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Lymphedema breast cancer

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https://read.qxmd.com/read/30770083/-general-practitioner-questionnaire-concerning-upper-limb-lymphedema-after-breast-cancer
#1
M Simon, S Vignes
INTRODUCTION: In France, breast cancer is the most frequent cancer in women. Lymphedema, the main complication, is poorly known. The objective of this study was to assess the state of knowledge of upper limb lymphedema (risk factors, complications, treatment) after treatment of breast cancer among general practitioners from the Haute-Normandie and Île-de-France regions. MATERIALS AND METHODS: A cross-sectional study with 23 closed questions was sent by email to 490 practicing doctors...
February 2019: Journal de Médecine Vasculaire
https://read.qxmd.com/read/30763181/lymphedema-after-breast-cancer-treatment
#2
(no author information available yet)
New England Journal of Medicine, Volume 380, Issue 7, Page 694-694, February 2019.
February 14, 2019: New England Journal of Medicine
https://read.qxmd.com/read/30759059/revision-of-the-lymphedema-functioning-disability-and-health-questionnaire-for-upper-limb-lymphedema-lymph-icf-ul-reliability-and-validity
#3
Tessa De Vrieze, Lore Vos, Nick Gebruers, An De Groef, Lore Dams, Elien Van der Gucht, Ines Nevelsteen, Nele Devoogdt
BACKGROUND: Lymphedema is associated with significant physical and psychosocial problems. The Lymphedema Functioning, Disability and Health questionnaire for upper limb lymphedema is a valid and reliable tool quantifying the amount of problems in functioning in patients with breast cancer-related lymphedema. Patients suggested a revision of the scoring system to facilitate completion of the questionnaire. Therefore, adjustment of the questionnaire was carried out by implementing a numeric rating scale instead of the existing visual analog scale...
February 13, 2019: Lymphatic Research and Biology
https://read.qxmd.com/read/30735097/easy-volumeter-in-detection-of-breast-cancer-related-lymphedema-a-validity-study
#4
Onur Engin, Elif Akalın, Efe Sarıbay, Ceren Aslan, Ebru Şahin, Serap Alper
Aim and Hypothesis: The standard volumeter is heavy and fragile, and using the same volumeter for different patients can result in hygiene problems. These disadvantages point to the need for the development of a new model of volumeter. The new volumeter put forward in this study is lighter, smaller, sturdier, and easier to clean, while also having its own scale. In this study, the validity of this newly designed volumeter is investigated. MATERIALS AND METHODS: In the first step, the volume of standard cylinders was measured thrice using a standard volumeter and an easy-measurement volumeter, after which a total of 30 arm volumes of 15 volunteers were measured...
February 8, 2019: Lymphatic Research and Biology
https://read.qxmd.com/read/30712198/efficacy-of-self-administered-complex-decongestive-therapy-on-breast-cancer-related-lymphedema-a-single-blind-randomized-controlled-trial
#5
M B Ligabue, I Campanini, P Veroni, A Cepelli, M Lusuardi, A Merlo
PURPOSE: After surgery, breast cancer-related lymphedema (BCRL) is a frequent chronic condition. The complex decongestive therapy (CDT) delivered by physiotherapists at hospitals is the state-of-the-art treatment choice. As lymphedema requires continuous management, we designed a 1-month-long course to train women to professionally carry out a self-administered CDT (saCDT) and tested its efficacy while keeping the benefits of CDT. METHODS: Consecutive patients treated with CDT over a 1-year period at an Italian facility were randomly assigned to either experimental (EXP, saCDT course) or control (CTRL, usual care) group...
February 2, 2019: Breast Cancer Research and Treatment
https://read.qxmd.com/read/30702006/effect-of-progressive-resistance-training-on-health-related-quality-of-life-in-the-first-year-after-breast-cancer-surgery-results-from-a-randomized-controlled-trial
#6
Gunn Ammitzbøll, Trille Kristina Kjær, Christoffer Johansen, Charlotte Lanng, Elisabeth Wreford Andersen, Niels Kroman, Bo Zerahn, Ole Hyldegaard, Pernille Envold Bidstrup, Susanne Oksbjerg Dalton
AIMS: To examine the effect of progressive resistance training (PRT) on health related quality of life and a predefined symptom cluster of pain-sleep-fatigue. METHODS: This study was a planned secondary analysis of a randomized controlled trial examining the effect of PRT on prevention of arm lymphedema in a population of women between 18 and 75 years undergoing breast cancer surgery with axillary lymph node dissection. Participants were allocated by computer randomization to usual care control or a PRT intervention in a 1:1 ratio...
