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post chemotherapy depression

V Walburg, M Rueter, S Lamy, G Compaci, M Lapeyre-Mestre, G Laurent, F Despas
The aim of this study was to measure the prevalence of FCR among a sample of French lymphoma survivors and to determine factors associated with clinical levels of FCR. The study was conducted with two cross-sectional measures: sociodemographic and anxiety, depression as well as health-related quality of life (HRQoL) scores were measured at the baseline of the post-cancer period and FCR was evaluated during the first 3 years of survivorship. The prevalence of clinical levels of FCR (≥13) was evaluated by the Fear of Cancer Recurrence Inventory - Short Form (FCRI-SF) among non- and Hodgkin lymphoma survivors undergoing prior first-line chemotherapy...
February 4, 2019: Psychology, Health & Medicine
Ashraf S Habib, Miklos D Kertai, Mary Cooter, Rachel A Greenup, Shelley Hwang
BACKGROUND AND OBJECTIVES: There are few prospective studies providing comprehensive assessment of risk factors for acute and persistent pain after breast surgery. This prospective observational study assessed patient-related, perioperative, and genetic risk factors for severe acute pain and persistent pain following breast cancer surgery. METHODS: Women presenting for elective breast cancer surgery completed State Trait Anxiety Inventory, Beck Depression Inventory, and Pain Catastrophizing Scale questionnaires preoperatively...
February 2019: Regional Anesthesia and Pain Medicine
Ryo Okubo, Hiroko Noguchi, Kei Hamazaki, Masayuki Sekiguchi, Takayuki Kinoshita, Noriko Katsumata, Tomomi Narisawa, Yasuhito Uezono, Jinzhong Xiao, Yutaka J Matsuoka
BACKGROUND: The pathophysiology of fear of cancer recurrence (FCR), the leading unmet psychological need of cancer survivors, may involve the dysfunctional processing of fear memory. n-3 polyunsaturated fatty acids (PUFAs) have beneficial effects on psychiatric disorders, including depressive disorder and anxiety disorders, and are involved in fear memory processing. We hypothesized that n-3 PUFA composition is associated with FCR in cancer survivors. METHODS: We conducted a cross-sectional study to examine the relationship between n-3 PUFAs and FCR among breast cancer survivors...
February 15, 2019: Journal of Affective Disorders
Margaret F Bedillion, Emily B Ansell, Gwendolyn A Thomas
OBJECTIVES: Breast cancer survivors report significant cognitive impairments post treatment, particularly following chemotherapy. Depression may also occur post treatment and may partially mediate the effects of cancer treatment on cognition. Additionally, physical activity has been shown to mitigate treatment effects on cognition and depression. This study examined the role of depression in mediating the effects of cancer treatment on cognitive function (perceived cognitive impairment, PCI; perceived cognitive ability, PCA) in breast cancer survivors and explored the role of physical activity in moderating these effects...
January 16, 2019: Breast: Official Journal of the European Society of Mastology
Marcie D Haydon, Annette L Stanton, Patricia A Ganz, Julienne E Bower
PURPOSE: Cancer-related goal disturbance can influence long-term outcomes in cancer patients and survivors; however, few studies have examined the factors that contribute to goal disturbance in early survivorship. DESIGN: The current study examined the relationships between demographic variables, cancer- and treatment-related factors, and behavioral and psychological symptoms (i.e., fatigue, pain, cognitive complaints, depressive symptoms, and anxiety) and goal disturbance in breast cancer survivors 1 year after treatment completion...
January 25, 2019: Journal of Psychosocial Oncology
Jing Lu, Zhaohui Zhang
To analyze the application of ear-acupuncture for post-operative syndromes of breast cancer so as to provide method and evidence for the syndromes. The related clinical literature was retrieved from CNKI, WANFANG and VIP databases from the database establishment time to August 30, 2017. We found ear-acupuncture are mainly used in treating nausea and vomiting caused by radiation and chemotherapy (shenmen (TF4 ), jiaogan (AH6a ), wei (CO4 ), pi (CO13 ), etc), insomnia in the rehabilitation period (xin (CO15 ), pizhixia (AT4 ), shenmen (TF4 ), etc), depression and anxiety (pizhixia (AT4 ), shenmen (TF4 ), pi (CO13 ), wei (CO4 ), xin (CO15 ), gan (CO12 ), etc), and joint pain (pain point), etc...
