Read by QxMD icon Read


Isabelle Pagé, Michael Swain, Arnold Wong, Alexander Breen, Diana De Carvalho, Martin Descarreaux, Martha Funabashi, Gregory Kawchuk
OBJECTIVE: The purpose of this study was to describe the correlations between individual characteristics and spinal stiffness as measured with different spinal stiffness measurement devices in individuals with and without back pain. METHODS: A secondary analysis of 3 adult data sets obtained using 3 different devices, in 2 spinal regions, from a total of 5 separate cross-sectional studies was conducted. Differences in spinal stiffness between men and women and in the strength of correlations among spinal stiffness and age and anthropometric characteristics were evaluated using either the t test for independent samples, Pearson's correlation coefficient, or Kendall's τ rank correlation coefficient...
November 2018: Journal of Manipulative and Physiological Therapeutics
Jacob Aaskov, Gregory N Kawchuk, Kenton D Hamaluik, Pierre Boulanger, Jan Hartvigsen
Objective: Since the discovery of ionizing radiation, clinicians have evaluated X-ray images separately from the patient. The objective of this study was to investigate the accuracy and repeatability of a new technology which seeks to resolve this historic limitation by projecting anatomically correct X-ray images on to a person's skin. Methods: A total of 13 participants enrolled in the study, each having a pre-existing anteroposterior lumbar X-ray. Each participant's image was uploaded into the Hololens Mixed reality system which when worn, allowed a single examiner to view a participant's own X-ray superimposed on the participant's back...
2019: PeerJ
Martha Funabashi, Katherine A Pohlman, Silvano Mior, Maeve O'Beirne, Michael Westaway, Diana De Carvalho, Mohamed El-Bayoumi, Bob Haig, Darrell J Wade, Haymo W Thiel, J David Cassidy, Eric Hurwitz, Gregory N Kawchuk, Sunita Vohra
Objectives: To: 1) develop/adapt and validate an instrument to measure patient safety attitudes and opinions of community-based spinal manipulative therapy (SMT) providers; 2) implement the instrument; and 3) compare results among healthcare professions. Methods: A review of the literature and content validation were used for the survey development. Community-based chiropractors and physiotherapists in 4 Canadian provinces were invited. Results: The Agency for Healthcare Research and Quality's (AHRQ) Medical Office Survey on Patient Safety Culture was the preferred instrument...
December 2018: Journal of the Canadian Chiropractic Association
Greg Kawchuk, Christine Goertz, Iben Axén, Martin Descarreaux, Simon French, Mitchell Haas, Jan Hartvigsen, Carolina Kolberg, Hazel Jenkins, Cynthia Peterson, John Taylor
No abstract text is available yet for this article.
October 2018: Dose-response: a Publication of International Hormesis Society
Paul A Oakley, Jerry M Cuttler, Deed E Harrison
No abstract text is available yet for this article.
October 2018: Dose-response: a Publication of International Hormesis Society
Arnold Y L Wong, Eric C Parent, Sukhvinder S Dhillon, Narasimha Prasad, Dino Samartzis, Gregory N Kawchuk
PURPOSE: Our prior study revealed that people with non-specific low back pain (LBP) who self-reported a > 30% improvement in disability after SMT demonstrated significant post-treatment improvements in spinal stiffness, dynamic muscle thickness and disc diffusion, while those not having self-reported improvement did not have these objective changes. The mechanism underlying this differential post-SMT response remains unknown. This exploratory secondary analysis aimed to determine whether persons with non-specific LBP who respond to spinal SMT have unique lumbar magnetic resonance imaging (MRI) findings compared to SMT non-responders...
February 2019: European Spine Journal
Ajay Matta, Muhammad Zia Karim, Hoda Gerami, Peter Jun, Martha Funabashi, Greg Kawchuk, Alyssa Goldstein, Warren Foltz, Marshall Sussman, Bjorn C Eek, W Mark Erwin
The tremendous cost, pain and disability associated with degenerative disc disease (DDD) makes the development of a biological agent that can mitigate the course of DDD, a critical unmet need. We have identified and reported that a single injection of a combination of recombinant human (rh) Transforming growth factor beta 1 (TGF-β1) and Connective tissue growth factor (CTGF) proteins into the injured intervertebral disc (IVD) nucleus pulposus (NP) can mediate DDD in a pre-clinical rodent model. In this study, we developed and evaluated the efficacy of a novel molecular therapy (NTG-101) containing rhTGF-β1 and rhCTGF proteins suspended in an excipient solution using in vivo models of DDD including rat-tail and chondrodystrophic (CD) canines...
