keyword
https://read.qxmd.com/read/37954100/effectiveness-of-the-treatment-of-depression-associated-with-cancer-and-neuroimaging-changes-in-depression-related-brain-regions-in-patients-treated-with-the-mediator-deuterium-acupuncture-method
#21
JOURNAL ARTICLE
Jianlun Lian, Weiyuan Sun, Fang Dong, Xueliang Zhu, Xue Sun, Songtao Jia, Limin Gao, Meimei Wei
Cancer patients should be concerned about depression, which can negatively impact their mental health. To develop efficient therapies, it is essential to comprehend the connection between cancer and depression. This study used neuroimaging to investigate the use of mediator-deuterium acupuncture (MDA) for people with cancer-induced depression and its effects on brain regions associated with depression. Resting-state functional magnetic resonance imaging and neurocognitive testing were conducted on the participants, and statistical package for the social sciences was utilized to analyze the behavioral data...
2023: Open Life Sciences
https://read.qxmd.com/read/37946117/identifying-trajectories-and-predictors-of-chemotherapy-induced-peripheral-neuropathy-symptoms-physical-functioning-and-falls-across-treatment-and-recovery-in-adults-treated-with-neurotoxic-chemotherapy-the-pattern-observational-study-protocol-nct05790538
#22
JOURNAL ARTICLE
Kerri M Winters-Stone, Stephanie M Krasnow, Fay B Horak, Martina Mancini, Michelle H Cameron, Nathan F Dieckmann, Sydnee A Stoyles, Eric J Roeland
BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and dose-limiting side effect of systemic cancer therapy. In many cancer survivors, CIPN persists after treatment ends and is associated with functional impairments, abnormal gait patterns, falls, and diminished quality of life. However, little is known regarding which patients are most likely to develop CIPN symptoms that impair mobility and increase fall risk, when this risk develops, or the optimal timing of early intervention efforts to mitigate the impact of CIPN on functioning and fall risk...
November 10, 2023: BMC Cancer
https://read.qxmd.com/read/37922279/effects-of-music-intervention-combined-with-progressive-muscle-relaxation-on-anxiety-depression-stress-and-quality-of-life-among-women-with-cancer-receiving-chemotherapy-a-pilot-randomized-controlled-trial
#23
JOURNAL ARTICLE
Khanh Thi Nguyen, Huong T X Hoang, Quang V Bui, Dorothy N S Chan, Kai C Choi, Carmen W H Chan
UNLABELLED: Beneficial effects of music intervention and progressive muscle relaxation alone on psychological issues were reported, however, studies evaluating their combined effects are limited. This study aimed to investigate the feasibility, acceptability and preliminary effects of music intervention combined with progressive muscle relaxation on anxiety, depression, stress, and quality of life among breast and gynaecological cancer patients receiving chemotherapy. METHODS: The study was carried out from March to May 2022 in an oncology hospital in Vietnam...
2023: PloS One
https://read.qxmd.com/read/37899067/establishment-and-evaluation-of-the-impact-of-a-supervisory-group-for-chemotherapy-safety-management-in-an-oncology-department
#24
JOURNAL ARTICLE
Li-Hua Deng, Ting-Ting Yao, Hai-Yan Jin, Yi Li, Yi Zong, Mei-Gui Chen, Peng Chen
BACKGROUND: The nursing model of establishing a chemotherapy safety management supervisory group has guaranteed the safety and effectiveness of intravenous chemotherapy while reducing the adverse effects of chemotherapy and improving patient satisfaction and quality of life. OBJECTIVE: To explore the impact of establishing a nursing supervision group on improving the safety management of patients receiving chemotherapy in the oncology department. METHODS: We selected a total of 60 patients who underwent chemotherapy at the oncology department between January and June 2021 and assigned them to the control group...