November 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Xiaomei Dong, Guangwei Sun, Jiaoyang Zhan, Fang Liu, Siping Ma, Penglei Li, Chan Zhang, Huijie Zhang, Chengzhong Xing, Ying Liu
BACKGROUND: Colorectal cancer patients undergoing postoperative chemotherapy often exhibit symptoms of depression that in turn may negatively affect outcome. The aim of this study was to assess the efficacy of telephone-based reminiscence therapy on the depression, anxiety, subjective well-being, and social support of colorectal cancer patients undergoing postoperative chemotherapy complicated with depression. METHODS: Patients were divided randomly into a control group (CON, n = 45), telephone support group (TS, n = 45), and telephone-based reminiscence therapy group (TBR, n = 45)...
December 4, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Ning Li, Yong-Wei Tian, Yue Xu, Dan-Dan Meng, Ling Gao, Wen-Jie Shen, Zong-Lan Liu, Zhi-Qiao Xu
To investigate the clinical efficacy of autologous cytokine induced killer (CIK) cells transfusion combined with radiochemotherapy in the treatment of advanced cervical cancer. A total of 89 hospitalized patients with advanced cervical cancer were admitted and divided into the treatment group (44 cases, autologous CIK cells transfusion combined with radiochemotherapy) and the control group (45 cases, radiochemotherapy) by a randomized non-blind method. Comparisons of therapeutic efficacies, immune functions, life qualities and survival rates were analyzed between the two groups...
December 3, 2018: Pathology Oncology Research: POR
R F M Vermeulen, M van Beurden, K N Gaarenstroom, T Teunis, J M Kieffer, N K Aaronson, G G Kenter, C M Korse
OBJECTIVES: The aim of this study was to investigate whether serum anti-Müllerian hormone (AMH) predicts symptom burden after risk-reducing salpingo-oophorectomy (RRSO) in order to individualize counseling. METHODS: Patient-reported menopausal symptoms, sexual functioning, and psychological distress (depression and anxiety) were assessed 1 day before (T0) and 6 weeks (T1) and 7 months (T2) after RRSO. AMH was assessed before RRSO. Multivariable regression analysis was used to investigate the association between AMH and short-term and long-term change in symptom burden following RRSO...
October 8, 2018: Climacteric: the Journal of the International Menopause Society
Eytan M Stein, Min Yang, Annie Guerin, Wei Gao, Philip Galebach, Cheryl Q Xiang, Subrata Bhattacharyya, Gaetano Bonifacio, George J Joseph
BACKGROUND: Preference valuations of health status are essential in health technology and economic appraisal. This study estimated utilities for treatment-related health states of acute myeloid leukemia (AML) and disutilities of severe adverse events (SAEs) using a representative sample of adults from the general population in the United States (US). METHODS: Treatment-related AML health states, defined based on literature and interviews with clinicians, included complete remission (CR), no CR, relapse, stem cell transplant (SCT), and post SCT short-term recovery...
September 21, 2018: Health and Quality of Life Outcomes
Cara L McDermott, Aasthaa Bansal, Scott D Ramsey, Gary H Lyman, Sean D Sullivan
CONTEXT: Limited data exist regarding how depression diagnosed at different times relative to a cancer diagnosis may affect healthcare utilization at end of life (EOL). OBJECTIVES: To assess the relationship between depression and health care utilization at EOL among older adults (ages >=67) diagnosed with advanced non-small cell lung cancer (NSCLC) from 2009 to 2011. METHODS: Using the SEER-Medicare database, we fit multivariable logistic regression models to explore the association of depression with duration of hospice stay plus high-intensity care, for example inpatient admissions, in-hospital death, emergency department visits, and chemotherapy at EOL...
November 2018: Journal of Pain and Symptom Management
Jessica L Krok-Schoen, Katia Fernandez, Gary W Unzeitig, Griselda Rubio, Electra D Paskett, Douglas M Post
OBJECTIVE: Patient-clinician communication difficulties are a major barrier to effective symptom management during chemotherapy especially among non-English-speaking and minority patients. This study sought to examine how information is exchanged between patients and clinicians during chemotherapy treatment regarding pain, depression, fatigue, and nausea experienced among the most prevalent non-English-speaking group in the USA, Hispanic breast cancer survivors. METHODS: Hispanic breast cancer patients and clinicians participated in focus groups to examine Hispanic breast cancer survivors' experience and patient-physician communication of symptoms during chemotherapy...
July 30, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Jean-Lionel Bagot, Natalia Marechaud, Nicolas Deana, Julie Wendling
BACKGROUND:  During chemotherapy, the correlation between insomnia and fatigue, anxiety, pain, depressed mood, and cognitive disorders makes these subjective complaints a 'symptom cluster' with common biological mechanisms. The theory of cerebral inflammation following the production of pro-inflammatory cytokines (high level of interleukin 1-β [IL1-β], IL6 and tumour necrosis factor-alpha) is currently the most generally accepted. Understanding these mechanisms should allow us to propose a chemoprotective homeopathic treatment of the nervous system...