January 31, 2019: Acta Oncologica
https://read.qxmd.com/read/30694729/assessment-of-upper-extremity-swelling-among-breast-cancer-survivors-with-a-commercial-infrared-sensor
#7
Iris M Lu, J Brandon Dixon
BACKGROUND: There are various methods of detecting and monitoring arm lymphedema after breast cancer (BC) treatment. Using volumetric measurements is the most common method performed clinically in the United States, and several techniques exist. Recently, the use of infrared cameras has been explored by several groups. This study shows the use of this technology and its ability to assess arm volume measurements comparable to the Perometer while being more inexpensive, having a smaller footprint in clinics, and being easy to use...
January 29, 2019: Lymphatic Research and Biology
https://read.qxmd.com/read/30682851/breast-cancer-systemic-treatments-and-upper-limb-lymphedema-a-risk-assessment-platform-encompassing-tumor-specific-pathological-features-reveals-the-potential-role-of-trastuzumab
#8
Marco Invernizzi, Anna Michelotti, Marianna Noale, Gianluca Lopez, Letterio Runza, Massimo Giroda, Luca Despini, Concetta Blundo, Stefania Maggi, Donatella Gambini, Nicola Fusco
Breast cancer related lymphedema (BCRL) is frequent but strategies for an individualized risk assessment are lacking. We aimed to define whether tumor-specific pathological features, coupled with clinical and therapeutic data, could help identify patients at risk. Data from 368 patients with node-positive breast cancers were retrospectively collected, including 75 patients with BCRL (0.4⁻25.6 years follow-up). BCRL was assessed during the standard follow-up oncology visits using the circumferential measurement...
January 24, 2019: Journal of Clinical Medicine
https://read.qxmd.com/read/30672753/the-new-possibility-of-lymphoscintigraphy-to-guide-a-clinical-treatment-for-lymphedema-in-patient-with-breast-cancer
#9
Kwan Sik Seo, Minseok Suh, Sunmok Hong, Gi Jeong Cheon, Shi-Uk Lee, Gwang Pyo Jung
OBJECTIVES: Lymphedema is a chronic disease that occurs frequently after breast cancer treatment. For the treatment of lymphedema, surgical approach such as vascularized lymph node transfer and super-microscopic lymphovenous anastomosis surgery is well established. Complex decongestive therapy (CDT) and sympathetic ganglion block (SGB) are two non-surgical therapeutic options. This study aimed to evaluate the effectiveness of lymphoscintigraphy in guiding the selection of the optimal non-surgical treatment in lymphedema...
January 18, 2019: Clinical Nuclear Medicine
https://read.qxmd.com/read/30656093/comparisons-of-submental-and-groin-vascularized-lymph-node-flaps-transfer-for-breast-cancer-related-lymphedema
#10
Olivia A Ho, Chia-Yu Lin, Marco Pappalardo, Ming-Huei Cheng
Background: The vascularized groin and submental lymph node (VGLN and VSLN) flaps are valuable options in the treatment of lymphedema. This study was to compare outcomes between VGLN and VSLN transfers for breast cancer-related lymphedema. Methods: Between January 2008 and December 2016, VGLN and VSLN transfers for upper limb lymphedema were compared including flap characteristics, flap elevation time, complications, and limb circumference changes. Results: All flaps survived...
December 2018: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/30638810/breast-cancer-treatment-related-lymphedema-bcrl-an-overview-of-the-literature-and-updates-in-microsurgery-reconstructions
#11
REVIEW
Bayu Brahma, Takumi Yamamoto
Breast cancer is the most common cancer in Dharmais hospital. The treatment can give rise to breast cancer treatment-related lymphedema (BCRL) that will cause significant morbidities. Based on author's (BB) patient series in Dharmais hospital, BCRL occurred in 27.7% after axillary lymph nodes dissection (ALND). The development of diagnostic modalities as well as lymphatic microsurgery have become promising instruments for lymphedema treatment. To date, modern approach of lymphedema care and surgical intervention have not been recognized and established in Indonesia...
