keyword
https://read.qxmd.com/read/38530798/in-patients-supported-with-peripheral-veno-arterial-extracorporeal-membrane-oxygenation-what-factors-are-associated-with-the-development-of-spinal-cord-ischaemia
#21
JOURNAL ARTICLE
Alison Zhu, Charis Tan, Richard Chard, Yishay Orr
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was in patients supported with peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO), what factors are associated with the development of spinal cord ischaemia? Altogether more than 22 papers were found using the reported search, of which 10 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated...
March 26, 2024: Interdiscip Cardiovasc Thorac Surg
https://read.qxmd.com/read/38530681/trends-in-substance-related-visits-among-youth-to-us-children-s-hospitals-2016-2021-an-analysis-of-the-pediatric-health-information-system-database
#22
JOURNAL ARTICLE
Alexis Ball, Scott Hadland, Jonathan Rodean, Matt Hall, Jason Mendoza, Kym Ahrens
PURPOSE: This study evaluates recent trends in substance-related visits among youth visiting children's hospitals. METHODS: We conducted a cross-sectional study of substance-related visits to pediatric hospitals within the Pediatric Health Information System database of youth aged 12-21 years from 2016 through 2021. Substance-related visits were defined as acute visits for International Classification of Diseases, 10th Revision Clinical Modification codes related to substance 'use', dependence, or overdoses for alcohol, cannabis, nicotine, opioids, sedatives, stimulants, hallucinogens, or other substances...
March 25, 2024: Journal of Adolescent Health
https://read.qxmd.com/read/38530642/ciprofol-alleviates-remifentanil-induced-hyperalgesia-by-regulating-%C3%AE-2gabaars-nr2b-and-p-camkii%C3%AE-levels-in-the-spinal-cord-and-hippocampus
#23
JOURNAL ARTICLE
Yang Yang, Chao Yang, Yujie Shi, Chengyuan Tang, Hanyu Wang, Mengyuan Tan, Ruyi Xing, Chen Gao, Min Zhang, Yanhu Xie
OBJECTIVES: Several studies have shown that propofol administration during surgery effectively attenuates remifentanil-induced hyperalgesia (RIH). Ciprofol, a novel intravenous sedative agent analogous to propofol, has not yet been proven efficacious in alleviating RIH. The present study aimed to investigate the effect of ciprofol on RIH and the possible mechanisms involved. METHODS: The RIH model was established by an infusion of remifentanil (1 μg·kg-1·min-1) 60 min in rats with incisional pain...
March 26, 2024: Journal of Pharmacy and Pharmacology
https://read.qxmd.com/read/38530502/the-evaluation-of-a-non-invasive-respiratory-monitor-in-ards-patients-in-supine-and-prone-position
#24
JOURNAL ARTICLE
Tommaso Pozzi, Silvia Coppola, Elena Chiodaroli, Federico Cucinotta, Francesca Becci, Davide Chiumello
PURPOSE: The Prone positioning in addition to non invasive respiratory support is commonly used in patients with acute respiratory failure. The aim of this study was to assess the accuracy of an impedance-based non-invasive respiratory volume monitor (RVM) in supine and in prone position. METHODS: In sedated, paralyzed and mechanically ventilated patients in volume-controlled mode with acute respiratory distress syndrome scheduled for prone positioning it was measured and compared non-invasively tidal volume and respiratory rate provided by the RVM in supine and, subsequently, in prone position, by maintaining unchanged the ventilatory setting...
March 26, 2024: Journal of Clinical Monitoring and Computing
https://read.qxmd.com/read/38529825/diamond-burr-debridement-of-calcific-band-keratopathy-in-24-eyes-of-22-horses
#25
JOURNAL ARTICLE
Sophie Jugant, Alain Regnier, Jean-Yves Douet
PURPOSE: To evaluate the safety and effectiveness of diamond burr debridement (DBD) for the treatment of calcific band keratopathy (CBK) in horses. METHODS: Medical records from horses with CBK were reviewed over a period of 4 years. Diagnosis of CBK was based on slit-lamp examination findings, and DBD was performed on standing sedated horses. Follow-up was obtained by clinical reevaluation of the treated eyes or a telephone survey with the referring veterinarian...
