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https://read.qxmd.com/read/30771623/intestinal-intussusception-related-to-colonic-pedunculated-lipoma-a-case-report-and-review-of-the-literature
#1
Johanna Cordeiro, Leonardo Cordeiro, Paula Pôssa, Paula Candido, Alice Oliveira
INTRODUCTION: Intestinal intussusception is a relatively common cause of bowel obstruction in children, however, it is a rare clinical entity in adults. When seen in adults, it is often caused by some underlying condition, usually of malignant origin. We present a case of intestinal intussusception caused by a benign and rare condition in the gastrointestinal tract. CASE PRESENTATION: A 69-year-old male patient presented with diffuse abdominal pain for 2 months, which intensified in the last two days, associated with diarrhea, vomiting and weight loss, in addition to sporadic episodes of hematochezia...
February 10, 2019: International Journal of Surgery Case Reports
https://read.qxmd.com/read/30766740/epidemic-hysteria-following-the-national-school-deworming-day-zamboanga-peninsula-philippines-2015
#2
Johnette A Peñas, Vikki Carr de Los Reyes, Ma Nemia L Sucaldito, Julius Erving D Ballera, Herdie L Hizon, Rio L Magpantay, Vicente Y Belizario, Kenneth Hartigan-Go
Introduction: In July 2015, the Philippines conducted a school-based mass drug administration using albendazole for soil-transmitted helminths infection. Reports of adverse events were subsequently made through the event-based surveillance system, mostly from the Zamboanga Peninsula on the island of Mindanao. A team from the Epidemiology Bureau investigated the reports of adverse events following mass drug administration (AEFMDA). Methods: Five schools were identified for the investigation which comprised an unmatched case-control study, key informant interviews and laboratory examinations...
October 2018: Western Pacific Surveillance and Response Journal: WPSAR
https://read.qxmd.com/read/30747595/first-line-diagnostic-evaluation-with-mri-of-children-suspected-of-having-acute-appendicitis
#3
Raza Mushtaq, Sarah M Desoky, Frank Morello, Dorothy Gilbertson-Dahdal, Geetha Gopalakrishnan, Aaron Leetch, Srinivasan Vedantham, Bobby Kalb, Diego R Martin, Unni K Udayasankar
Background Advances in abdominal MRI have enabled rapid, free-breathing imaging without the need for intravenous or oral contrast material. The use of MRI as the primary imaging modality for suspected appendicitis has not been previously studied. Purpose To determine the diagnostic performance of MRI as the initial imaging modality in children suspected of having acute appendicitis. Materials and Methods The study included consecutive patients 18 years of age and younger presenting with acute abdominal pain at a tertiary care institution from January 2013 through June 2016 who subsequently underwent an unenhanced MRI examination as the primary diagnostic imaging modality...
February 12, 2019: Radiology
https://read.qxmd.com/read/30739935/analgesic-effect-of-caudal-bupivacaine-with-or-without-clonidine-in-pediatric-patient
#4
Sharad Khakurel, Shanta Sapkota, Anuj Jung Karki
BACKGROUND: Caudal analgesia has long been the cornerstone to successful pain management in children undergoing abdominal and lower limb surgeries. Its analgesic duration with single shot injection is however limited. So adjuvants are used with local anesthetics in an attempt to increase the duration of caudal analgesia. This study aims to investigate the duration of analgesia provided by Clonidine when added to caudal Bupivacaine. METHODS: A randomized, double blinded, comparative study was conducted on 64 patients, aged two to seven years, scheduled for unilateral inguinal hernia repair...
January 28, 2019: Journal of Nepal Health Research Council
https://read.qxmd.com/read/30735448/reduction-of-influenza-a-h3n2-associated-symptoms-by-influenza-vaccination-in-school-aged-children-during-the-2014-2015-winter-season-dominated-by-mismatched-h3n2-viruses
#5
Wei Duan, Li Zhang, Shuangsheng Wu, Chunna Ma, Ying Sun, Man Zhang, Yi Zhang, Xingxing Zhang, Quanyi Wang, Peng Yang
Background Little is known about the vaccine effectiveness (VE) in attenuating the influenza-associated symptoms in children during the 2014-2015 influenza season in Beijing, China, in which there was a mismatch between the vaccine and circulating strain. Methods This study included 210 laboratory-confirmed influenza cases among children, who were enrolled in 2014, from November 1 to December 31. Standard demographic information and clinical symptoms were recorded. Influenza vaccination was confirmed via a vaccination registry...