October 19, 2023: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://read.qxmd.com/read/37868157/compas-y-a-mixed-methods-pilot-evaluation-of-a-mobile-self-compassion-training-for-people-with-newly-diagnosed-cancer
#25
JOURNAL ARTICLE
Judith Austin, Maya J Schroevers, Jelle Van Dijk, Robbert Sanderman, Elin Børøsund, A Machteld N Wymenga, Ernst T Bohlmeijer, Constance H C Drossaert
OBJECTIVE: Compas-Y is a compassionate mind training app that was co-designed to be fully adapted to mobile technology and to people with newly diagnosed cancer. This study aimed to evaluate the use, appreciation and impact of the app. METHODS: Seventy-one people with cancer who created an app account were included (38% breast cancer, 72% diagnosed <4 months ago, 76% received chemotherapy). Participants had very high baseline scores of self-compassion. In a convergent mixed methods design, back-end log-data ( n  = 71), pre-post surveys ( n  = 34) and semi-structured interviews ( n  = 23) collected for >8 weeks and were concurrently analysed using joint displays...
2023: Digital Health
https://read.qxmd.com/read/37835144/depressed-mood-as-a-significant-risk-factor-for-gynecological-cancer-aggravation
#26
JOURNAL ARTICLE
Seon-Mi Lee, Jae-Yun Song, Aeran Seol, Sanghoon Lee, Hyun-Woong Cho, Kyung-Jin Min, Jin-Hwa Hong, Jae-Kwan Lee, Nak-Woo Lee
BACKGROUND: The aim of this study was to evaluate the relationship between depressed mood and gynecological cancer outcomes, identifying risk factors for cancer aggravation. METHODS: This study was a retrospective analysis of gynecological cancer patients (January 2020-August 2022) at Korea University Anam Hospital using Patient Health Questionnaire-9 (PHQ-9). Patients were classified into non-depressed mood (NDM)- and depressed mood (DM)-based scores. Statistical analysis was performed using Student's t -test, chi-square test, Fisher's exact test, Kaplan-Meier analysis, and Cox regression analyzing using SPSS...
October 2, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/37818511/atypical-presentation-of-acute-pericarditis-secondary-to-allogeneic-hematopoietic-stem-cell-transplantation-a-case-report
#27
Sourabh Goyal, Angela Khidhir, Matthew D Burwinkel
Cardiotoxicity linked with hematopoietic stem cell transplantation (HSCT) is a well-described phenomenon associated with an increased mortality risk; however, the majority of cardiac events present over 100 days following transfusion and are often attributed to graft-versus-host disease or pre-treatment conditioning by chemotherapy with or without radiation therapy. Here, we present the case of a 60-year-old female with a medical history of chronic lymphocytic leukemia complicated by a myelodysplastic syndrome that progressed to acute myeloid leukemia who developed chest pain immediately following an allogeneic HSCT...
September 2023: Curēus
https://read.qxmd.com/read/37801182/do-cancer-curvivors-and-metavivors-have-distinct-needs-for-stress-management-intervention-retrospective-analysis-of-a-mind-body-survivorship-program
#28
JOURNAL ARTICLE
Lucy Finkelstein-Fox, Cayley C Bliss, Autumn W Rasmussen, Daniel L Hall, Areej El-Jawahri, Giselle K Perez, Lara N Traeger, Amy H Comander, Jeffrey Peppercorn, Reid Anctil, Elise Noonan, Elyse R Park
PURPOSE: Cancer "curvivors" (completed initial curative intent treatment with surgery, radiation, chemotherapy, and/or other novel therapies) and "metavivors" (living with metastatic or chronic, incurable cancer) experience unique stressors, but it remains unknown whether these differences impact benefits from mind-body interventions. This study explored differences between curvivors and metavivors in distress (depression, anxiety, worry) and resiliency changes over the course of an 8-week group program, based in mind-body stress reduction, cognitive-behavioral therapy (CBT), and positive psychology...