March 26, 2024: Veterinary Ophthalmology
https://read.qxmd.com/read/38529461/analysis-of-sedation-accident-records-available-in-the-japan-council-for-quality-health-care-public-database
#26
JOURNAL ARTICLE
Uno Imaizumi, Hidetaka Kuroda, Shota Tsukimoto, Norika Katagiri, Takuro Sanuki
OBJECTIVE: Medical accidents occur frequently. However, only a few studies have been conducted on sedation-related medical accidents. This study aimed to classify sedation accidents and analyze their causes using the (Patient-management Software Hardware Environment Livewear (P-mSHELL) model. METHODS: The Japan Council for Quality Health Care database on medical accidents was used. Sedation accidents that occurred during procedures between January 2010 and June 2022 were included...
February 2024: Curēus
https://read.qxmd.com/read/38529445/rectal-sedation-with-ketamine-and-midazolam-in-the-management-of-uncooperative-children-during-dental-treatment-a-case-series-and-method-description
#27
JOURNAL ARTICLE
Hasan Alzoubi, Samar Kabbani, Ahmad Taleb, Nada Bshara, Mohamed K Altinawi, Mohammed Bashier Almonakel, Saleh Al Kurdi
Background In pediatric dentistry, sedation aims to eliminate anxiety to facilitate the completion of dental procedures. Sedation in children is a multidimensional field that includes the child, parents/guardians, and the health care team. The rectal route is generally painless, making it suitable for children who are afraid of needles. This route has several advantages over the oral route, including reduced patient cooperation requirements, a faster and more predictable onset, and less physical trauma than the intravenous and intramuscular routes...
February 2024: Curēus
https://read.qxmd.com/read/38528812/gut-microbiota-and-symptom-expression-and-severity-in-neonatal-abstinence-syndrome
#28
JOURNAL ARTICLE
Stephanie Sealschott, Rita Pickler, Christine Fortney, Michael Bailey, Brett Loman
Problem: Neonatal abstinence syndrome (NAS) affecting neonates with fetal exposure to opioids, is defined by expression and severity of symptoms. The pathophysiology behind symptoms variability is lacking. The study aims were to examine (a) differences in gut microbiota of neonates with and without NAS, (b) the relationships between gut microbiota and symptom expression and NAS severity, and (c) the changes in the neonate gut microbiota diversity during the course of NAS treatment. Methods: A cross-sectional observational design was used to examine differences in microbiota and a longitudinal, repeated measures approach was used to determine relationships between gut microbiota and NAS symptoms...
March 26, 2024: Biological Research for Nursing
https://read.qxmd.com/read/38528133/does-acute-cannabidiol-cbd-use-impair-performance-a-meta-analysis-and-comparison-with-placebo-and-delta-9-tetrahydrocannabinol-thc
#29
JOURNAL ARTICLE
Lindsay A Lo, April L Christiansen, Justin C Strickland, Carly A Pistawka, Lauren Eadie, Ryan Vandrey, Caroline A MacCallum
Cannabidiol (CBD) is widely used and believed to be non-intoxicating, lacking acute performance effects (e.g., non-impairing). However, a synthesis of data has not evaluated this. This meta-analysis synthesized data from controlled human laboratory studies that evaluated if acute CBD use impairs performance. Performance on objective and subjective measures of cognitive and psychomotor function were used as markers for potential performance changes and impairment. Studies were identified through systematic database searches...
March 25, 2024: Neuropsychopharmacology
https://read.qxmd.com/read/38528026/pharmacokinetic-and-pharmacodynamic-evaluation-study-of-etomidate-a-randomized-open-label-2-period-crossover-study-in-healthy-chinese-subjects
#30
JOURNAL ARTICLE
Ying Ding, Nan-Nan Chu, Rui Wang, Wei Qin, Yun-Fei Shi, Zhen-Zhong Qian, Bo Liu, Qing He
Etomidate is a sedative and hypnotic drug through intravenous administration that act on the central nervous system through GABA (Gamma-Amino Butyric Acid) receptors, which is widely used in anesthesia induction and maintenance and long-term sedation in severe patients. The study aimed to evaluate the pharmacokinetic and pharmacodynamic properties of two etomidate fat emulsions after administration through the intravenous infusion pump in healthy Chinese subjects. A randomized, open-label, 2-period crossover study was performed in 52 healthy subjects...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38527071/incidence-of-oncogenic-hpv-infection-in-women-with-and-without-mental-illness-a-population-based-cohort-study-in-sweden
#31
JOURNAL ARTICLE
Eva Herweijer, Kejia Hu, Jiangrong Wang, Donghao Lu, Pär Sparén, Hans-Olov Adami, Unnur Valdimarsdóttir, Karin Sundström, Fang Fang
BACKGROUND: Women with mental illness experience an increased risk of cervical cancer. The excess risk is partly due to low participation in cervical screening; however, it remains unknown whether it is also attributable to an increased risk of infection with human papillomavirus (HPV). We aimed to examine whether women with mental illness had an increased infection rate of HPV compared to women without mental illness. METHODS AND FINDINGS: Using a cohort design, we analyzed all 337,116 women aged 30 to 64 and living in Stockholm, who had a negative test result of 14 high-risk HPV subtypes in HPV-based screening, during August 2014 to December 2019...
