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Chunji Chen, Yiyang Wang, Xufeng Pan, Shijie Fu, Yubo Shi, Jun Yang, Rui Wang
Background: We tried to explore the surgical procedures for stage I squamous cell carcinoma (SCC) with a size of ≤3 cm by using the Surveillance, Epidemiology, and End Results (SEER) database. Furthermore, we investigated the relationships between the chosen surgical option and the size of SCC. Methods: In total, 1,147 patient data sets were collected from 2010 to 2011 using the SEER database. Afterwards, 849 patients with a pT1-2aN0M0 SCC with a size of ≤3 cm after a lobectomy or sublobectomy procedure were identified...
December 2018: Journal of Thoracic Disease
Yang Wo, Yandong Zhao, Tong Qiu, Shicheng Li, Yuanyong Wang, Tong Lu, Yi Qin, Guisong Song, Shuncheng Miao, Xiao Sun, Ao Liu, Dezhi Kong, Yanting Dong, Xiaoliang Leng, Wenxing Du, Wenjie Jiao
Visceral pleural invasion (VPI) has been identified as an adverse prognostic factor for non-small cell lung cancer (NSCLC). Accurate nodal staging for NSCLC correlates with improved survival, but it is unclear whether tumors with VPI require a more extensive lymph nodes (LNs) dissection to optimize survival. We aimed to evaluate the impact of VPI status on the optimal extent of LNs dissection in stage I NSCLC, using the Surveillance, Epidemiology, and End Results (SEER) database. We identified 9297 surgically treated T1-2aN0M0 NSCLC patients with at least one examined LNs...
February 1, 2019: Cancer Medicine
Hongdou Ding, Haifeng Wang, Li Xu, Nan Song, Gening Jiang
BACKGROUND: To investigate the association between survival and the number of examined lymph nodes following sublobar resection for node-negative non-small cell lung cancer ≤2 cm. METHODS: The Surveillance, Epidemiology, and End Results database was used to identify patients diagnosed with non-small cell lung cancer ≤2 cm from 2004 to 2014 and underwent wedge resection or segmentectomy. Patients were stratified by the procedure (wedge resection, segmentectomy), the size of tumors (≤1 cm, 1-2 cm) and the number of lymph nodes examined (0, 1-3, 4-9, 10+)...
January 22, 2019: Annals of Thoracic Surgery
Xiaodong Yang, Cheng Zhan, Ming Li, Yiwei Huang, Mengnan Zhao, Xinyu Yang, Zongwu Lin, Yu Shi, Wei Jiang, Qun Wang
BACKGROUND: The optimal surgical approach for metachronous second primary lung cancer (MSPLC) has not been well established yet. In this study, survival outcome of lobectomy was compared with sublobectomy for MSPLC. METHODS: A retrospective study was conducted based on the Surveillance, Epidemiology, and End Results database. Propensity score matching was used to reduce the potential bias caused by the variance of the clinicopathologic features of the first and second lung cancer...
September 2018: Annals of Thoracic Surgery
Yiwei Huang, Xiaodong Yang, Tao Lu, Ming Li, Mengnan Zhao, Xingyu Yang, Ke Ma, Shuai Wang, Cheng Zhan, Yu Liu, Qun Wang
Previous studies have identified potential risk factors for pulmonary carcinoid tumors and evaluated the effect of various treatments; however, the results were not entirely consistent. We conducted a population-based study to further explore relevant prognostic issues. We extracted cases with pulmonary carcinoid tumors from the Surveillance Epidemiology and End Results database. Cox proportional hazard regression was utilized to identify potential significant risk factors, which helped establish a nomogram for predicting long-term survival...
June 2018: Cancer Medicine
Haikang Zeng, Yang Liu, Xiaojun Xia, Jin Li, Jianxing He
BACKGROUND: Currently, the prognosis of lobectomy and sub-lobectomy for the treatment of stage Ia small cell lung cancer (SCLC) is rarely reported. We retrospectively studied T1N0M0 (≤3 cm) SCLC patients aged ≥60 years, aiming to comparatively analyze the prognosis of lobectomy and sub-lobectomy in treating patients with Ia SCLC. METHODS: Patients with stage Ia SCLC diagnosed by pathologic between 1992 and 2010 were selected from the "Surveillance, Epidemiology and End Results database"(SEER)...
