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CMR Feature Tracking

Malgorzata Wamil, Alessandra Borlotti, Dan Liu, André Briosa E Gala, Alessia Bracco, Mohammad Alkhalil, Giovanni Luigi De Maria, Stefan K Piechnik, Vanessa M Ferreira, Adrian P Banning, Rajesh K Kharbanda, Stefan Neubauer, Robin P Choudhury, Keith M Channon, Erica Dall'Armellina
Early risk stratification after ST-segment-elevation myocardial infarction (STEMI) is of major clinical importance. Strain quantifies myocardial deformation and can demonstrate abnormal global and segmental myocardial function in acute ischaemia. Native T1-mapping allows assessment of the severity of acute ischemic injury, however its clinical applicability early post MI is limited by the complex dynamic changes happening in the myocardium post MI. We aimed to explore relationship between T1-mapping and feature tracking imaging, to establish whether combined analysis of these parameters could predict recovery after STEMI...
February 16, 2019: International Journal of Cardiovascular Imaging
Laura Houard, Marie-Bénédicte Benaets, Christophe de Meester de Ravenstein, Michel F Rousseau, Sylvie A Ahn, Mihaela-Silvia Amzulescu, Clotilde Roy, Alisson Slimani, David Vancraeynest, Agnès Pasquet, Jean-Louis J Vanoverschelde, Anne-Catherine Pouleur, Bernhard L Gerber
OBJECTIVES: This study sought to compare the prognostic value of 2-dimensional (2D) right ventricular (RV) speckle tracking (STE) against cardiac magnetic resonance (CMR) RV ejection fraction (EF) and feature tracking (FT) and conventional echocardiographic parameters on overall and cardiovascular (CV) survival in patients with heart failure with reduced EF (HFrEF). BACKGROUND: Prior works showed that RV systolic function predicts prognosis in HFrEF. 2D RVSTE had recently been proposed as new echocardiographic method to evaluate RV dysfunction...
February 11, 2019: JACC. Cardiovascular Imaging
Lukas Chmielewski, Michael Bietenbeck, Alexandru Patrascu, Sabine Rösch, Udo Sechtem, Ali Yilmaz, Anca-Rezeda Florian
BACKGROUND: Cardiac involvement in myotonic dystrophy type 1 (MD1) includes conduction disease, arrhythmias, and left-ventricular (LV) systolic dysfunction leading to an increased sudden cardiac death risk. An understanding of the interplay between electrical and structural myocardial changes could improve the prediction of adverse cardiac events. We aimed to explore the relationship between signs of cardiomyopathy by conventional and advanced cardiovascular magnetic resonance (CMR), and electrical abnormalities in MD1...
February 14, 2019: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Rocio Hinojar, Jose Luis Zamorano, MªAngeles Fernández-Méndez, Amparo Esteban, Maria Plaza-Martin, Ariana González-Gómez, Alejandra Carbonell, Luis Miguel Rincón, Jose Julio Jiménez Nácher, Covadonga Fernández-Golfín
Left atrium (LA) size has an important role in determining prognosis and risk stratification in hypertrophic cardiomyopathy (HCM). Cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) is a novel technique for the quantification of LA function. Our aim was first to evaluate LA function by CMR-FT and volumetric analysis in patients with HCM; and secondly we sought to determine the association of LA-longitudinal strain (LA-LS) with major cardiovascular outcomes, particularly all cause mortality and heart failure...
January 31, 2019: International Journal of Cardiovascular Imaging
Victor Chien-Chia Wu, Tetuji Kitano, Yosuke Nabeshima, Kyoko Otani, Pao-Hsien Chu, Masaaki Takeuchi
AIMS: Novel fully automated left chamber quantification software for three-dimensional echocardiography (3DE) has a potential for reliable measurement of left ventricular (LV) volumes and ejection fraction (LVEF). However, the optimal setting of global LV endocardial border threshold has not been settled. METHODS AND RESULTS: We performed LV volumes and LVEF analysis using fully automated left chamber quantification software (Dynamic HeartModelA.I., Philips Medical Systems) in 65 patients who had undergone both 3DE and cardiac magnetic resonance (CMR) examinations on the same day...