March 25, 2024: PLoS Medicine
https://read.qxmd.com/read/38526920/nerolidol-reduces-depression-like-behavior-in-mice-and-suppresses-microglia-activation-by-down-regulating-dna-methyltransferase-1
#32
JOURNAL ARTICLE
Guangcai Zhang, Xiaohui Zhou, Qifan Feng, Weihua Ke, Jiahui Pan, Haiying Zhang, Yixian Luan, Beibei Lei
Modern medicine has unveiled that essential oil made from Aquilaria possesses sedative and hypnotic effects. Among the chemical components in Aquilaria, nerolidol, a natural sesquiterpene alcohol, has shown promising effects. This study aimed to unravel the potential of nerolidol in treating depression. Chronic unpredictable mild stress (CUMS) was utilized to induce depression-like behavior in mice, and open field test, sucrose preference, and tail suspension test was conducted. The impacts of nerolidol on the inflammatory response, microglial activation, and DNA methyltransferase 1 (DNMT1) were assessed...
March 15, 2024: Neuroreport
https://read.qxmd.com/read/38526060/a-proof-of-concept-study-evaluating-cardiac-compression-techniques-for-cardiopulmonary-resuscitation-in-laying-hens-gallus-gallus
#33
JOURNAL ARTICLE
Jessica Eisenbarth, Charles O Cummings, Elizabeth A Rozanski, Emily Karlin, John Rush
OBJECTIVE: To determine in adult chickens which of 3 CPR techniques, sternal compressions (SC), SC with interposed caudal coelomic compressions (ICCC), or lateral compressions (LC), results in the highest mean systolic (SAP), diastolic (DAP), and mean arterial pressure (MAP) as measured directly from the carotid artery. DESIGN: Prospective, nonblinded, experimental crossover study. SETTING: University teaching hospital laboratory. ANIMALS: Ten retired laying hens...
March 25, 2024: Journal of Veterinary Emergency and Critical Care
https://read.qxmd.com/read/38525870/clinical-outcomes-associated-with-orphenadrine-deliberate-self-poisoning-a-retrospective-poisons-centre-study
#34
JOURNAL ARTICLE
Nina Dhaliwal, Darren M Roberts
INTRODUCTION: Orphenadrine overdoses can cause antimuscarinic toxicity, respiratory failure, refractory seizures and cardiotoxicity. The dose-toxicity relationship is poorly defined. Orphenadrine is marketed as immediate and sustained release formulations, and it is not known how the formulation impacts on toxicity. We determined the clinical toxicity of orphenadrine in patients referred to a regional poisons centre. METHODS: Retrospective case series of patients in New South Wales with orphenadrine deliberate self-poisoning from January 2016 to April 2022 referred to the New South Wales Poisons Information Centre...
March 25, 2024: Clinical Toxicology
https://read.qxmd.com/read/38525223/development-of-a-method-for-the-determination-of-sedatives-in-bovine-and-porcine-urine-and-kidneys-by-liquid-chromatography-tandem-mass-spectrometry
#35
JOURNAL ARTICLE
Tomasz Śniegocki, Elżbieta Samorek, Bartosz Sell, Weronika Krajewska
INTRODUCTION: Sedatives have been used for a long time as animal tranquillisers to prevent stress and weight loss during their transportation. The proper determination of these substances in food of animal origin is essential for consumer safety. MATERIAL AND METHODS: A 1 g portion of pig or cow urine or homogenised kidney was mixed with acetonitrile, sodium chloride was added, and the solution was further mixed and then centrifuged. The supernatant was transferred to a new centrifuge tube with primary and secondary amine, octadecylsilane and ZrO2 , and mixed rapidly...