October 6, 2023: Supportive Care in Cancer
https://read.qxmd.com/read/37787271/pre-and-post-treatment-quality-of-life-among-patients-of-hepatobiliary-and-pancreatic-cancers-in-north-india-a-prospective-study
#29
JOURNAL ARTICLE
Ermeen Khurshied Wani, Shabab Lalit Angurana, Dinesh Kumar, Kiran Bala, Majid Jehangir, Shoket Chowdhary
CONTEXT: Studies reporting quality of life (QOL) measures alongside conventional measures of effectiveness of interventions and outcome are essential. AIMS: We aimed to compare QOL and mental well-being in hepatobiliary and pancreatic cancer patients before and after receiving treatment. SETTINGS AND DESIGN: This was a hospital-based prospective study. METHODS AND MATERIALS: The study was conducted in North India for a period of 1 year...
2023: Journal of Cancer Research and Therapeutics
https://read.qxmd.com/read/37785638/newly-diagnosed-mental-health-disorders-in-patients-with-breast-cancer-receiving-radiation-therapy
#30
JOURNAL ARTICLE
B Loving, M F Almahariq, R Levitin, S Ramanathan, L Qu, Z Ijaz, J T Dilworth
PURPOSE/OBJECTIVE(S): Patients with a mental health disorder (MHD) have higher age-adjusted mortality compared to the general population. There are few reports investigating the factors that contribute to newly diagnosed MHD following the diagnosis and treatment of breast cancer. Here, we report the incidence of acquired MHD after the diagnosis and treatment of breast cancer in patients who received radiation therapy. MATERIALS/METHODS: A database query of a single institution, prospectively maintained database identified patients diagnosed with breast cancer who received whole or partial breast irradiation (WB/PBI) or post-mastectomy radiotherapy (PMRT)...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37758656/toxic-leukoencephalopathy-versus-delayed-post-hypoxic-leukoencephalopathy-after-oral-morphine-sulphate-overdose
#31
JOURNAL ARTICLE
Nicholas P Rossi, Goutham Sathyanarayanan, MdSakir Mahmood, David Shakespeare
Toxic leukoencephalopathy (TLE) is a rare pathology caused by various substances including opioids (notably heroin), immunosuppressants, chemotherapy agents, cocaine, alcohol and carbon monoxide. However, although heroin is metabolised by the body into morphine, there is a striking paucity in cases of primary oral morphine-induced TLE, especially in the adult population. We present the case of a man in his 40s admitted to hospital in respiratory depression with a Glasgow Coma Scale (GCS) score of 6 after taking an overdose of oral morphine sulphate...
September 27, 2023: BMJ Case Reports
https://read.qxmd.com/read/37720456/the-effect-of-cognitive-behavioral-therapy-on-chemotherapy-induced-side-effects-and-immune-function-in-colorectal-cancer-patients-undergoing-chemotherapy-study-protocol-for-a-randomized-controlled-trial
#32
JOURNAL ARTICLE
Meijuan Wang, Yuanhong Xu, Jingqing Shi, Chengle Zhuang, Ying Zhuang, Jiyu Li, Peter H Cashin
BACKGROUND: Colorectal cancer (CRC) was one of the most widely diagnosed cancers in the United States in 2021. CRC patients may experience significant psychological stress and are susceptible to depression and anxiety. Previous studies have shown that cognitive behavioral therapy (CBT) can reduce fatigue and improve quality of life among breast cancer patients. However, as a non-pharmaceutical treatment, it remains unclear whether CBT improves chemotherapy-induced side effects and immune function in CRC patients...
