Chi Zhang, Tao Jiang, Guoyong Jiang, Xiang Xu, Chengqi Yan, Yu Kang, Xuejiao Xiang, Shuoyuan Liu, Pengjuan Nie, Maojie Zhang, Jing Chen, Meng Yuan, Yingpeng Xu, Xiaofan Yang, Zhenbing Chen
Small extracellular vesicles (sEVs) from adipose-derived stem cells (ADSCs) have gained great attention and have been widely used in cell-free therapies for treating diabetic non-healing wounds in recent years. However, further clinical application of ADSC-sEVs have been limited due to their unsolvable defects, including cumbersome extraction procedure, high cost, low yield, etc. Thus, we urgently need to find one therapeutic reagent that could not only accelerate diabetic wound healing as ADSC-sEVs but also overcome these shortcomings...
December 2023: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology