Read by QxMD icon Read


Yun-Seong Kang, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Sang-Min Lee
Background: Respiratory failure requiring intubation is a risk factor for mortality in immunocompromised patients, therefore, noninvasive methods to avoid intubation are preferred in such patients. A high-flow nasal cannula (HFNC) is an alternative noninvasive technique for oxygen delivery but can be potentially harmful in cases of delayed intubation. We sought to identify the physiological predictors of outcome to assess the responsiveness to HFNC of immunocompromised patients with acute respiratory failure...
December 2018: Journal of Thoracic Disease
Tetsuro Kamo, Sadatomo Tasaka, Takeshi Suzuki, Takanori Asakura, Shoji Suzuki, Kazuma Yagi, Ho Namkoong, Makoto Ishii, Hiroshi Morisaki, Tomoko Betsuyaku
BACKGROUND: In the Berlin definition, acute respiratory distress syndrome (ARDS) is stratified into three stages according to oxygenation severity at the onset. The relevance between ARDS severity and prognosis varies among published reports and has not been verified, especially in Asian patients. METHODS: In this study, we examined the associations between the Berlin definition criteria and prognosis and clinical parameters, including high-resolution computed tomography (HRCT) scores of fibroproliferative changes of the lungs...
February 11, 2019: BMC Pulmonary Medicine
Kai-Yin Hung, Yu-Mu Chen, Chin-Chou Wang, Yi-Hsi Wang, Chiung-Yu Lin, Ya-Ting Chang, Kuo-Tung Huang, Meng-Chih Lin, Wen-Feng Fang
Immune dysfunction is seen both in sepsis patients and in those with malnutrition. This study aimed to determine whether insufficient nutrition and immune dysfunction have a synergistic effect on mortality in critically ill septic patients. We conducted a prospective observational study from adult sepsis patients admitted to intensive care units (ICUs) between August 2013 and June 2016. Baseline characteristics including age, gender, body mass index, NUTRIC, Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores were recorded...
February 10, 2019: Nutrients
Antônio Luis Eiras Falcão, Alexandre Guimarães de Almeida Barros, Angela Alcântara Magnani Bezerra, Natália Lopes Ferreira, Claudinéia Muterle Logato, Filipa Pais Silva, Ana Beatriz Francioso Oliveira do Monte, Rodrigo Marques Tonella, Luciana Castilho de Figueiredo, Rui Moreno, Desanka Dragosavac, Nelson Adami Andreollo
BACKGROUND: The early postoperative period is critical for surgical patients. SOFA, SAPS 3 and APACHE II are prognostic scores widely used to predict mortality in ICU patients. This study aimed to evaluate these index tests for their prognostic accuracy for intra-ICU and in-hospital mortalities as target conditions in patients admitted to ICU after urgent or elective surgeries and to test whether they aid in decision-making. The process comprised the assessment of discrimination through analysis of the areas under the receiver operating characteristic curves and calibration of the prognostic models for the target conditions...
January 30, 2019: Annals of Intensive Care
Burak Ülkümen, Görkem Eskiizmir, Demet Tok, Melek Çivi, Onur Çelik
Objective: Open surgical tracheotomy (OST) and percutaneous dilatational tracheotomy (PDT) are commonly used for securing airway in intubated critically ill patients. The purpose of this study was to compare the safety of OST and PDT, particularly in intubated critically ill patients. Methods: The medical records of intubated critically ill patients who underwent tracheotomy between August 2006 and July 2017 were analyzed retrospectively. Minor and major complication rates were compared according to the tracheotomy technique...
December 2018: Turkish Archives of Otorhinolaryngology
Mariusz Piechota, Anna Piechota, Małgorzata Misztal, Szymon Bernas, Iwona Pietraszek-Grzywaczewska
Introduction: The mortality rate in patients with severe liver dysfunction with no option of transplantation is unacceptably high. The main aim of this study was to evaluate the usefulness of applying extracorporeal liver support (ECLS) techniques in this group of patients. Material and methods: Data from hospital admissions of 101 patients with severe liver dysfunction who were admitted to the department of Anaesthesiology and intensive therapy between 2006 and 2015 were retrospectively analysed...
January 2019: Archives of Medical Science: AMS
Tatyanne Ln Gomes, Renata C Fernandes, Liana L Vieira, Raquel M Schincaglia, João F Mota, Marciano S Nóbrega, Claude Pichard, Gustavo D Pimentel
OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care unit (ICU) has not been fully elucidated. The aim of this study was to investigate whether the serum concentrations of 25-hydroxyvitamin D (25[OH]D) within the first 48 h after ICU admission are associated with prognostic indicators (Acute Physiology and Chronic Health Evaluation [APACHE] II, Sequential Organ Failure Assessment [SOFA] score, Charlson comorbidity index [CCI]), clinical complications, serum C-reactive protein (CRP) concentrations, mechanical ventilation duration, and mortality...
October 24, 2018: Nutrition
Keertana Badrinath, Monica Shekhar, Moturu Sreelakshmi, Meenakshi Srinivasan, Girish Thunga, Sreedharan Nair, Karthik Rao Nileshwar, Athira Balakrishnan, Vijayanarayana Kunhikatta
Background: Sepsis is a complex condition defined by the systemic response to infection. Severity assessment scoring systems are used to aid the physician in deciding whether aggressive treatment is needed or not. In this study, various severity assessment scoring systems, namely Acute Physiology and Chronic Health Evaluation II (APACHE II), Rapid Emergency Medicine Score (REMS), Sequential Organ Failure Assessment (SOFA), Multiple Organ Dysfunction Score (MODS), Predisposition, Infection, Response, and Organ Dysfunction (PIRO), and Mortality in Emergency Department Sepsis (MEDS), were compared to assess their sensitivity and specificity...
December 2018: Indian Journal of Critical Care Medicine
Michael Chourdakis, Maria G Grammatikopoulou, Kalliopi Anna Poulia, Marili Passakiotou, Zoe K Pafili, Emmanouil Bouras, Ioannis Doundoulakis, Ioannis Galitsianos, Theodora Lappa, Anestis Karakatsanis, Daren K Heyland
BACKGROUND & AIMS: Patients in the intensive care unit are experiencing an increased malnutrition risk. The NUTrition Risk in the Critically ill score (NUTRIC) is a validated tool for the identification of patients that will benefit the most, from nutritional intervention. The aim of the study was twofold, including: 1) to translate and adapt the NUTRIC score in the Greek language for more efficient and comprehensive use among clinicians, and 2) to assess its prognostic performance in a pilot sample...
February 2019: Clinical Nutrition ESPEN
Rahul Kashyap, Tarun D Singh, Hamza Rayes, John C O'Horo, Gregory Wilson, Philippe Bauer, Ognjen Gajic
PURPOSE: The newly proposed septic shock definition has provoked a substantial controversy in the emergency and critical care communities. We aim to compare new (SEPSIS-III) versus old (SEPSIS-II) definitions for septic shock in a contemporary cohort of critically ill patients. MATERIAL AND METHODS: Retrospective cohort of consecutive patients, age ≥ 18 years admitted to intensive care units at the Mayo Clinic between January 2009 and October 2015. We compared patients who met old, new, both, or neither definition of sepsis shock...
January 11, 2019: Journal of Critical Care
Joana Silvestre, Luis Coelho, João Gonçalves Pereira, Vitor Mendes, Camila Tapadinhas, Pedro Póvoa
OBJECTIVE: To determine the performance of soluble urokinase-type plasminogen activator receptor upon intensive care unit discharge to predict post intensive care unit mortality. METHODS: A prospective observational cohort study was conducted during a 24-month period in an 8-bed polyvalent intensive care unit. APACHE II, SOFA, C-reactive protein, white cell count and soluble urokinase-type plasminogen activator receptor on the day of intensive care unit discharge were collected from patients who survived intensive care unit admission...
January 10, 2019: Revista Brasileira de Terapia Intensiva
Dimitrios Velissaris, Nikolaos-Dimitrios Pantzaris, Anastasia Skroumpelou, Panagiotis Polychronopoulos, Vasilios Karamouzos, Charalampos Pierrakos, Charalampos Gogos, Menelaos Karanikolas
Objective: To evaluate the electroencephalographic (EEG) findings and correlate EEG findings with inflammatory biomarkers and the sepsis prognostic scores SOFA, SAPS II and APACHE II in patients who present in the Emergency Department with sepsis without clinical central nervous system involvement. Methods: The study included seventeen patients (< 70 years old) with sepsis without central nervous system involvement presenting in the Emergency Department of the University Hospital of Patras, Greece...
December 2018: Journal of Translational Internal Medicine
Mahesh Balakrishnan, Hemang Gandhi, Komal Shah, Himani Pandya, Ramesh Patel, Sunny Keshwani, Nikhil Yadav
Background and Aims: The effect of vitamin C on vasopressor requirement in critically ill patients have been evaluated previously. We aimed to evaluate the effect of vitamin C, hydrocortisone and thiamine on vasopressor requirement and mortality in post-operative adult cardiac surgical patients with septic shock. Methods: About 24 patients with septic shock were randomised into Group 1 (receiving matching placebo per day for 4 days) and Group 2 (receiving 6 g vitamin C, 400 mg thiamine and 200 mg hydrocortisone per day for 4 days)...