November 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Eran Ben-Arye, Hadeel Dahly, Yael Keshet, Jamal Dagash, Noah Samuels
CONTEXT AND OBJECTIVES: To examine the impact of a complementary/integrative medicine (CIM) program on quality of life (QoL)-related concerns among patients scheduled for chemotherapy for breast and gynecologic cancer. METHODS: Chemotherapy-naïve patients were referred by their oncology healthcare professional to an integrative oncology program, where CIM is provided as part of palliative/supportive care. CIM treatments were tailored to patients' preferences and leading concerns, and for most included acupuncture and mind-body-spirit modalities, which were usually co-administered in the week preceding the first chemotherapy cycle...
September 2018: Journal of Cancer Research and Clinical Oncology
Estherina Trachtenberg, Tatiana Mashiach, Rachel Ben Hayun, Tamar Tadmor, Tali Fisher, Judith Aharon-Peretz, Eldad J Dann
Cancer-related cognitive impairment (CRCI) is commonly reported post-chemotherapy in adults with solid tumours. Hodgkin lymphoma (HL) mostly affects young adults. Data regarding CRCI in HL survivors (HLS) are scarce. The current study aimed to objectively assess CRCI incidence and characteristics in HLS. HLS, who completed first-line (chemotherapy ± radiation) therapy and remained in complete remission for 6 months to 5 years from therapy end, were evaluated. Age- and education-matched healthy individuals served as controls (n = 14)...
September 2018: British Journal of Haematology
Nagi B Kumar, Angelina Fink, Silvina Levis, Ping Xu, Roy Tamura, Jeffrey Krischer
Background: Cancer related fatigue (CRF), reported in about 90% of breast cancer patients receiving chemotherapy, and has a profound impact on physical function, psychological distress and quality of life. Although several etiological factors such as anemia, depression, chronic inflammation, neurological pathology and alterations in metabolism have been proposed, the mechanisms of CRF are largely unknown. Methods: We conducted a pilot, prospective, case-control study to estimate the magnitude of change in thyroid function in breast cancer patients from baseline to 24 months, compared to cancer-free, age-matched controls...
May 22, 2018: Oncotarget
Soichiro Sasaki, Tomohisa Baba, Hayato Muranaka, Yamato Tanabe, Chiaki Takahashi, Seiichi Matsugo, Naofumi Mukaida
Adjuvant chemotherapy is used for human breast cancer patients, even after curative surgery of primary tumor, to prevent tumor recurrence primarily as a form of metastasis. However, anticancer drugs can accelerate metastasis in several mouse metastasis models. Hence, we examined the effects of postsurgical administration with 5-fluorouracil (5-FU), doxorubicin, and cyclophosphamide, on lung metastasis process, which developed after the resection of the primary tumor arising from the orthotopic injection of a mouse triple-negative breast cancer cell line, 4T1...
July 2018: Molecular Cancer Therapeutics
Lizhou Liu, Simone Petrich, Blair McLaren, Lyndell Kelly, G David Baxter
BACKGROUND: Breast cancer patients experience various side effects during cancer therapy, often resulting in reduced quality of life and poor adherence to treatment. A limited range of proven interventions has been developed to target such side effects. While Tai Chi offers benefits for the health and well-being of breast cancer survivors, the effectiveness of Tai Chi across the treatment continuum has not been evaluated. Improved patient education and support has been suggested as a priority for breast cancer care...
March 2018: Journal of Integrative Medicine
Kikuo Nakano, Yoshihiro Kitahara, Mineyo Mito, Misato Seno, Shoji Sunada
BACKGROUND: Without explicit prognostic information, patients may overestimate their life expectancy and make poor choices at the end of life. We sought to design the Japanese version of an information aid (IA) to provide accurate information on prognosis to patients with advanced non-small-cell lung cancer (NSCLC) and to assess the effects of the IA on hope, psychosocial status, and perception of curability. METHODS: We developed the Japanese version of an IA, which provided information on survival and cure rates as well as numerical survival estimates for patients with metastatic NSCLC receiving first-line chemotherapy...
February 27, 2018: BMC Palliative Care
Nancy E Avis, Aimee Johnson, Mollie Rose Canzona, Beverly J Levine
PURPOSE: This study aims (1) to estimate percentages of partnered women who are sexually active over the first 2 years post-breast cancer diagnosis; (2) to identify factors related to sexual inactivity; and (3) to evaluate separately, among both sexually active and inactive survivors, the relation between sexual problems and treatment-related variables, symptoms, and psychosocial factors. METHODS: Longitudinal observational study of breast cancer survivors recruited within 8 months of cancer diagnosis and followed for 18 months...
August 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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