keyword
https://read.qxmd.com/read/38470343/continuous-multi-column-capture-of-monoclonal-antibodies-with-convective-diffusive-membrane-adsorbers
#21
JOURNAL ARTICLE
Fabian Schmitz, Elias Knöchelmann, Thomas Kruse, Mirjana Minceva, Markus Kampmann
Downstream processing is the bottleneck in the continuous manufacturing of monoclonal antibodies (mAbs). To overcome throughput limitations, two different continuous processes with a novel convective diffusive protein A membrane adsorber (MA) were investigated: the rapid cycling parallel multi-column chromatography (RC-PMCC) process and the rapid cycling simulated moving bed (RC-BioSMB) process. First, breakthrough curve experiments were performed to investigate the influence of the flow rate on the mAb dynamic binding capacity and to calculate the duration of the loading steps...
March 12, 2024: Biotechnology and Bioengineering
https://read.qxmd.com/read/38467364/insight-into-key-interactions-between-diverse-factors-and-membrane-fouling-mitigation-in-anaerobic-membrane-bioreactor
#22
REVIEW
Lu Liu, Yihe Wang, Yongxiao Liu, Jinghui Wang, Chengzhi Zheng, Wei Zuo, Yu Tian, Jun Zhang
Anaerobic membrane bioreactors (AnMBRs) have garnered considerable attention as a low-energy and low-carbon footprint treatment technology. With an increasing number of scholars focusing on AnMBR research, its outstanding performance in the field of water treatment has gradually become evident. However, the primary obstacle to the widespread application of AnMBR technology lies in membrane fouling, which leads to reduced membrane flux and increased energy demand. To ensure the efficient and long-term operation of AnMBRs, effective control of membrane fouling is imperative...
March 9, 2024: Environmental Pollution
https://read.qxmd.com/read/38457889/biochar-mediated-high-rate-anaerobic-bioreactors-a-critical-review-on-high-strength-wastewater-treatment-and-management
#23
REVIEW
Kunwar Paritosh, Nupur Kesharwani
Treatment of high-strength wastewater is critical for the aquatic environment and receiving water bodies around the globe. Untreated or partially treated high-strength wastewater may cause severe damage to the existing water bodies. Various high-rate anaerobic bioreactors have been developed in the last decades for treating high-strength wastewater. High-rate anaerobic bioreactors are effective in treating industrial wastewater and provide energy in the form of methane as well. However, the physical or chemical properties of high-strength industrial wastewater, sometimes, disrupt the functioning of a high-rate anaerobic bioreactor...
March 7, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38452912/a-comprehensive-review-and-perspective-research-in-technology-integration-for-the-treatment-of-gaseous-volatile-organic-compounds
#24
REVIEW
Divya Baskaran, Duraisami Dhamodharan, Uma Sankar Behera, Hun-Soo Byun
Volatile organic compounds (VOCs) are harmful pollutants emitted from industrial processes. They pose a risk to human health and ecosystems, even at low concentrations. Controlling VOCs is crucial for good air quality. This review aims to provide a comprehensive understanding of the various methods used for controlling VOC abatement. The advancement of mono-functional treatment techniques, including recovery such as absorption, adsorption, condensation, and membrane separation, and destruction-based methods such as natural degradation methods, advanced oxidation processes, and reduction methods were discussed...
March 5, 2024: Environmental Research
https://read.qxmd.com/read/38450621/optimum-quorum-quenching-bacteria-concentration-in-the-better-quality-cell-entrapping-beads-to-control-biofouling-in-membrane-bioreactor
#25
JOURNAL ARTICLE
Jennifer Rose, Shinho Chung, Zia Ul Islam, Bushra Azhar, Heekyong Oh
Quorum quenching (QQ) by cell entrapping beads (CEBs) is known to inhibit biofouling by its biological and physical cleaning effect. Although there are better QQ media reported, due to the ease of fabrication of QQ-CEBs, this study focused on improving the quality of CEBs by comparing two distinct bead-making methods - polyvinyl alcohol-alginate (PVA-alginate) and phase inversion - and on finding the optimum concentration of QQ bacteria in the CEBs. The evaluation of PVA-alginate bead showed better uniformity, and higher mechanical and chemical strength in comparison with the phase inversion bead...
