keyword
https://read.qxmd.com/read/32351413/identifying-predictors-of-suicide-in-severe-mental-illness-a-feasibility-study-of-a-clinical-prediction-rule-oxford-mental-illness-and-suicide-tool-or-oxmis
#21
JOURNAL ARTICLE
Morwenna Senior, Matthias Burghart, Rongqin Yu, Andrey Kormilitzin, Qiang Liu, Nemanja Vaci, Alejo Nevado-Holgado, Smita Pandit, Jakov Zlodre, Seena Fazel
Background: Oxford Mental Illness and Suicide tool (OxMIS) is a brief, scalable, freely available, structured risk assessment tool to assess suicide risk in patients with severe mental illness (schizophrenia-spectrum disorders or bipolar disorder). OxMIS requires further external validation, but a lack of large-scale cohorts with relevant variables makes this challenging. Electronic health records provide possible data sources for external validation of risk prediction tools. However, they contain large amounts of information within free-text that is not readily extractable...
2020: Frontiers in Psychiatry
https://read.qxmd.com/read/31370036/treatment-emergent-violence-to-self-and-others-a-literature-review-of-neuropsychiatric-adverse-reactions-for-antidepressant-and-neuroleptic-psychiatric-drugs-and-general-medications
#22
REVIEW
Catherine Clarke, Jan Evans, Kelly Brogan
OBJECTIVE: This paper reviews the literature linking physical violence, directed towards self or others, to serotonergic and dopaminergic psychiatric drugs and general medications. DESIGN/METHODOLOGY/APPROACH: Data about side effects, pharmacogenetics and homeostasis are obtained from articles, electronic Medicines Compendium, DSM-IV-TR, British National Formulary (BNF) and academic books. Statistics have been obtained from articles, The National Confidential Inquiry into Suicide and Homicide by People with Mental Illness, Centre for Mental Health and Risk, Manchester, Mental Health Equalities, National Mental Health Development Unit and the NHS Health and Social Care Information Centre...
January 2019: Advances in Mind-body Medicine
https://read.qxmd.com/read/31276867/lithium-bioaccumulation-in-lentinus-crinitus-mycelial-biomass-as-a-potential-functional-food
#23
JOURNAL ARTICLE
Maria Graciela Iecher Faria, Katielle Vieira Avelino, Juliana Silveira do Valle, Glacy Jaqueline da Silva, Affonso Celso Gonçalves, Douglas Cardoso Dragunski, Nelson Barros Colauto, Giani Andrea Linde
Lentinus crinitus is an important basidiomycete consumed by ethnic groups from the Amazon, commonly found in decomposing trees with high lignolytic and antioxidant activities. Lithium is a mood stabilizer, antiepileptic, antipsychotic, and antidepressant used in clinical practice. This study aimed to evaluate L. crinitus mycelial biomass bioaccumulated with lithium in liquid cultivation medium. The malt extract medium was added from zero to 100 mg L-1 lithium from two lithium sources (Li2 CO3 and LiCl)...
June 28, 2019: Chemosphere
https://read.qxmd.com/read/31065245/identifying-violent-behavior-using-the-oxford-mental-illness-and-violence-tool-in-a-psychiatric-ward-of-a-german-prison-hospital
#24
JOURNAL ARTICLE
Vincent Negatsch, Alexander Voulgaris, Peter Seidel, Robert Roehle, Annette Opitz-Welke
Background: Although there is evidence that individuals who suffer from severe mental disorders are at higher risk for aggressive behavior, only a minority eventually become violent. In 2017, Fazel et al. developed a risk calculator (Oxford Mental Illness and Violence tool, OxMIV) to identify the risk of violent crime in patients with mental disorders. For the first time, we tested the predictive validity of the OxMIV in the department of psychiatry at the prison hospital in Berlin, Germany, and presented findings from our internal validation...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30799960/depressive-symptoms-during-pregnancy-and-postpartum-in-women-and-use-of-antidepressant-treatment-a-longitudinal-cohort-study
#25
JOURNAL ARTICLE
Charlotta Sunnqvist, Karin Sjöström, Hafrún Finnbogadóttir
Objective: The aim of this study was to investigate whether women, who reported "symptoms of depression" during pregnancy and up to 1.5 years postpartum, who reported domestic violence or not, were treated with antidepressant medication. Patients and methods: A prospective longitudinal cohort study recruited primi- and multiparous women (n=1,939). The Edinburgh Postnatal Depression Scale (EPDS), the NorVold Abuse Questionnaire, and a questionnaire about medication during pregnancy were distributed and administered three times, during early pregnancy, late pregnancy, and the postpartum period...
