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CMR reference values

Zhen Zhou, Lei Xu, Rui Wang, Akos Varga-Szemes, James A Durden, U Joseph Schoepf, Zhonghua Sun, Zhanming Fan
BACKGROUND: The noninvasive equilibrium contrast-enhanced cardiac computed tomography (CCT) has potential for myocardial tissue characterization. The objective of this study was to test the feasibility of CCT-based extracellular volume (ECV) fraction in beagle models of doxorubicin-induced interstitial myocardial fibrosis, with cardiac magnetic resonance (CMR) as the reference. METHODS: This study was approved by local ethics committee. Thirteen beagles were included with ECV quantified by CCT and CMR at baseline, 16 and 24 weeks after modeling...
January 15, 2019: International Journal of Cardiology
Victor Chien-Chia Wu, Tetuji Kitano, Yosuke Nabeshima, Kyoko Otani, Pao-Hsien Chu, Masaaki Takeuchi
AIMS: Novel fully automated left chamber quantification software for three-dimensional echocardiography (3DE) has a potential for reliable measurement of left ventricular (LV) volumes and ejection fraction (LVEF). However, the optimal setting of global LV endocardial border threshold has not been settled. METHODS AND RESULTS: We performed LV volumes and LVEF analysis using fully automated left chamber quantification software (Dynamic HeartModelA.I., Philips Medical Systems) in 65 patients who had undergone both 3DE and cardiac magnetic resonance (CMR) examinations on the same day...
2019: PloS One
Dominik P Guensch, Kady Fischer, Christof Jung, Samuel Hurni, Bernhard M Winkler, Bernd Jung, Andreas P Vogt, Balthasar Eberle
BACKGROUND: The relationship between mean arterial pressure (MAP) and coronary blood flow is well described. There is autoregulation within a MAP range of 60 to 140 mmHg providing near constant coronary blood flow. Outside these limits flow becomes pressure-dependent. So far, response of myocardial oxygenation to changes in pressure and flow has been more difficult to assess. While established techniques mostly require invasive approaches, Oxygenation-Sensitive (OS) Cardiovascular Magnetic Resonance (CMR) is a technique that can non-invasively assess changes in myocardial tissue oxygenation...
2019: PloS One
Simon Greulich, Maik Backes, Hannah Steubing, Andreas Seitz, Maria Chatzitofi, Philipp Kaesemann, Florian Andre, Sebastian J Buss, Hugo A Katus, Heiko Mahrholdt
BACKGROUND: The diagnostic performance of adenosine stress cardiovascular magnetic resonance (CMR) for the detection of significant stenosis in infarct-related arteries is widely unknown. Two different types of perfusion defects can be observed: (a) larger than or (b) equal size as scar.We hypothesized that: (a) defect>scar predicts significant coronary stenosis, and (b) defect=scar predicts an unobstructed infarct-related artery, and (c) angina symptoms might be of additional value in stratification...
January 9, 2019: Coronary Artery Disease
Mohammad A Khan, Eric Y Yang, Yang Zhan, Robert M Judd, Wenyaw Chan, Faisal Nabi, John F Heitner, Raymond J Kim, Igor Klem, Sherif F Nagueh, Dipan J Shah
BACKGROUND: Routine cine cardiovascular magnetic resonance (CMR) allows for the measurement of left atrial (LA) volumes. Normal reference values for LA volumes have been published based on a group of European individuals without known cardiovascular disease (CVD) but not on one of similar United States (US) based volunteers. Furthermore, the association between grades of LA dilatation by CMR and outcomes has not been established. We aimed to assess the relationship between grades of LA dilatation measured on CMR based on US volunteers without known CVD and all-cause mortality in a large, multicenter cohort of patients referred for a clinically indicated CMR scan...
January 7, 2019: Journal of Cardiovascular Magnetic Resonance
Moises Rodriguez-Mañero, Pedro Azcárate-Agüero, Bahij Kreidieh, María Teresa Alvez, Amparo Martínez-Monzonís, Agnes Diaz-Dorronsoro, Adrian Cid-Menéndez, José Ramón González-Juanatey, Joaquin Barba-Cosials, Gregorio Rábago, Gorka Bastarrika
INTRODUCTION: We evaluate the ability of 2D non-contrast-enhanced echocardiography (CE-echo), 2DCE-echo, 3D-echo, 3D non-CE-echo, and 3DCE-echo to evaluate allograft function and dimensions in orthotropic heart transplantation (OHT). Cardiac resonance (CMR) was used as reference. METHODS: Twenty six consecutive OHT-recipients were prospectively recruited. Bland-Altman, Spearman rank, and concordance-correlation coefficients (CCC) were determined. RESULTS: Good CCCs were found between the four modalities and CMR for ejection fraction (r ≥ 0...