March 7, 2024: Biofouling
https://read.qxmd.com/read/38447377/dissolved-organic-nitrogen-is-a-key-to-improving-the-biological-treatment-potential-of-landfill-leachate
#26
JOURNAL ARTICLE
Qi Chen, Fan Lü, Hua Zhang, Ying Han, Pinjing He
Biological treatment is one of the most promising efficient, low-carbon and affordable approaches for the treatment of recalcitrantly degradable wastewater, such as landfill leachate. However, even the macroscopic molecular level analysis of dissolved organic matter (DOM) is limiting to the enhancement of biological treatment efficacy, and there is an urgent need for deeper exploration of DOM to gain insights into the key constraining substances. In the present study targeting at piercing leachate organic at molecular level, nitrogen-containing dissolved organic matter (DOMN ) was identified to be the bottleneck that govern the biotreatment potential...
February 29, 2024: Water Research
https://read.qxmd.com/read/38435819/development-of-a-multifunctional-bioreactor-to-evaluate-the-promotion-effects-of-cyclic-stretching-and-electrical-stimulation-on-muscle-differentiation
#27
JOURNAL ARTICLE
Wei-Wen Hu, Yen-Chi Chen, Chia-Wen Tsao, Shen-Liang Chen, Chung-Yuh Tzeng
A multifunctional bioreactor was fabricated in this study to investigate the facilitation efficiency of electrical and mechanical stimulations on myogenic differentiation. This bioreactor consisted of a highly stretchable conductive membrane prepared by depositing polypyrrole (PPy) on a flexible polydimethylsiloxane (PDMS) film. The tensile deformation of the PPy/PDMS membrane can be tuned by adjusting the channel depth. In addition, PPy/PDMS maintained its electrical conductivity under continuous cyclic stretching in the strain range of 6...
March 2024: Bioengineering & Translational Medicine
https://read.qxmd.com/read/38413399/production-of-recombinant-vesicular-stomatitis-virus-based-vectors-by-tangential-flow-depth-filtration
#28
JOURNAL ARTICLE
Sven Göbel, Lars Pelz, Cristina A T Silva, Béla Brühlmann, Charles Hill, Jennifer Altomonte, Amine Kamen, Udo Reichl, Yvonne Genzel
Cell culture-based production of vector-based vaccines and virotherapeutics is of increasing interest. The vectors used not only retain their ability to infect cells but also induce robust immune responses. Using two recombinant vesicular stomatitis virus (rVSV)-based constructs, we performed a proof-of-concept study regarding an integrated closed single-use perfusion system that allows continuous virus harvesting and clarification. Using suspension BHK-21 cells and a fusogenic oncolytic hybrid of vesicular stomatitis virus and Newcastle disease virus (rVSV-NDV), a modified alternating tangential flow device (mATF) or tangential flow depth filtration (TFDF) systems were used for cell retention...
February 27, 2024: Applied Microbiology and Biotechnology
https://read.qxmd.com/read/38412252/iron-oxide-nanoparticles-engineered-macrophage-derived-exosomes-for-targeted-pathological-angiogenesis-therapy
#29
JOURNAL ARTICLE
Haorui Zhang, Yu Mao, Zheng Nie, Qing Li, Mengzhu Wang, Chang Cai, Weiju Hao, Xi Shen, Ning Gu, Wei Shen, Hongyuan Song
Engineering exosomes with nanomaterials usually leads to the damage of exosomal membrane and bioactive molecules. Here, pathological angiogenesis targeting exosomes with magnetic imaging, ferroptosis inducing, and immunotherapeutic properties is fabricated using a simple coincubation method with macrophages being the bioreactor. Extremely small iron oxide nanoparticle (ESIONPs) incorporated exosomes (ESIONPs@EXO) are acquired by sorting the secreted exosomes from M1-polarized macrophages induced by ESIONPs...
February 27, 2024: ACS Nano
https://read.qxmd.com/read/38411934/recent-progress-in-enzymatic-preparation-of-chitooligosaccharides-with-a-single-degree-of-polymerization-and-their-potential-applications-in-the-food-sector
#30
REVIEW
Na Li, Yuting Lu, Xian Sheng, Yi Cao, Wei Liu, Zhi Zhou, Ling Jiang
Chitosan oligosaccharides (COS), derived from chitin, have garnered considerable attention owing to their diverse biological activities and potential applications. Previous investigations into the bioactivity of COS often encountered challenges, primarily stemming from the use of COS mixtures, making it difficult to discern specific effects linked to distinct degrees of polymerization (DP). Recent progress underscores the significant variation in the biological activities of COS corresponding to different DPs, prompting dedicated research towards synthesizing COS with well-defined polymerization...
