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Disorganized speech

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https://read.qxmd.com/read/30870626/short-clinically-based-prediction-model-to-forecast-transition-to-psychosis-in-individuals-at-clinical-high-risk-state
#1
Magdalena Kotlicka-Antczak, Michał S Karbownik, Konrad Stawiski, Agnieszka Pawełczyk, Natalia Żurner, Tomasz Pawełczyk, Dominik Strzelecki, Paolo Fusar-Poli
OBJECTIVE: The predictive accuracy of the Clinical High Risk criteria for Psychosis (CHR-P) regarding the future development of the disorder remains suboptimal. It is therefore necessary to incorporate refined risk estimation tools which can be applied at the individual subject level. The aim of the study was to develop an easy-to use, short refined risk estimation tool to predict the development of psychosis in a new CHR-P cohort recruited in European country with less established early detection services...
March 11, 2019: European Psychiatry: the Journal of the Association of European Psychiatrists
https://read.qxmd.com/read/30859979/57-pareidolia-as-a-manifestation-of-folie-%C3%A3-deux
#2
Monica Khokhar, Allan Richard Hirsch
IntroductionThe spreading of pareidolia, the visualization of one image inside another image, from one member of a couple to another one is seen in a subtype of folie á deux called folie imposée.Case studyA 27 year old right handed male started having delusions two years prior to presentation. He experienced marked hallucinations in which he saw faces imbedded in clothing and demon-like faces that would appear in curtain shades. During his visual hallucinations, "demonic-like angles would tell me how to get to heaven...
February 2019: CNS Spectrums
https://read.qxmd.com/read/30766437/psychotropic-drug-prescribing-correlates-of-disorganized-speech-in-asians-with-schizophrenia-the-reap-ap-study
#3
Yong Chon Park, Min-Soo Lee, Tian-Mei Si, Helen F K Chiu, Shigenobu Kanba, Mian-Yoon Chong, Adarsh Tripathi, Pichet Udomratn, Kok Yoon Chee, Andi J Tanra, Golam Rabbani, Afzal Javed, Samudra Kathiarachchi, Win Aung Myint, Tran Van Cuong, Kang Sim, Shu-Yu Yang, Norman Sartorius, Chay-Hoon Tan, Naotaka Shinfuku, Seon-Cheol Park
Background: Although disorganized speech is seen as one of the nuclear features of schizophrenia, there have been few reports of disorganized speech-associated psychotropic drug-prescribing patterns in large samples of schizophrenia patients. Objective: We aimed to examine the prevalence of disorganized speech and its correlates in terms of psychotropic drug prescribing, using the data from the Research on Asian Psychotropic Patterns for Antipsychotics (REAP-AP) study...
February 2019: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/30762376/exploring-the-racial-diagnostic-bias-of-schizophrenia-using-behavioral-and-clinical-based-measures
#4
Elana K Schwartz, Nancy M Docherty, Gina M Najolia, Alex S Cohen
There is evidence that African Americans are 2.4 times more likely to be diagnosed with a schizophrenia-spectrum diagnosis compared with White individuals, who are more likely to receive an affective diagnosis. The reason for these diagnostic discrepancies is unclear, however, 2 explanations have garnered attention: epigenetic differences and systematic error or bias in the diagnostic process. The latter is the focus of the present study and it is hypothesized that the bias involves cultural insensitivity on the part of the clinician...
February 14, 2019: Journal of Abnormal Psychology
https://read.qxmd.com/read/30699217/schizoaffective-disorder-a-review
#5
Jacob N Miller, Donald W Black
BACKGROUND: Schizoaffective disorder (SAD) is a chronic, potentially disabling psychotic disorder common in clinical settings. SAD often has been used as a diagnosis for individuals having an admixture of mood and psychotic symptoms whose diagnosis is uncertain. Its hallmark is the presence of symptoms of a major mood episode (either a depressive or manic episode) concurrent with symptoms characteristic of schizophrenia, such as delusions, hallucinations, or disorganized speech. METHODS: A literature search in PubMed and Google Scholar was conducted to identify articles on SAD...