January 4, 2019: European Journal of Surgical Oncology
https://read.qxmd.com/read/30638093/resistance-exercise-and-breast-cancer-related-lymphedema-a-systematic-review-update
#12
Timothy Hasenoehrl, Mohammad Keilani, Stefano Palma, Richard Crevenna
BACKGROUND: Purpose of this systematic review update was analyzing resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status. Articles published until 31 September 2017 were included. METHODS: A systematic literature search was conducted utilizing PubMed, MEDLINE, and EMBASE databases. Included articles were analyzed regarding their level of evidence and their methodological quality using the Cochrane risk of bias tool...
January 13, 2019: Disability and Rehabilitation
https://read.qxmd.com/read/30633334/progressive-resistance-training-to-prevent-arm-lymphedema-in-the-first-year-after-breast-cancer-surgery-results-of-a-randomized-controlled-trial
#13
Gunn Ammitzbøll, Christoffer Johansen, Charlotte Lanng, Elisabeth Wreford Andersen, Niels Kroman, Bo Zerahn, Ole Hyldegaard, Merete Celano Wittenkamp, Susanne Oksbjerg Dalton
BACKGROUND: Existing research suggests that progressive resistance training (PRT) after breast cancer (BC) surgery is safe, but the preventive effect on arm lymphedema has yet to be determined. METHODS: Women aged 18 to 75 years who were undergoing BC surgery with axillary lymph node dissection were eligible for the study. Recruited on the day of surgery, participants were allocated to intervention or usual care by computer randomization. The intervention consisted of PRT 3 times per week: in the first 20 weeks as a supervised group exercise and in the last 30 weeks as a self-administered exercise...
January 11, 2019: Cancer
https://read.qxmd.com/read/30628927/the-long-term-patency-of-lymphaticovenular-anastomosis-in-breast-cancer-related-lymphedema
#14
Harm Winters, Hanneke J P Tielemans, Arico C Verhulst, Vera A A Paulus, Nicholas J Slater, Dietmar J O Ulrich
BACKGROUND AND OBJECTIVES: Lymphedema is a condition that can greatly affect patient's quality of life. Promising results have been described with lymphaticovenular anastomosis (LVA) in the treatment of lymphedema. It is currently unknown at what rate anastomoses remain functional after a longer follow-up. The aim of this study was to determine LVA patency at 1-year follow-up. METHODS: Retrospective chart review was performed on patients who underwent LVA surgery...
February 2019: Annals of Plastic Surgery
https://read.qxmd.com/read/30607165/use-of-sentinel-lymph-node-biopsy-after-neoadjuvant-chemotherapy-in-patients-with-axillary-node-positive-breast-cancer-in-diagnosis
#15
Hee Jun Choi, Isaac Kim, Emad Alsharif, Sungmin Park, Jae-Myung Kim, Jai Min Ryu, Seok Jin Nam, Seok Won Kim, Jonghan Yu, Se Kyung Lee, Jeong Eon Lee
Purpose: This study aimed to evaluate the effects of sentinel lymph node biopsy (SLNB) on recurrence and survival after neoadjuvant chemotherapy (NAC) in breast cancer patients with cytology-proven axillary node metastasis. Methods: We selected patients who were diagnosed with invasive breast cancer and axillary lymph node metastasis and were treated with NAC followed by curative surgery between January 2007 and December 2014. We classified patients into three groups: group A, negative sentinel lymph node (SLN) status and no further dissection; group B, negative SLN status with backup axillary lymph node dissection (ALND); and group C, no residual axillary metastasis on pathology with standard ALND...
December 2018: Journal of Breast Cancer
https://read.qxmd.com/read/30604734/breast-cancer-related-lymphedema-in-postmastectomy-patients-receiving-adjuvant-irradiation-a-prospective-study
#16
Kartick Rastogi, Sandeep Jain, Aseem-Rai Bhatnagar, Shivani Gupta, Sandeep Bhaskar, R K Spartacus
CONTEXT: In India, most breast cancer patients present with advanced stage requiring postmastectomy radiotherapy. Lymphedema is a long-term side effect that causes both physical and psychological distresses. AIMS: The present prospective study was carried out to study various factors affecting breast cancer-related lymphedema (BCRL). SUBJECTS AND METHODS: From January 2015 to March 2016, 100 postmastectomy patients who received adjuvant irradiation to chest wall were selected prospectively...