February 27, 2024: Applied Biochemistry and Biotechnology
https://read.qxmd.com/read/38408499/functional-link-hybrid-artificial-neural-network-for-predicting-continuous-biohydrogen-production-in-dynamic-membrane-bioreactor
#31
JOURNAL ARTICLE
Ashutosh Kumar Pandey, Sarat Chandra Nayak, Sang-Hyoun Kim
Conventional machine learning approaches have shown limited predictive power when applied to continuous biohydrogen production due to nonlinearity and instability. This study was aimed at forecasting the dynamic membrane reactor performance in terms of the hydrogen production rate (HPR) and hydrogen yield (HY) using laboratory-based daily operation datapoints for twelve input variables. Hybrid algorithms were developed by integrating particle swarm optimized with functional link artificial neural network (PSO-FLN) which outperformed other hybrid algorithms for both HPR and HY, with determination coefficients (R2 ) of 0...
February 24, 2024: Bioresource Technology
https://read.qxmd.com/read/38408332/spatiotemporal-regulation-and-transport-engineering-for-sustainable-production-of-geraniol-in-candida-glycerinogenes
#32
JOURNAL ARTICLE
Cui Zhao, XiHui Wang, XinYao Lu, Hong Zong, Bin Zhuge
Geraniol is an attractive natural monoterpene with significant industrial and commercial value in the fields of pharmaceuticals, condiments, cosmetics, and bioenergy. The biosynthesis of monoterpenes suffers from the availability of key intermediates and enzyme-to-substrate accessibility. Here, we addressed these challenges in Candida glycerinogenes by a plasma membrane-anchoring strategy and achieved sustainable biosynthesis of geraniol using bagasse hydrolysate as substrate. On this basis, a remarkable 2...
February 26, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38403121/establishing-an-efficient-membrane-bioreactor-for-simultaneous-pollutant-removal-and-purple-bacteria-production-under-salinity-stress
#33
JOURNAL ARTICLE
Tianqi Hao, Yifeng Xu, Chuanzhou Liang, Xiaoshuai Peng, Siwei Yu, Lai Peng
Recovering resources from wastewater to alleviate the energy crisis has become the prevailing trend of technological development. Purple phototrophic bacteria (PPB), a group of fast-growing microbes, have been widely noticed for their potential in producing value-added products from waste streams. However, saline contents in these waste streams, such as food processing wastewater pose a big challenge, which not only restrain the pollutant removal efficiency, but also hinder the growth of functional microbes...
February 23, 2024: Chemosphere
https://read.qxmd.com/read/38402973/global-insight-into-the-occurrence-treatment-technologies-and-ecological-risk-of-emerging-contaminants-in-sanitary-sewers-effects-of-the-sars-cov-2-coronavirus-pandemic
#34
REVIEW
Heloisa Nascimento de Andrade, Jacineumo Falcão de Oliveira, Luciene Alves Batista Siniscalchi, Joseane Dunga da Costa, Ronaldo Fia
The SARS-CoV-2 pandemic caused changes in the consumption of prescribed/non-prescribed drugs and the population's habits, influencing the detection and concentration of emerging contaminants (ECs) in sanitary sewage and harming environmental and health risks. Therefore, the present work sought to discuss current literature data on the effects of the "COVID-19 pandemic factor" on the quality of raw sewage produced over a five-year period (2018-2019: pre-pandemic; 2020-2022: during the pandemic) and biological, physical, chemical and hybrid treatment technologies, influencing factors in the removal of ECs and potential ecological risks (RQs)...
February 23, 2024: Science of the Total Environment
https://read.qxmd.com/read/38401496/reducing-biosolids-from-a-membrane-bioreactor-system-assessing-the-effects-on-carbon-and-nutrient-removal-membrane-fouling-and-greenhouse-gas-emissions
#35
JOURNAL ARTICLE
Paulo Marcelo Bosco Mofatto, Alida Cosenza, Daniele Di Trapani, Giorgio Mannina
This study presents the effects on carbon and nutrient removal, membrane fouling and greenhouse gas (GHG) emissions of an Oxic-Settling-Anaerobic (OSA) - Membrane Bioreactor (MBR) pilot plant fed with real wastewater. The influence of three sludge return internal ratios (IR) was investigated by testing 45, 75 and 100%. The results showed that with the increase of IR, the biological sludge production substantially decreased by 85.8% due to the combination of cell lysis and endogenous metabolism. However, a worsening of ammonia removal efficiencies occurred (from 94...
