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adrenal insufficiency in critical patients critical care medicine

https://read.qxmd.com/read/19325359/clinical-practice-parameters-for-hemodynamic-support-of-pediatric-and-neonatal-septic-shock-2007-update-from-the-american-college-of-critical-care-medicine
#21
JOURNAL ARTICLE
Joe Brierley, Joseph A Carcillo, Karen Choong, Tim Cornell, Allan Decaen, Andreas Deymann, Allan Doctor, Alan Davis, John Duff, Marc-Andre Dugas, Alan Duncan, Barry Evans, Jonathan Feldman, Kathryn Felmet, Gene Fisher, Lorry Frankel, Howard Jeffries, Bruce Greenwald, Juan Gutierrez, Mark Hall, Yong Y Han, James Hanson, Jan Hazelzet, Lynn Hernan, Jane Kiff, Niranjan Kissoon, Alexander Kon, Jose Irazuzta, John Lin, Angie Lorts, Michelle Mariscalco, Renuka Mehta, Simon Nadel, Trung Nguyen, Carol Nicholson, Mark Peters, Regina Okhuysen-Cawley, Tom Poulton, Monica Relves, Agustin Rodriguez, Ranna Rozenfeld, Eduardo Schnitzler, Tom Shanley, Saraswati Kache, Peter Skippen, Adalberto Torres, Bettina von Dessauer, Jacki Weingarten, Timothy Yeh, Arno Zaritsky, Bonnie Stojadinovic, Jerry Zimmerman, Aaron Zuckerberg
BACKGROUND: The Institute of Medicine calls for the use of clinical guidelines and practice parameters to promote "best practices" and to improve patient outcomes. OBJECTIVE: 2007 update of the 2002 American College of Critical Care Medicine Clinical Guidelines for Hemodynamic Support of Neonates and Children with Septic Shock. PARTICIPANTS: Society of Critical Care Medicine members with special interest in neonatal and pediatric septic shock were identified from general solicitation at the Society of Critical Care Medicine Educational and Scientific Symposia (2001-2006)...
February 2009: Critical Care Medicine
https://read.qxmd.com/read/19214457/-corticosteroid-insufficiency-in-the-critically-ill-pathomechanisms-and-recommendations-for-diagnosis-and-treatment
#22
REVIEW
J Briegel, M Vogeser, D Keh, P Marik
Critically ill patients with severe systemic inflammation can develop critical illness-related corticosteroid insufficiency (CIRCI), which is associated with a poor outcome. A task force of the American College of Critical Care Medicine compiled recommendations for diagnosis and treatment of this clinical entity thereby focusing on patients with septic shock and acute respiratory distress syndrome (ARDS). The results of large scale multi-centre trials gave partially conflicting results arguing against the broad use of corticosteroids in stress doses...
February 2009: Der Anaesthesist
https://read.qxmd.com/read/19092649/cardiovascular-manifestations-of-sedatives-and-analgesics-in-the-critical-care-unit
#23
REVIEW
Jamil Darrouj, Lama Karma, Rohit Arora
There are numerous sedatives and analgesics used in critical care medicine today; these medications are used on critically ill patients, many of whom have heart disease, including coronary artery disease or congestive heart failure. The purpose of this review is to recognize the effects of these medications on the heart. Studies that evaluated the effects of sedatives and analgesics on normal individuals or on those with heart disease were reviewed. Current choices for sustained sedation in the critically ill include the benzodiazepines, morphine, propofol, and etomidate...
July 2009: American Journal of Therapeutics
https://read.qxmd.com/read/18644822/is-steroid-therapy-ever-of-benefit-to-patients-in-the-intensive-care-unit-going-into-septic-shock
#24
REVIEW
Lydia Richardson, Steven Hunter
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, is steroid therapy ever of benefit to patients in the intensive care unit going into septic shock? Using the reported search 1505 papers were identified. Fourteen papers represented the best evidence on the subject. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results and study comments and weaknesses were tabulated. Recent guidelines from the Surviving Sepsis Campaign recommend using stress doses of corticosteroids for septic shock regardless of adrenal function...
