Shumpei Mizuta, Makoto Iwasaki, Noriko Bandai, Saya Yoshida, Asami Watanabe, Hiroshi Takashima, Takeshi Ueshimo, Kazuhiro Bandai, Kensuke Fujiwara, Naoko Hiranuma, Yusuke Koba, Takahito Kawata, Akira Tamekane, Mitsumasa Watanabe
INTRODUCTION: The CD34+ CD38- population in bone marrow includes hematopoietic stem/progenitor cells. Recently, in acute myeloid leukemia, the focus has shifted to flow cytometry analysis targeting CD34+ CD38- leukemic cells due to their effectiveness in minimal/measurable residual disease detection and prognosis prediction. Nevertheless, the immunophenotype and cell frequency of these cells in the bone marrow, in the absence of leukemic cells, remains unknown. We aimed to evaluate detailed characteristics of CD34+ CD38- cells in both normal and leukemic cells by flow cytometry...
November 6, 2023: Cytometry. Part B, Clinical Cytometry