March 2024: Journal of Veterinary Research
https://read.qxmd.com/read/38524515/significant-risk-factors-for-intensive-care-unit-acquired-weakness-a-processing-strategy-based-on-repeated-machine-learning
#36
JOURNAL ARTICLE
Ling Wang, Deng-Yan Long
BACKGROUND: Intensive care unit-acquired weakness (ICU-AW) is a common complication that significantly impacts the patient's recovery process, even leading to adverse outcomes. Currently, there is a lack of effective preventive measures. AIM: To identify significant risk factors for ICU-AW through iterative machine learning techniques and offer recommendations for its prevention and treatment. METHODS: Patients were categorized into ICU-AW and non-ICU-AW groups on the 14th day post-ICU admission...
March 6, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38524507/safety-and-efficacy-comparison-of-remimazolam-and-propofol-for-intravenous-anesthesia-during-gastroenteroscopic-surgery-of-older-patients-a-meta-analysis
#37
JOURNAL ARTICLE
Fang-Zhuo Li, Cheng Zhao, Yi-Xun Tang, Ji-Tong Liu
BACKGROUND: Remimazolam is characterized by rapid action and inactive metabolites. It is used as the general anesthetic for many clinical surgeries. In this study, we performed a meta-analysis to evaluate whether remimazolam is superior to propofol for gastroenteroscopy in older patients. AIM: To compare the adverse events and efficacy of remimazolam and propofol during gastroenteroscopy in older adults. METHODS: The PubMed, Web of Science, the Cochrane Library databases were queried for the relevant key words "remimazolam," "and propofol," "and gastrointestinal endoscopy or gastroscopy...
March 6, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38524272/factors-associated-with-insomnia-and-fatigue-symptoms-during-the-outbreak-of-oct-7th-war-on-gaza-a-study-from-jordan
#38
JOURNAL ARTICLE
Omar Salem Gammoh, Abdelrahim Alqudah, Bardiah Alotaibi
OBJECTIVE: The Jordanian and the Palestinian communities are tightly related, hence, the current war on Gaza also has social and psychological impacts on Jordanians. Therefore, this study aims to identify the factors associated with severe insomnia and fatigue symptoms in a cohort of Jordanians during the Gaza War outbreak. METHODS: This is a cross-sectional web-based questionnaire study. The Insomnia Severity Index-Arabic version (ISI-A), and the Brief Fatigue Inventory-Arabic (BFI-A) were employed, binary logistic and linear regression analyses was performed to identify predictors to severe insomnia and fatigue respectively...
May 2024: Preventive Medicine Reports
https://read.qxmd.com/read/38524064/nebulized-versus-intravenously-administered-dexmedetomidine-for-obtunding-hemodynamic-responses-to-laryngoscopy-and-tracheal-intubation-a-randomized-double-blind-comparative-study
#39
JOURNAL ARTICLE
Akshita Singla, Rajkumar K Saraswat, Avnish Bharadwaj, Sapna Singh
Introduction Intravenous dexmedetomidine is known to cause major adverse effects such as bradycardia, hypotension, cardiac arrhythmias, and heart block when used as premedication for attenuation of the laryngoscopy and intubation response, limiting its routine use. Thus, it is important to study other routes of administration of dexmedetomidine. Objectives To compare the hemodynamic response and sedation score between intravenous and nebulized dexmedetomidine as premedication for the attenuation of the laryngoscopy and intubation response...
February 2024: Curēus
https://read.qxmd.com/read/38524059/ultrasound-guided-selective-glossopharyngeal-nerve-block-for-severe-gag-reflex-during-dental-treatment-a-report-of-two-cases
#40
Yuki Kojima, Daisuke Oiwa
The ultrasound-guided selective glossopharyngeal nerve block (UGSGNB) has been developed as an approach to overcome the drawbacks of the conventional glossopharyngeal nerve block. The UGSGNB may be performed when a gag reflex occurs during dental treatment. Case 1 involved a 67-year-old man with a medical history of cervical spondylosis and dilated cardiomyopathy. Dental treatment with conscious sedation and the UGSGNB was performed three times. Case 2 involved a 25-year-old woman who was scheduled for dental treatment under general anesthesia because of dental phobia and gagging...
February 2024: Curēus
keyword
keyword
160359
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.