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resynchronization electrocardiographic

U H Ferdaushi, M A Ali, N Islam, S Nabi, M Islam, M S Alom, G K Paul
Cardiac resynchronization therapy (CRT) reduces symptoms and improves left ventricular function in patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony. We analyzed the clinical and echocardiographic outcome of CRT in heart failure patients. Thirty five (35) heart failure patients were included in this prospective observational study, conducted from February 2015 to February 2016 in the Department of cardiology, National Institute of Cardiology & Vascular Disease (NICVD) hospital, Dhaka, Bangladesh...
January 2019: Mymensingh Medical Journal: MMJ
S Yu Kashtanova, N A Mironova, V N Shitov, E M Gupalo, V G Kiktev, M A Saidova, S P Golitsyn
AIM: To assess the value of the complex analysis of electrocardiographic (ECG) variants and echocardiographic (echo) manifestation of left bundle branch block (LBBB) in predicting the success of cardiac resynchronization therapy (CRT). MATERIALS AND METHODS: The study included 39 patients (mean age 61.49±9.0 years) on sinus rhythm with LBBB, QRS duration ≥130 ms, left ventricular ejection fraction (LVEF) ≤35%, heart failure (HF) NYHA II-IV despite optimal pharmacological therapy during 3 month...
December 30, 2018: Terapevticheskiĭ Arkhiv
Uyên Châu Nguyên, Matthijs J M Cluitmans, Marc Strik, Justin G Luermans, Suzanne Gommers, Joachim E Wildberger, Sebastiaan C A M Bekkers, Paul G A Volders, Casper Mihl, Frits W Prinzen, Kevin Vernooy
Aims: An appropriate left ventricular (LV) lead position is a pre-requisite for response to cardiac resynchronization therapy (CRT) and is highly patient-specific. The purpose of this study was to develop a non-invasive pre-procedural CRT-roadmap to guide LV lead placement to a coronary vein in late-activated myocardium remote from scar. Methods and results: Sixteen CRT candidates were prospectively included. Electrocardiographic imaging (ECGI), computed tomography angiography (CTA), and delayed enhancement cardiac magnetic resonance imaging (DE-CMR) were integrated into a 3D cardiac model (CRT-roadmap) using anatomic landmarks from CTA and DE-CMR...
December 24, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Ahran D Arnold, Matthew J Shun-Shin, Daniel Keene, James P Howard, S M Afzal Sohaib, Ian J Wright, Graham D Cole, Norman A Qureshi, David C Lefroy, Michael Koa-Wing, Nick W F Linton, Phang Boon Lim, Nicholas S Peters, D Wyn Davies, Amal Muthumala, Mark Tanner, Kenneth A Ellenbogen, Prapa Kanagaratnam, Darrel P Francis, Zachary I Whinnett
BACKGROUND: His bundle pacing is a new method for delivering cardiac resynchronization therapy (CRT). OBJECTIVES: The authors performed a head-to-head, high-precision, acute crossover comparison between His bundle pacing and conventional biventricular CRT, measuring effects on ventricular activation and acute hemodynamic function. METHODS: Patients with heart failure and left bundle branch block referred for conventional biventricular CRT were recruited...
December 18, 2018: Journal of the American College of Cardiology
Antonius M W van Stipdonk, Iris Ter Horst, Marielle Kloosterman, Elien B Engels, Michiel Rienstra, Harry J G M Crijns, Marc A Vos, Isabelle C van Gelder, Frits W Prinzen, Mathias Meine, Alexander H Maass, Kevin Vernooy
BACKGROUND: The combination of left bundle branch block (LBBB) morphology and QRS duration is currently used to select patients for cardiac resynchronization therapy (CRT). These parameters, however, have limitations. This study evaluates the value of QRS area compared with that of QRS duration and morphology in the association with clinical and echocardiographic outcomes in a large cohort of CRT patients. METHODS: A retrospective multicentre study was conducted in 1492 CRT patients...
December 2018: Circulation. Arrhythmia and Electrophysiology
Marek Jastrzebski, Adrian Baranchuk, Kamil Fijorek, Roksana Kisiel, Piotr Kukla, Tomasz Sondej, Danuta Czarnecka
Aims: QRS narrowing with initiation of biventricular pacing might be an acute electrocardiographic indicator of correction of left bundle branch block (LBBB)-induced depolarization delay and asynchrony. However, its impact on prognosis remains controversial, especially in non-LBBB patients. Our goal was to evaluate the impact of QRS narrowing on long-term mortality and morbidity in a large cohort of patients undergoing cardiac resynchronization therapy (CRT) with different pre-implantation QRS types: LBBB, non-LBBB, and permanent right ventricular pacing...
