Hirokazu Yano, Wataru Hayashi, Sayoko Kawakami, Sadao Aoki, Eiko Anzai, Hui Zuo, Norikazu Kitamura, Aki Hirabayashi, Toshiki Kajihara, Shizuo Kayama, Yo Sugawara, Koji Yahara, Motoyuki Sugai
Japan is a country with an approximate 10% prevalence rate of carbapenem-resistant Pseudomonas aeruginosa (CRPA). Currently, a comprehensive overview of the genotype and phenotype patterns of CRPA in Japan is lacking. Herein, we conducted genome sequencing and quantitative antimicrobial susceptibility testing for 382 meropenem-resistant CRPA isolates that were collected from 78 hospitals across Japan from 2019 to 2020. CRPA exhibited susceptibility rates of 52.9%, 26.4%, and 88.0% against piperacillin-tazobactam, ciprofloxacin, and amikacin, respectively, whereas 27...
April 2, 2024: Antimicrobial Agents and Chemotherapy