2019: PloS One
Sören J Backhaus, Georg Metschies, Marcus Billing, Johannes T Kowallick, Roman J Gertz, Tomas Lapinskas, Burkert Pieske, Joachim Lotz, Boris Bigalke, Shelby Kutty, Gerd Hasenfuß, Philipp Beerbaum, Sebastian Kelle, Andreas Schuster
BACKGROUND: Cardiovascular magnetic resonance feature tracking (CMR-FT) is increasingly used for myocardial deformation assessment including ventricular strain, showing prognostic value beyond established risk markers if used in experienced centres. Little is known about the impact of appropriate training on CMR-FT performance. Consequently, this study aimed to evaluate the impact of training on observer variance using different commercially available CMR-FT software. METHODS: Intra- and inter-observer reproducibility was assessed prior to and after dedicated one-hour observer training...
2019: PloS One
Sören J Backhaus, Thomas Stiermaier, Torben Lange, Amedeo Chiribiri, Johannes Uhlig, Anne Freund, Johannes T Kowallick, Roman J Gertz, Boris Bigalke, Adriana Villa, Joachim Lotz, Gerd Hasenfuß, Holger Thiele, Ingo Eitel, Andreas Schuster
Aims: The exact pathophysiology of Takotsubo syndrome (TTS) remains not fully understood with most studies focussing on ventricular pathology. Since atrial involvement may have a significant role, we assessed the diagnostic and prognostic potential of atrial cardiovascular magnetic resonance feature tracking (CMR-FT) in TTS. Methods and results: This multicentre study recruited 152 TTS patients who underwent CMR on average within 3 days after hospitalization. Reservoir [total strain εs and peak positive strain rate (SR) SRs], conduit (passive strain εe and peak early negative SRe), and booster pump function (active strain εa and peak late negative SRa) were assessed in a core laboratory...
January 10, 2019: European Heart Journal Cardiovascular Imaging
Pier Giorgio Masci, Anna Giulia Pavon, Gregoire Berchier, Juerg Schwitter
BACKGROUND: Recent autopsy studies found microvascular rarefaction in remodeled myocardium of patients who died of heart failure with preserved ejection-fraction (HFpEF). This condition has not been investigated so far by non-invasive methods in patients with HFpEF. The aim was to quantify the intravascular volume (IVV) compartment by CMR in HFpEF patients. METHODS: In two separate CMR examinations, HFpEF patients (n = 6; 12 examinations) and post-myocardial infarction patients (post-MI; n = 6; 12 examinations) were studied with T1 -mapping (MOLLI-sequence) before and after IV bolus of 0...
January 5, 2019: BMC Medical Imaging
Masliza Mahmod, Nikhil Pal, Jennifer Rayner, Cameron Holloway, Betty Raman, Sairia Dass, Eylem Levelt, Rina Ariga, Vanessa Ferreira, Rajarshi Banerjee, Jurgen E Schneider, Christopher Rodgers, Jane M Francis, Theodoros D Karamitsos, Michael Frenneaux, Houman Ashrafian, Stefan Neubauer, Oliver Rider
BACKGROUND: Heart failure (HF) is characterized by altered myocardial substrate metabolism which can lead to myocardial triglyceride accumulation (steatosis) and lipotoxicity. However its role in mild HF with preserved ejection fraction (HFpEF) is uncertain. We measured myocardial triglyceride content (MTG) in HFpEF and assessed its relationships with diastolic function and exercise capacity. METHODS: Twenty seven HFpEF (clinical features of HF, left ventricular EF >50%, evidence of mild diastolic dysfunction and evidence of exercise limitation as assessed by cardiopulmonary exercise test) and 14 controls underwent 1 H-cardiovascular magnetic resonance spectroscopy (1 H-CMRS) to measure MTG (lipid/water, %), 31 P-CMRS to measure myocardial energetics (phosphocreatine-to-adenosine triphosphate - PCr/ATP) and feature-tracking cardiovascular magnetic resonance (CMR) imaging for diastolic strain rate...