October 2008: Interactive Cardiovascular and Thoracic Surgery
https://read.qxmd.com/read/18499615/free-cortisol-in-sepsis-and-septic-shock
#25
MULTICENTER STUDY
Stepani Bendel, Sari Karlsson, Ville Pettilä, Pekka Loisa, Marjut Varpula, Esko Ruokonen
BACKGROUND: Severe sepsis activates the hypothalamopituitary axis, increasing cortisol production. In some studies, hydrocortisone substitution based on an adrenocorticotropic hormone-stimulation test or baseline cortisol measurement has improved outcome. Because only the free fraction of cortisol is active, measurement of free cortisol may be more important than total cortisol in critically ill patients. We measured total and free cortisol in patients with severe sepsis and related the concentrations to outcome...
June 2008: Anesthesia and Analgesia
https://read.qxmd.com/read/18496365/recommendations-for-the-diagnosis-and-management-of-corticosteroid-insufficiency-in-critically-ill-adult-patients-consensus-statements-from-an-international-task-force-by-the-american-college-of-critical-care-medicine
#26
JOURNAL ARTICLE
Paul E Marik, Stephen M Pastores, Djillali Annane, G Umberto Meduri, Charles L Sprung, Wiebke Arlt, Didier Keh, Josef Briegel, Albertus Beishuizen, Ioanna Dimopoulou, Stylianos Tsagarakis, Mervyn Singer, George P Chrousos, Gary Zaloga, Faran Bokhari, Michael Vogeser
OBJECTIVE: To develop consensus statements for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients. PARTICIPANTS: A multidisciplinary, multispecialty task force of experts in critical care medicine was convened from the membership of the Society of Critical Care Medicine and the European Society of Intensive Care Medicine. In addition, international experts in endocrinology were invited to participate. DESIGN/METHODS: The task force members reviewed published literature and provided expert opinion from which the consensus was derived...
June 2008: Critical Care Medicine
https://read.qxmd.com/read/18158437/surviving-sepsis-campaign-international-guidelines-for-management-of-severe-sepsis-and-septic-shock-2008
#27
JOURNAL ARTICLE
R Phillip Dellinger, Mitchell M Levy, Jean M Carlet, Julian Bion, Margaret M Parker, Roman Jaeschke, Konrad Reinhart, Derek C Angus, Christian Brun-Buisson, Richard Beale, Thierry Calandra, Jean-Francois Dhainaut, Herwig Gerlach, Maurene Harvey, John J Marini, John Marshall, Marco Ranieri, Graham Ramsay, Jonathan Sevransky, B Taylor Thompson, Sean Townsend, Jeffrey S Vender, Janice L Zimmerman, Jean-Louis Vincent
OBJECTIVE: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," published in 2004. DESIGN: Modified Delphi method with a consensus conference of 55 international experts, several subsequent meetings of subgroups and key individuals, teleconferences, and electronic-based discussion among subgroups and among the entire committee. This process was conducted independently of any industry funding...
January 2008: Critical Care Medicine
https://read.qxmd.com/read/18058085/surviving-sepsis-campaign-international-guidelines-for-management-of-severe-sepsis-and-septic-shock-2008
#28
JOURNAL ARTICLE
R Phillip Dellinger, Mitchell M Levy, Jean M Carlet, Julian Bion, Margaret M Parker, Roman Jaeschke, Konrad Reinhart, Derek C Angus, Christian Brun-Buisson, Richard Beale, Thierry Calandra, Jean-Francois Dhainaut, Herwig Gerlach, Maurene Harvey, John J Marini, John Marshall, Marco Ranieri, Graham Ramsay, Jonathan Sevransky, B Taylor Thompson, Sean Townsend, Jeffrey S Vender, Janice L Zimmerman, Jean-Louis Vincent
OBJECTIVE: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock," published in 2004. DESIGN: Modified Delphi method with a consensus conference of 55 international experts, several subsequent meetings of subgroups and key individuals, teleconferences, and electronic-based discussion among subgroups and among the entire committee. This process was conducted independently of any industry funding...
January 2008: Intensive Care Medicine
https://read.qxmd.com/read/17417118/identification-of-adrenal-insufficiency-in-pediatric-critical-illness
#29
JOURNAL ARTICLE
Kusum Menon, Margaret Lawson
OBJECTIVE: To determine physicians' beliefs and practices regarding adrenal dysfunction in pediatric critical illness. DESIGN: Cross-sectional mail survey. SETTING: Canada. PARTICIPANTS: All members of the Canadian Pediatric Endocrine Group and all physicians identified as practicing pediatric intensive care medicine in any of 16 tertiary care teaching centers in Canada. INTERVENTIONS: Three pediatric intensive care physicians and three pediatric endocrinologists reviewed the questionnaire before administration to ensure clarity...