February 8, 2019: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/30734129/helicobacter-pylori-infection-in-children-an-overview-of-diagnostic-methods
#6
REVIEW
Parisa Sabbagh, Mostafa Javanian, Veerendra Koppolu, VeneelaKrishna Rekha Vasigala, Soheil Ebrahimpour
Children differ from adults regarding Helicobacter pylori (H. pylori) infection in many terms. H. pylori infection represents a key factor in the pathogenesis of duodenal ulcer and chronic gastritis in children. H. pylori infection causes some extraintestinal diseases as well as gastrointestinal diseases. Although, among these illnesses in children, symptoms like recurrent abdominal pain are not specific. Moreover, the role of the pathogen in the growth faltering, iron deficiency anemia, and asthma still remains controversial...
February 7, 2019: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/30733116/virulence-related-genes-are-associated-with-clinical-and-nutritional-outcomes-of-shigella-enteroinvasive-escherichia-coli-pathotype-infection-in-children-from-brazilian-semiarid-region-a-community-case-control-study
#7
Mariana Bona, Pedro Henrique Medeiros, Ana Karolina Santos, Thiago Freitas, Mara Prata, Herlice Veras, Marília Amaral, Daniel Oliveira, Alexandre Havt, Aldo Ângelo Lima
Shigella/Enteroinvasive Escherichia coli (EIEC) pathotype is a major enteropathogen associated with diarrhea and malnutrition in children from developing countries. This study aimed to correlate Shigella/EIEC virulence-related genes (VRGs) with clinical symptoms, nutritional status and coenteropathogens in children from the Brazilian semiarid region. We designed a case-control study of community diarrhea in six cities of the Brazil semiarid region with 1200 children aging 2-36 months. Standardized questionnaire was applied for collecting sociodemographic, nutritional status and clinical information of the children...
January 31, 2019: International Journal of Medical Microbiology: IJMM
https://read.qxmd.com/read/30725061/-overlapping-of-functional-gastrointestinal-disorders-in-latinamerican-schoolchildren-and-adolescents
#8
Carlos Alberto Velasco-Benítez, Carmen Rossy Ramírez-Hernández, Jairo Enrique Moreno-Gómez, Edgar Játiva-Mariño, Roberto Zablah, Laura Leticia Rodríguez-Reynosa, Sofía Araceli Leyva-Jiménez, Ricardo Chanís, Milton Mejía-Castro
INTRODUCTION: There are few studies on overlapping Functional Gastrointestinal Disorders (FGIDs). OBJECTIVE: To describe the prevalence and possible risk factors in Latin American children (Latam) to present overlapping FGIDs. PATIENTS AND METHOD: Prevalence study in Latam schoolchildren bet ween 8-18 years of age. Sociodemographic variables were included; the Rome III Criteria in Spanish were used, and overlapping FGIDs were considered when two, three or four and more FGIDs were presented in the same child...
December 2018: Revista Chilena de Pediatría
https://read.qxmd.com/read/30723978/the-diagnostic-value-of-ischaemia-modified-albumin-in-acute-abdominal-pain
#9
Fatma Sarac, Selman Yeniocak, Sevgi Buyukbese Sarsu, Kamil Sahin, Esma Yucetas, Macit Koldas, Burak Katipoglu
AIM: The differential diagnosis of paediatric patients admitted to the emergency department presenting with acute abdominal pain may be difficult. This study aims to investigate the diagnostic value of ischaemia-modified albumin (IMA) in the differential diagnosis of acute abdominal pain in children and in distinguishing surgical from non-surgical cases. METHODS: The study was conducted with a total of 152 subjects who provided informed consent, including 112 patients admitted to the paediatric emergency department and paediatric surgical clinic and 40 healthy control subjects...
February 5, 2019: Journal of Paediatrics and Child Health
https://read.qxmd.com/read/30723557/diabetic-ketoacidosis-revealing-a-severe-hypertriglyceridemia-and-acute-pancreatitis-in-type-1-diabetes-mellitus
#10
Fatima Zahra Zaher, Imane Boubagura, Sana Rafi, Ghizlane Elmghari, Nawal Elansari
Diabetic ketoacidosis (DKA) is a life-threatening acute metabolic complication occurring in patients with diabetes, especially in patients with type 1 diabetes (T1D), due to an insulin deficiency. Moderate hypertriglyceridemia is commonly observed in DKA but severe hypertriglyceridemia with a triglyceride level exceeding 10g/L is very rarely reported. We report a case of a 14-year-old boy who had type 1 diabetes for 4 years treated with insulin therapy, also having adrenal insufficiency treated with hydrocortisone who presented with ketoacidosis and excruciating abdominal pain...