January 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Haiping Yang, Yaofeng Yun, Yu Mao
The present study investigated and analyzed the clinical impact of sublobectomy on pulmonary functions.Changes in pulmonary function before and after sublobectomy were compared to the changes after lobectomy.Changes in the pulmonary function before and after sublobectomy and lobectomy did not exhibit remarkable differences in long-term effects. Surgery-related indexes of the sublobectomy group were significantly lower than those of the lobectomy group (P < .05). The indexes of pulmonary function both before and after surgery in the sublobectomy group were not associated with a significant decrease in the quality of survival based on pulmonary function as the main index (P > ...
December 2017: Medicine (Baltimore)
Siyuan Dong, Lin Zhang
Lung cancer continues to be one of the leading causes of cancer-related mortality worldwide and its incidence is still increasing. With aging population and development in imaging technology, many more elderly with early-stage lung cancers are being diagnosed than in the past. Lobectomy and sub-lobar resection are two main surgical approach for the treatment for this kind of patients. This review aimed to compare these two methods for this hot issue.
October 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Jian Li, Yongsheng Zhao, Chuan Li, Longfei Zhu, Chengwu Liu, Lunxu Liu
OBJECTIVES: The 8th edition TNM lung cancer classification was enacted in January 2017. An important change is the old T2a was revised to new T2a and T2b. Whether a postoperative survival difference exists between the two stages is still undefined. The purpose of this study is to investigate the postoperative outcomes of small cell lung cancer (SCLC) patients and compare the survival difference between the two stages. METHODS: Data of patients with SCLC who underwent surgery between October 2005 and August 2013 at our institute were reviewed...
December 2017: International Journal of Surgery
Todd A Pezzi, Abdallah S R Mohamed, Clifton D Fuller, Pierre Blanchard, Christopher Pezzi, Boris Sepesi, Stephen M Hahn, Daniel R Gomez, Stephen G Chun
BACKGROUND: The 1998 post-operative radiotherapy meta-analysis for lung cancer showed a survival detriment associated with radiation for stage I-II resected non-small cell lung cancer (NSCLC), but has been criticized for including antiquated radiation techniques. We analyzed the National Cancer Database (NCDB) to determine the impact of radiation after margin-negative (R0) resection for stage I-II NSCLC on survival. METHODS: Adult patients from 2004 to 2014 were analyzed from the NCDB with respect to receiving radiation as part of their first course of treatment for resected stage I-II NSCLC; the primary outcome measure was overall survival...
May 2017: Annals of Surgical Oncology
Joachim Widder, Caroline Van De Wauwer, Johannes A Langendijk
No abstract text is available yet for this article.
February 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Chen Qiu, Guanghui Wang, Jun Xu, Lixuan Cui, Wei Dong, Yang Ni, Xiao Qu, Jiajun Du
OBJECTIVE: The aim of our study was to compare the operative characteristics and long term survival for elderly patients with stage I non-small cell lung cancer (NSCLC) who underwent sublobectomy versus lobectomy. METHODS: We identified 245 consecutive elderly patients (≥65y) with pathologic stage I NSCLC who underwent lobectomy or sublobectomy at our institution between 2006 and 2012, and assessed the operative characteristics, recurrence, and survival differences between these approaches...
January 2017: International Journal of Surgery
Quanxing Liu, Hongmei Wang, Dong Zhou, Xufeng Deng, Jiaxin Min, Jigang Dai
BACKGROUND: Although lobectomy has long been considered the standard procedure for Stage I nonsmall cell lung cancer (NSCLC), the selection of sublobectomy for Stage I NSCLC remains controversial. Amidst growing enthusiasm for minimally invasive surgery, the comparison of clinical outcomes after thoracoscopic sublobectomy versus thoracoscopic lobectomy may be of immense value. OBJECTIVE: The present study aimed to compare the overall survival (OS) and disease-free survival (DFS) outcomes of patients who underwent thoracoscopic sublobectomy with those who underwent thoracoscopic lobectomy for Stage I NSCLC...
