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Hemoglobin variability mircera

Thomas Weinreich, Frank Leistikow, Hagen-Georg Hartmann, G√ľnter Vollgraf, Frank Dellanna
Once-monthly administration of CERA, a continuous erythropoietin receptor activator, has shown equivalent efficacy to shorter-acting erythropoiesis-stimulating agents (ESAs) that require more frequent dosing, but data on routine use of once-monthly CERA in hemodialysis patients are lacking. Study on Efficacy, Safety and Applicability of Mircera (SESAM) was a prospective, multicenter, noninterventional trial with a duration of up to 9 months (month 0-5 "titration phase"; month 6-8 "evaluation phase") to test the stability of Hb control in hemodialysis patients under routine conditions...
January 2012: Hemodialysis International
Nicholas M Selby, Sally A Fonseca, Richard J Fluck, Maarten W Taal
BACKGROUND AND OBJECTIVES: The extent to which hemoglobin (Hb) cycling occurs in peritoneal dialysis (PD) patients is unclear. It is also uncertain whether different types of erythropoiesis-stimulating agents (ESAs) affect such cycling. We performed a retrospective cohort study of our PD population before and after the entire program was switched from epoetin beta (NeoRecormon: Hoffman-LaRoche, Basel, Switzerland) to continuous erythropoietin receptor activator [CERA (Mircera: Hoffman-LaRoche)]...
March 2012: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
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