2019: Case Reports in Endocrinology
https://read.qxmd.com/read/30714637/clinical-features-and-disease-severity-of-turkish-fmf-children-carrying-e148q-mutation
#11
Fatma Aydın, Nilgün Çakar, Zeynep Birsin Özçakar, Nermin Uncu, Özge Başaran, Semanur Özdel, Elif Çelikel, Atilla H Elhan, Fatoş Yalçınkaya
BACKGROUND: Familial Mediterranean fever (FMF) is the most common hereditary monogenic autoinflammatory disease caused by mutations in the MEFV gene. It is controversial whether E148Q alteration is an insignificant variant or a disease-causing mutation. The aim of this study was to evaluate the clinical features and disease severity of FMF patients carrying E148Q mutation. METHODS: Files of FMF patients were retrospectively evaluated. Patients with at least one E148Q mutation were included to the study...
February 4, 2019: Journal of Clinical Laboratory Analysis
https://read.qxmd.com/read/30706952/children-with-avoidant-restrictive-food-intake-disorder-and-anorexia-nervosa-in-a-tertiary-care-pediatric-eating-disorder-program-a-comparative-study
#12
Melissa Lieberman, Melissa E Houser, Anne-Pier Voyer, Shelley Grady, Debra K Katzman
OBJECTIVE: The purpose of this study was to examine the medical and psychological characteristics of children under the age of 13 years with avoidant restrictive food intake disorder (ARFID) and anorexia nervosa (AN) from a Canadian tertiary care pediatric eating disorders program. METHOD: Participants included 106 children assessed between 2013 and 2017 using the Diagnostic and Statistical Manual for Mental Disorders, 5th edition (DSM-5). Data were collected through clinical interviews, psychometric questionnaires, and chart review...
February 1, 2019: International Journal of Eating Disorders
https://read.qxmd.com/read/30706291/frequency-of-functional-gastrointestinal-disorders-in-children-with-familial-mediterranean-fever
#13
Rabia Miray Kisla Ekinci, Sibel Balcı, Eray Akay, Gokhan Tumgor, Dilek Dogruel, Derya Ufuk Altintas, Mustafa Yilmaz
INTRODUCTION: Familial Mediterranean fever (FMF) is characterized by self-limiting fever episodes usually accompanied by serositis, arthralgia, and arthritis. Functional gastrointestinal disorders (FGIDs) are diseases in which brain-gut axis and low-grade inflammation take part in pathogenesis. We aimed to study the FGIDs frequencies and possible risk factors for FGIDs in children with FMF. METHOD: This case-control study included 103 children with FMF followed up between July 2016 and July 2018 and 100 healthy controls...
January 31, 2019: Clinical Rheumatology
https://read.qxmd.com/read/30705964/carbon-dioxide-versus-room-air-for-colonoscopy-in-deeply-sedated-pediatric-patients-a-randomized-controlled-trial
#14
Andrea Kresz, Benjamin Mayer, Maria Zernickel, Carsten Posovszky
Background and study aims  Use of carbon dioxide (CO 2 ) instead of room air (RA) during colonoscopy in adults revealed significantly less flatulence and abdominal pain in several studies. The objectives of this study were to investigate the effects of CO 2 usage on post-interventional pain, abdominal discomfort, abdominal girth, pCO 2 levels, and narcotic requirement in deeply sedated pediatric patients. Patients and methods  A total of 97 children and adolescents aged 4 years to 17 years undergoing colonoscopy were randomized to RA or CO 2 in a prospective, randomized, controlled trial...
February 2019: Endoscopy International Open
https://read.qxmd.com/read/30702647/a-multi-institutional-case-series-with-review-of-point-of-care-ultrasound-to-diagnose-malrotation-and-midgut-volvulus-in-the-pediatric-emergency-department
#15
Angélica Marie Garcia, Imran Asad, Mark O Tessaro, Adam Sivitz, Katharine Osborn, Ashkon Shaahinfar, Stephanie K Leung, Erin Rowe, Antonio Riera
Point-of-care ultrasound can be used to screen for malrotation with and without volvulus in the newborn with bilious vomiting, as well as children with unexplained intermittent abdominal pain. We discuss cases where infants and children presenting to pediatric emergency departments with bilious vomiting and/or intermittent abdominal pain were initially screened for small bowel pathology with point-of-care ultrasound. Bedside findings suggestive of midgut volvulus were confirmed with radiology-performed ultrasound or upper gastrointestinal fluoroscopy...
