Naianda Rezende Ribeiro, Lucas Magno Oliveira Santos, Scarleth Silva Costa, Carolina Kei Myasaki, Daniela Pagliara Lage, Vivian Tamietti Martins, Rory Cristiane Fortes De Brito, Larissa Chaves Freire, Ana Maria Ravena Severino Carvalho, Bryan Victor Serafim Brigido, Ricardo José Alves, Eduardo Antonio Ferraz Coelho, Bruno Mendes Roatt, Daniel Menezes-Souza, Mariana Costa Duarte
In the context of neglected diseases, tegumentary leishmaniasis (TL) presents an emerging and re-emerging character in the national territory and in the world. The treatment of TL has limitations, such as intravenous administration route, high toxicity, and high treatment costs. Thus, several researchers work on new therapeutic strategies to improve the effectiveness of the treatment of leishmaniasis. In this light, the present study used a topical formulation, containing 8-hydroquinoline (8-HQN), for the treatment of Balb/c mice infected with L...
April 26, 2024: European Journal of Pharmaceutics and Biopharmaceutics