Read by QxMD icon Read

Hemoglobin variability

David A Hashemi, Zoe O Brown-Joel, Elizabeth Tkachenko, Caroline A Nelson, Megan H Noe, Sotonye Imadojemu, Ruth Ann Vleugels, Arash Mostaghimi, Karolyn A Wanat, Misha Rosenbach
Importance: Necrobiosis lipoidica (NL) is a rare granulomatous condition. Current knowledge of its key features is based on a limited number of studies and case reports, leading to wide variability in the characterization of its defining features, with limited comparison of patients with or without diabetes. Objective: To evaluate the epidemiologic characteristics, clinical features, and disease associations of NL in patients with or without type 1 or 2 diabetes...
February 20, 2019: JAMA Dermatology
Yang Zhao, Rui Hou, Xiu Zhu, Lihua Ren, Hong Lu
BACKGROUND: The majority of current evidences simply showed the short-term benefits of delayed cord clamping, mainly focusing on the first week after birth. Without follow-up data, we can hardly come to the conclusion that delayed cord clamping may do more harm than good. OBJECTIVE: To evaluate the long-term effects of delayed cord clamping compared with early cord clamping on infants after neonatal period. DESIGN: Systematic review and meta-analysis of randomized controlled trials (RCTs)...
February 8, 2019: International Journal of Nursing Studies
Ying Xiong, Shuoqi Zhang, Jingjing Shi, Yang Fan, Qiang Zhang, Wenzhen Zhu
BACKGROUND: Diffusion-tensor-imaging (DTI) is sensitive in detecting white matter changes in type-2 diabetes mellitus (T2DM). However, DTI indices can be affected by either neurite density or spatial variation. A novel diffusion MRI technique, termed neurite orientation dispersion and density imaging (NODDI), can provide distinct indices of fiber density and dispersion. PURPOSE: To characterize brain microstructural alterations in T2DM patients with mild cognitive impairment (MCI) using the NODDI model...
February 19, 2019: Journal of Magnetic Resonance Imaging: JMRI
Nashwa Othman, Osama Gheith, Torki Al-Otaibi, Tarek Mahmoud, Faisal Al-Refaei, Fatma Mahmoud, Heba Abduo, Narayanan Nampoory, Medhat A Halim, Ayman Najeb
OBJECTIVES: Diabetes knowledge among kidney transplant recipients with posttransplant diabetes has not been exhaustively assessed. We evaluated levels of diabetes knowledge among our kidney transplant patients using a 35-item diabetes self-care management questionnaire. MATERIALS AND METHODS: The study comprised renal transplant patients with posttransplant diabetes mellitus who were referred from Hamed Al-Essa Organ Transplant Center of Kuwait to the Dasman Diabetes Institute...
January 2019: Experimental and Clinical Transplantation
Hareram Pandey, Kanwaljeet Singh, Ravi Ranjan, Sanjay Kumar Pandey, Amit Sharma, Kamal Kishor, Tulika Seth, Manoranjan Mahapatra, Renu Saxena
INTRODUCTION: In sickle cell disease (SCD) patients, among the predictors of survival, HbF levels play a significant role in lowering the morbidity and mortality. Coinheritance of δβ thalassemia and hereditary persistence of fetal hemoglobin (HPFH) may contribute to variable HbF levels in SCD patients, thus influencing their clinicopathological profile. Such cases are sparsely documented in the literature and thus, we screened the presence of δβ thalassemia and HPFH in 126 cases of SCD with high HbF...
December 2019: Hematology (Amsterdam, Netherlands)
Ramakrishna Prasad, Abhiruchi Patki, Shibany Padhy, Gopinath Ramchandran
Background and Aims: Intraoperative use of a single bolus dose of tranexamic acid may not be sufficient to prevent bleeding in the early postoperative period. The present study was carried out to compare the effect of two dose regimens of tranexamic acid in reducing perioperative blood loss and the amount of allogenic blood transfusion in abdominal tumor surgery. Material and Methods: In this prospective, controlled, and double-blind investigation, 60 patients electively posted for abdominal oncosurgical procedures were randomly assigned to receive a single bolus dose of tranexamic acid (10 mg/kg) (Group A), a bolus dose of tranexamic acid (10 mg/kg) followed by infusion (1 mg/kg/h) till 4 h postoperatively (Group B), and a bolus followed by infusion of normal saline (group C)...
October 2018: Journal of Anaesthesiology, Clinical Pharmacology
Eisei Hori, Chigusa Kikuchi, Kenro Imaeda, Naotsuka Okayama, Tadashi Suzuki, Tamihide Matsunaga
It is reported that statins have inconsistent effects on glycemic status and adiponectin concentrations in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate the effect of statins on these variables in patients with T2DM and hypercholesterolemia. A control group comprising 24 patients with T2DM but without hypercholesterolemia was observed for more than 12 weeks, while 24 patients with T2DM and hypercholesterolemia were treated with statins for the same period (statin group). The percentage changes in the glycemic status (blood glucose and glycated hemoglobin [HbA1c]), and levels of plasma adiponectin (total and high molecular weight [HMW]) were compared between the two groups...