February 23, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38395234/intensifying-the-simultaneous-removal-of-nitrogen-and-phosphorus-of-an-integrated-aerobic-granular-sludge-membrane-bioreactor-by-acinetobacter-junii
#36
JOURNAL ARTICLE
Weifeng Liang, Biao Yang, Liying Bin, Yadong Hu, Depeng Fan, Weirui Chen, Ping Li, Bing Tang
This work aims at intensifying the simultaneous removal of nitrogen and phosphorus of an integrated aerobic granular sludge (AGS) - membrane bioreactor (MBR) by Acinetobacter junii. After acclimation and enrichment in a sequencing batch reactor (SBR), Acinetobacter junii, a kind of denitrifying phosphate accumulating organism (DPAO), was successfully screened in the used SBR. Then it was verified to be capable of effectively enhancing the performance in the simultaneous removal of nitrogen and phosphorus of AGS-MBR...
February 21, 2024: Bioresource Technology
https://read.qxmd.com/read/38394916/an-integrated-meta-omics-approach-reveals-the-different-response-mechanisms-of-two-anammox-bacteria-towards-fluoroquinolone-antibiotics
#37
JOURNAL ARTICLE
Xuejiao Qiao, Lingyun Ding, Fang Fang, Chenkun Fu, Ruqian Wei, Yizhen Chen, Sihan Zheng, Xisong Wang, Yan Yan, Kai Yang, Nan Xu, Huchun Tao, Ke Yu, Lijuan Zhang
The emerging fluoroquinolone antibiotics (FQs) are highly influential in nitrogen removal from livestock wastewater. However, beyond the capability of nitrogen removal, little is known about the molecular mechanisms (e.g., shift of core metabolism and energy allocation) of different anaerobic ammonium-oxidizing bacteria (AnAOB) under continuous FQ stress. This study investigated the effects of ciprofloxacin, ofloxacin and their mixture at concentrations detected in livestock wastewater on two key anammox species in membrane bioreactors...
February 19, 2024: Environment International
https://read.qxmd.com/read/38382922/rna-synthesis-in-liposomes-with-negatively-charged-lipids-after-fusion-via-freezing-thawing
#38
JOURNAL ARTICLE
Gakushi Tsuji, Ayu Shimomura, Shota Fukuoka, Masaya Oki
The freezing-thawing (F/T) method for fusing giant unilamellar vesicles (GUVs) can provide substrates, enzymes and membrane material simultaneously and repetitively, and is useful for constructing a recursive model of an artificial cell. However, enzymatic efficiency after F/T is reduced due to rupture of the GUVs and leakage of the inner solution during F/T. Previously, liposomes composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and a negatively charged lipid, such as 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (POPG), showed lower rupture and leakage rates during F/T...
February 21, 2024: Genes & Genetic Systems
https://read.qxmd.com/read/38382609/mg-2-addition-unlocking-optimized-treatment-performance-and-anti-fouling-property-in-microalgal-bacterial-membrane-bioreactors
#39
JOURNAL ARTICLE
Fei Huang, Yu Zhao, Shilei Chen, Hongjun Lin, Jiaheng Teng, Xiang Cai, Meijia Zhang
While microalgal-bacterial membrane bioreactors (microalgal-bacterial MBRs) have risen as an important technique in the realm of sustainable wastewater treatment, the membrane fouling caused by free microalgae is still a significant challenge to cost-effective operation of the microalgal-bacterial MBRs. Addressing this imperative, the current study investigated the influence of magnesium ion (Mg2+ ) addition on the biological dynamics and membrane fouling characteristics of the laboratory-scale submerged microalgal-bacterial MBRs...
February 19, 2024: Science of the Total Environment
https://read.qxmd.com/read/38378066/second-life-of-water-and-wastewater-in-the-context-of-circular-economy-do-the-membrane-bioreactor-technology-and-storage-reservoirs-make-the-recycled-water-safe-for-further-use
#40
JOURNAL ARTICLE
Klaudia Stankiewicz, Piotr Boroń, Justyna Prajsnar, Mirosław Żelazny, Miłosz Heliasz, Walter Hunter, Anna Lenart-Boroń
In recent years water demand drastically increased which is particularly evident in tourism-burdened mountain regions. In these areas, climate neutral circular economy strategies to minimize human impact on the environment can be successfully applied. Among these strategies, treated wastewater reuse and retaining water in storage reservoirs deserve particular attention. This study aimed to determine if recycled water produced with two circular economy systems, namely membrane bioreactor treatment plant (MBR) with UV-light effluent disinfection and a storage reservoir, is safe enough for further use in green areas irrigation in summer and artificial snow production in winter...
February 18, 2024: Science of the Total Environment
keyword
keyword
160247
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.