December 2018: Indian Journal of Anaesthesia
Ansony R Godinez-Vidal, Hirosi Sashida-Méndez, Christian I Cruz-Romero, Hamzeh Bandeh-Moghaddam, Carlos A Gutiérrez-Banda, Noe I Gracida-Mancilla
Introducción: La apendicitis aguda (AA) es una de las principales causas de abdomen agudo. Un retraso en su diagnóstico y tratamiento elevan la morbimortalidad. Objetivo: Evaluar el índice de neutrófilos/linfocitos (INL), la escala SOFA (Sequential Organ Failure Assessment), la procalcitonina (PCT) y la bilirrubina total (BT), y ver si existe relación como determinantes de la gravedad de la AA. Método: Estudio retrospectivo, observacional, para comparar el INL contra biomarcadores (PCT, BT) y contra escalas de gravedad (APACHE II [Acute Physiology and Chronic Health Evaluation] y SOFA) y quirúrgica (Mannheim)...
2019: Cirugia y Cirujanos
Maria Cristina Gonzalez, Renata M Bielemann, Paula P Kruschardt, Silvana P Orlandi
AIMS: To compare the prognostic power of nutritional screening (NUTRIC score) and Subjective Global Assessment (SGA), executed alone or their complementarity, for predicting 28-day mortality risk in ICU patients. We also aimed to identify the cut-off point obtained in the NUTRIC that presented the best validity parameters for predicting mortality in this population. METHODS: A sample of 159 patients was evaluated in the first 24 hours of ICU admission. Modified NUTRIC score was performed (without interleucina-6)...
December 18, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Shuo Wang, Binghou Yang, Xiang Li, Yufei Sun, Shuguang Cao, Tianhua Zhu, Minjun Xu, Xueyin Li, Tianyu Li, Junxiang Zhao
OBJECTIVE: To retrospectively analyze the injury characteristics of victims and treatment strategies in the explosion accident on the 17th May 2018 in Xixia county (Xixia "May 17th" explosion accident). METHODS: Completion the Level Three treatment on time, which was depended on the leading role played by the regional trauma centers was the main rescuing mode of the work in Xixia county, where the primary and secondary treatments were the key parts. The three-level treatment model includes: the local hospital acts as a level-one emergency medical institution, county hospitals function as secondary emergency medical institutions, and other higher medical institutions are the tertiary first aid medical institutions...
December 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Aiping Wu, Jinzhu Wang, Fang Han, Yin Ni
OBJECTIVE: To discuss the correlation between shock index (SI) and severity and the values to forecast the prognosis in patients with septic shock. METHODS: 127 patients with septic shock admitted to intensive care unit (ICU) of Zhejiang Provincial People's Hospital from January 1st, 2016 to October 31st, 2017 were enrolled, and they were divided into survival group and death group according to the outcomes after 28-day hospitalized. The vital signs, laboratory indexes, acute physiology and chronic health evaluation II (APACHE II), sequential organ failure assessment (SOFA), lactate clearance rate (LCR) of 3 hours after fluid resuscitation, and shock index on admission (SI1 ) and shock index of 3 hours after fluid resuscitation (SI2 ) were compared between the two groups...
December 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Weizhi Liang, Can Chen, Li Li, Hong Xu, Zhenhui Guo, Wenjie Huang
OBJECTIVE: To investigate the influence of immune function and its changes on the prognosis of patients with sepsis. METHODS: 393 patients who met the diagnostic criteria of Sepsis-3 admitted to General Hospital of Southern War Zone of PLA from April 2003 to April 2017 were enrolled. Clinical data were collected and analyzed retrospectively. According to the initial immune status, patients with more than 4 days course of disease were divided into the initial immune suppression group (219 cases) and the initial immune function normal group (174 cases)...
December 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Saskia Semmlack, Peter W Kaplan, Rainer Spiegel, Gian Marco De Marchis, Sabina Hunziker, Kai Tisljar, Stephan Rüegg, Stephan Marsch, Raoul Sutter
OBJECTIVE: To characterize a critically ill cohort with status epilepticus (SE) by the illness severity scoring systems SAPS II (Simplified Acute Physiology Score II), APACHE II (Acute Physiology and Chronic Health Evaluation II), and SOFA (Sequential Organ Failure Assessment), and to compare their performance with the STESS (Status Epilepticus Severity Score) for outcome prediction. METHODS: The prospective cohort study was carried out at the University Hospital Basel, a Swiss tertiary academic medical care center...
December 25, 2018: Epilepsia
Valliappan Muthu, Ritesh Agarwal, Sahajal Dhooria, Kuruswamy Thurai Prasad, Ashutosh N Aggarwal, Vanita Suri, Inderpaul Singh Sehgal
PURPOSE: We describe the epidemiology, lung mechanics and outcomes of acute respiratory distress syndrome (ARDS) complicating pregnancy. We also compare the outcomes of ARDS in pregnant and non-pregnant females. METHODS: Retrospective observational study of all women admitted with ARDS. RESULTS: 211 women with ARDS were admitted, which included 27 (12.8%) pregnant subjects. All were ventilated with a low tidal volume strategy. Most pregnant females presented during the third trimester...
December 7, 2018: Journal of Critical Care
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"