August 31, 2023: Journal of Gastrointestinal Oncology
https://read.qxmd.com/read/37699115/melatonin-supplementation-for-cancer-related-fatigue-in-patients-with-early-stage-breast-cancer-receiving-radiotherapy-a-double-blind-placebo-controlled-trial
#33
RANDOMIZED CONTROLLED TRIAL
Nitai D Mukhopadhyay, Adam Khorasanchi, Sudeep Pandey, Srinidhi Nemani, Gwendolyn Parker, Xiaoyan Deng, Douglas W Arthur, Alfredo Urdaneta, Egidio Del Fabbro
BACKGROUND: Fatigue is common in patients undergoing radiotherapy (RT) and can significantly impact quality of life. Melatonin, a safe inexpensive natural supplement, may improve symptoms and attenuate the side effects of RT. The purpose of this randomized double-blind placebo-controlled phase III trial was to assess the effects of melatonin for preventing fatigue and other symptoms in patients with breast cancer undergoing RT. METHODS: Female early stage or Ductal carcinoma in situ patients with breast cancer ≥18 years of age with Eastern Cooperative Oncology Group (ECOG) performance status <3, hemoglobin ≥9 g/dL, planned for outpatient RT treatment with curative intent, were randomized 1:1 to melatonin 20 mg or placebo, orally, starting the night before RT initiation until 2 weeks post-RT...
February 2, 2024: Oncologist
https://read.qxmd.com/read/37677749/symptom-clusters-in-patients-with-colorectal-cancer-and-diabetes-over-time
#34
JOURNAL ARTICLE
Susan Storey, Xiao Luo, Jie Ren, Kun Huang, Diane Von Ah
OBJECTIVES: To examine symptoms and symptom clusters in patients with colorectal cancer (CRC) with or without diabetes at three key periods (0-6 months, 12-18 months, and 24-30 months) post-initial chemotherapy. SAMPLE &AMP; SETTING: Patients with CRC from a cancer center in the midwestern United States between January 2007 and December 2017. METHODS &AMP; VARIABLES: Eight of the most common symptoms (fatigue, gastrointestinal issues, depression, anxiety, peripheral neuropathy, physical function, cognition, and sleep disturbance) reported by patients with CRC and patients with diabetes were extracted from electronic health records...
June 15, 2023: Oncology Nursing Forum
https://read.qxmd.com/read/37674711/effects-of-chronotype-tailored-bright-light-intervention-on-symptoms-and-quality-of-life-in-breast-cancer-survivors
#35
Horng-Shiuann Wu, Feng Gao, Jean E Davis, Charles W Given
Purpose Bright light therapy holds promise for reducing common symptoms, e.g., fatigue, experienced by individuals with cancer. This study aimed to examine the effects of a chronotype-tailored bright light intervention on sleep disturbance, fatigue, depressive mood, cognitive dysfunction, and quality of life among post-treatment breast cancer survivors. Methods In this two-group randomized controlled trial (NCT03304587), participants were randomized to receive 30-min daily bright blue-green light (12,000 lux) or dim red light (5 lux) either between 19:00-20:00 h or within 30 min of waking in the morning...
August 25, 2023: Research Square
https://read.qxmd.com/read/37653829/pre-and-post-operative-comprehensive-nursing-care-versus-conventional-nursing-care-an-evaluation-of-quality-of-life-postoperative-pain-adverse-effects-and-treatment-satisfaction-of-patients-who-underwent-surgeries-and-interventional-therapies-for-liver-cancer
#36
JOURNAL ARTICLE
PeiPei Chen, LiQun Zhang, JinFeng Sun, QiaoYing Xing, Dan Shi
Interventional therapies including chemotherapies and radiotherapies are the most preferred treatment for liver cancer. However, these therapies have adverse effects. Therefore, careful care is required to relieve these adverse effects. The objectives of this study were to evaluate the quality of life, pain, anxiety, depression, adverse effects, and satisfaction of patients with liver cancer who received pre- and post-operative comprehensive nursing care against those of patients who received conventional nursing care...
