Tom Burke, Laurena Holleran, David Mothersill, James Lyons, Nathan O'Rourke, Christina Gleeson, Dara M Cannon, Declan P McKernan, Derek W Morris, John P Kelly, Brian Hallahan, Colm McDonald, Gary Donohoe
OBJECTIVE: The Corona Radiata (CR) is a large white matter tract in the brain comprising of the anterior CR (aCR), superior CR (sCR), and posterior CR (pCR), which have associations with cognition, self-regulation, and, in schizophrenia, positive symptom severity. This study tested the hypothesis that the microstructural organisation of the aCR, as measured by Fractional Anisotropy (FA) using Diffusion Tensor Imaging (DTI), would relate to poorer social cognitive outcomes and higher positive symptom severity for people with schizophrenia, when compared to healthy participants...
November 4, 2023: Schizophrenia Research