February 2019: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://read.qxmd.com/read/30635257/comparison-of-self-report-and-clinician-rated-schizotypal-traits-in-schizotypal-personality-disorder-and-community-controls
#6
Chi C Chan, Andrea Bulbena-Cabre, Sarah Rutter, Caridad Benavides, Margaret M McClure, William Calabrese, Daniel R Rosell, Harold W Koenigsberg, Marianne Goodman, Antonia S New, Erin A Hazlett, M Mercedes Perez-Rodriguez
Given the common use of self-report questionnaires to assess schizotypy in personality pathology and schizophrenia research, it is important to determine the concordance between self-report and clinician ratings. 250 individuals with schizotypal personality disorder (SPD) and 116 community controls (CTR) were assessed on schizotypal traits using a clinical interview, the Structured Interview for DSM-IV Personality disorders (SIDP), and a self-report questionnaire, the Schizotypal Personality Questionnaire (SPQ)...
January 8, 2019: Schizophrenia Research
https://read.qxmd.com/read/30531913/the-maturation-of-speech-structure-in-psychosis-is-resistant-to-formal-education
#7
Natália Bezerra Mota, Mariano Sigman, Guillermo Cecchi, Mauro Copelli, Sidarta Ribeiro
Discourse varies widely with age, level of education, and psychiatric state. Word graphs have been recently shown to provide behavioral markers of formal thought disorders in psychosis (e.g., disorganized flow of ideas) and to track literacy acquisition in children with typical development. Here we report that a graph-theoretical computational analysis of verbal reports from subjects spanning 6 decades of age and 2 decades of education reveals asymptotic changes over time that depend more on education than age...
December 7, 2018: NPJ Schizophrenia
https://read.qxmd.com/read/30488088/-impairments-of-language-and-communication-in-schizophrenia
#8
REVIEW
Stefan Heim, Maike Dehmer, Merle Berger-Tunkel
Disorganized speech is one of the key symptoms of schizophrenia. This article provides an overview of those areas of speech and communication impaired in patients with schizophrenia. Moreover, the state of the art of behavioral interventions is summarized. In conclusion, more well-controlled speech-language therapy studies are required in order to improve participation and communication-related quality of life in schizophrenia.
November 28, 2018: Der Nervenarzt
https://read.qxmd.com/read/30370855/biperiden-induced-delirium-in-a-five-years-old-child
#9
Duygu Kınay, Ahmet Zihni Soyata
OBJECTIVE: Extrapyramidal adverse effects of antipsychotic drugs are more reported in children. Biperiden is an anticholinergic agent to treat the adverse effects of antipsychotic drugs. The drug has the potential to induce delirium at toxic doses. However, data are scarce about delirium associated with biperiden in children. Thus far, a case of delirium has been associated with biperiden in an adolescent patient. We report the first case of delirium associated with use of biperiden in a preadolescent patient...
October 28, 2018: Current Drug Safety
https://read.qxmd.com/read/30350367/on-making-sense-an-exploration-of-wundt-s-apperceptionist-account-of-meaningful-speech
#10
Liesbet De Kock
In the wake of the critical reorientation in the historiography of psychology, a number of scholars challenged the one-sided structuralist and positivist interpretation of Wilhelm Wundt's work. This paper aims at contributing to these recent efforts, by providing an analysis of the way in which Wundt's apperceptionism conditioned his account of the relation between thought and speech, and by extrapolation, of disorganized thought and speech. While Wundt's pivotal role in the development of the psychology of language is relatively well-known, discussions on this part of his theorizing tend to focus exclusively on his gestural or motor account of language...