December 24, 2018: Journal of Cardiovascular Magnetic Resonance
Shuang Leng, Xiaodan Zhao, Angela S Koh, Lei Zhao, John C Allen, Ru-San Tan, Xiaohai Ma, Liang Zhong
Background: We determined the age-related changes in atrioventricular junction (AVJ) velocities and displacements by feature tracking cardiovascular magnetic resonance (FT-CMR) in a healthy community-based population. We also investigated the importance of age-matching for the identification of altered AVJ dynamics. Methods: FT-CMR was performed in 230 controls (18-78 years) and in two patient groups each consisting of 40 subjects (group 1: 23-55 years, group 2: 56-80 years)...
March 2019: IJC Heart & Vasculature
Mareike Gastl, Din-E-Mujahid Mohammad Faruque Osmany, Robert Manka
CLINICAL INTRODUCTION: A 71-year-old woman was diagnosed with systemic vasculitis in 2009 and received specific therapy (corticosteroids, cytostatic agents or rituximab in differing order). A transthoracic echocardiography (TTE) in 2013 for follow-up purposes of complications showed hyperechogenic endocardium of the whole left ventricular (LV) apex and cardiac MRI (CMR) was followed to further examine this finding. Using CMR, an apical LV thrombus was detected along with abnormal signal intensities within the endocardium (figure 1A)...
November 15, 2018: Heart: Official Journal of the British Cardiac Society
Simone Romano, Robert M Judd, Raymond J Kim, Han W Kim, John F Heitner, Dipan J Shah, Richard B Devereux, Pablo Salazar, Michael Trybula, Richard C Chia, Kaleigh Evans, Afshin Farzaneh-Far
OBJECTIVES: This study sought to evaluate the prognostic value of cardiac magnetic resonance (CMR)-derived mitral annular plane systolic excursion (MAPSE) in a large multicenter population of patients with hypertension. BACKGROUND: In patients with hypertension, cardiac abnormalities are powerful predictors of adverse outcomes. Long-axis mitral annular movement plays a fundamental role in cardiac mechanics and is an early marker for a number of pathological processes...
October 26, 2018: JACC. Cardiovascular Imaging
Shuang Leng, Ru-San Tan, Xiaodan Zhao, John C Allen, Angela S Koh, Liang Zhong
BACKGROUND: Abnormal left atrial (LA) function is a marker of cardiac dysfunction and adverse cardiovascular outcome, but is difficult to assess, and hence not, routinely quantified. We aimed to determine the feasibility and effectiveness of a fast method to measure long-axis LA strain and strain rate (SR) with standard cardiovascular magnetic resonance (CMR) compared to conventional feature tracking (FT) derived longitudinal strain. METHODS: We studied 50 normal controls, 30 patients with hypertrophic cardiomyopathy, and 100 heart failure (HF) patients, including 40 with reduced ejection fraction (HFrEF), 30 mid-range ejection fraction (HFmrEF) and 30 preserved ejection fraction (HFpEF)...
November 5, 2018: Journal of Cardiovascular Magnetic Resonance
Inna Y Gong, Geraldine Ong, Christine Brezden-Masley, Vinita Dhir, Djeven P Deva, Kelvin K W Chan, John J Graham, Chi-Ming Chow, Paaladinesh Thavendiranathan, Day Dai, Ming-Yen Ng, Joseph J Barfett, Kim A Connelly, Andrew T Yan
We evaluated temporal changes in early diastolic strain rates by cardiovascular magnetic resonance (CMR) as an early detector of trastuzumab-induced ventricular dysfunction. We conducted a prospective, multi-centre, longitudinal observational study of 41 trastuzumab-treated breast cancer women who underwent serial CMR (baseline, 6, 12, and 18 months). Two blinded readers independently measured left ventricular ejection fraction (LVEF), peak systolic strain parameters (global longitudinal strain [GLS] and global circumferential strain [GCS]), and early diastolic strain rate parameters (global longitudinal diastolic strain rate [GLSR-E], global circumferential diastolic strain rate [GCSR-E], and global radial diastolic strain rate [GRSR-E]), by feature tracking (FT-CMR) using CMR42...
