haemorrhoids, rectal prolapse, anal fissures, peri-anal fistulae and sexually transmitted diseases are bothersome benign conditions that warrant special attention. They, however, can all be diagnosed by inspection or proctoscopy (sexually transmitted proctitis). Constipation can play an underlying role in haemorrhoids, rectal prolapse and anal fissures, and it is important to treat these conditions in order to avoid recurrences. Haemorrhoids and anal fissures are generally treated conservatively and surgery is seldom required...
2009: Best Practice & Research. Clinical Gastroenterology
Benjamin Person, Steven D Wexner
Perianal manifestations of Crohn's disease usually coexist with active inflammation of other primary sites of the disease. Although treatment of active proximal disease may sometimes alleviate perianal symptoms, it is reasonable to separately treat symptomatic perianal disease. The diversity of perianal manifestations in Crohn's disease mandates a tailored, individualized approach in every case. Medical therapy is the best treatment option for hemorrhoids and anal fissures. The medical management of patients with perianal Crohn's disease includes the use of systemic antibiotics, immunosuppressive agents, and infliximab...
June 2005: Current Treatment Options in Gastroenterology
L K Stewart, J McGee, S R Wilson
OBJECTIVE: Perianal infection arises in small intersphincteric anal glands predominantly located at the dentate line. Documentation of fluid collections and the relationship of inflammatory tracts to the sphincter mechanism is important for surgical treatment. Transanal sonography for assessment of perianal inflammatory disease is limited because placement of the rigid probe into the anal canal does not allow assessment of disease in the perineal region. The purpose of this study was to validate the use of transperineal sonography in men and both transvaginal and transperineal sonography in women for evaluation of perianal inflammatory disease...
September 2001: AJR. American Journal of Roentgenology
K I Myshkin, A I Temnikov, G N Reshetov, S V Dodin
Operations were performed on 865 patients for pararectal fistulas. The fistulas occurred after injury in 18 patients, histological examination revealed fistulous form of Crohn's disease in 14 patients, 12 patients had tuberculous paraproctitis. The late-term results of surgical treatment of chronic paraproctitis were studied in 560 patients according to the presence of concomitant hemorrhoids. One-stage excision of the fistula and hemorrhoidectomy was conducted in 329 patients. The fistula recurred in 1.3% of cases...
February 1990: Khirurgiia
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