October 2018: Journal of the History of the Behavioral Sciences
https://read.qxmd.com/read/30292069/incidence-of-postoperative-delirium-in-elderly-ambulatory-patients-a-prospective-evaluation-using-the-fam-cam-instrument
#11
Antoine G M Aya, Pierre-Henri Pouchain, Hubert Thomas, Jacques Ripart, Philippe Cuvillon
BACKGROUND: While the incidence of postoperative delirium is high in aged hospitalized patients undergoing major surgery, little is known concerning patients undergoing ambulatory surgery. OBJECTIVE: To determine the incidence of postoperative delirium in aged patients after hospital discharge from an ambulatory surgery unit. DESIGN: Prospective observational study. PATIENTS: Elderly patients (≥75 years) scheduled for a surgical procedure on an ambulatory basis...
October 3, 2018: Journal of Clinical Anesthesia
https://read.qxmd.com/read/30232371/the-language-profile-of-formal-thought-disorder
#12
Derya Çokal, Gabriel Sevilla, William Stephen Jones, Vitor Zimmerer, Felicity Deamer, Maggie Douglas, Helen Spencer, Douglas Turkington, Nicol Ferrier, Rosemary Varley, Stuart Watson, Wolfram Hinzen
Formal thought disorder (FTD) is clinically manifested as disorganized speech, but there have been only few investigations of its linguistic properties. We examined how disturbance of thought may relate to the referential function of language as expressed in the use of noun phrases (NPs) and the complexity of sentence structures. We used a comic strip description task to elicit language samples from 30 participants with schizophrenia (SZ), 15 with moderate or severe FTD (SZ + FTD), and 15 minimal or no FTD (SZ-FTD), as well as 15 first-degree relatives of people with SZ (FDRs) and 15 neurotypical controls (NC)...
September 19, 2018: NPJ Schizophrenia
https://read.qxmd.com/read/30220245/psychosis-literacy-among-latinos-with-first-episode-psychosis-and-their-caregivers
#13
Steven R López, Diana Gamez, Yesenia Mejia, Vanessa Calderon, Daisy Lopez, Jodie B Ullman, Alex Kopelowicz
OBJECTIVE: The study examined psychosis literacy among Latinos with first-episode psychosis (FEP) and their caregivers. The authors tested a model that knowledge of psychosis and attribution of illness to psychosis predicted professional help seeking in a cross-sectional design. METHODS: The sample (N=148) consisted of 79 Latino consumers who met criteria for a clinical diagnosis of a psychotic disorder and 69 family caregivers. Participants watched a four-minute narrative about a woman with psychosis and were asked to identify the symptoms of serious mental illness (knowledge of psychosis), describe the character's problem and whether she had a serious mental illness (illness attribution), and offer suggestions about what the parents should do (help seeking)...
September 17, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
https://read.qxmd.com/read/30196235/disorganized-and-unresolved-states-in-adulthood
#14
REVIEW
Deborah Jacobvitz, Samantha Reisz
Fear plays a central role in attachment theory and disorganization in adulthood. Fear associated with traumatic memories interferes with resolution of trauma resulting in disorganized mental states, captured as unresolved/disorganized speech surrounding loss and/or abuse in the Adult Attachment Interview. Mothers who are unresolved experience fear stemming from traumatic memories and display frightening behavior towards their infants. Disorganization can predispose individuals to dissociative mental processes, including altered states (absorption), PTSD, and depersonalization...
February 2019: Current Opinion in Psychology
https://read.qxmd.com/read/30158885/do-patients-with-depression-prefer-literal-or-metaphorical-expressions-for-internal-states-evidence-from-sentence-completion-and-elicited-production
#15
Christina Kauschke, Nadine Mueller, Tilo Kircher, Arne Nagels
In everyday communication metaphoric expressions are frequently used to refer to abstract concepts, such as feelings or mental states. Patients with depression are said to prefer literal over figurative language, i.e. they may show a concreteness bias. Given that both emotional functioning and the processing of figurative language may be altered in this clinical population, our study aims at investigating whether and how these dysfunctions are reflected in the understanding and production of metaphorical expressions for internal states...