November 6, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Michael R Gold, Yinghong Yu, Jagmeet P Singh, Ulrika Birgersdotter-Green, Kenneth M Stein, Nicholas Wold, Timothy E Meyer, Kenneth A Ellenbogen
BACKGROUND: Routine atrioventricular optimization (AVO) has not been shown to improve outcomes with cardiac resynchronization therapy (CRT). However, more recently subgroup analyses of multicenter CRT trials have identified electrocardiographic or lead positions associated with benefit from AVO. Therefore, the purpose of this analysis was to evaluate whether interventricular electrical delay modifies the impact of AVO on reverse remodeling with CRT. METHODS: This substudy of the SMART-AV trial (SMARTDELAY Determined AV Optimization) included 275 subjects who were randomized to either an electrogram-based AVO (SmartDelay) or nominal atrioventricular delay (120 ms)...
August 2018: Circulation. Arrhythmia and Electrophysiology
Marta Pombo Jiménez, Oscar Cano Pérez, Diego Lorente Carreño, Javier Chimeno García
INTRODUCTION AND OBJECTIVES: This report describes the data reported to the Spanish Pacemaker Registry concerning the activity in cardiac pacing in 2017 in Spain. METHODS: The analysis is based on the data obtained from the European Pacemaker Identification Card and the information reported by supplier companies related to global number of implanted pacemakers. RESULTS: Information was received from 106 hospitals, with a total of 12672 cards, representing the 32...
October 19, 2018: Revista Española de Cardiología
John Gorcsan, Christopher P Anderson, Bhupendar Tayal, Masataka Sugahara, John Walmsley, Randall C Starling, Joost Lumens
OBJECTIVES: In this study, the authors tested the hypotheses that the systolic stretch index (SSI) developed by computer modeling and applied using echocardiographic strain imaging may characterize the electromechanical substrate predictive of outcome following cardiac resynchronization therapy (CRT). They included patients with QRS width 120 to 149 ms or non-left bundle branch block (LBBB), where clinical uncertainty for CRT exists. They further tested the hypothesis that global longitudinal strain (GLS) has additional prognostic value...
September 12, 2018: JACC. Cardiovascular Imaging
Kelley P Anderson
BACKGROUND: The clinical significance of left bundle branch block (LBBB) has recently expanded with the discovery of a strong association with better outcomes in patients receiving cardiac resynchronization therapy. METHODS: Several milestones have contributed to the current understanding on the role of LBBB in clinical practice. RESULT: Sunao Tawara described the arrangement of components of what he called the cardiac conduction system from the atrioventricular node to the terminal Purkinje fibers that connect to the working myocardium, and his hypotheses on how it functions remain current...
August 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Benjamin J Sieniewicz, Tom Jackson, Simon Claridge, Helder Pereira, Justin Gould, Baldeep Sidhu, Bradley Porter, Steve Niederer, Cheng Yao, Christopher A Rinaldi
BACKGROUND: Cardiac resynchronization therapy (CRT) is typically delivered via quadripolar leads that allow stimulation using either true bipolar pacing, where stimulation occurs between two electrodes (BP) on the quadripolar lead, or extended bipole (EBP) left ventricular (LV) pacing, with the quadripolar electrodes and right ventricular coil acting as the cathode and anode, respectively. True bipolar pacing is associated with reductions in mortality and it has been postulated that these differences are the result of enhanced electrical activation...
August 14, 2018: Journal of Cardiovascular Electrophysiology
Mihoko Kawabata, Masahiko Goya, Yoshihide Takahashi, Shingo Maeda, Atsuhiko Yagishita, Yasuhiro Shirai, Masakazu Kaneko, Shinya Shiohira, Kenzo Hirao
In patients requiring an implantable cardioverter defibrillator (ICD), the combined use of a prior pacemaker and a subcutaneous ICD (S-ICD) could be an alternative treatment option to implantation of new leads or upgrading of pacemakers to an ICD if vascular access is limited. Here, we assessed the prevalence of S-ICD's eligibility according to surface electrogram screening in those receiving cardiac resynchronization therapy (CRT). S-ICD's eligibility was assessed in patients with a CRT pacemaker or a CRT defibrillator using the S-ICD template screening tool...
September 26, 2018: International Heart Journal
Robbert Zusterzeel, Jose Vicente, Roberto Ochoa-Jimenez, Jun Zhu, Jean-Philippe Couderc, Esther Akinnagbe-Zusterzeel, David G Strauss
The presence of left bundle branch block (LBBB) is an important predictor of benefit from cardiac resynchronization therapy (CRT). New "strict" electrocardiographic (ECG) criteria for LBBB have been shown to better predict benefit from CRT. The "strict" LBBB criteria include: QRS duration ≥140 ms (men) or ≥130 ms (women), QS- or rS-configurations of the QRS complex in leads V1 and V2, and mid-QRS notching or slurring in ≥2 of leads V1, V2, V5, V6, I and aVL. The "strict" LBBB criteria are not regularly used and most hospital automated ECG systems and physicians still use more conventional LBBB criteria...
