V N Anisimov, V Kh Khavinson, N Iu Zavarzina, M A Zabezhinskiĭ, O A Zimina, I G Popovich, A V Shtylik, A V Arutiunian, T I Oparina, V M Prokopenko
Female CBA mice were injected with s.c. synthetic tetrapeptide Epithalon from a 6-month age until death. The drug failed to affect the body weight or food consumption, physical activity or behavioural parameters. However, it slowed down the age-related switching off of the estrus function, decreased body temperature, decelerated free redical processes, prolonged the mice life span with an accompanying drop in spontaneous tumour incidence.
January 2001: Rossiĭskii Fiziologicheskiĭ Zhurnal Imeni I.M. Sechenova