January 1, 2019: Echocardiography
Valentina Volpato, Victor Mor-Avi, Akhil Narang, David Prater, Alexandra Gonçalves, Gloria Tamborini, Laura Fusini, Mauro Pepi, Amit R Patel, Roberto M Lang
BACKGROUND: Although 3D echocardiography (3DE) circumvents many limitations of 2D echocardiography by allowing direct measurements of left ventricular (LV) mass, it is seldom used in clinical practice due to time-consuming analysis. A recently developed 3DE machine learning (ML) approach allows automated determination of LV mass. We aimed to evaluate the accuracy of this new approach by comparing it to cardiac magnetic resonance (CMR) reference and to conventional 3DE volumetric analysis...
December 28, 2018: Echocardiography
Marko Boban, Marinko Zulj, Vladimir Pesa, Viktor Persic, Matias Trbusic, Aleksandar Vcev
BACKGROUND Impairment of systolic function and late gadolinium enhancement (LGE) are well-known negative prognostic markers in non-ischemic cardiomyopathies (NICMPs). There is limited knowledge of the geometrical rearrangements of the ventricle volumes over size of the left atrium and their connections with systolic dysfunction and existence of LGE. MATERIAL AND METHODS Consecutive cases of NICMPs with impaired systolic function and controls were included from a computerized database of cardiac magnetic resonance exams for a 2...
December 17, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Flavio D'Ascenzi, Francesca Anselmi, Pietro Piu, Caterina Fiorentini, Salvatore Francesco Carbone, Luca Volterrani, Marta Focardi, Marco Bonifazi, Sergio Mondillo
OBJECTIVES: The aim of this meta-analysis was to derive normal reference values of biventricular size and function estimated by cardiac magnetic resonance (CMR) in competitive athletes. BACKGROUND: Exercise-induced enlargement of cardiac chambers is commonly observed in competitive athletes. However, ventricular dilatation is also a common phenotypic expression of life-threatening cardiomyopathies. The use of CMR for the exclusion of pathology is growing. However, normal reference values have not been established for athletes...
December 12, 2018: JACC. Cardiovascular Imaging
M Arunsingh, S Vaidyanathan, K E Dyker, M Sen, A F Scarsbrook, R J D Prestwich
AIM: There are few data to inform on the use of response assessment 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography-computed tomography (PET-CT) following radical radiotherapy without chemotherapy for head and neck squamous cell carcinoma (HNSCC). This retrospective study evaluated the accuracy of PET-CT in HNSCC following radical radiotherapy. MATERIALS AND METHODS: In total, 138 patients with HNSCC treated with radical radiotherapy without chemotherapy who underwent a baseline and response assessment FDG PET-CT were identified...
December 12, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
Alessio Lilli, Carlo Tessa, Jacopo Del Meglio, Luca Salvatori, Alessandro Comella, Massimo Magnacca, Rosa Poddighe, Maria Laura Canale, Gianluca Solarino, Marco T Baratto, Claudio Vignali, Giancarlo Casolo
The use of cardiac magnetic resonance (cMR) to assess remodeling and tissue characterization in primitive and secondary cardiomyopathies has progressively increased, and it carries important prognostic informations. The aim of this study was to assess the overall clinical value of cMR before implantable cardioverter defibrillator (ICD). All patients referred to our center for an ICD implantation and submitted to cMR (n = 134) were analyzed. All the cMR diagnostic findings and following clinical events were reviewed to assess clinical relevance in patients care...
December 3, 2018: American Journal of Cardiology
Philip McCall, Alvin Soosay, John Kinsella, Piotr Sonecki, Ben Shelley
Right ventricular (RV) dysfunction occurs following lung resection and is associated with post-operative complications and long-term functional morbidity. Accurate peri-operative assessment of RV function would have utility in this population. The difficulties of trans thoracic echocardiographic (TTE) assessment of RV function may be compounded following lung resection surgery and no parameters have been validated in this patient group. This study compares conventional TTE methods for assessing RV systolic function to a reference method in a lung resection population...
December 1, 2018: Echo Research and Practice
Adriana D M Villa, Laura Corsinovi, Ioannis Ntalas, Xenios Milidonis, Cian Scannell, Gabriella Di Giovine, Nicholas Child, Catarina Ferreira, Muhummad Sohaib Nazir, Julia Karady, Esmeralda Eshja, Viola De Francesco, Nuno Bettencourt, Andreas Schuster, Tevfik F Ismail, Reza Razavi, Amedeo Chiribiri
BACKGROUND: Clinical evaluation of stress perfusion cardiovascular magnetic resonance (CMR) is currently based on visual assessment and has shown high diagnostic accuracy in previous clinical trials, when performed by expert readers or core laboratories. However, these results may not be generalizable to clinical practice, particularly when less experienced readers are concerned. Other factors, such as the level of training, the extent of ischemia, and image quality could affect the diagnostic accuracy...