August 1, 2018: Journal of Electrocardiology
Helder Pereira, Tom A Jackson, Benjamin Sieniewicz, Justin Gould, Cheng Yao, Steven Niederer, Christopher A Rinaldi
BACKGROUND: Cardiac resynchronization therapy (CRT) is now generally delivered via quadripolar leads. Assessment of the effect of different vector programs from quadripolar leads on ventricular activation can be now done using non-invasive electrocardiographic mapping (ECM). MATERIAL AND METHODS: In nineteen patients with quadripolar LV leads, activation maps were constructed. The total ventricular activation time (TVaT) and the time for the bulk of ventricular activation (VaT10-90 ) were calculated...
July 2018: Journal of Electrocardiology
Casper Lund-Andersen, Helen H Petersen, Christian Jøns, Berit T Philbert, Michael Vinther, Jesper H Svendsen
No abstract text is available yet for this article.
July 2018: Journal of Electrocardiology
Sophie Giffard-Roisin, Herve Delingette, Thomas Jackson, Jessica Webb, Lauren Fovargue, Jack Lee, C Aldo Rinaldi, Reza Razavi, Nicholas Ayache, Maxime Sermesant
GOAL: Non-invasive cardiac electrophysiology (EP) model personalisation has raised interest for instance in the scope of predicting EP cardiac resynchronization therapy (CRT) response. However, the restricted clinical applicability of current methods is due in particular to the limitation to simple situations and the important computational cost. METHODS: We propose in this manuscript an approach to tackle these two issues. First, we analyse more complex propagation patterns (multiple onsets and scar tissue) using relevance vector regression and shape dimensionality reduction on a large simulated database...
May 23, 2018: IEEE Transactions on Bio-medical Engineering
Oliver I Brown, Theodora Nikolaidou, Gowan Beddoes, Angela Hoye, Andrew L Clark
GOAL: The HF-CGM is a proof-of-principle study to investigate whether cardiogoniometry (CGM), a three-dimensional electrocardiographic method, can differentiate between pacing modes in patients with cardiac resynchronization therapy (CRT). METHODS: At a tertiary cardiology center, CGM recordings were performed using four pacing modes: no pacing; right ventricular (RV) pacing; left ventricular (LV) pacing, and biventricular (BIV) pacing. Three orthogonal CGM planes orientated to the long axis (XY), the frontal plane (YZ), and the short axis (XZ) of the heart were constructed, and the direction of the QRS-axis was calculated for each pacing mode in each plane...
August 2018: IEEE Transactions on Bio-medical Engineering
Marc Strik, Sylvain Ploux, Peter R Huntjens, Uyên Châu Nguyên, Antionio Frontera, Romain Eschalier, Remi Dubois, Philippe Ritter, Nicholas Klotz, Kevin Vernooy, Michel Haïssaguerre, Harry J G M Crijns, Frits W Prinzen, Pierre Bordachar
BACKGROUND: Electrocardiographic mapping (ECM) expresses electrical substrate through magnitude and direction of the activation delay vector (ADV). We investigated to what extent the response to cardiac resynchronization therapy (CRT) is determined by baseline ADV and by ADV modification through CRT and optimization of left ventricular (LV) pacing site. METHODS: ECM was performed in 79 heart failure patients (4 RBBB, 12 QRS < 120 ms, 23 non-specific conduction delay [NICD] and 40 left bundle branch block [LBBB])...
November 1, 2018: International Journal of Cardiology
Maria A Baturova, Valentina Kutyifa, Scott McNitt, Bronislava Polonsky, Scott Solomon, Jonas Carlson, Wojciech Zareba, Pyotr G Platonov
Cardiac resynchronization therapy (CRT) has proven prognostic benefits in patients with heart failure (HF) with left bundle branch block (LBBB) QRS morphology. Electrocardiographic left atrial (LA) abnormality has been proposed as a noninvasive marker of atrial remodeling. We aimed to assess the impact of electrocardiographic LA abnormality for prognosis in patients with HF treated with CRT. Baseline resting 12-lead electrocardiograms recorded from 941 patients enrolled in the CRT arm of the Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy was processed automatically using Glasgow algorithm, which included automated assessment of P-wave terminal force in lead V1 (PTF-V1 ) as a marker of LA abnormality...
July 15, 2018: American Journal of Cardiology
Marek Jastrzębski, Piotr Kukla, Roksana Kisiel, Kamil Fijorek, Paweł Moskal, Danuta Czarnecka
BACKGROUND: Left bundle branch block (LBBB) is considered an important prognostic parameter in cardiac resynchronization therapy (CRT). We aimed to evaluate, in a sizeable cohort of patients with CRT, long-term mortality, and morbidity according to four different electrocardiographic definitions of LBBB. METHODS: This longitudinal cohort study included consecutive patients who underwent CRT device implantation in our institution in years 2006-2014. Two endpoints were assessed: (a) death from any cause or urgent heart transplantation, and (b) death from any cause or heart failure admission...
September 2018: Annals of Noninvasive Electrocardiology
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