November 14, 2018: Scientific Reports
Muhammad Alrwaily, Michael Timko, Michael Schneider, Greg Kawchuk, Christopher Bise, Karthik Hariharan, Joel Stevans, Anthony Delitto
We present the movement control approach as part of the treatment-based classification system. This approach proposes a movement control schema that clarifies that movement control is a product of the interplay among multiple biopsychosocial components. The schema illustrates that for movement to occur in a dynamically controlled fashion, the lumbar spine requires both local mobility and global stability. Local mobility means that the lumbar spine and its adjacent regions possess adequate nerve and joint(s) mobility and soft tissue compliance (ie, the malleability of tissue to undergo elastic deformation)...
December 1, 2017: Physical Therapy
Tarek Kaddoura, Anthony Au, Greg Kawchuk, Richard Uwiera, Richard Fox, Roger Zemp
Ultrafast ultrasound imaging is used to capture driven spinal vibrations as a new method for non-invasive spinal testing in living subjects. Previously, it has been shown that accelerometer-based vibration testing in cadaveric models can reveal the presence, location and magnitude of spinal pathology. However, this process remains an invasive procedure as current non-invasive sensors are inadequate. In this paper, the ability of non-invasive ultrafast ultrasound to quantify in vivo vertebral vibration response across a broad range of frequencies (10-100Hz) in anesthetized pig models is investigated...
June 25, 2018: Scientific Reports
Jaap H van Dieën, N Peter Reeves, Greg Kawchuk, Linda van Dillen, Paul W Hodges
Synopsis Motor control exercise has been shown to be effective in the management of low-back pain (LBP), but effect sizes are modest, possibly due to the fact that studies have used a one-size-fits-all approach, whereas literature suggests that patients may differ in presence or type of motor control issues. In this commentary, we address the question whether consideration of such variation in motor control issues might contribute to more personalized motor control exercise for patients with LBP. Such an approach is plausible, since motor control changes may play a role in persistence of pain through effects on tissue loading that may cause nociceptive afference in particular in case of peripheral sensitization...
June 12, 2018: Journal of Orthopaedic and Sports Physical Therapy
Jaap H van Dieën, N Peter Reeves, Greg Kawchuk, Linda van Dillen, Paul W Hodges
Synopsis Patients with low-back pain have been shown to display differences compared to healthy individuals in all aspects of trunk motor control, most often studied as differences in muscle activity and kinematics. However, differences in these aspects of motor control are largely inconsistent. We propose that this may reflect existence of two phenotypes, possibly the two ends of a distribution, one with "tight" control over trunk movement and one with "loose" control. Both may have beneficial effects, with tight control protecting against large tissue strains from uncontrolled movement and loose control protecting against high muscle forces and resulting spinal compression...
June 12, 2018: Journal of Orthopaedic and Sports Physical Therapy
Julie M Fritz, Jason A Sharpe, Elizabeth Lane, Doug Santillo, Tom Greene, Gregory Kawchuk
BACKGROUND: Low back pain is a common and costly condition. Spinal manipulative therapy (SMT) is a treatment supported in some guidelines, although most clinical trials examining SMT report small effect sizes. Enhancing the effects of SMT requires an understanding of underlying mechanisms and a systematic approach to leverage understanding of mechanisms to create more effective treatment protocols that are scalable in clinical practice. Prior work has identified effects on spinal stiffness and lumbar multifidus activation as possible mechanisms...
June 4, 2018: Trials
Katie E de Luca, Jordan A Gliedt, Matthew Fernandez, Greg Kawchuk, Michael S Swain
OBJECTIVE: To evaluate Australian and New Zealand chiropractic students' opinions regarding the identity, role setting, and future of chiropractic practice. METHODS: An online, cross-sectional survey was administered to chiropractic students in all chiropractic programs in Australia and New Zealand. The survey explored student viewpoints about the identity, role/scope, setting, and future of chiropractic practice as it relates to chiropractic education and health promotion...