February 15, 2019: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
M J B Bezerra, J M Arruda-Alencar, J A M Martins, A G A Viana, A M Viana Neto, J P A Rêgo, R V Oliveira, M Lobo, A C O Moreira, R A Moreira, A A Moura
The present study was conducted to describe the major seminal plasma proteome of rabbits and potential associations between seminal proteins and semen criteria. Semen samples were collected from 18 New Zealand adult rabbits, and seminal plasma proteins were analyzed by 2-D SDS-PAGE and tandem mass spectrometry. Sperm motility, vigor, concentration, morphology and membrane sperm viability were evaluated. Rabbits ejaculated 364 ± 70 million sperm/ml, with 81 ± 6.1% motile cells, 3.8 ± 0.2 vigor and 66...
February 7, 2019: Theriogenology
Ansony R Godínez-Vidal, Itziar A Cinta-Egaña, Luis A Ornelas-Oñate, Diego M García-Vivanco, Gabriela E Gutiérrez-Uvalle, Noe I Gracida-Mancilla
Introduction: It is crucial the timely detection of a new infection or the persistence of it to improve the survival rates, there is no index that can determine the need for relaparotomy. Objective: To evaluate the diagnostic certainty of the model elaborated by Kiewiet-Van Ruler. Method: A retrospective, descriptive, cross-sectional study, patients diagnosed with abdominal sepsis who underwent exploratory laparotomy between January 2013 to and May 2015...
2019: Cirugia y Cirujanos
Junjie Hang, Junjie Huang, Siyuan Zhou, Lixia Wu, Yingwei Zhu, Lina Zhu, Hanyu Zhou, Kequn Xu, Hua Jiang, Xuguang Yang
Naïve and memory T cells play a pivotal role in solid tumor pathogenesis but their role in pancreatic cancer progression remains elusive. Thus, we aimed to investigate their clinical potential in advanced pancreatic cancer (APC). Flow cytometry was performed to evaluate the level of baseline peripheral naïve and memory T cells from 137 APC patients before receiving first-line chemotherapy. Interrelationships between naïve, memory T cells and clinicopathological variables were evaluated using Pearson's correlation...
February 14, 2019: Cancer Medicine
Michael E Steinhaus, Joshua Buksbaum, Avraham Eisenman, Monal Kohli, Austin T Fragomen, S Robert Rozbruch
Blood loss remains a significant source of morbidity and mortality in orthopaedic surgery, with transfusions associated with an increased risk of infection, length of stay, delayed rehabilitation, and significantly increased hospitalization costs. The purpose of this study was to assess whether the use of tranexamic acid (TXA) is effective in reducing postoperative blood loss in patients undergoing distal femoral osteotomy (DFO). A retrospective review was performed of all patients undergoing DFO by a single surgeon from 2010 to 2017, with a change in protocol occurring in 2014, after which all patients received TXA...
February 12, 2019: Journal of Knee Surgery
Kristen Tgavalekos, Thao Pham, Nishanth Krishnamurthy, Angelo Sassaroli, Sergio Fantini
We report a study on twenty-two healthy human subjects of the dynamic relationship between cerebral hemoglobin concentration ([HbT]), measured with near-infrared spectroscopy (NIRS) in the prefrontal cortex, and systemic arterial blood pressure (ABP), measured with finger plethysmography. [HbT] is a measure of local cerebral blood volume (CBV). We induced hemodynamic oscillations at discrete frequencies in the range 0.04-0.20 Hz with cyclic inflation and deflation of pneumatic cuffs wrapped around the subject's thighs...
2019: PloS One
Rachel L Usala, Stephen J Fernandez, Mihriye Mete, Nawar M Shara, Joseph G Verbalis
Context: Patients with diabetes mellitus are at increased risk for bone fragility fracture secondary to multiple mechanisms. Hyperglycemia can induce true dilutional hyponatremia. Hyponatremia is associated with gait instability, osteoporosis, and increased falls and bone fractures, and studies suggest that compromised bone quality with hyponatremia may be independent of plasma osmolality. We performed a case-control study of patients with diabetes mellitus matched by median glycated hemoglobin (HbA1c) to assess whether hyponatremia was associated with increased risk of osteoporosis and/or fragility fracture...