August 25, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37637432/inflammation-related-proteins-as-biomarkers-of-treatment-related-behavioral-symptoms-a-longitudinal-study-of-breast-cancer-patients-and-age-matched-controls
#37
JOURNAL ARTICLE
Sunita K Patel, Elizabeth C Breen, I Benjamin Paz, Laura Kruper, Joanne Mortimer, F Lennie Wong, Smita Bhatia, Michael R Irwin, Carolyn E Behrendt
BACKGROUND: Behavioral symptoms in breast cancer (BC) survivors have been attributed to cancer treatment and resulting inflammation. However, studies linking behavioral symptoms to BC treatment have observed patients only after some treatment. Our prospective study with pre-treatment baseline investigates post-treatment changes in inflammation-related biomarkers and whether those changes correlate with changes in symptoms. METHODS: Participants were postmenopausal women, newly-diagnosed with stage 0-3 BC before any treatment (n = 173 "patients"), and age-matched women without cancer (n = 77 "controls"), who were assessed on plasma markers [soluble tumor necrosis factor receptor type 2 (sTNF-RII), interleukin (IL)-6, IL-1 receptor antagonist (IL-1RA), C-reactive protein (CRP)]) and symptoms (Physical Functioning, Pain, Attention/concentration, Perceived Cognitive Problems, Fatigue, Sleep Insufficiency, Depression)...
October 2023: Brain, behavior, & immunity health
https://read.qxmd.com/read/37598196/neo-train-study-protocol-and-feasibility-results-for-a-two-arm-randomized-controlled-trial-investigating-the-effect-of-supervised-exercise-during-neoadjuvant-chemotherapy-on-tumour-response-in-patients-with-breast-cancer
#38
JOURNAL ARTICLE
Eva Kjeldsted, Gunn Ammitzbøll, Lars Bo Jørgensen, Alexey Lodin, Rasmus Dahlin Bojesen, Silvia Gonzalez Ceballos, Susanne Rosthøj, Anne-Vibeke Lænkholm, Søren T Skou, Sandy Jack, Julie Gehl, Susanne Oksbjerg Dalton
BACKGROUND: Prehabilitation with exercise interventions during neoadjuvant chemotherapy (NACT) is effective in reducing physical and psychosocial chemotherapy-related adverse events in patients with cancer. In preclinical studies, data also support a growth inhibitory effect of aerobic exercise on the tumour microenvironment with possible improved chemotherapy delivery but evidence in human patients is limited. The aim of the study here described is to investigate if supervised exercise with high-intensity aerobic and resistance training during NACT can improve tumour reduction in patients with breast cancer...
August 19, 2023: BMC Cancer
https://read.qxmd.com/read/37551156/giving-information-strategically-and-transparently-a-pilot-trial-of-the-oncolo-gist-intervention-to-promote-patients-prognostic-understanding
#39
JOURNAL ARTICLE
Holly G Prigerson, David Russell, Sophia E Kakarala, Heather M Derry-Vick, Manish A Shah, Ashish Saxena, Valerie F Reyna, Allyson Ocean, Ronald Scheff, Paul K Maciejewski, Andrew S Epstein
PURPOSE: Most patients with cancer lack the prognostic understanding necessary to make informed decisions. We tested the feasibility and acceptability of the Oncolo-GIST ("Giving Information Strategically and Transparently, GIST") intervention and explored its associations with patients' improved prognostic understanding. METHODS: The Oncolo-GIST intervention distills prognostic discussions into easy-to-understand talking points. Patients with metastatic cancers that progressed on ≥1 line of chemotherapy and not expected to survive 12 months (n = 31) were recruited from October 2020 through November 2022...
August 8, 2023: Cancer Medicine
https://read.qxmd.com/read/37500312/higher-lifetime-stress-and-symptom-burden-contribute-to-the-occurrence-of-shortness-of-breath
#40
JOURNAL ARTICLE
Joosun Shin, Kord Kober, Patsy Yates, Melisa L Wong, Bruce A Cooper, Steven M Paul, Marilyn Hammer, Yvette Conley, Jon D Levine, Fay Wright, Christine Miaskowski
OBJECTIVES: Among four classes of patients with distinct shortness of breath profiles, evaluate for differences in levels of global, cancer-specific, and cumulative life stress, as well as resilience; evaluate for differences in the occurrence rates for various stressful life events, and evaluate for differences in the severity of common co-occurring symptoms. DATA SOURCES: Outpatients (N = 1338) completed questionnaires six times over two cycles of chemotherapy...
July 25, 2023: Seminars in Oncology Nursing
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