October 2018: Journal of Chiropractic Education
Gregory Neil Kawchuk
The McAndrews Leadership Lecture was developed by the American Chiropractic Association to honor the legacy of Jerome F. McAndrews, DC, and George P. McAndrews, JD, and their contributions to the chiropractic profession. This article is an edited and truncated version of the McAndrews Leadership Lecture given by Dr Greg Kawchuk on February 27, 2016, in Washington, DC, at the National Chiropractic Leadership Conference. This was the second McAndrews lecture in this annual series.
December 2017: Journal of Chiropractic Humanities
Jon Adams, Greg Kawchuk, Alexander Breen, Diana De Carvalho, Andreas Eklund, Matthew Fernandez, Martha Funabashi, Michelle M Holmes, Melker S Johansson, Katie de Luca, Craig Moore, Isabelle Pagé, Katherine A Pohlman, Michael S Swain, Arnold Y L Wong, Jan Hartvigsen
In an evidence-based health care environment, healthcare professions require a sustainable research culture to remain relevant. At present however, there is not a mature research culture across the chiropractic profession largely due to deficiencies in research capacity and leadership, which may be caused by a lack of chiropractic teaching programs in major universities. As a response to this challenge the Chiropractic Academy for Research Leadership, CARL, was created with the aim of develop a global network of successful early-career chiropractic researchers under the mentorship of three successful senior academics from Australia, Canada, and Denmark...
2018: Chiropractic & Manual Therapies
Simon D French, Ronda Parkes, Paul Bruno, Steven Passmore, Jill A Hayden, John Srbely, Greg Kawchuk
Our research group recently published a Delphi study that identified Canadian chiropractic profession research priority areas. At the same time, the Canadian Chiropractic Research Foundation (CCRF) was developing their own research priority areas. In this commentary, we discuss the results of the Delphi study, compare and contrast these results to the research priorities of the CCRF, and report new data from a survey about where members of the chiropractic profession think that available research funding should be spent...
December 2017: Journal of the Canadian Chiropractic Association
Kent Stuber, Greg Kawchuk, Andre Bussières
Objective: To better understand the research resources and environment within the Canadian chiropractic profession. Methods: All members of the Canadian Chiropractic Association (n=7200) were invited to access an electronic survey on research capacity, activity, and resources. Canadian chiropractic stakeholder organizations received an invitation to participate in a related survey. Results: 505 CCA members completed the survey (7.0% completed response rate, 65% males, 19% with graduate degrees)...
December 2017: Journal of the Canadian Chiropractic Association
Martha Funabashi, François Nougarou, Martin Descarreaux, Narasimha Prasad, Gregory N Kawchuk
BACKGROUND CONTEXT: Previous studies found that the intervertebral disc (IVD) experiences the greatest loads during spinal manipulation therapy (SMT). PURPOSE: Based on that, this study aimed to determine if loads experienced by spinal tissues are significantly altered when the application site of SMT is changed. STUDY DESIGN: A biomechanical robotic serial dissection study. SAMPLE: Thirteen porcine cadaveric motion segments...
June 2018: Spine Journal: Official Journal of the North American Spine Society
G S Luka, E Nowak, J Kawchuk, M Hoorfar, H Najjaran
In this work, a low-cost, portable device is developed to detect colorimetric assays for in-field and point-of-care (POC) analysis. The device can rapidly detect both pH values and nitrite concentrations of five different samples, simultaneously. After mixing samples with specific reagents, a high-resolution digital camera collects a picture of the sample, and a single-board computer processes the image in real time to identify the hue-saturation-value coordinates of the image. An internal light source reduces the effect of any ambient light so the device can accurately determine the corresponding pH values or nitrite concentrations...
November 2017: Royal Society Open Science
Adriana F Fusaro, Deborah A Barton, Kenlee Nakasugi, Craig Jackson, Melanie L Kalischuk, Lawrence M Kawchuk, Maite F S Vaslin, Regis L Correa, Peter M Waterhouse
The plant viral family Luteoviridae is divided into three genera: Luteovirus , Polerovirus and Enamovirus . Without assistance from another virus, members of the family are confined to the cells of the host plant's vascular system. The first open reading frame (ORF) of poleroviruses and enamoviruses encodes P0 proteins which act as silencing suppressor proteins (VSRs) against the plant's viral defense-mediating RNA silencing machinery. Luteoviruses, such as barley yellow dwarf virus-PAV (BYDV-PAV), however, have no P0 to carry out the VSR role, so we investigated whether other proteins or RNAs encoded by BYDV-PAV confer protection against the plant's silencing machinery...
October 10, 2017: Viruses
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"