April 2018: Indian Journal of Cancer
https://read.qxmd.com/read/30592710/podoplanin-tumor-lymphatics-are-rate-limiting-for-breast-cancer-metastasis
#17
Yang Chen, Doruk Keskin, Hikaru Sugimoto, Keizo Kanasaki, Patricia E Phillips, Lauren Bizarro, Arlene Sharpe, Valerie S LeBleu, Raghu Kalluri
Metastatic dissemination employs both the blood and lymphatic vascular systems. Solid tumors dynamically remodel and generate both vessel types during cancer progression. Lymphatic vessel invasion and cancer cells in the tumor-draining lymph nodes (LNs) are prognostic markers for breast cancer metastasis and patient outcome, and tumor-induced lymphangiogenesis likely influences metastasis. Deregulated tumor tissue fluid homeostasis and immune trafficking associated with tumor lymphangiogenesis may contribute to metastatic spreading; however, the precise functional characterization of lymphatic endothelial cells (LECs) in tumors is challenged by the lack of specific reagents to decipher their rate-limiting role in metastasis...
December 2018: PLoS Biology
https://read.qxmd.com/read/30580170/tackling-the-diversity-of-breast-cancer-related-lymphedema-perspectives-on-diagnosis-risk-assessment-and-clinical-management
#18
REVIEW
Anna Michelotti, Marco Invernizzi, Gianluca Lopez, Daniele Lorenzini, Francesco Nesa, Alessandro De Sire, Nicola Fusco
Breast cancer related lymphedema (BCRL) develops as a consequence of surgical treatment and/or radiation therapy in a significant number of breast cancer patients. The etiology of this condition is multifactorial and has not yet been completely elucidated. Risk factors include high body mass index, radical surgical procedures (i.e. mastectomy and axillary lymph node dissection), number of lymph nodes removed and number of metastatic lymph nodes, as well as nodal radiation, and chemotherapy. However, these predisposing factors explain only partially the BCRL occurrence, suggesting the possible involvement of individual determinants...
December 17, 2018: Breast: Official Journal of the European Society of Mastology
https://read.qxmd.com/read/30570358/interrater-and-intrarater-reliability-of-subcutaneous-echogenicity-grade-and-subcutaneous-echo-free-space-grade-in-breast-cancer-related-lymphedema
#19
Esra Giray, İlker Yağcı
BACKGROUND: Subcutaneous echogenicity grade (SEG) and subcutaneous echo-free space (SEFS) grade allow semiquantitation of nonspecific subcutaneous tissue inflammation and fluid accumulation in breast cancer-related lymphedema. However, inter- and intrarater reliability of SEG and SEFS is yet to be reported. The objective of this study is to assess inter-rater and intrarater reliability of SEG and SEFS in patients with breast cancer-related lymphedema. METHODS AND RESULTS: Two physiatrists performed SEG and SEFS grade to determine inter-rater and intrarater reliability...
December 20, 2018: Lymphatic Research and Biology
https://read.qxmd.com/read/30562149/optimizing-patient-positioning-to-reduce-variation-in-the-measurement-of-breast-cancer-related-lymphedema
#20
Sarah M DeSnyder, Parviz Kheirkhah, Marigold L Travis, Susan E Lilly, Isabelle Bedrosian, Thomas A Buchholz, Mark V Schaverien, Simona F Shaitelman
BACKGROUND: Prospective lymphedema screening is recommended for breast cancer patients. We observed interoperator variation in perometer-acquired arm volume measurements (P-AVMs) due to patient instability during measurements. We hypothesized that improved positioning during perometry would reduce P-AVM variability. METHODS AND RESULTS: Each arm was measured three times by each operator using a perometer. With the original configuration, P-AVM was performed by 2 operators in 30 patients and four cohorts of 5 to 6 operators in 5 volunteers...
December 18, 2018: Lymphatic Research and Biology
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