2019: International Journal of Women's Health
https://read.qxmd.com/read/30717435/what-we-have-learned-from-the-methadone-maintenance-treatment-of-dual-disorder-heroin-use-disorder-patients
#26
JOURNAL ARTICLE
Angelo G I Maremmani, Matteo Pacini, Icro Maremmani
Mental Disorders and Heroin Use Disorder (HUD) often co-occur and constitute correlated risk factors that the authors believe are best considered from a unitary perspective. In this article we review and discuss data collected by the V.P. Dole Research Group in Dual Disorder (V.P. Dole DD-RG) patients according to the following six discussion points: (1) Treatment of personality disorders during Methadone Maintenance Treatment (MMT); (2) Treatment of Mood Disorders during MMT; (3) Treatment of Anxiety Disorders during MMT; (4) Treatment of Psychotic Disorders during MMT; (5) Treatment of violence during MMT; (6) Treatment of Alcohol Use Disorder (AUD) during MMT...
February 3, 2019: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/30651174/depression-in-pregnancy
#27
REVIEW
Jhon Freddy Martínez-Paredes, Nathalia Jácome-Pérez
INTRODUCTION: Depression is the most common psychiatric morbidity in pregnancy, affecting more than 13% of pregnant women. Its diagnosis is based on the criteria established by the DSM-5 and the application of validated scales such as the Edinburgh Postnatal Depression Scale. However, there are still errors and shortcomings among healthcare professionals in the recognition, diagnosis and treatment of depression during pregnancy, with the resulting consequences and repercussions on the gestation itself or the foetus...
January 2019: Revista Colombiana de Psiquiatría
https://read.qxmd.com/read/30611959/psychiatric-and-psychological-follow-up-of-undergraduate-and-postgraduate-medical-students-prevalence-and-associated-factors-results-from-the-national-bourbon-study
#28
JOURNAL ARTICLE
G Fond, A Bourbon, C Lançon, M Boucekine, J-A Micoulaud-Franchi, P Auquier, L Boyer
BACKGROUND: Physicians are at risk of burnout, anxiety and depression. Prevention is needed from the beginning of the medical studies to detect early poor mental health outcomes. OBJECTIVE: To determine the prevalence and associated of psychiatric or psychological follow-up in a national sample of undergraduate and postgraduate medical students (UPMS). METHODS: UPMS of the 35 French Medicine faculties were recruited through mailing lists and social networks between December 2016 and May 2017 and fulfilled Internet anonymised questionnaires...
February 2019: Psychiatry Research
https://read.qxmd.com/read/30423419/illness-and-drug-modifiable-factors-associated-with-violent-behavior-in-homeless-people-with-severe-mental-illness-results-from-the-french-housing-first-fhf-program
#29
JOURNAL ARTICLE
G Fond, L Boyer, M Boucekine, V Girard, S Loubière, C Lenoir, P Auquier, A Tinland
OBJECTIVE: The aim of this study was to investigate the factors associated with violent behavior in a large multicenter sample of Homeless Schizophrenia (SZ) and Bipolar Disorder (BD) (HSB) subjects. METHODS: This multicenter study was conducted in 4 French cities: Lille, Marseille, Paris and Toulouse. Violent behavior was defined by at least one episode of verbal or physical violence in the last 6 months. RESULTS: Overall, 675 HSB patients, mean aged 38 years and 82...
November 10, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://read.qxmd.com/read/30050444/what-acute-stress-protocols-can-tell-us-about-ptsd-and-stress-related-neuropsychiatric-disorders
#30
REVIEW
Laura Musazzi, Paolo Tornese, Nathalie Sala, Maurizio Popoli
Posttraumatic stress disorder (PTSD), the fifth most prevalent mental disorder in the United States, is a chronic, debilitating mental illness with as yet limited options for treatment. Hallmark symptoms of PTSD include intrusive memory of trauma, avoidance of reminders of the event, hyperarousal and hypervigilance, emotional numbing, and anhedonia. PTSD is often triggered by exposure to a single traumatic experience, such as a traffic accident, a natural catastrophe, or an episode of violence. This suggests that stressful events have a primary role in the pathogenesis of the disorder, although genetic background and previous life events are likely involved...