February 1, 2019: Journal of the Endocrine Society
Pablo Nejamkin, Verónica Cavilla, María Clausse, Florencia Landivar, Augusto M Lorenzutti, Sofía Martínez, María J Del Sole, Manuel Martín-Flores
OBJECTIVES: The aim of this study was to describe the sedative and some physiological effects of tiletamine-zolazepam following buccal administration (BA) in cats. METHODS: Seven healthy spayed European Shorthair cats (three males, four female) were studied twice in this randomized, blinded, crossover study. Each cat received two doses of tiletamine-zolazepam by BA: the low-dose (LD) consisted of 5 mg/kg of each drug, and the high dose (HD) consisted of 7.5 mg/kg of each...
February 12, 2019: Journal of Feline Medicine and Surgery
Aline Silva Santos Sena, Alex Sandro Rolland de Souza, Vivianne de Oliveira Barros, Maria do Carmo Pinto Lima, Adriana Suely Oliveira Melo, Melania Maria Ramos de Amorim
OBJECTIVE: To assess fetal visceral adiposity and associated factors during pregnancy. METHODS: Secondary analysis of prospective cohort data with 172 pairs (pregnant woman/fetus) treated at public health units. Anthropometric data, metabolic (glucose, glycated hemoglobin, insulin, insulin resistance, total cholesterol and fractions, triglycerides) measures, fetal biometry, and visceral and subcutaneous adiposity in the binomial (pregnant woman/fetus) were evaluated at the 16th, 28th and 36th gestational weeks by ultrasonography...
February 8, 2019: Jornal de Pediatria
G De Pergola, V A Giagulli, E Guastamacchia, N Bartolomeo, R Tatoli, L Lampignano, F Silvestris, V Triggiani
BACKGROUND AND AIMS: A significant increase in platelet count may be a risk factor for atherosclerotic cardiovascular disease. This study investigates the association between platelet number and glucose metabolism, evaluated by glycated hemoglobin (HbA1c) levels, in a apparently healthy population represented by overweight and obese subjects with normal glucose and HbA1c levels. METHODS AND RESULTS: As many as 240 subjects, 177 women and 63 men, aged 18-70 years, were enrolled...
January 3, 2019: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Álvaro Quiñones, Carla Ugarte, Claudia Chávez, Jaime Mañalich
BACKGROUND: Lack of adherence to treatment may hamper the management of type 2 Diabetes Mellitus. Aim To identify if there is a profile of psychological variables associated with adherence to treatment and complications in patients with type 2 diabetes mellitus. MATERIAL AND METHODS: The psychometric instruments Multidimensional Scale of Locus of Control in Health, Locus of Control of Rotter and Inventory of Temporary Orientation of Zimbardo & Boyd were applied to 192 patients aged 64 ± 10 years (78% women) with type 2 diabetes attending public primary health clinics...
December 2018: Revista Médica de Chile
Anne Klausing, Markus Martini, Matthias Dominik Wimmer, Sascha Gravius, Dieter Christian Wirtz, Thomas Martin Randau
BACKGROUND: Postoperative complications are the main consumers of technical, medical, and human resources. Especially in the field of elective joint replacement surgery, a specialized, easy-to-obtain, and cost-efficient preoperative stratification and risk-estimation model is missing. METHODS: With preoperatively surveyed patient parameters, we identified the most relevant parameters to predict postoperative medical complications. We devised a prospective risk model, measuring the individual probability for intermediate care unit (IMC) or intensive care unit (ICU) admission...
January 5, 2019: Journal of Arthroplasty
Júlia S A Cândido, Lidyane V Camelo, José Geraldo Mill, Paulo A Lotufo, Antonio Luiz P Ribeiro, Bruce B Duncan, Luisa C C Brant, Sandhi Maria Barreto
BACKGROUND: Arterial stiffness has been associated with renal dysfunction and its progression, but the pathophysiological relation underlying this association has not been fully established, particularly among individuals without hypertension and diabetes. We investigated the cross-sectional associations between arterial stiffness and renal function in adults without cardiovascular disease, and whether this association remained among subjects without hypertension and diabetes. METHODS: All eligible participants from ELSA-Brasil (2008-2010), aged 35 to 74 years (N = 13,586) were included, of whom 7,979 were free from hypertension and diabetes...
2019: PloS One
Francesco Fazio, Concetta Saoca, Vincenzo Ferrantelli, Gaetano Cammilleri, Gioele Capillo, Giuseppe Piccione
The authors investigated the arsenic (As) accumulation in different tissues (muscle, gill, liver, stomach, and intestine) and the possible correlation between tissue concentration and hematological parameters in mullet (Mugil cephalus Linnaeus, 1758) caught in Faro Lake (Messina, Sicily, Italy). On all fish, hematological analyses of blood samples, measurement of biometric indices, and the removal of the muscles, gills, liver, stomach, and intestine for the determination of arsenic concentration were performed...
February 2, 2019: Environmental Science and Pollution Research International
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"