November 2, 2018: International Journal of Cardiovascular Imaging
Csilla Czimbalmos, Ibolya Csecs, Zsofia Dohy, Attila Toth, Ferenc Imre Suhai, Andreas Müssigbrodt, Orsolya Kiss, Laszlo Geller, Bela Merkely, Hajnalka Vago
Both, arrhythmogenic right ventricular cardiomyopathy (ARVC) and regular training are associated with right ventricular (RV) remodelling. Cardiac magnetic resonance (CMR) is given an important role in the diagnosis of ARVC in current task force criteria (TFC), however, they contain no cut-off values for athletes. We aimed to confirm the added value of feature tracking and to provide new cut-off values to differentiate between ARVC and athlete's heart. Healthy athletes with training of minimal 15 h/week (n = 34), patients with definite ARVC (n = 34) and highly trained athletes with ARVC (n = 8) were examined by CMR...
October 31, 2018: International Journal of Cardiovascular Imaging
Snigdha Jain, Daniel Kuriakose, Ilaina Edelstein, Bilal Ansari, Garrett Oldland, Swetha Gaddam, Khuzaima Javaid, Pritika Manaktala, Jonathan Lee, Rachana Miller, Scott R Akers, Julio A Chirinos
OBJECTIVES: This study researched right atrial (RA) deformation indexes and their association with all-cause mortality among subjects with or without heart failure (HF). BACKGROUND: Although left atrial dysfunction is well described in HF, patterns of RA dysfunction and their prognostic implications are unclear. Cardiac magnetic resonance (CMR) imaging can provide excellent visualization of the RA. We used CMR to characterize RA phasic function in HF and to assess its prognostic implications...
October 12, 2018: JACC. Cardiovascular Imaging
Aleksandra Trzebiatowska-Krzynska, Eva Swahn, Lars Wallby, Niels Erik Nielsen, Carl Johan Carlhäll, Lars Brudin, Jan E Engvall
BACKGROUND: Prior studies suggested that myocardial deformation is superior to conventional measures for assessing ventricular function. This study aimed to evaluate right ventricular (RV) myocardial deformation in response to increased afterload. Patients with the RV in the systemic position were compared with patients with the RV in the sub-pulmonic position with normal or only slightly elevated systolic right ventricular pressure. Correlations between global longitudinal strain (GLS), radial strain, atrioventricular plane displacement (AVPD), and exercise capacity were evaluated...
2018: PloS One
Junping Peng, Xiaodan Zhao, Lei Zhao, Zhanming Fan, Zheng Wang, Hui Chen, Shuang Leng, John Allen, Ru-San Tan, Angela S Koh, Xiaohai Ma, Mingwu Lou, Liang Zhong
Reference values on atrial and ventricular strain from cardiovascular magnetic resonance (CMR) are essential in identifying patients with impaired atrial and ventricular function. However, reference values have not been established for Chinese subjects. One hundred and fifty healthy volunteers (75 Males/75 Females; 18-82 years) were recruited. All underwent CMR scans with images acceptable for further strain analysis. Subjects were stratified by age: Group 1, 18-44 years; Group 2, 45-59 years; Group 3, ≥60 years...
2018: Frontiers in Physiology
Vicente Bodi
No abstract text is available yet for this article.
September 6, 2018: JACC. Cardiovascular Imaging
Tomaž Podlesnikar, Gonzalo Pizarro, Rodrigo Fernández-Jiménez, Jose M Montero-Cabezas, Javier Sánchez-González, Chiara Bucciarelli-Ducci, Nina Ajmone Marsan, Zlatko Fras, Jeroen J Bax, Valentin Fuster, Borja Ibáñez, Victoria Delgado
OBJECTIVES: This study sought to evaluate the effect of early intravenous metoprolol on left ventricular (LV) strain assessed with feature-tracking cardiovascular magnetic resonance (CMR). BACKGROUND: Early intravenous metoprolol before primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) portends better outcomes in the METOCARD-CNIC (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction) trial...
September 6, 2018: JACC. Cardiovascular Imaging
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