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Raymond Fong, Nikie Sun, Yiu-Wing Ng, Anna F Rumbach, Elizabeth C Ward, Raymond Tsang
Dysphagia is a common sequela post chemo/radiotherapy for nasopharyngeal carcinoma (NPC), with cricopharyngeal dysfunction often a contributing factor. This study examined the impact of balloon dilation of the cricopharyngeus and cervical oesophagus on swallow competence for dysphagic patients with cricopharyngeal dysfunction post NPC. Patients with NPC were screened for dysphagia and cricopharyngeal dysfunction using fiberoptic endoscopic evaluation. Thirteen symptomatic patients, median 14.1 years post chemoradiotherapy for NPC, then underwent balloon dilation under local anesthesia...
March 19, 2019: Dysphagia
Michael-Alexander Malahias, Emmanouil Brilakis, Grigorios Avramidis, Emmanouil Antonogiannakis
PURPOSE: To answer the question whether arthroscopic subacromial balloon spacer (InSpace Balloon-ISB) implantation results in improved outcomes in patients suffering by irreparable massive rotator cuff tears (MRCT). Secondarily, we aimed to compare the outcomes of a combined ISB and arthroscopic partial repair procedure with those of a single ISB implantation without any repair. METHODS: A retrospective single-centre case series, based on prospectively collected data of patients who were suffering by irreparable MRCT, was conducted...
March 19, 2019: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Jonathan F McAnulty, Casey Budgeon, Kenneth R Waller
CASE DESCRIPTION: A 6-year-old neutered male mixed-breed dog (dog 1) and 5-year-old neutered male Boston Terrier (dog 2) were evaluated because of lateralized multilobular osteochondrosarcoma (MLO) of the occiput. CLINICAL FINDINGS: Diagnostic imaging revealed proliferative bony occipital masses in both dogs and a nodule in the right caudal lung lobe of dog 1. For both dogs, MRI revealed intact flow through the dorsal sagittal sinus (DSS) into 1 transverse sinus...
April 1, 2019: Journal of the American Veterinary Medical Association
Poul Erik Andersen, Stevo Duvnjak, Oke Gerke, Anette Drøhse Kjeldsen
PURPOSE: The present study is a register-based observational study of an unselected consecutive patient cohort with pulmonary arteriovenous malformations (PAVMs) from a single national hereditary hemorrhagic telangiectasia and PAVM embolization center. The aim was to investigate the frequency of re-embolizations and the clinical outcome after embolization with the use of different embolization materials further, to define which PAVM morphology and size of feeding arteries that most often were re-embolized, and to estimate the clinical outcome of the patients including those that were re-embolized...
March 18, 2019: Cardiovascular and Interventional Radiology
Juan F Granada, Renu Virmani, Daniel Schulz-Jander, Stefan Tunev, Robert J Melder
Two different drug-coated balloons (DCBs) possessing different coating formulations were compared for rate of coating dissolution in vitro, in addition to tissue drug concentration and histological responses of treated vascular tissue in vivo, to determine if the rate of drug bioavailability to vascular tissue can impact the degree and duration of the observed pharmacological response to locally delivered drug. In vitro dissolution comparison demonstrated that a urea/paclitaxel-based coating formulation (IN...
2019: Journal of Drug Delivery
Maxwell S Renna, Cristiano van Zeller, Farah Abu-Hijleh, Cherlyn Tong, Jasmine Gambini, Mengyao Ma
Introduction: Major trauma is a leading cause of death and disability in young adults, especially from massive non-compressible torso haemorrhage. The standard technique to control distal haemorrhage and maximise central perfusion is resuscitative thoracotomy with aortic cross-clamping (RTACC). More recently, the minimally invasive technique of resuscitative endovascular balloon occlusion of the aorta (REBOA) has been developed to similarly limit distal haemorrhage without the morbidity of thoracotomy; cost-utility studies on this intervention, however, are still lacking...
January 2019: Trauma
R Thomas Collins, Richard D Mainwaring, Kirstie L MacMillen, Frank L Hanley
BACKGROUND: To evaluate the short- and mid-term outcomes of surgical pulmonary artery reconstruction in patients with Williams syndrome. METHODS: We performed a retrospective cohort study of all patients with Williams syndrome who underwent surgical pulmonary artery reconstruction at Lucile Packard Children's Hospital between January 2001 and May 2018. RESULTS: There were 25 WS patients (52% female) who underwent pulmonary artery reconstruction during the study period...