November 19, 2018: Journal of Cardiovascular Magnetic Resonance
Alejandra García-Baizán, Maite Millor, Pablo Bartolomé, Ana Ezponda, Jesús C Pueyo, Juan J Gavira, Gorka Bastarrika
To evaluate the vasodilator effect of adenosine triphosphate (ATP) compared with adenosine in stress perfusion cardiac magnetic resonance (CMR) examinations. A total of thirty-three patients underwent clinically indicated stress/rest perfusion CMR examination following intravenous injection of a total dose of 0.2 mmol/kg of gadobutrol. Individuals were randomly assigned to ATP (160 mcg/kg/min) or adenosine (140 mcg/kg/min). The vasodilator effect of both drugs was analyzed by comparing differences in heart rate, symptoms during stress, and semiquantitative myocardial and splenic perfusion parameters, including time, time to peak, upslope, myocardial perfusion reserve index, tissue perfusion values, splenic and myocardial signal intensity ratios, and splenic-to-myocardial signal intensity ratios...
November 13, 2018: International Journal of Cardiovascular Imaging
Zhiyong Chen, Bin Sun, Qing Duan, Yunjing Xue, Lianglong Chen
To evaluate the accuracy of contrast-enhanced whole-heart magnetic resonance coronary angiography at 3.0T for assessing significant stenosis (≥50% lumen diameter reduction) in patients with myocardial infarction, by using conventional coronary artery angiography as the reference standard, and also test the performance of that for the detection and assessment of chronic myocardial infarction (MI), compared with standard delayed-enhancement coronary magnetic resonance (DE-CMR) for the determination of infarct size...
November 2018: Medicine (Baltimore)
Jee Young Min, Sung Min Ko, In Young Song, Jung Geun Yi, Hweung Kon Hwang, Je Kyoun Shin
Objective: To compare the diagnostic performance of cardiovascular magnetic resonance (CMR) myocardial perfusion at 1.5- and 3-tesla (T) for detecting significant coronary artery disease (CAD), with invasive coronary angiography (ICA) as the reference method. Materials and Methods: We prospectively enrolled 281 patients (age 62.4 ± 8.3 years, 193 men) with suspected or known CAD who had undergone 1.5T or 3T CMR and ICA. Two independent radiologists interpreted perfusion defects...
November 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
Tar-Choon Aw, Wei-Ting Huang, Thu-Thao Le, Chee-Jian Pua, Briana Ang, Soon-Kieng Phua, Khung-Keong Yeo, Stuart A Cook, Calvin W L Chin
The 99th percentile upper reference limits (URL) of high-sensitivity cardiac troponin (hs-cTn) in healthy subjects are essential for diagnosis and management of cardiovascular diseases. Unless screened stringently, subclinical disease affects the derived URL. In 779 healthy subjects(49% males; 17-88 years) screened by cardiovascular magnetic resonance (CMR), the gold standard for assessing cardiac volumes and myocardial mass; and estimated glomerular filtration rate (eGFR), the 99th percentile URL of hsTnT (Roche) and hs-cTnI (Abbott) were similar to the published URL...
October 18, 2018: Scientific Reports
Chrysanthos Grigoratos, Giancarlo Todiere, Giovanni Donato Aquaro, Andrea Barison
Cardiac palpitations secondary to ventricular ectopic beats are a frequent clinical indication for a cardiac magnetic resonance (CMR) scan. CMR has already demonstrated its additive diagnostic value in patients with frequent arrhythmias even when echocardiogram appears normal. Hereby, we describe a case of a middle-aged male patient referred to our laboratory because of frequent ventricular ectopic beats and an inconclusive echocardiogram due to an extremely poor acoustic window. A diagnosis of pericardial agenesis (PA) was made explaining patient symptoms and arrhythmias previously detected...
July 2018: Journal of Cardiovascular Echography
Idan Roifman, Feng Qiu, Kim A Connelly, Graham A Wright, Michael Farkouh, Laura Jimenez-Juan, Harindra C Wijeysundera
OBJECTIVES: Cardiovascular magnetic resonance (CMR) imaging is the gold-standard test for the assessment of heart function. Despite its importance, many jurisdictions lack specific billing codes that can be used to identify patient receipt of CMR in administrative databases, limiting the ability to perform 'big data' CMR studies. Our objective was to identify the optimal billing code combination to identify patients who underwent CMR using administrative data in Ontario. DESIGN: Retrospective cohort study...
October 8, 2018: BMJ Open
Massimo Imazio, Gloria Angelico, Monica Andriani, Luisa Lobetti-Bodoni, Ottavio Davini, Carla Giustetto, Mauro Rinaldi
Recent data suggest that myocardial septal late gadolinium enhancement (LGE) may have an independent prognostic value in patients with acute myocarditis undergoing cardiac magnetic resonance (CMR). Aim of the present study is to evaluate its prevalence and prognostic implications in these patients with or without preserved LV function. Retrospective cohort study including all cases of clinically suspected acute myocarditis referred for CMR. A diagnosis of acute myocarditis was confirmed by CMR according to Lake Louise Criteria...
September 13, 2018: American Journal of Cardiology
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