2018: Frontiers in Pharmacology
https://read.qxmd.com/read/30005328/venus-and-mars-on-the-benches-of-the-faculty-influence-of-gender-on-mental-health-and-behavior-of-medical-students-results-from-the-bourbon-national-study
#31
JOURNAL ARTICLE
G Fond, A Bourbon, P Auquier, J-A Micoulaud-Franchi, C Lançon, L Boyer
Medical student wellness has emerged as an important issue in medical education. OBJECTIVE: To evaluate the gender influence on psychiatric and/or psychological follow-up, psychotropic and illicit drug consumption, addictive behaviors, quality of life and motives for consumption in a large multicentric national sample of medical students. METHODS: Medical students of the 35 French Medicine faculties were recruited through mailing lists and social networks between December 2016 and May 2017 and fulfilled Internet anonymized questionnaires...
October 15, 2018: Journal of Affective Disorders
https://read.qxmd.com/read/29936392/psychiatry-a-discipline-at-specific-risk-of-mental-health-issues-and-addictive-behavior-results-from-the-national-bourbon-study
#32
JOURNAL ARTICLE
G Fond, A Bourbon, J-A Micoulaud-Franchi, P Auquier, L Boyer, C Lançon
BACKGROUND: Physicians are at risk for burnout, anxiety and depression. OBJECTIVE: To explore the self-reported mental health status, substance use behavior and motives of a national sample of interns in psychiatry compared to other specialties. METHODS: Interns of the 35 French Medicine faculties were recruited through mailing lists and social networks between December 2016 and May 2018 and fulfilled internet anonymized questionnaires. RESULTS: Overall, 2165 interns (302 interns in psychiatry and 1863 in other specialties) mean aged 25...
October 1, 2018: Journal of Affective Disorders
https://read.qxmd.com/read/29206769/severe-menopausal-symptoms-associated-with-reduced-adherence-to-antiretroviral-therapy-among-perimenopausal-and-menopausal-women-living-with-hiv-in-metro-vancouver
#33
JOURNAL ARTICLE
Putu K Duff, Deborah M Money, Gina S Ogilvie, Florence Ranville, Mary Kestler, Melissa C Braschel, Neora Pick, Kate Shannon
OBJECTIVES: Although more women living with HIV (WLWH) are entering midlife, the experiences of perimenopausal and menopausal WLWH, including the effects of menopausal symptoms severity, remain understudied. This study longitudinally investigated the correlates of antiretroviral therapy (ART) adherence among perimenopausal and menopausal WLWH from Metro Vancouver. METHODS: Analyses drew on longitudinal data (2014-2017) from Sexual health and HIV/AIDS: Women's Longitudinal Needs Assessment, an ongoing community-based cohort of WLWH, aged 14+, from Metro Vancouver, Canada...
May 2018: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/28916143/violent-behavior-by-emergency-department-patients-with-an-involuntary-hold-status
#34
JOURNAL ARTICLE
Nancy L Dawson, Christian Lachner, Tyler F Vadeboncoeur, Michael J Maniaci, Veronica Bosworth, Teresa A Rummans, Archana Roy, M Caroline Burton
BACKGROUND: Violence against health care workers has been increasing. Health care workers in emergency departments (EDs) are highly vulnerable because they provide care for patients who may have mental illness, behavioral problems, or substance use disorders (alone or in combination) and who are often evaluated during an involuntary hold. Our objective was to identify factors that may be associated with violent behavior in ED patients during involuntary holds. METHODS: Retrospective review of patients evaluated during an involuntary hold at a suburban acute care hospital ED from January 2014 through November 2015...
March 2018: American Journal of Emergency Medicine
https://read.qxmd.com/read/28246265/considering-benefits-and-harms-of-duloxetine-for-treatment-of-stress-urinary-incontinence-a-meta-analysis-of-clinical-study-reports
#35
JOURNAL ARTICLE
Emma Maund, Louise Schow Guski, Peter C Gøtzsche
BACKGROUND: The European Medicines Agency makes clinical study reports publicly available and publishes reasons for not approving applications for marketing authorization. Duloxetine has been approved in Europe for the treatment of stress urinary incontinence in women. The reported adverse effects of duloxetine include mental health problems and suicidality. We obtained clinical study reports from the European Medicines Agency concerning use of this drug for stress urinary incontinence...