April 2016: Journal of Cancer Research and Therapeutics
Jun Wang, Hui Zhao
With advances in medical technology, theproportion of early-stage lung cancerhas been growing. Conforming to the trend of individualized treatment, sublobar resection for early stage lung cancer has been considered more valuable than ever before. Currently, there were still confilictions about the oncological validity of sublobar resection comparing with lobectomy for lung cancer. We reviewed the study status of the following contentious issues: the evidence based medicine, the indications of wedge resection or segmentectomy, the weight of tumor diameter and margin distance, and the choices for the elderly...
June 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Deruo Liu, Zhenrong Zhang
With the widely application of chest computed tomography (CT) and gradual generalization of lung cancer screening project for high risk populations, more and more "tiny lung cancers" were identified. Due to the difficulty in intraoperative orientation, their less aggressiveness, and excellent short/long term prognosis, the 'tiny lung cancers' posed new challenges for the surgery in the treatment of lung cancer. In this review, theirfore, we focused on these challenges and presented the progress in lung cancer screening, orientation of lung nodules, lobectomy and sublobectomy, and lymph node dissection...
June 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Yutian Lai, Heng Du, Xin Wang, Cheng Shen, Jian Huang, Weiming Li, Guowei Che
To investigate the association between the clinical characteristics and clinical modes of surgically treated lung cancer patients, we conducted a retrospective study with 1097 lung cancer patients receiving pulmonary resection between 2012 and 2013.A physical examination or screening (PES) group (n = 267) and a symptomatic (SY) group (n = 830) were established depending on the new clinical mode (sequence of physical examination, early detection and sequential medical treatment) and the conventional mode (hospitalization due to occurrence of relevant symptoms), respectively...
January 2016: Medicine (Baltimore)
Gening Jiang, Dong Xie
The incidence of ground-glass opacity (GGO)-dominant lung cancer is rising in China. The review is focused on the diagnosis and therapy for GGO-dominant lung cancer. CT screening in high-risk groups is recommended for early diagnosis of GGO-dominant lung cancer. The early diagnosis of GGO-dominant lung cancer depends on dynamic observation on the chest CT. Non-surgical biopsy or PET/CT has limited diagnostic value in GGO-dominant lung cancer. Video-assisted Thoracoscopic resection (VATS) is the mainstream treatment for GGO-dominant lung cancer...
October 1, 2015: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Ju-Wei Mu, Shu-Geng Gao, Qi Xue, Jun Zhao, Ning Li, Kun Yang, Kai Su, Zhu-Yang Yuan, Jie He
BACKGROUND: Both uniportal and triportal thoracoscopic lobectomy and sublobectomy are feasible for early-stage non-small cell lung cancer (NSCLC). The aim of this study was to compare the perioperative outcomes of uniportal and triportal thoracoscopic lobectomy and sublobectomy for early-stage NSCLC. METHODS: A total of 405 patients with lung lesions underwent thoracoscopic lobectomy or sublobectomy through a uniportal or triportal procedure in approximately 7-month period (From November 2014 to May 2015)...
October 20, 2015: Chinese Medical Journal
Hui Zhang, Yang Shen-Tu
No abstract text is available yet for this article.
September 20, 2015: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Hiromitsu Domen, Kichizo Kaga, Yasuhiro Hida, Naotake Honma, Reiko Kubota, Yuki Yagi, Yoshiro Matsui
BACKGROUND: According to the aging in Japan, surgery of lung cancer with cardiovascular disease is increasing. Among them, the merger of the heart and large blood vessel disease would be expected to be directly linked to the perioperative management. MATERIALS AND METHODS: We conducted a retrospective analysis of 1,005 patients who had undergone surgical resection of primary lung adenocarcinoma between January 1997 and June 2014 at Hokkaido University Hospital. Among them, 81 patients had more than one cardiovascular disease...
April 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
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