May 2007: Pediatric Critical Care Medicine
https://read.qxmd.com/read/15616387/the-immunoneuroendocrine-axis-in-critical-illness-beneficial-adaptation-or-neuroendocrine-exhaustion
#30
REVIEW
Albertus Beishuizen, Lambertus G Thijs
PURPOSE OF REVIEW: Over the last years, endocrinology has been incorporated in critical care medicine, and acknowledgment of the complex neuro-endocrine adaption of critical illness has led to new insights and major breakthroughs in clarifying pathophysiological mechanisms and the targeting of therapeutic strategies. This review focuses on the important role of the hypothalamic-pituitary-adrenal (HPA) axis during critical illness and the occurrence of neuroendocrine failure. RECENT FINDINGS: The distinction between acute (activated anterior pituitary function and inactivated peripheral anabolic pathways) and prolonged (reduced neuroendocrine stimulation) critical illness as different neuroendocrine paradigms has brought a new approach to the critically ill patient...
December 2004: Current Opinion in Critical Care
https://read.qxmd.com/read/12194394/an-evidence-based-review-on-the-use-of-corticosteroids-in-peri-operative-and-critical-care
#31
REVIEW
Yin-Yi Han, Wei-Zen Sun
With complex and extensive pharmacological effects, corticosteroids are widely used in many clinical situations. A survey conducted to define the role of corticosteroids in various settings of peri-operative and critical care gave strong evidence to support that the use of corticosteroid is absolutely indicated in patients with adrenal insufficiency, asthma, anaphylaxis, acute spinal cord injury, and increased ICP resulting from brain tumors. As the benefits of corticosteroids are much in evidence, their uses are recommended to extend to postoperative antiemesis, acute respiratory failure (such as ARDS, COPD, and fat embolism), increased ICP associated with brain abscess, thyroid storm, and refractory hypothermia...
June 2002: Acta Anaesthesiologica Sinica
https://read.qxmd.com/read/8905423/a-comparison-of-the-adrenocortical-response-during-septic-shock-and-after-complete-recovery
#32
COMPARATIVE STUDY
J Briegel, G Schelling, M Haller, W Mraz, H Forst, K Peter
OBJECTIVE: To compare the adrenocortical response to corticotropin during septic shock and after complete recovery. DESIGN: Prospective clinical study. SETTING: Multidisciplinary intensive care unit in a university hospital. PATIENTS: 20 consecutive patients surviving septic shock. All patients met the American College of Chest Physicians/Society of Critical Care Medicine criteria for septic shock. In addition, the presence of high-output circulatory failure with a cardiac index > 41/min per m2 was a criterion for enrollment in the study...
September 1996: Intensive Care Medicine
https://read.qxmd.com/read/6422560/endocrine-metabolic-emergencies
#33
REVIEW
D R Rush, S C Hamburger
Endocrine metabolic emergencies are common clinical entities seen by most health care professionals in acute care medicine. Except for cardiopulmonary arrest, few situations require such rapid institution of immediate drug therapy to reverse life-threatening metabolic imbalances. To safely guide patients through these situations, the physician requires a basic knowledge and familiarity with the approaches, indications, and limitations of drug therapy as a component of care.
February 1984: Southern Medical Journal
https://read.qxmd.com/read/1862960/-intensive-therapy-in-syndromes-of-disorders-of-cerebral-blood-circulation-in-the-bed-of-the-anterior-cerebral-arteries-following-the-removal-of-middle-basal-tumors
#34
JOURNAL ARTICLE
V G Amcheslavskiĭ, N A Dziubanova, S A Lobanov, A G Korshunov, V P Kulikovskiĭ
255 patients have been examined in the early postoperative period after the removal of tumors located in diencephalic and sella turcica regions. The early postoperative period was complicated by circulation disturbances in the vascular bed of the anterior cerebral or anterior communicative arteries. The clinical pattern, CT scans and morphological data were analysed. Three principal clinical syndromes of the postoperative period were lined out: 1) extrapyramidal-diencephalic syndrome; 2) extrapyramidal-capsular syndrome; 3) frontal-corpocallosal syndrome...
January 1991: Anesteziologiia i Reanimatologiia
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