February 6, 2017: Canadian Medical Association Journal: CMAJ
https://read.qxmd.com/read/28081556/stressful-events-and-circumstances-reported-by-patients-prior-to-being-prescribed-antidepressants
#36
JOURNAL ARTICLE
Morgyn Hartdegen, Kerry Gibson, Claire Cartwright, John Read
AIMS: This study investigates the extent to which those who receive a prescription for antidepressants perceive psychosocial stressors to be significant in their difficulties. METHODS: This study draws on a survey of adults prescribed antidepressants. It analyses 1,683 responses to an open-ended question that enquired about difficult events and circumstances participants experienced in the time leading up to receiving an antidepressant prescription. RESULTS: Sixty-five percent of respondents described experiencing one or more stressful events or circumstances, with 19 % reporting two and 20% reporting three or more...
January 13, 2017: New Zealand Medical Journal
https://read.qxmd.com/read/27822978/history-of-violence-and-subjective-health-of-mother-and-child
#37
JOURNAL ARTICLE
Margret O Tomasdottir, Hildur Kristjansdottir, Amalia Bjornsdottir, Linn Getz, Thora Steingrimsdottir, Olof A Olafsdottir, Johann A Sigurdsson
OBJECTIVE: To study the self-reported prevalence of experienced violence among a cohort of women about two years after giving birth, their health during pregnancy, pregnancy outcomes and their experience of their child's health. SETTING AND SUBJECTS: In 2011, a total of 657 women participated in phase III of the Childbirth and Health Cohort Study in Icelandic Primary Health Care, 18 to 24 months after delivery. The women had previously participated in phase I around pregnancy week 16 and phase II 5-6 months after delivery...
December 2016: Scandinavian Journal of Primary Health Care
https://read.qxmd.com/read/27729596/precursors-to-suicidality-and-violence-on-antidepressants-systematic-review-of-trials-in-adult-healthy-volunteers
#38
REVIEW
Andreas Ø Bielefeldt, Pia B Danborg, Peter C Gøtzsche
OBJECTIVE: To quantify the risk of suicidality and violence when selective serotonin and serotonin-norepinephrine reuptake inhibitors are given to adult healthy volunteers with no signs of a mental disorder. DESIGN: Systematic review and meta-analysis. MAIN OUTCOME MEASURE: Harms related to suicidality, hostility, activation events, psychotic events and mood disturbances. SETTING: Published trials identified by searching PubMed and Embase and clinical study reports obtained from the European and UK drug regulators...
October 2016: Journal of the Royal Society of Medicine
https://read.qxmd.com/read/27354489/antidepressant-use-and-violent-crimes-among-young-people-a-longitudinal-examination-of-the-finnish-1987-birth-cohort
#39
JOURNAL ARTICLE
Elina Hemminki, Marko Merikukka, Mika Gissler, Kristian Wahlbeck, Jukka Savolainen, Tiina Ristikari, Mikko Aaltonen
BACKGROUND: The use of antidepressants, especially selective serotonin reuptake inhibitors (SSRIs), has been questioned due to poor efficacy and safety. We examined whether young violent offenders were more likely antidepressant users prior to their first violent offence than other young persons. METHODS: The study is a follow-up of children born in Finland in 1987 (n=59 120), linking national registers to each other using personal identity codes. Data on psychotropic drug use came from a register of reimbursed drugs and data on crimes from a register on court convictions (after the age of 14 years)...
January 2017: Journal of Epidemiology and Community Health
https://read.qxmd.com/read/27344405/chronic-pain-and-mental-health-disorders-shared-neural-mechanisms-epidemiology-and-treatment
#40
REVIEW
W Michael Hooten
Chronic pain and mental health disorders are common in the general population, and epidemiological studies suggest that a bidirectional relationship exists between these 2 conditions. The observations from functional imaging studies suggest that this bidirectional relationship is due in part to shared neural mechanisms. In addition to depression, anxiety, and substance use disorders, individuals with chronic pain are at risk of other mental health problems including suicide and cigarette smoking and many have sustained sexual violence...
July 2016: Mayo Clinic Proceedings
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