January 29, 2019: Pediatric Emergency Care
https://read.qxmd.com/read/30702253/gastroenteritis-in-children
#16
Scott Hartman, Elizabeth Brown, Elizabeth Loomis, Holly Ann Russell
Acute gastroenteritis is defined as a diarrheal disease of rapid onset, with or without nausea, vomiting, fever, or abdominal pain. In the United States, acute gastroenteritis accounts for 1.5 million office visits, 200,000 hospitalizations, and 300 deaths in children each year. Evaluation of a child with acute gastroenteritis should include a recent history of fluid intake and output. Significant dehydration is unlikely if parents report no decrease in oral intake or urine output and no vomiting. The physical examination is the best way to evaluate hydration status...
February 1, 2019: American Family Physician
https://read.qxmd.com/read/30701869/the-prevalence-of-helicobacter-pylori-infection-among-urban-population
#17
T V Zhestkova, M A Butov, S V Papkov
AIM: Determination of the prevalence of Helicobacter pylori infection (H. pylori) among the urban population. MATERIALS AND METHODS: 655 people (638 adults and 17 children) were examined using the immunoassay method of quantitative detection of IgG class antibodies. RESULTS: High infection of adult residents of Ryazan H. pylori - 64,4% is established. The greatest prevalence of H. pylori infection was observed in individuals 41 to 80 years of age (66,9%)...
April 19, 2018: Terapevticheskiĭ Arkhiv
https://read.qxmd.com/read/30691878/-staphylococcal-toxic-shock-syndrome-should-be-considered-in-the-event-of-diffuse-erythema-with-fever-and-shock
#18
P-M Dugourd, A Dupont, T Hubiche, C Chiaverini, A Alkhalifa, L Roudiere, A Tristan, C-A Gustave, P Del Giudice
BACKGROUND: Toxic shock syndrome (TSS) was first described by Todd in 1978. The relevant Lancet publication reported 7 cases of children with fever, exanthema, hypotension and diarrhoea associated with multiple organ failure. An association between TSS and use of hyper-absorbent tampons in menstruating women was discovered in the 1980s. Following the market withdrawal of such tampons, TSS virtually disappeared. Herein we report a new case of TSS in a 15-year-old girl. PATIENTS AND METHODS: A 15-year-old patient was admitted to intensive care for severe sepsis and impaired consciousness associated with diffuse abdominal pain...
January 25, 2019: Annales de Dermatologie et de Vénéréologie
https://read.qxmd.com/read/30688939/evaluation-of-childhood-solid-pseudopapillary-tumors-of-the-pancreas
#19
Alper Ozcan, Ceyda Arslanoglu, Ekrem Unal, Turkan Patiroglu, Mehmet Akif Ozdemir, Kemal Deniz, Serdal Sadet Ozcan, Musa Karakukcu
OBJECTIVE: Solid pseudopapillary tumor (SPT) of the pancreas is an extremely rare primary tumor in the pediatric age group. It has a low malignant potential and the prognosis is good if radical resection of the tumor is performed. Local recurrence and distant metastasis has only rarely been reported following incomplete resection. METHODS: A retrospective review of the medical records of 6 patients diagnosed as SPT according to a histopathological examination at the Children's Hospital of Erciyes University School of Medicine between 2010 and 2017 was performed...
September 2018: Northern Clinics of Istanbul
https://read.qxmd.com/read/30684309/glibenclamide-oral-suspension-suitable-and-effective-in-patients-with-neonatal-diabetes
#20
Jacques Beltrand, Amandine Baptiste, Kanetee Busiah, Naim Bouazza, Cecile Godot, Adeline Boucheron, Zoubir Djerada, Claire Gozalo, Marianne Berdugo, Jean-Marc Tréluyer, Caroline Elie, Michel Polak
BACKGROUND: Results of genetic have led to off-label glibenclamide treatment in patients with neonatal diabetes due to potassium channel mutations. No pediatric form of glibenclamide was available. Glibenclamide was designated an orphan drug designation for neonatal diabetes and a suspension was developed. As a part of the pediatric plan investigation, we assessed its acceptability, efficiency and safety. METHODS: In this Phase II, prospective, non-randomized, single-center study, patient received glibenclamide tablets for 1 month then the suspension for 3 months...
January 26, 2019: Pediatric Diabetes
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