S E Novikova, T V Tolstova, N A Soloveva, T E Farafonova, O V Tikhonova, L K Kurbatov, A L Rusanov, V G Zgoda
Plasma membrane proteins with extracellular-exposed domains are responsible for transduction of extracellular signals into intracellular responses, and their accessibility to therapeutic molecules makes them attractive targets for drug development. In this work, using omics technologies and immunochemical methods, we have studied changes in the content of markers of clusters of differentiation (CD markers) of neutrophils (CD33, CD97, CD54, CD38, CD18, CD11b, CD44, and CD71) at the level of transcripts and proteins in NB4, HL-60 and K562 cell lines, induced by the treatment with all-trans-retinoic acid (ATRA)...
December 2023: Biomedit︠s︡inskai︠a︡ Khimii︠a︡