March 15, 2019: Annals of Thoracic Surgery
Justin M McGinnis, Natasha K Simula, K S Joseph, Jagdeep S Ubhi
OBJECTIVE: Placenta accreta syndromes are well-recognized risk factors for severe postpartum hemorrhage and are associated with significant maternal morbidity. Internal iliac artery balloon tamponade is an adjunctive procedure used to reduce blood loss at the time of Caesarean hysterectomy with variable results in the reported literature. This study investigated the outcomes of preoperative balloon tamponade at the largest tertiary referral centre for placenta accreta in British Columbia...
April 2019: Journal of Obstetrics and Gynaecology Canada: JOGC
Gao Sun, Charles V Jackson, Karen Zimmerman, Li-Kun Zhang, Courtney M Finnearty, George E Sandusky, Guodong Zhang, Richard G Peterson, Yi-Xin Jim Wang
BACKGROUND: Metabolic disorders such as insulin resistance, obesity, and hyperglycemia are prominent risk factors for the development of non-alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH). Dietary rodent models employ high fat, high cholesterol, high fructose, methionine/choline deficient diets or combinations of these to induce NAFLD/NASH. The FATZO mice spontaneously develop the above metabolic disorders and type 2 diabetes (T2D) when fed with a normal chow diet. The aim of the present study was to determine if FATZO mice fed a high fat and fructose diet would exacerbate the progression of NAFLD/NASH...
March 18, 2019: BMC Gastroenterology
Dietmar Boethig, Alexander Horke, Mark Hazekamp, Bart Meyns, Filip Rega, Joeri Van Puyvelde, Michael Hübler, Martin Schmiady, Anatol Ciubotaru, Giovanni Stellin, Massimo Padalino, Viktor Tsang, Ramadan Jashari, Dmitry Bobylev, Igor Tudorache, Serghei Cebotari, Axel Haverich, Samir Sarikouch
OBJECTIVES: Decellularized pulmonary homografts (DPH) have shown excellent results for pulmonary valve replacement. However, controlled multicentre studies are lacking to date. METHODS: Prospective European multicentre trial evaluating DPH for pulmonary valve replacement. Matched comparison of DPH to bovine jugular vein (BJV) conduits and cryopreserved homografts (CH) considering patient age, type of heart defect and previous procedures. RESULTS: In total, 121 patients (59 female) were prospectively enrolled (August 2014-December 2016), age 21...
March 15, 2019: European Journal of Cardio-thoracic Surgery
Yukio Aikawa, Teruo Noguchi, Yoshiaki Morita, Emi Tateishi, Atsushi Kono, Hiroyuki Miura, Yoshiaki Komori, Yasuhide Asaumi, Tetsuya Fukuda, Satoshi Yasuda
AIMS: To investigate the clinical impact of T1 mapping for detecting myocardial impairment in takotsubo cardiomyopathy (TTC) over time. METHODS AND RESULTS: In 23 patients with the apical ballooning type of TTC, the following 3T magnetic resonance (MR) examinations were performed at baseline and 3 months after TTC onset: T2-weighted imaging, T2 mapping, native T1 mapping, extracellular volume fraction (ECV), and late gadolinium enhancement. Eight healthy controls underwent the same MR examinations...
March 16, 2019: European Heart Journal Cardiovascular Imaging
Natalia Briceno, Kalpa De Silva, Matthew Ryan, Tiffany Patterson, Kevin O'Gallagher, Howard Ellis, Simone Rivolo, Jack Lee, Simon Redwood, Ajay M Shah, Michael Marber, Divaka Perera
The effect of intra-aortic balloon counterpulsation (IABC) varies, and it is unknown whether this is due to a heterogeneous coronary physiological response. This study aimed to characterise the coronary and left ventricular (LV) effects of IABC and define responders in terms of their invasive physiology. Twenty-seven patients (LVEF 31 ± 9%) underwent coronary pressure and Doppler flow measurements in the target vessel and acquisition of LV pressure volume loops after IABC supported PCI, with and without IABC assistance...
March 15, 2019: Journal of Cardiovascular Translational Research
Jianhong Wang, Shu Yang, Xiaofan Yuan, Fuqiang Guo
BACKGROUND: There is a new research reported that the technology for navigating the catheter, which is eccentric or tangentially angled to the long axis of a CAS(Carotid Artery Stent). In the clinical practices, we found that there is still existed resistance when the 8F guiding catheter crossing the balloon, even if it is partially expanded. Therefore, we intended to improve the operating procedure by utilizing a smaller balloon with a diameter of 2 mm. The smaller balloon can navigate the guiding catheter re-access the angled junction with minimal resistance after it is fully expanded...