2018: Frontiers in Psychology
https://read.qxmd.com/read/30106267/successful-treatment-of-psychosis-in-dentatorubral-pallidoluysian-atrophy-with-quetiapine-a-case-report
#16
Zui Narita, Tomiki Sumiyoshi
INTRODUCTION: Patients with dentatorubral-pallidoluysian atrophy (DRPLA) sometimes elicit psychosis. First-generation antipsychotic drugs have been reported to be effective in treating psychotic symptoms associated with the disease. However, little information is available on the benefits of second-generation antipsychotic drugs (SGAs). CASE: We report on a 47-year-old man with DRPLA whose psychotic symptoms were effectively treated with quetiapine, one of the SGAs...
March 2018: Neuropsychopharmacology Reports
https://read.qxmd.com/read/30022955/cortical-gray-matter-loss-augmented-vulnerability-to-speech-on-speech-masking-and-delusion-in-people-with-schizophrenia
#17
Chao Wu, Yingjun Zheng, Juanhua Li, Shenglin She, Hongjun Peng, Liang Li
People with schizophrenia exhibit impairments in target-speech recognition (TSR) against multiple-talker-induced informational speech masking. Up to date, the underlying neural mechanisms and its relationships with psychotic symptoms remain largely unknown. This study aimed to investigate whether the schizophrenia-associated TSR impairment contribute to certain psychotic symptoms by sharing underlying alternations in cortical gray-matter volume (GMV) with the psychotic symptoms. Participants with schizophrenia ( N = 34) and their matched healthy controls ( N = 29) were tested for TSR against a two-talker-speech masker...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30017778/speech-structure-links-the-neural-and-socio-behavioural-correlates-of-psychotic-disorders
#18
Lena Palaniyappan, Natália Bezerra Mota, Shamuz Oowise, Vijender Balain, Mauro Copelli, Sidarta Ribeiro, Peter F Liddle
BACKGROUND: A longstanding notion in the concept of psychosis is the prominence of loosened associative links in thought processes. Assessment of such subtle aspects of thought disorders has proved to be a challenging task in clinical practice and to date no surrogate markers exist that can reliably track the physiological effects of treatments that could reduce thought disorders. Recently, automated speech graph analysis has emerged as a promising means to reliably quantify structural speech disorganization...
January 10, 2019: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://read.qxmd.com/read/29928594/speech-on-speech-masking-and-psychotic-symptoms-in-schizophrenia
#19
Chao Wu, Chuanyue Wang, Liang Li
People with schizophrenia have impairments of target-speech recognition (TSR) in noisy environments with multiple people talking. This study investigated whether the TSR impairment in schizophrenia is associated with their impaired auditory working memory or certain psychotic symptoms. Thirty participants with schizophrenia (mean age = 35.2 ± 12.7 years) and 30 demographics-matched healthy controls (mean age = 32.9 ± 10.9 years) were tested for their TSR against a two-talker-speech masker...
June 2018: Schizophrenia Research. Cognition
https://read.qxmd.com/read/29703662/dysregulation-of-auditory-neuroplasticity-in-schizophrenia
#20
Patrice Voss, Maryse E Thomas, Gerson D Guercio, Etienne de Villers-Sidani
Schizophrenia is a complex brain syndrome characterized by an array of positive symptoms (delusions, hallucinations, disorganized speech), negative symptoms (alogia, apathy, avolition) and cognitive impairments (memory, executive functions). Although investigations of the cognitive deficits in schizophrenia have primarily concentrated on disturbances affecting higher-order cognitive processes, there is an increasing realization that schizophrenia also affects early sensory processing, which might, in fact, play a significant role in the development of higher-order cognitive impairments...
April 24, 2018: Schizophrenia Research
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