Ana Luíza A R Martin, Raimundo Luiz Silva Pereira, Janaína Esmeraldo Rocha, Pablo A M Farias, Thiago S Freitas, Francisco Rodrigo de Lemos Caldas, Fernando G Figueredo, Nadghia Figueiredo Leite Sampaio, Cícera Datiane de Morais Oliveira-Tintino, Saulo Relison Tintino, Gabriel Costa A da Hora, Maria Carolina Pacheco Lima, Irwin Rose A de Menezes, Diogo T Carvalho, Henrique D M Coutinho, Marta M F Fonteles
The occurrence of bacterial resistance has been increasing, compromising the treatment of various infections. The high virulence of Staphylococcus aureus allows for the maintenance of the infectious process, causing many deaths and hospitalizations. The MepA and NorA efflux pumps are transporter proteins responsible for expelling antimicrobial agents such as fluoroquinolones from the bacterial cell. Coumarins are phenolic compounds that have been studied for their diverse biological actions, including against bacteria...
March 20, 2024: Microbial Pathogenesis