March 12, 2019: World Neurosurgery
Gianmarco de Donato, Edoardo Pasqui, Francesco Setacci, Giancarlo Palasciano, Laura Nigi, Cecilia Fondelli, Antonio Sterpetti, Francesco Dotta, George Weber, Carlo Setacci
After the invention of the balloon catheter by Fogarty in 1963, surgical thromboembolectomy was considered the gold standard treatment for many years in patients with acute lower limb ischemia (ALLI). ALLI is a dramatic event, carrying a high risk of amputation and perioperative morbidity and mortality. The evolution of endovascular technologies has resulted in a variety of therapeutic options to establish arterial patency. In the 1970s, Dotter first introduced the idea of clot lysis in the treatment of ALLI, which was modified to catheter-directed thrombolysis, and now clot aspiration techniques...
June 2018: Seminars in Vascular Surgery
Angelo Argenteri, Gianmarco de Donato, Francesco Setacci, Domenico Benevento, Enrico Maria Marone, Giancarlo Palasciano, Carlo Setacci
The history of the recognition and surgical treatment of lower limb ischemia dates back to the Middle Ages. The twin Saints Comas and Damian were ascribed to have saved a gangrenous limb in the 13th century and became patrons of future surgeons. The physicians that followed developed the theories of blood flow, anatomy of the arterial circulation, and recognition that occlusive disease was the cause of limb ischemia and gangrene. Innovative physicians developed the techniques of arterial surgery and bypass grafting to restore limb blood flow and allow healing of lesions...
June 2018: Seminars in Vascular Surgery
Andreas Schörghofer, Martin Drerup, Thomas Kunit, Lukas Lusuardi, Josef Holzinger, Josef Karner, Michael Groher, Christoph Zoubek, Rosemarie Forstner, Felix Sedlmayer, Frank Wolf
BACKGROUND: Rectal spacers are used to limit dose to the anterior rectal wall in high dose external beam radiation therapy of the prostate and have been shown to reduce radiation induced toxicity. Here we report the complication rate and toxicity of the implantation procedure in a large cohort of patients who have either received a gel- or balloon-type spacer. METHODS: In total, 403 patients received rectal spacing, 264 with balloon, 139 with gel. Allocation was non-randomized...
March 15, 2019: Radiation Oncology
Jin-Choon Lee, Min-Sik Kim, Dong-Jo Kim, Da-Hee Park, Il-Woo Lee, Hwan-Jung Roh, Byung-Joo Lee, Young-A Kim, Sunghwa Ko, Eui-Suk Sung
OBJECTIVE: The incidence of SGS has been reported to be less than 8% after endotracheal intubation. Therefore there is an increasing trend in the number of patients with acute acquired SGS due to mechanical ventilation in the intensive care unit. However, there have been no reports describing the treatment of SGS in children in South Korea. The objective of this study was to evaluate the management and outcomes of children with SGS at a pediatric tertiary center in South Korea over an 8-year period...
February 27, 2019: International Journal of Pediatric Otorhinolaryngology
T Herta, U Beuers
BACKGROUND: Immune-mediated cholangiopathies comprise primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and IgG4-associated cholangitis (IAC). A common feature is the progressive destruction of bile ducts leading to cholestasis with fibrosis and cirrhosis of the liver over time. The diseases are mostly identified during routine laboratory testing. Clinical signs and symptoms such as pruritus, fatigue or jaundice are infrequent in the early stage. DIAGNOSIS: The diagnostic work-up involves the patient's history, physical examination, serological tests, abdominal ultrasonography, magnetic resonance cholangiopancreatography (MRCP) and, where necessary, liver biopsy and genetic testing...
March 15, 2019: Der Radiologe
Sezen Atik Ugan, Selman Gökalp, Betül Çınar, İrfan Levent Saltık
OBJECTIVE: Right-heart catheterization using the antecubital veins has recently regained attention, and studies demonstrating the feasibility and safety of antecubital access in adults have been published. However, no changes have been observed in the preferred entrance sites in right-heart catheterizations in children with congenital heart diseases. This article is a description of the technique and features of the antecubital venous approach in pediatric patients with complex congenital heart defects and a Glenn anastomosis...
March 2019: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Masahiko Fujihara, Amane Kozuki, Yoshinori Tsubakimoto, Mitsuyoshi Takahara, Yoshiaki Shintani, Masashi Fukunaga, Yusuke Iwasaki, Tatsuya Nakama, Yoshiaki Yokoi
PURPOSE: To assess calcium patterns in superficial femoral artery (SFA) disease before and after balloon angioplasty ± stent implantation using fluoroscopy, angiography, and intravascular ultrasound (IVUS) imaging and then correlate calcification severity and midterm clinical outcomes. MATERIALS AND METHODS: A multicenter investigation was carried out to retrospectively review 130 symptomatic patients (mean age 73.2±8.4 years; 86 men) with de novo SFA lesions who had successfully undergone endovascular therapy (EVT) at 7 centers between January and October 2015...
March 15, 2019: Journal of Endovascular Therapy
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